Mitomycin dimers: Polyfunctional cross-linkers of DNA

Journal of Medicinal Chemistry

Volumn 47, Issue 12, 2004, Pages 3308-3319

  Paz, Manuel M ^a,c   Kumar, Gopinatha Suresh ^a,d   Glover, Mark ^b   Waring, Michael J ^b   Tomasz, Maria ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; DIMER; DNA FRAGMENT; MITOMYCIN C; MITOMYCIN DERIVATIVE; OXIDOREDUCTASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CATALYSIS; CATALYST; CPG ISLAND; DNA ADDUCT; DNA ALKYLATION; DNA CROSS LINKING; DNA DAMAGE; DNA SEQUENCE; DRUG ACTIVATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYPOXIA; MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REDUCTION; TUMOR CELL CULTURE; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CATALYSIS; CROSS-LINKING REAGENTS; DIMERIZATION; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MASS SPECTROMETRY; MICE; MICROCOCCUS LUTEUS; MITOMYCIN; MITOMYCINS; OLIGONUCLEOTIDES; OXIDATION-REDUCTION; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 2542594003     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049863j     Document Type: Article

References (41)

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