Synthesis, DNA cross-linking activity, and cytotoxicity of dimeric mitomycins

Journal of Medicinal Chemistry

Volumn 44, Issue 21, 2001, Pages 3453-3462

  Na, Y ^a   Li, V S ^a   Nakanishi, Y ^b   Bastow, K F ^b   Kohn, H ^a,b  

^a University of Houston   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DIMER; DIMERIC MITOMYCIN; DNA; MITOMYCIN; MITOMYCIN C; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DENATURING GRADIENT GEL ELECTROPHORESIS; DNA CROSS LINKING; DRUG DNA BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANTIBIOTICS, ANTINEOPLASTIC; CROSS-LINKING REAGENTS; DIMERIZATION; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTROPHORESIS, AGAR GEL; HUMANS; MITOMYCIN; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0035846075     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010090y     Document Type: Article

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