Combination therapy with carvedilol and amiodarone in patients with severe heart failure

European Journal of Heart Failure

Volumn 2, Issue 1, 2000, Pages 71-79

  Nägele, Herbert ^a   Bohlmann, Michael ^a   Eck, Ulrich ^a   Petersen, Ben ^a   Rödiger, Wilfried ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Amiodarone; Carvedilol; Heart failure; Heart transplantation; Sudden death

Indexed keywords

AMIODARONE; CAPTOPRIL; CARVEDILOL; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; FUROSEMIDE;

ADULT; ARTICLE; ATRIOVENTRICULAR BLOCK; BRADYCARDIA; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; FEMALE; HEART ATRIUM FIBRILLATION; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PACING; HEART RATE; HEART SINOATRIAL BLOCK; HEART TRANSPLANTATION; HEART VENTRICLE EXTRASYSTOLE; HOLTER MONITORING; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINUS BRADYCARDIA; TREATMENT OUTCOME;

ADRENERGIC BETA-ANTAGONISTS; AMIODARONE; ANTI-ARRHYTHMIA AGENTS; CARBAZOLES; DRUG THERAPY, COMBINATION; ELECTROCARDIOGRAPHY; FEMALE; HEART FAILURE, CONGESTIVE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MIDDLE AGED; PACEMAKER, ARTIFICIAL; PROGNOSIS; PROPANOLAMINES; TREATMENT OUTCOME;

EID: 0342803641     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-9842(99)00071-9     Document Type: Article

References (39)

