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Volumn 5, Issue 5, 2004, Pages 1117-1152

Gemifloxacin: A new fluoroquinolone

Author keywords

Fluoroquinolone; Respiratory infections; Streptococcus pneumoniae

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEPHALOSPORIN; CHLOROQUINE; CIPROFLOXACIN; CLARITHROMYCIN; CLINAFLOXACIN; COTRIMOXAZOLE; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; ENOXACIN; GATIFLOXACIN; GEMIFLOXACIN; GREPAFLOXACIN; LEVOFLOXACIN; LOMEFLOXACIN; MACROLIDE; MOXIFLOXACIN; NALIDIXIC ACID; NORFLOXACIN; PENICILLIN G; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; SUCRALFATE; TELITHROMYCIN; TETRACYCLINE; TROVAFLOXACIN; UNINDEXED DRUG;

EID: 2542560648     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.5.5.1117     Document Type: Article
Times cited : (27)

References (120)
  • 1
    • 2542596769 scopus 로고    scopus 로고
    • In vitro susceptibility of 4903 bacterial isolates of gemifloxcin - An advanced fluoroquinolone
    • BLONDEAU JM, HANSEN G, BORSOS S, IRVINE L, BLANCO L: In vitro susceptibility of 4903 bacterial isolates of gemifloxcin - an advanced fluoroquinolone. Int. J. Antimicrob. Agents (2003) 9:44-49.
    • (2003) Int. J. Antimicrob. Agents , vol.9 , pp. 44-49
    • Blondeau, J.M.1    Hansen, G.2    Borsos, S.3    Irvine, L.4    Blanco, L.5
  • 2
    • 0037229075 scopus 로고    scopus 로고
    • Mutant prevention concentration of gemifloxacin for clinical isolates of Streptococcus pneumoniae
    • HANSEN G, METZLER KL, DRLICA K, BLONDEAU JM: Mutant prevention concentration of gemifloxacin for clinical isolates of Streptococcus pneumoniae. Antimicrob. Agents Chemother. (2003) 47:440-441.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 440-441
    • Hansen, G.1    Metzler, K.L.2    Drlica, K.3    Blondeau, J.M.4
  • 4
    • 0033926264 scopus 로고    scopus 로고
    • Quinolone generations: Natural history or natural selection?
    • BALL P: Quinolone generations: natural history or natural selection? J. Antimicrob. Chemother. (2000) 46:17-24.
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 17-24
    • Ball, P.1
  • 5
    • 0028316927 scopus 로고
    • Structure-activity and structure-side-effect relationships for the quinolone antibacterials
    • DOMAGALA J: Structure-activity and structure-side-effect relationships for the quinolone antibacterials. J. Antimicrob. Chemother (1994) 33:685-706.
    • (1994) J. Antimicrob. Chemother. , vol.33 , pp. 685-706
    • Domagala, J.1
  • 6
    • 0033753211 scopus 로고    scopus 로고
    • Intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes
    • GARCIA I, PASCUAL A, BALLESTA S, JOYANES P, PEREA EJ: Intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes. Antimicrob. Agents Chemother. (2000) 44:3193-3195.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 3193-3195
    • Garcia, I.1    Pascual, A.2    Ballesta, S.3    Joyanes, P.4    Perea, E.J.5
  • 7
    • 0034534006 scopus 로고    scopus 로고
    • In vitro activity of gemifloxacin against contemporary clinical bacterial isolates from eleven North American medical centers and assessment of disk diffusion test interpretive criteria
    • FUCHS PC, BARRY AL, BROWN SD: In vitro activity of gemifloxacin against contemporary clinical bacterial isolates from eleven North American medical centers and assessment of disk diffusion test interpretive criteria. Diagn. Microbiol. Infect. Dis. (2000) 38:243-253.
    • (2000) Diagn. Microbiol. Infect. Dis. , vol.38 , pp. 243-253
    • Fuchs, P.C.1    Barry, A.L.2    Brown, S.D.3
  • 8
    • 0034087347 scopus 로고    scopus 로고
    • In vitro activity of gemifloxacin against a broad range of recent clinical isolates from the USA
    • MCCLOSKEY L MOORE T NICONOVICH N et al.: In vitro activity of gemifloxacin against a broad range of recent clinical isolates from the USA. J. Antimicrob. Chemother. (2000) 45:13-21.
