A surface plasmon resonance-based assay for small molecule inhibitors of human cyclophilin A

Analytical Biochemistry

Volumn 345, Issue 2, 2005, Pages 214-226

  Wear, Martin A ^a   Patterson, Alan ^a   Malone, Kirk ^a   Dunsmore, Colin ^a   Turner, Nicholas J ^a   Walkinshaw, Malcolm D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Competition binding assay; Cyclophilin A; Cyclosporin A; Surface plasmon resonance

Indexed keywords

AMINES; DISSOCIATION; MOLECULES; PLASMONS; RATE CONSTANTS; RESONANCE;

BINDING ASSAYS; CYCLOPHILIN A; CYCLOSPORIN A; EQUILIBRIUM DISSOCIATION CONSTANT; FLUORESCENCE TITRATIONS; KINETIC RATE CONSTANTS; NITRILOTRIACETIC ACID; SMALL MOLECULE INHIBITOR;

SURFACE PLASMON RESONANCE;

AMINE; CYCLOPHILIN A; CYCLOSPORIN A; HEXAHISTIDINE CYCLOPHILIN A; LIGAND; NICKEL; NITRILOTRIACETIC ACID; PROTEIN INHIBITOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING ASSAY; COVALENT BOND; DISSOCIATION CONSTANT; DRUG DETERMINATION; HUMAN; KINETICS; MOLECULAR SIZE; MOLECULE; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; SCREENING; SENSOR; SURFACE PLASMON RESONANCE; SURFACE PROPERTY; TIME;

EID: 25444507171     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2005.06.037     Document Type: Article

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