Improved loading and cleavage methods for solid-phase synthesis using chlorotrityl resins: Synthesis and testing of a library of 144 discrete chemicals as potential farnesyltransferase inhibitors

Journal of Combinatorial Chemistry

Volumn 6, Issue 3, 2004, Pages 407-413

  Park, Jewn Giew ^a   Langenwalter, Kevin J ^a   Weinbaum, Carolyn A ^b   Casey, Patrick J ^b   Pang, Yuan Ping ^a  

^a Mayo Clinic College of Medicine   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN FARNESYLTRANSFERASE INHIBITOR; AMINO ACID; ENZYME INHIBITOR; FARNESYL TRANS TRANSFERASE; PLANT RESIN;

ARTICLE; CHEMICAL REACTION; DECOMPOSITION; DRUG SYNTHESIS; RADIOFREQUENCY; SOLID; CHEMICAL STRUCTURE; COMBINATORIAL CHEMISTRY; SOLID PHASE SYNTHESIS;

AMINO ACIDS; COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; MOLECULAR STRUCTURE; RESINS, PLANT; SOLID-PHASE SYNTHESIS TECHNIQUES;

EID: 2542601599     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc0340729     Document Type: Article

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