    • (2000) J. Antimicrob. Chemother. , vol.45 , pp. 13-21
    • McCloskey, L.1    Moore, T.2    Niconovich, N.3
  • 10
    • 0034035396 scopus 로고    scopus 로고
    • Activity of gemifloxacin and other new quinolones against Chlamydia pneumoniae: A review
    • HAMMERSCHLAG MR: Activity of gemifloxacin and other new quinolones against Chlamydia pneumoniae: a review. J. Antimicrob. Chemother. (2000) 45:35-39.
    • (2000) J. Antimicrob. Chemother. , vol.45 , pp. 35-39
    • Hammerschlag, M.R.1
  • 11
    • 0034076785 scopus 로고    scopus 로고
    • Comparative potency of gemifloxacin, new quinolones, macrolides, tetracycline and clindamycin against Mycoplasma species
    • DUFFY LB, CRABB D, SEARCEY K et al.: Comparative potency of gemifloxacin, new quinolones, macrolides, tetracycline and clindamycin against Mycoplasma species. J. Antimicrob. Chemother. (2000) 43:29-33.
    • (2000) J. Antimicrob. Chemother. , vol.43 , pp. 29-33
    • Duffy, L.B.1    Crabb, D.2    Searcey, K.3
  • 12
    • 0034079075 scopus 로고    scopus 로고
    • Comparative in vitro activity and post-antibiotic effect of gemifloxacin against Legionella spp
    • DUBOIS J, SAINT-PIERRE C: Comparative in vitro activity and post-antibiotic effect of gemifloxacin against Legionella spp. J. Antimicrob. Chemother. (2000) 45:41-46.
    • (2000) J. Antimicrob. Chemother. , vol.45 , pp. 41-46
    • Dubois, J.1    Saint-Pierre, C.2
  • 13
    • 85069421455 scopus 로고    scopus 로고
    • In vitro activity of gemifloxacin against Helicobacter pylori
    • MINEHART HW, CHALKER AF: In vitro activity of gemifloxacin against Helicobacter pylori. J. Antimicrob. Chemother. (2001) 47:357-368.
    • (2001) J. Antimicrob. Chemother. , vol.47 , pp. 356-357
    • Minehart, H.W.1    Chalker, A.F.2
  • 14
    • 0034110572 scopus 로고    scopus 로고
    • In vitro activity of gemifloxacin and other antimicrobial agents against isolates of Bordetella pertussis and Bordetella parapertussis
    • MORTENSEN JE, RODGERS GL: In vitro activity of gemifloxacin and other antimicrobial agents against isolates of Bordetella pertussis and Bordetella parapertussis. J. Antimicrob. Chemother. (2000) 45:47-49.
    • (2000) J. Antimicrob. Chemother. , vol.45 , pp. 47-49
    • Mortensen, J.E.1    Rodgers, G.L.2
  • 15
    • 0034119084 scopus 로고    scopus 로고
    • Bactericidal activity of gemifloxacin and other quinolones against Streptococcus pneumoniae
    • MORRISSEY I, GEORGE JT. Bactericidal activity of gemifloxacin and other quinolones against Streptococcus pneumoniae. J. Antimicrob. Chemother. (2000) 45:107-110.
    • (2000) J. Antimicrob. Chemother. , vol.45 , pp. 107-110
    • Morrissey, I.1    George, J.T.2
  • 16
    • 0037507217 scopus 로고    scopus 로고
    • Inhibitory and bactericidal activities of gemifloxacin and other antimicrobial against Mycoplasma pneumoniae
    • WAITES KB, CRABB DM, DUFFY LB: Inhibitory and bactericidal activities of gemifloxacin and other antimicrobial against Mycoplasma pneumoniae. Int. J. Antimicrob. Agents (2003) 21:574-577.
    • (2003) Int. J. Antimicrob. Agents , vol.21 , pp. 574-577
    • Waites, K.B.1    Crabb, D.M.2    Duffy, L.B.3
  • 17
    • 0034119081 scopus 로고    scopus 로고
    • Bactericidal and bacteriostatic activity of gemifloxacin against Acinetobacter spp. in vitro
    • HIGGINS PG, COLEMAN K, AMYES SGB: Bactericidal and bacteriostatic activity of gemifloxacin against Acinetobacter spp. in vitro. J. Antimicrob. Chemother. (2000) 45(Suppl. 1):71-77.
