Effect of CYP2D6*10 on the pharmacokinetics of R- and S-carvedilol in healthy Japanese volunteers

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 8, 2005, Pages 1476-1479

  Honda, Mutsuko ^a   Nozawa, Takashi ^b   Igarashi, Norio ^b   Inoue, Hiroshi ^b   Arakawa, Rie ^a   Ogura, Yumi ^a   Okabe, Hiromi ^a   Taguchi, Masato ^a   Hashimoto, Yukiya ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Bayesian analysis; Carvedilol; Cyp2d6*10; Pharmacokinetics

Indexed keywords

'ARTIST'; CARVEDILOL; CYTOCHROME P450 2D6; CARBAZOLE DERIVATIVE; PROPANOLAMINE DERIVATIVE;

ADULT; ALLELE; ARTICLE; BAYES THEOREM; BLOOD SAMPLING; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; ENANTIOMER; ENZYME ACTIVITY; ETHNIC GROUP; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOMERISM; LIVER METABOLISM; MALE; MATHEMATICAL MODEL; NORMAL HUMAN; STATISTICAL SIGNIFICANCE; BLOOD; JAPAN; METABOLISM; REFERENCE VALUE; STEREOISOMERISM;

ADULT; CARBAZOLES; CYTOCHROME P-450 CYP2D6; FEMALE; HUMANS; JAPAN; MALE; PROPANOLAMINES; REFERENCE VALUES; STEREOISOMERISM;

EID: 25644435489     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.28.1476     Document Type: Article

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