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Volumn 127, Issue 38, 2005, Pages 13164-13166

A steroid-conjugated contrast agent for magnetic resonance imaging of cell signaling

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; AZIDE; BETA GALACTOSIDASE; CONTRAST MEDIUM; COPPER IODIDE; GADOLINIUM CHELATE; ISOTHIOCYANIC ACID DERIVATIVE; MIFEPRISTONE; MIFEPRISTONE GADOLINIUM COMPLEX; OXIME; PROGESTERONE; PROGESTERONE RECEPTOR; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG;

EID: 25444516833     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja051294x     Document Type: Article
Times cited : (46)

References (27)
  • 8
    • 3042698025 scopus 로고    scopus 로고
    • Sigel, A., Sigel, H., Eds.; Marcel and Decker, Fontis Media: New York
    • Allen, M. J.; Meade, T. J. In Metal Ions in Biological Systems; Sigel, A., Sigel, H., Eds.; Marcel and Decker, Fontis Media: New York, 2004; Vol. 42, pp 1-38.
    • (2004) Metal Ions in Biological Systems , vol.42 , pp. 1-38
    • Allen, M.J.1    Meade, T.J.2
  • 23
    • 0026830935 scopus 로고
    • Compound 3 was synthesized as previously reported for a bridged steroid synthesis: Mikola, H.; Hanninen, E. Bioconjugate Chem. 1992, 3, 182-186.
    • (1992) Bioconjugate Chem. , vol.3 , pp. 182-186
    • Mikola, H.1    Hanninen, E.2
  • 24
    • 25444501394 scopus 로고    scopus 로고
    • note
    • Two different isomers (syn/anti) of 3-oxime compound were synthesized when RU-486 was refluxed with hydroxylamine hydrochloride in pyridine. The isomers were separated by column chromatography on silica using the eluent of hexane:ethyl acetate = 1:1.
  • 25
    • 25444497608 scopus 로고    scopus 로고
    • note
    • Eliminating isomerism (syn/anti at C3) may enhance the binding affinity. We attempted to separate the isomeric mixture to determine (if any) the effect that a purified isomer may have; however, we were unsuccessful.
  • 27
    • 0036741796 scopus 로고    scopus 로고
    • (b) Duffy, J. B. Genesis 2002, 34, 1-15.
    • (2002) Genesis , vol.34 , pp. 1-15
    • Duffy, J.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.