    • (2000) J. Antimicrob. Chemother. , vol.45 , Issue.SUPPL. 1 , pp. 71-77
    • Higgins, P.G.1    Coleman, K.2    Amyes, S.G.B.3
  • 18
    • 0003311049 scopus 로고    scopus 로고
    • Post-antibiotic effect (PAE) of gemifloxacin (SP-265805) and ciprofloxacin against Gram-positive and Gram-negative organisms
    • San Francisco, CA, USA
    • MOORE T, KERSHNER K, DONALD B et al.: Post-antibiotic effect (PAE) of gemifloxacin (SP-265805) and ciprofloxacin against Gram-positive and Gram-negative organisms. Paper presented at the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, CA, USA (1999).
    • (1999) The 39th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Moore, T.1    Kershner, K.2    Donald, B.3
  • 19
    • 0013669779 scopus 로고    scopus 로고
    • Post-antibiotic effect (PAE) of gemifloxacin (SB-265805) in S. pneumoniae with diminished susceptibility to ciprofloxacin
    • San Francisco, CA, USA
    • MACKENZIE H, FORWARD K, DE AZAVEDO J et al.: Post-antibiotic effect (PAE) of gemifloxacin (SB-265805) in S. pneumoniae with diminished susceptibility to ciprofloxacin. Paper presented at the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, CA, USA (1999).
    • (1999) The 39th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • MacKenzie, H.1    Forward, K.2    De Azavedo, J.3
  • 20
    • 0033867094 scopus 로고    scopus 로고
    • The effect of ferrous sulphate and sucralfate on the bioavailability of oral gemifloxacin in healthy volunteers
    • ALLEN A, BYGATE E, FAESSEL H, ISAAC L, LEWIS A: The effect of ferrous sulphate and sucralfate on the bioavailability of oral gemifloxacin in healthy volunteers. Inte. J. Antimicrob. Agents (2000) 15:283-289.
    • (2000) Inte. J. Antimicrob. Agents , vol.15 , pp. 283-289
    • Allen, A.1    Bygate, E.2    Faessel, H.3    Isaac, L.4    Lewis, A.5
  • 21
    • 0034118232 scopus 로고    scopus 로고
    • Pharmacokinetics and tolerability of gemifloxacin (SB-265805) after administration of single oral doses to healthy volunteers
    • ALLEN A, BYGATE E, OLIVER S, JOHNSON M, WARD C, CHEON A-J, CHOO YS, KIM IC: Pharmacokinetics and tolerability of gemifloxacin (SB-265805) after administration of single oral doses to healthy volunteers. Antimicrob. Agents Chemother. (2000) 44:1604-1608.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1604-1608
    • Allen, A.1    Bygate, E.2    Oliver, S.3    Johnson, M.4    Ward, C.5    Cheon, A.-J.6    Choo, Y.S.7    Kim, I.C.8
  • 22
    • 0000853149 scopus 로고    scopus 로고
    • Pharmacokinetics of LB20304, a new fluoroquinolone in rats and dogs
    • SEO SM, LEE SH, CHOI YJ et al.: Pharmacokinetics of LB20304, a new fluoroquinolone in rats and dogs. Arch. Pharm. Res. (1996) 19:359-367.
    • (1996) Arch. Pharm. Res. , vol.19 , pp. 359-367
    • Seo, S.M.1    Lee, S.H.2    Choi, Y.J.3
  • 24
    • 0012740212 scopus 로고    scopus 로고
    • The relationship between the mutant prevention concentration (MPC) of fluoroquinolones (FQ) against Streptococcus pneumoniae (SP) and the 24-hour dose-response curves
    • Edinburgh, Scotland, UK
    • BLONDEAU JM, DRLICA K, HANSEN G, ZHAO X: The relationship between the mutant prevention concentration (MPC) of fluoroquinolones (FQ) against Streptococcus pneumoniae (SP) and the 24-hour dose-response curves. Paper presented at the 7th International Symposium of New Quinolones, Edinburgh, Scotland, UK (2001).
    • (2001) The 7th International Symposium of New Quinolones
    • Blondeau, J.M.1    Drlica, K.2    Hansen, G.3    Zhao, X.4
  • 25
    • 0034969096 scopus 로고    scopus 로고
    • Comparative in vitro activity of gemifloxacin, ciprofloxacin, levofloxacin and ofloxacin in a North American surveillance study
    • Gemifloxacin Surveillance Study Research Group:
    • HOBAN DJ, BOUCHILLON SK, JOHNSON JL et al.: Gemifloxacin Surveillance Study Research Group: Comparative in vitro activity of gemifloxacin, ciprofloxacin, levofloxacin and ofloxacin in a North American surveillance study. Diagn. Microbiol. Infect. Dis. (2001) 40:51-57.
