-
1
-
-
0141528828
-
Chronic myeloid leukemia-advances in biology and new approaches to treatment
-
Goldman JM, Melo JV. Chronic myeloid leukemia-advances in biology and new approaches to treatment. N Engl J Med 2003; 349(15):1451-1464.
-
(2003)
N. Engl. J. Med.
, vol.349
, Issue.15
, pp. 1451-1464
-
-
Goldman, J.M.1
Melo, J.V.2
-
2
-
-
0141956039
-
The chronic myeloproliferative disorders: An historical perspective
-
Steensma DP. The chronic myeloproliferative disorders: an historical perspective. Curr Hematol Rep 2003; 2(3):221-230.
-
(2003)
Curr. Hematol. Rep.
, vol.2
, Issue.3
, pp. 221-230
-
-
Steensma, D.P.1
-
3
-
-
10744223441
-
Sudden onset of the blastic phase of chronic myelogenous leukemia: Patterns and implications
-
Kantarjian H, O'Brien S, Cortes J et al. Sudden onset of the blastic phase of chronic myelogenous leukemia: patterns and implications. Cancer 2003; 98(1):81-85.
-
(2003)
Cancer
, vol.98
, Issue.1
, pp. 81-85
-
-
Kantarjian, H.1
O'Brien, S.2
Cortes, J.3
-
4
-
-
0041917185
-
Effects of age on prognosis with imatinib mesylate therapy for patients with Philadelphia chromosome-positive chronic myelogenous leukemia
-
Cortes J, Talpaz M, O'Brien S et al. Effects of age on prognosis with imatinib mesylate therapy for patients with Philadelphia chromosome-positive chronic myelogenous leukemia. Cancer 2003; 98(6):1105-1113.
-
(2003)
Cancer
, vol.98
, Issue.6
, pp. 1105-1113
-
-
Cortes, J.1
Talpaz, M.2
O'Brien, S.3
-
5
-
-
0141563723
-
Analysis of the impact of imatinib mesylate therapy on the prognosis of patients with Philadelphia chromosome-positive chronic myelogenous leukemia treated with interferon-alpha regimens for early chronic phase
-
Kantarjian H, O'Brien S, Cortes J et al. Analysis of the impact of imatinib mesylate therapy on the prognosis of patients with Philadelphia chromosome-positive chronic myelogenous leukemia treated with interferon-alpha regimens for early chronic phase. Cancer 2003; 98(7):1430-1437.
-
(2003)
Cancer
, vol.98
, Issue.7
, pp. 1430-1437
-
-
Kantarjian, H.1
O'Brien, S.2
Cortes, J.3
-
7
-
-
0037403952
-
Trends in leukemia incidence and survival in the United States (1973-1998)
-
Erratum in: Cancer 1993; 98(3):659
-
Xie Y, Davies SM, Xiang Y, Robison LL, Ross JA. Trends in leukemia incidence and survival in the United States (1973-1998). Cancer 2003; 97(9):2229-2235. Erratum in: Cancer 1993; 98(3):659.
-
(2003)
Cancer
, vol.97
, Issue.9
, pp. 2229-2235
-
-
Xie, Y.1
Davies, S.M.2
Xiang, Y.3
Robison, L.L.4
Ross, J.A.5
-
8
-
-
0037400564
-
A randomized study comparing interferon (IFN alpha) plus low-dose cytarabine and interferon plus hydroxyurea (HU) in early chronic phase chronic myeloid leukemia (CML)
-
Kuhr T, Burgstaller S, Apfelbeck U et al. A randomized study comparing interferon (IFN alpha) plus low-dose cytarabine and interferon plus hydroxyurea (HU) in early chronic phase chronic myeloid leukemia (CML). Leuk Res 2003; 27(5):405-411.
-
(2003)
Leuk. Res.
, vol.27
, Issue.5
, pp. 405-411
-
-
Kuhr, T.1
Burgstaller, S.2
Apfelbeck, U.3
-
9
-
-
0041466445
-
Specific targeted therapy of chronic myelogenous leukemia with imatinib
-
Deininger MW, Druker BJ. Specific targeted therapy of chronic myelogenous leukemia with imatinib. Pharmacol Rev 2003; 55(3):401-423.
-
(2003)
Pharmacol. Rev.