1. Stevenson L.W., Warner S.L., Steimle A.E. et al. The impending crisis awaiting cardiac transplantation. Modeling a solution based on selection. Circulation. 89:1994;450-457.
2. Stevenson L.W. Tailored therapy before transplantation for treatment of advanced heart failure: effective use of vasodilators and diuretics. J Heart Lung Transplant. 10:1991;468-476.
3. McManus R.P., O'Hair D.P., Beitzinger J.M. et al. Patients who die awaiting heart transplantation. J Heart Lung Transplant. 12:1993;159-172.
4. Effects of enalapril on mortality in severe heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med. 316:1987;293-302.
5. Packer M., Bristow M.R., Cohn J.N. et al. Effect of carvedilol on morbidity and mortality in chronic heart failure. N Engl J Med. 334:1996;1349-1355.
6. Beta-blockers improve survival in mild to moderate CHF. Lancet. 353(2):1999;9-13.
7. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet. 353:1999;2001-2007.
8. Pitt B., Zannad F., Remme W.J. et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med. 341:1999;709-717.
9. Stevenson W.G., Sweeney M.O. Arrhythmias and sudden death in heart failure. Jpn Circ J. 61:1997;727-740.
10. Nägele H., Rödiger W. Sudden death and tailored medical therapy in elective candidates for heart transplantation. J Heart Lung Transplant. 18:1999;869-876.
11. Moss A.J., Hall J., Cannom D.S. et al. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. N Engl J Med. 335:1996;1933-1940.
12. Reiffel J.A. Prolonging survival by reducing arrhythmic death: pharmacologic therapy of ventricular tachycardia and fibrillation. Am J Cardiol. 80(8A):1997;45G-55G.
13. Ruskin J.N. The cardiac arrhythmia suppression trial (CAST). N Engl J Med. 321:1989;386-388.
14. Mason J.W. Drug therapy-amiodarone. N Engl J Med. 316:1987;455-466.
15. Mattioni T.A., Zheutlin T.A., Sarmiento J.J., Parker M., Lesch M., Kehoe R.F. Amiodarone in patients with previous drug-mediated torsade de pointes. Long-term safety and efficacy. Ann Intern Med. 111:1989;574-580.
16. Mahmarian J.J., Smart F.W., Moye L.A. et al. Exploring the minimal dose of amiodarone with antiarrhythmic and hemodynamic activity. Am J Cardiol. 74:1994;681-686.
17. Massie B.M., Fisher S.G., Deedwania P.C., Singh B.N., Fletcher R.D., Singh S.N. Effect of amiodarone on clinical status and left ventricular function in patients with congestive heart failure. CHF-STAT investigators. Circulation. 93:1996;2128-2134.
18. Doval H.C., Nul D.R., Grancelli H.O., Perrone S.V., Bortman G.R., Curiel R. Randomised trial of low-dose amiodarone in severe congestive heart failure. Grupo de Estudio de la Sobrevida en la Insuficiencia Cardiaca en Argentina (GESICA). Lancet. 344:1994;493-498.
19. Singh S.N., Fletcher R.D., Fisher S.G. et al. Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia. Survival trial of antiarrhythmic therapy in congestive heart failure. N Engl J Med. 333:1995;77-82.
20. Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomised trials. Amiodarone Trials Meta-Analysis Investigators. Lancet. 350:1997;1417-1424.
21. Julian D.G., Camm A.J., Frangin G. et al. Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT. European Myocardial Infarct Amiodarone Trial Investigators. Lancet. 349:1997;667-674.
22. Janse M.J., Malik M., Camm A.J., Julian D.G., Frangin G.A., Schwartz P.J. Identification of post acute myocardial infarction patients with potential benefit from prophylactic treatment with amiodarone. A substudy of EMIAT (the European Myocardial Infarct Amiodarone Trial). Eur Heart J. 19:1998;85-95.
23. Kennedy H.L. Beta blockade, ventricular arrhythmias, and sudden cardiac death. Am J Cardiol. 80(9B):1997;29J-34J.
24. Derrida J.P., Ollagnier J., Benaim R., Haiat R., Chiche P. Amiodarone et propranolol: une association dangereuse? Nouv Presse Med. 8:1979;1429.
25. Luu M., Stevenson W.G., Stevenson L.W., Baron K., Walden J. Diverse mechanisms of unexpected cardiac arrest in advanced heart failure. Circulation. 80:1989;1675-1680.
26. Läer S., Scholz H., Buschmann I., Thoenes M., Meinertz T.h. Digitoxin intoxication during concomitant use of amiodarone. Eur J Clin Pharmacol. 54:1998;95-96.
27. O'Reilly R.A., Trager W.F., Rettie A.E., Goulart D.A. Interaction of amiodarone with racemic warfarin and its separated enantiomorphs in humans. Clin Pharmacol Ther. 42:1987;290-294.
28. Nägele H., Rödiger W. Long-term holter-monitoring in patients with reduced left ventricular function with MARK 1A. J Card Electrother Diagn Intervent Electrophysiol. 18:1998;2-12.
29. Jackson P.C., Allen-Narker R., Davies E.R., Rees J.R., Wilde P., Watt I. The assessment of an edge detection algorithm in determining left ventricular ejection fraction using radio-nuclide multiple gated acquisition and contrast ventriculography. Eur J Nucl Med. 7:1982;62-65.
30. Stevenson L.W. Patient selection for mechanical bridging to transplantation. Ann Thorac Surg. 61:1996;380-387.
31. Tonet J., Frank R., Fontaine G., Grosgogeat Y. Efficacy and safety of low doses of beta-blocker agents combined with amiodarone in refractory ventricular tachycardia. Pacing Clin Electrophysiol. 11:1988;1984-1989.
32. Polster P., Broekhuysen J. The adrenergic antagonism of amiodarone. Biochem Pharmacol. 25:1976;131-134.
33. Björnerheim R., Froeysaker T., Hansson V. Effects of chronic amiodarone treatment on human myocardial β adrenoceptor density and adenylate cyclase response. Cardiovasc Res. 25:1991;503-509.
34. Sager P.T. Modulation of antiarrhythmic drug effects by beta-adrenergic sympathetic stimulation. Am J Cardiol. 82:1998;20I-30I.
35. Tonet J., Hidden F., Naditch L., Coutte R., Himbert C., Frank R. Combination of celiprolol and amiodarone in the treatment of recurrent ventricular tachycardia. Ann Cardiol Angeiol Paris. 45:1996;18-23.
36. Crijns H.J., Van den Berg M.P., Van Gelder I.C., Van Veldhuisen D.J. Management of atrial fibrillation in the setting of heart failure. Eur Heart J. 18(Suppl C):1997;C45-C49.
37. Skanes A.C., Morton B.C., Green M.S., Tang A.S. Torsade de pointes with amiodarone in a patient with previous torsade during beta-receptor blockade. Can J Cardiol. 13:1997;383-386.
38. Nägele H, Appl U, Rödiger W. Pacemaker therapy in severe heart failure. The 'APIC' study. Proceedings of the VI Asian-Pacific symposium on cardiac pacing and electrophysiology. Sethi KK Hrsg, 1997:209-213.
39. Nägele H., Appl U., Rödiger W. Implications of long-term pacemaker holter monitoring of patients with terminal heart failure submitted for heart transplantation. J Am Coll Cardiol. 31(2 Suppl. A):1998;388A.