    • (2001) Diagn. Microbiol. Infect. Dis. , vol.40 , pp. 51-57
    • Hoban, D.J.1    Bouchillon, S.K.2    Johnson, J.L.3
  • 26
    • 0035142088 scopus 로고    scopus 로고
    • Multiple-dose pharmacokinetics and tolerability of gemifloxacin administered orally to healthy volunteers
    • ALLEN A BYGATE E VOUSDEN M et al.: Multiple-dose pharmacokinetics and tolerability of gemifloxacin administered orally to healthy volunteers. Antimicrob. Agents Chemother. (2001) 45:540-545.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 540-545
    • Allen, A.1    Bygate, E.2    Vousden, M.3
  • 27
    • 0035050988 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue penetration of gemifloxacin following a single oral dose
    • GEE T, ANDREWS JM, ASHBY JP, MARSHALL G, WISE R: Pharmacokinetics and tissue penetration of gemifloxacin following a single oral dose. J. Chemother. (2001) 47:431-434.
    • (2001) J. Chemother. , vol.47 , pp. 431-434
    • Gee, T.1    Andrews, J.M.2    Ashby, J.P.3    Marshall, G.4    Wise, R.5
  • 28
    • 0032711950 scopus 로고    scopus 로고
    • Lack of effect of gemifloxacin on the steady-state pharmacodynamics of warfarin in healthy volunteers
    • DAVY M, BIRD N, ROST KL, FUDER H: Lack of effect of gemifloxacin on the steady-state pharmacodynamics of warfarin in healthy volunteers. Chemotherapy (1999) 45:491-495.
    • (1999) Chemotherapy , vol.45 , pp. 491-495
    • Davy, M.1    Bird, N.2    Rost, K.L.3    Fuder, H.4
  • 29
    • 0032737922 scopus 로고    scopus 로고
    • Lack of pharmacokinetic interaction between gemifloxacin and digoxin in healthy elderly volunteers
    • VOUSDEN M, ALLEN A, LEWIS A et al.: Lack of pharmacokinetic interaction between gemifloxacin and digoxin in healthy elderly volunteers. Chemotherapy Basel (1999) 45:485-490.
    • (1999) Chemotherapy Basel , vol.45 , pp. 485-490
    • Vousden, M.1    Allen, A.2    Lewis, A.3
  • 30
    • 0032736884 scopus 로고    scopus 로고
    • Lack of effect of gemifloxacin on the steady-state pharmacokinetics of theophylline in healthy volunteers
    • DAVY M, ALLEN A, BIRD N, ROST KL, FUDER H: Lack of effect of gemifloxacin on the steady-state pharmacokinetics of theophylline in healthy volunteers. Chemotherapy (1999) 45:478-484.
    • (1999) Chemotherapy , vol.45 , pp. 478-484
    • Davy, M.1    Allen, A.2    Bird, N.3    Rost, K.L.4    Fuder, H.5
  • 33
    • 0034922168 scopus 로고    scopus 로고
    • In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and its pharmacokinetics in guinea pigs with L. pneumophila pneumonia
    • EDELSTEIN PH, SHINZATO T, DOYLE E, EDELSTEIN MA: In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and its pharmacokinetics in guinea pigs with L. pneumophila pneumonia. Antimicrob. Agents Chemother. (2001) 45:2204-2209.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 2204-2209
    • Edelstein, P.H.1    Shinzato, T.2    Doyle, E.3    Edelstein, M.A.4
  • 34
    • 0036239817 scopus 로고    scopus 로고
    • Gemifloxacin is efficacious against penicillin-resistant and quinolone-resistant pneumococci in experimental meningitis
    • COTTAGNOUD P, ACOSTA F, COTTAGNOUD M, TAUBER MG: Gemifloxacin is efficacious against penicillin-resistant and quinolone-resistant pneumococci in experimental meningitis. Antimicrob. Agents Chemother. (2002) 46:1607-1609.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 1607-1609
    • Cottagnoud, P.1    Acosta, F.2    Cottagnoud, M.3    Tauber, M.G.4
  • 37
    • 0035139529 scopus 로고    scopus 로고
    • Effects of single oral doses of gemifloxacin (320 milligrams) versus trovafloxacin (200 milligrams) on fecal flora ini healthy volunteers
    • GARCIA-CALVO G, MOLLEJA A, GIMENEZ MJ et al.: Effects of single oral doses of gemifloxacin (320 milligrams) versus trovafloxacin (200 milligrams) on fecal flora ini healthy volunteers. Antimicrob. Agents Chemother. (2001) 45:608-611.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 608-611
    • Garcia-Calvo, G.1    Molleja, A.2    Gimenez, M.J.3
  • 38
    • 2542555607 scopus 로고    scopus 로고
    • Effect of gemifloxacin and comparator quinolones on the development of in vitro bacterial resistance
    • Birmingham, UK
    • RITTENHAUSE S, DONALD B, NICONOVICH N et al.: Effect of gemifloxacin and comparator quinolones on the development of in vitro bacterial resistance. Paper presented at the 21st International Congress of Chemotherapy, Birmingham, UK (1999).