, vol.55
, Issue.3
, pp. 401-423
-
-
Deininger, M.W.1
Druker, B.J.2
-
10
-
-
23944466708
-
Real-time PCR quantification of bcr/abl chimera and WT1 genes in chronic myeloid leukemia
-
Fujii T, Inoue S, Karashima T et al. Real-time PCR quantification of bcr/abl chimera and WT1 genes in chronic myeloid leukemia. Rinsho Byori 2003; 51(9):839-846.
-
(2003)
Rinsho Byori
, vol.51
, Issue.9
, pp. 839-846
-
-
Fujii, T.1
Inoue, S.2
Karashima, T.3
-
11
-
-
0038700994
-
Cytogenetic and molecular mechanisms of resistance to imatinib
-
Hochhaus A. Cytogenetic and molecular mechanisms of resistance to imatinib. Semin Hematol 2003; 40(2 Suppl 3):69-79.
-
(2003)
Semin. Hematol.
, vol.40
, Issue.2 SUPPL. 3
, pp. 69-79
-
-
Hochhaus, A.1
-
12
-
-
0035800507
-
Clinical resistance to STI -571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K et al. Clinical resistance to STI -571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001; 293(5531):876-880.
-
(2001)
Science
, vol.293
, Issue.5531
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
13
-
-
0001686739
-
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
-
Shah NP, Nicoll JM, Nagar B et al. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell 2002; 2(2):117-125.
-
(2002)
Cancer Cell
, vol.2
, Issue.2
, pp. 117-125
-
-
Shah, N.P.1
Nicoll, J.M.2
Nagar, B.3
-
14
-
-
0037677447
-
Sensitive and quantitative detection of mutations associated with clinical resistance to STI-571
-
Liu WH, Makrigiorgos GM. Sensitive and quantitative detection of mutations associated with clinical resistance to STI-571. Leuk Res 2003; 27(11):979-982.
-
(2003)
Leuk. Res.
, vol.27
, Issue.11
, pp. 979-982
-
-
Liu, W.H.1
Makrigiorgos, G.M.2
-
15
-
-
0037514458
-
Resistance of Philadelphia-chromosome positive leukemia towards the kinase inhibitor imatinib (STI571, Glivec): A targeted oncoprotein strikes back
-
von Bubnoff N, Peschel C, Duyster J. Resistance of Philadelphia-chromosome positive leukemia towards the kinase inhibitor imatinib (STI571, Glivec): a targeted oncoprotein strikes back. Leukemia 2003; 17(5):829-838.
-
(2003)
Leukemia
, vol.17
, Issue.5
, pp. 829-838
-
-
von Bubnoff, N.1
Peschel, C.2
Duyster, J.3
-
16
-
-
10744232328
-
Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P -loop) are associated with a poor prognosis
-
Branford S, Rudzki Z, Walsh S et al. Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P -loop) are associated with a poor prognosis. Blood 2003; 102(1):276-283.
-
(2003)
Blood
, vol.102
, Issue.1
, pp. 276-283
-
-
Branford, S.1
Rudzki, Z.2
Walsh, S.3
-
17
-
-
0036678472
-
Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop
-
Roumiantsev S, Shah NP, Gorre ME et al. Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop. Proc Natl Acad Sci USA 2002; 99(16):10700-10705.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.16
, pp. 10700-10705
-
-
Roumiantsev, S.1
Shah, N.P.2
Gorre, M.E.3
-
18
-
-
0038700992
-
Mutations in the ABL kinase domain pre-exist the onset of imatinib treatment
-
Roche-Lestienne C, Preudhomme C. Mutations in the ABL kinase domain pre-exist the onset of imatinib treatment. Semin Hematol 2003; 40(2 Suppl 3):80-82.
-
(2003)
Semin. Hematol.
, vol.40
, Issue.2 SUPPL. 3
, pp. 80-82
-
-
Roche-Lestienne, C.1
Preudhomme, C.2
-
19
-
-
0037254419
-
Imatinib alone and in combination for chronic myeloid leukemia
-
Druker BJ. Imatinib alone and in combination for chronic myeloid leukemia. Semin Hematol 2003; 40(1):50-58.
-
(2003)
Semin. Hematol.
, vol.40
, Issue.1
, pp. 50-58
-
-
Druker, B.J.1
-
20
-
-
0036320754
-
In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia
-
La Rosee P, Johnson K, O'Dwyer ME, Druker BJ. In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia. Exp Hematol 2002; 30(7):729-737.
-
(2002)
Exp. Hematol.