    • (1999) The 21st International Congress of Chemotherapy
    • Rittenhause, S.1    Donald, B.2    Niconovich, N.3
  • 39
    • 0032803964 scopus 로고    scopus 로고
    • Effect of fluoroquinolone concentration on selection of resistant mutants of Mycobacterium bovis BCG and Staphylococcus aureus
    • DONG Y, ZHAO X, DOMAGALA J, DRLICA K: Effect of fluoroquinolone concentration on selection of resistant mutants of Mycobacterium bovis BCG and Staphylococcus aureus. Antimicrob. Agents Chemother. (1999) 43:1756-1758.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 1756-1758
    • Dong, Y.1    Zhao, X.2    Domagala, J.3    Drlica, K.4
  • 40
    • 0346025671 scopus 로고    scopus 로고
    • Antimicrobial susceptibility among community-acquired respiratory tract pathogens in the USA: Data from PROTEKT US 2000-01
    • DOERN GV, BROWN SD: Antimicrobial susceptibility among community-acquired respiratory tract pathogens in the USA: data from PROTEKT US 2000-01. J. Infect. (2004) 48:56-65.
    • (2004) J. Infect. , vol.48 , pp. 56-65
    • Doern, G.V.1    Brown, S.D.2
  • 41
    • 0034999522 scopus 로고    scopus 로고
    • Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000, including a comparison of resistance rates since 1994-1995
    • DOERN GV, HEILMANN KP, HUYNH HK, RHOMBERG PR, COFFMAN SL, BRUEGGEMANN AB: Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000, including a comparison of resistance rates since 1994-1995. Antimicrob. Agents Chemother. (2001) 45:1721-1729.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1721-1729
    • Doern, G.V.1    Heilmann, K.P.2    Huynh, H.K.3    Rhomberg, P.R.4    Coffman, S.L.5    Brueggemann, A.B.6
  • 42
    • 0036265885 scopus 로고    scopus 로고
    • Evolving resistance patterns in community-acquired respiratory tract pathogens: First results from the PROTEKT global surveillance study
    • FELMINGHAM D: Evolving resistance patterns in community-acquired respiratory tract pathogens: first results from the PROTEKT global surveillance study. J. Infect. (2002) 44:3-10.
    • (2002) J. Infect. , vol.44 , pp. 3-10
    • Felmingham, D.1
  • 43
    • 0346656808 scopus 로고    scopus 로고
    • Antibacterial resistance among children with community-acquired respiratory tract infections (PROTEKT 1999-2000)
    • FELMINGHAM D, FARRELL DJ, REINERT R, RENE, MORRISSEY I: Antibacterial resistance among children with community-acquired respiratory tract infections (PROTEKT 1999-2000). J. Infect. (2004) 48:39-55.
    • (2004) J. Infect. , vol.48 , pp. 39-55
    • Felmingham, D.1    Farrell, D.J.2    Reinert, R.3    Rene, A.4    Morrissey, I.5
  • 44
    • 0032979046 scopus 로고    scopus 로고
    • Spread of drug-resistant Streptococcus pneumoniae in Asian countries: Asian Network for Surveillance of Resistant Pathogens (ANSORP) Study
    • SONG JH LEE NY ICHIYAMA S et al.: Spread of drug-resistant Streptococcus pneumoniae in Asian countries: Asian Network for Surveillance of Resistant Pathogens (ANSORP) Study. Clin. Infect. Dis. (1999) 28:1206-1211.
    • (1999) Clin. Infect. Dis. , vol.28 , pp. 1206-1211
    • Song, J.H.1    Lee, N.Y.2    Ichiyama, S.3
  • 45
    • 0032898031 scopus 로고    scopus 로고
    • A review of the comparative in vitro activity of 12 antimicrobial agents with a focus on 4 new 'respiratory quinolones'
    • BLONDEAU JM: A review of the comparative in vitro activity of 12 antimicrobial agents with a focus on 4 new 'respiratory quinolones'. J. Antimicrob. Chemother. (1999) 43:1-11.
    • (1999) J. Antimicrob. Chemother. , vol.43 , pp. 1-11
    • Blondeau, J.M.1
  • 46
    • 0035884888 scopus 로고    scopus 로고
    • Antimicrobial use and the emergence of antimicrobial resistance with Streptococcus pneumoniae in the United States
    • DOERN GV: Antimicrobial use and the emergence of antimicrobial resistance with Streptococcus pneumoniae in the United States. Clin. Infect. Dis. (2001) 33:S187-S192.
    • (2001) Clin. Infect. Dis. , vol.33
    • Doern, G.V.1
  • 47
    • 0034102552 scopus 로고    scopus 로고
    • Epidemiology of respiratory tract infections
    • HOFFKEN G: Epidemiology of respiratory tract infections. European Respiratory Review (2000) 10:149-155.
    • (2000) European Respiratory Review , vol.10 , pp. 149-155
    • Hoffken, G.1
  • 48
    • 0035001923 scopus 로고    scopus 로고
    • Linezolid - A review of the first oxazolidinone
    • NORRBY R: Linezolid - a review of the first oxazolidinone. Expert Opin. Pharmacother. (2001) 2:293-302.
    • (2001) Expert Opin. Pharmacother. , vol.2 , pp. 293-302
    • Norrby, R.1
  • 49
    • 0033595136 scopus 로고    scopus 로고
    • Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada
    • CHEN DK, MCGEER A, DE AZAVED0 J, LOW DE: Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada. New Engl. J. Med. (1999) 341:233-239.
    • (1999) New Engl. J. Med. , vol.341 , pp. 233-239
    • Chen, D.K.1    Mcgeer, A.2    De Azavedo, J.3    Low, D.E.4
  • 50
    • 0035189079 scopus 로고    scopus 로고
    • Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: Results of a Hong Kong multicenter study in 2000
    • HO PL, YUNG RWH, TSANG DN, QUE TL, HO M, SETO WH: Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: results of a Hong Kong multicenter study in 2000. J. Antimicrob. Chemother. (2001) 48:659-665.
    • (2001) J. Antimicrob. Chemother. , vol.48 , pp. 659-665
    • Ho, P.L.1    Yung, R.W.H.2    Tsang, D.N.3    Que, T.L.4    Ho, M.5    Seto, W.H.6
  • 51
    • 0032908242 scopus 로고    scopus 로고
    • Emergence of fluoroquinolone resistance among multiple resistant strains of Streptococcus pneumoniae in Hong Kong
    • HO PL, QUE TL, TSANG DN, NG TK, CHOW KH, SETO WH: Emergence of fluoroquinolone resistance among multiple resistant strains of Streptococcus pneumoniae in Hong Kong. Antimicrob. Agents Chemother. (1999) 43:1310-1313.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 1310-1313
    • Ho, P.L.1    Que, T.L.2    Tsang, D.N.3    Ng, T.K.4    Chow, K.H.5    Seto, W.H.6
  • 52
    • 0033963629 scopus 로고    scopus 로고
    • A review of clinical trials with fluoroquinolones with an emphasis on new agents
    • BLONDEAU JM: A review of clinical trials with fluoroquinolones with an emphasis on new agents. Expert Opin. Investig. Drugs (2000) 9:383-413.
    • (2000) Expert Opin. Investig. Drugs , vol.9 , pp. 383-413
    • Blondeau, J.M.1
  • 53
    • 0033744515 scopus 로고    scopus 로고
    • Potent antipneumococcal activity of gemifloxacin is associated with dual targeting of gyrase and topoisomerase IV, an in vivo target preference for gyrase, and enhanced stabilization of cleavable complexes in vitro
    • HEATON VJ, AMBLER J, FISHER LM: Potent antipneumococcal activity of gemifloxacin is associated with dual targeting of gyrase and topoisomerase IV, an in vivo target preference for gyrase, and enhanced stabilization of cleavable complexes in vitro. Antimicrob. Agents Chemother. (2000) 44:3112-3117.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 3112-3117
    • Heaton, V.J.1    Ambler, J.2    Fisher, L.M.3
  • 54
    • 0033081949 scopus 로고    scopus 로고
    • Mechanisms of fluoroquinolone resistance
    • HOOPER DC: Mechanisms of fluoroquinolone resistance. Drug Resistance Updates (1999) 2:38-55.