, vol.30
, Issue.7
, pp. 729-737
-
-
La Rosee, P.1
Johnson, K.2
O'Dwyer, M.E.3
Druker, B.J.4
-
21
-
-
0036682481
-
Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment
-
Roche-Lestienne C, Soenen-Cornu V, Grardel-Duflos N et al. Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment. Blood 2002; 100(3):1014-1018.
-
(2002)
Blood
, vol.100
, Issue.3
, pp. 1014-1018
-
-
Roche-Lestienne, C.1
Soenen-Cornu, V.2
Grardel-Duflos, N.3
-
23
-
-
0042360542
-
Chronic myeloid leukemia: Pathophysiology, diagnostic parameters, and current treatment concepts
-
Sillaber C, Mayerhofer M, Agis H, Sagaster V et al. Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts. Wien Klin Wochenschr 2003; 115(13-14):485-504.
-
(2003)
Wien. Klin. Wochenschr.
, vol.115
, Issue.13-14
, pp. 485-504
-
-
Sillaber, C.1
Mayerhofer, M.2
Agis, H.3
Sagaster, V.4
-
24
-
-
10744226050
-
Chronic myeloid leukemia patients resistant to or intolerant of interferon alpha and subsequently treated with imatinib show reduced immunoglobulin levels and hypogammaglobulinemia
-
Steegmann JL, Moreno G, Alaez C et al. Chronic myeloid leukemia patients resistant to or intolerant of interferon alpha and subsequently treated with imatinib show reduced immunoglobulin levels and hypogammaglobulinemia. Haematologica 2003; 88(7):762-768.
-
(2003)
Haematologica
, vol.88
, Issue.7
, pp. 762-768
-
-
Steegmann, J.L.1
Moreno, G.2
Alaez, C.3
-
25
-
-
85045797522
-
The effectiveness and cost-effectiveness of imatinib in chronic myeloid leukaemia: A systematic review
-
Garside R, Round A, Dalzell K et al. The effectiveness and cost-effectiveness of imatinib in chronic myeloid leukaemia: a systematic review. Health Technol Assess 2002; 6(33):1-162.
-
(2002)
Health Technol. Assess
, vol.6
, Issue.33
, pp. 1-162
-
-
Garside, R.1
Round, A.2
Dalzell, K.3
-
27
-
-
0037459344
-
Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL
-
Azam M, Latek RR, Daley GQ. Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL. Cell 2003; 112(6):831-843.
-
(2003)
Cell
, vol.112
, Issue.6
, pp. 831-843
-
-
Azam, M.1
Latek, R.R.2
Daley, G.Q.3
-
28
-
-
85117738646
-
Bcr-Abl mutations, resistance to imatinib, and imatinib plasma levels
-
Gambacorti-Passerini C, Piazza R, D'Incalci M. Bcr-Abl mutations, resistance to imatinib, and imatinib plasma levels. Blood 2003; 102(5):1933-1934.
-
(2003)
Blood
, vol.102
, Issue.5
, pp. 1933-1934
-
-
Gambacorti-Passerini, C.1
Piazza, R.2
D'Incalci, M.3
-
29
-
-
0037664471
-
Optimized sensitivity of allele-specific PCR for prenatal typing of human platelet alloantigen single nucleotide polymorphisms
-
Bugert P, Lese A, Meckies J, Zieger W, Eichler H, Kluter H. Optimized sensitivity of allele-specific PCR for prenatal typing of human platelet alloantigen single nucleotide polymorphisms. Biotechniques 2003; 35(1):170-174.
-
(2003)
Biotechniques
, vol.35
, Issue.1
, pp. 170-174
-
-
Bugert, P.1
Lese, A.2
Meckies, J.3
Zieger, W.4
Eichler, H.5
Kluter, H.6
-
30
-
-
0038107799
-
Comparison of two PCR-based methods and automated DNA sequencing for prop-1 genotyping in Ames dwarf mice
-
Gerstner A, DeFord JH, Papaconstantinou J. Comparison of two PCR-based methods and automated DNA sequencing for prop-1 genotyping in Ames dwarf mice. Mutat Res 2003; 528(1-2):37-44.
-
(2003)
Mutat. Res.
, vol.528
, Issue.1-2
, pp. 37-44
-
-
Gerstner, A.1
DeFord, J.H.2
Papaconstantinou, J.3
-
31
-
-
0038723184
-
Enhanced allele-specific PCR discrimination in SNP genotyping using 3′ locked nucleic acid (LNA) primers
-
Latorra D, Campbell K, Wolter A, Hurley JM. Enhanced allele-specific PCR discrimination in SNP genotyping using 3′ locked nucleic acid (LNA) primers. Hum Mutat 2003; 22(1):79-85.