    • (1999) Drug Resistance Updates , vol.2 , pp. 38-55
    • Hooper, D.C.1
  • 55
    • 0035992115 scopus 로고    scopus 로고
    • Dual activity of fluoroquinolones against Streptococcus pneumoniae: The facts behind the claims
    • SMITH HJ, NICHOL KA, HOBAN DJ, ZHANEL GG: Dual activity of fluoroquinolones against Streptococcus pneumoniae: the facts behind the claims. J. Antimicrob. Chemother. (2002) 49:893-895.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 893-895
    • Smith, H.J.1    Nichol, K.A.2    Hoban, D.J.3    Zhanel, G.G.4
  • 57
    • 0037323758 scopus 로고    scopus 로고
    • Dual activity of fluoroquinolones against Streptococcus pneumoniae
    • FISHER LM, HEATON VJ: Dual activity of fluoroquinolones against Streptococcus pneumoniae. J. Antimicrob. Chemother. (2003) 51:463-464.
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 463-464
    • Fisher, L.M.1    Heaton, V.J.2
  • 58
    • 0037323758 scopus 로고    scopus 로고
    • Dual activity of fluoroquinolones against Streptococcus pneumoniae: Reply
    • SMITH H, NICHOL KA, HOBAN DJ et al.: Dual activity of fluoroquinolones against Streptococcus pneumoniae: reply. J. Antimicrob. Chemother. (2003) 51:464-465.
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 464-465
    • Smith, H.1    Nichol, K.A.2    Hoban, D.J.3
  • 59
    • 0035139520 scopus 로고    scopus 로고
    • Mutant prevention concentration of fluoroquinolones for clinical isolates of Streptococcus pneumoniae
    • BLONDEAU JM, ZHAO X, HANSEN G, DRLICA K: Mutant prevention concentration of fluoroquinolones for clinical isolates of Streptococcus pneumoniae. Antimicrob. Agents Chemother. (2001) 45:433-438.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 433-438
    • Blondeau, J.M.1    Zhao, X.2    Hansen, G.3    Drlica, K.4
  • 60
    • 0035023593 scopus 로고    scopus 로고
    • Contributions of the 8-methoxy group of gatifloxacin to resistance selectivity, target peference and antibacterial activity against Streptococcus pneumonaie
    • FUKUDA H, KISHII R, TAKEI M et al.: Contributions of the 8-methoxy group of gatifloxacin to resistance selectivity, target peference and antibacterial activity against Streptococcus pneumonaie. Antimicrob. Agents Chemother. (2001) 45:1649-1653.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1649-1653
    • Fukuda, H.1    Kishii, R.2    Takei, M.3
  • 61
    • 0037224133 scopus 로고    scopus 로고
    • Contribution of the 8-methoxy group to the activity of gatifloxacin against Type II topoisomerase of Streptococcus pneumoniae
    • KISHII R, TAKEI M, FUKUDA H, HAYASHI K, HOSAKA M: Contribution of the 8-methoxy group to the activity of gatifloxacin against Type II topoisomerase of Streptococcus pneumoniae. Antimicrob. Agents Chemother. (2003) 47:77-81.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 77-81
    • Kishii, R.1    Takei, M.2    Fukuda, H.3    Hayashi, K.4    Hosaka, M.5
  • 62
    • 0034017776 scopus 로고    scopus 로고
    • Intracellular targets of moxifloxacin: A comparison with other quinolones
    • PESTOVA E, MILLICHAP JJ, NOSKIN GA et al.: Intracellular targets of moxifloxacin: a comparison with other quinolones. J. Antimicrob. Chemother. (2000) 45:583-590.