-
(2003)
Hum. Mutat.
, vol.22
, Issue.1
, pp. 79-85
-
-
Latorra, D.1
Campbell, K.2
Wolter, A.3
Hurley, J.M.4
-
32
-
-
0037438467
-
Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia
-
Kantarjian HM, Talpaz M, O'Brien S et al. Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia. Blood 2003; 101(2):473-475.
-
(2003)
Blood
, vol.101
, Issue.2
, pp. 473-475
-
-
Kantarjian, H.M.1
Talpaz, M.2
O'Brien, S.3
-
33
-
-
0037309057
-
Molecular response to imatinib mesylate following relapse after allogenic SCT for CML
-
McCann SR, Gately K, Conneally E et al. Molecular response to imatinib mesylate following relapse after allogenic SCT for CML. Blood 2003; 101(3):1200-1201.
-
(2003)
Blood
, vol.101
, Issue.3
, pp. 1200-1201
-
-
McCann, S.R.1
Gately, K.2
Conneally, E.3
-
34
-
-
0037254419
-
Imatinib alone and in combination for chronic myeloid leukemia
-
Druker BJ. Imatinib alone and in combination for chronic myeloid leukemia. Semin Hematol 2003; 40(1):50-58.
-
(2003)
Semin. Hematol.
, vol.40
, Issue.1
, pp. 50-58
-
-
Druker, B.J.1
-
35
-
-
9144271748
-
In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl positive cell lines
-
La Rosee P, Johnson K, Corbin AS, Stoffregen EP, Moseson EM, Willis S, Mauro MM, Melo JV, Deininger MW, Druker BJ. In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl positive cell lines. Blood 2004; 103(1):208-215.
-
(2004)
Blood
, vol.103
, Issue.1
, pp. 208-215
-
-
La Rosee, P.1
Johnson, K.2
Corbin, A.S.3
Stoffregen, E.P.4
Moseson, E.M.5
Willis, S.6
Mauro, M.M.7
Melo, J.V.8
Deininger, M.W.9
Druker, B.J.10
-
36
-
-
0041887168
-
Results of triple therapy with interferon-alpha, cytarabine, and homoharringtonine, and the impact of adding imatinib to the treatment sequence in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in early chronic phase
-
O'Brien S, Giles F, Talpaz M et al. Results of triple therapy with interferon-alpha, cytarabine, and homoharringtonine, and the impact of adding imatinib to the treatment sequence in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in early chronic phase. Cancer 2003; 98(5):888-893.
-
(2003)
Cancer
, vol.98
, Issue.5
, pp. 888-893
-
-
O'Brien, S.1
Giles, F.2
Talpaz, M.3
-
37
-
-
0037531711
-
Advances in targeted therapy for chronic myeloid leukemia
-
Yee KW, Keating A. Advances in targeted therapy for chronic myeloid leukemia. Expert Rev Anticancer Ther 2003; 3(3):295-310.
-
(2003)
Expert. Rev. Anticancer Ther.
, vol.3
, Issue.3
, pp. 295-310
-
-
Yee, K.W.1
Keating, A.2
-
38
-
-
0037396217
-
Oblimersen sodium (G3139 Bcl-2 antisense oligonucleotide) therapy in Waldenstrom's macroglobulinemia: A targeted approach to enhance apoptosis
-
Frankel SR. Oblimersen sodium (G3139 Bcl-2 antisense oligonucleotide) therapy in Waldenstrom's macroglobulinemia: a targeted approach to enhance apoptosis. Semin Oncol 2003; 30(2):300-304.
-
(2003)
Semin. Oncol.
, vol.30
, Issue.2
, pp. 300-304
-
-
Frankel, S.R.1
-
39
-
-
0038375012
-
Several Bcr-Abl kinase domain mutants associated with imatinib mesylate resistance remain sensitive to imatinib
-
Corbin AS, Rosee PL, Stoffregen EP et al. Several Bcr-Abl kinase domain mutants associated with imatinib mesylate resistance remain sensitive to imatinib. Blood 2003; 101(11):4611-4614.
-
(2003)
Blood
, vol.101
, Issue.11
, pp. 4611-4614
-
-
Corbin, A.S.1
Rosee, P.L.2
Stoffregen, E.P.3
|