    • (2000) J. Antimicrob. Chemother. , vol.45 , pp. 583-590
    • Pestova, E.1    Millichap, J.J.2    Noskin, G.A.3
  • 63
    • 0031784975 scopus 로고    scopus 로고
    • DNA gyrase and topoisomerase IV are dual targets of clinafloxacin action in Streptococcus pneumoniae
    • PAN X, FISHER LM: DNA gyrase and topoisomerase IV are dual targets of clinafloxacin action in Streptococcus pneumoniae. Antimicrob. Agents Chemother. (1998) 42:2810-2816.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 2810-2816
    • Pan, X.1    Fisher, L.M.2
  • 64
    • 0031046694 scopus 로고    scopus 로고
    • Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: Selective targeting of gyrase or topoisomerase IV by quinolones
    • PAN X, FISHER ML: Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: Selective targeting of gyrase or topoisomerase IV by quinolones. Antimicrob. Agents Chemother. (1997) 41:471-474.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 471-474
    • Pan, X.1    Fisher, M.L.2
  • 65
    • 0033029687 scopus 로고    scopus 로고
    • Primary targets of fluoroquinolones in Streptococcus pneumoniae
    • FUKUDA H, HIRAMATSU K: Primary targets of fluoroquinolones in Streptococcus pneumoniae. Antimicrob. Agents Chemother. (1999) 43:410-412.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 410-412
    • Fukuda, H.1    Hiramatsu, K.2
  • 66
    • 0029834825 scopus 로고    scopus 로고
    • Activity of the new fluoroquinolone trovafloxacin (CP-99,219) against DNA gyrase and topopisomerase IV mutants of Streptococcus pneumoniae
    • GOOTZ TD ZANIEWSKI L HASKELL S et al.: Activity of the new fluoroquinolone trovafloxacin (CP-99,219) against DNA gyrase and topopisomerase IV mutants of Streptococcus pneumoniae. Antimicrob. Agents Chemother. (1996) 40:2691-2697.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 2691-2697
    • Gootz, T.D.1    Zaniewski, L.2    Haskell, S.3
  • 67
    • 0029852080 scopus 로고    scopus 로고
    • High level fluoroquinolone resistance in Streptococcus pneumoniae require mutations in parC and gyrA
    • JANOIR C, KELLER V, KITZIS MD, MOREAU NJ, GUTMANN L: High level fluoroquinolone resistance in Streptococcus pneumoniae require mutations in parC and gyrA. Antimicrob. Agents Chemother. (1996) 40:2760-2764.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 2760-2764
    • Janoir, C.1    Keller, V.2    Kitzis, M.D.3    Moreau, N.J.4    Gutmann, L.5
  • 68
    • 0029846117 scopus 로고    scopus 로고
    • ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyraseA subunit in forming resistant phenotype
    • MUNOZ R, DE LA CAMPA AG: ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyraseA subunit in forming resistant phenotype. Antimicrob. Agents Chemother. (1997) 40:2252-2257.
    • (1997) Antimicrob. Agents Chemother. , vol.40 , pp. 2252-2257
    • Munoz, R.1    De La Campa, A.G.2
  • 69
    • 0029794181 scopus 로고    scopus 로고
    • Involvement of topoisomerase IV and DNA gyrase as ciprofloxacin targets in Streptococcus pneumoniae
    • PAN X, AMBLER J, MEHTAR S, FISHER LM: Involvement of topoisomerase IV and DNA gyrase as ciprofloxacin targets in Streptococcus pneumoniae. Antimicrob. Agents Chemother. (1996) 40:2321-2326.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 2321-2326
    • Pan, X.1    Ambler, J.2    Mehtar, S.3    Fisher, L.M.4
  • 70
    • 8944237982 scopus 로고    scopus 로고
    • Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: Role in fluoroquinolone resistance
    • PAN XS, FISHER LM: Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance. J. Bacteriol. (1996) 178:4060-4069.
    • (1996) J. Bacteriol. , vol.178 , pp. 4060-4069
    • Pan, X.S.1    Fisher, L.M.2
  • 71
    • 0030956604 scopus 로고    scopus 로고
    • Characterization of a mutation in the parE gene that confers fluoroquinolone resistance in Streptococcus pneumoniae
    • PERICHON B, TANKOVIC J, COURVALIN P: Characterization of a mutation in the parE gene that confers fluoroquinolone resistance in Streptococcus pneumoniae. Antimicrob. Agents Chemother. (1997) 41:1166-1167.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1166-1167
    • Perichon, B.1    Tankovic, J.2    Courvalin, P.3
  • 72
    • 0029911379 scopus 로고    scopus 로고
    • Contribution of mutations in the gyrA and parC genes to fluoroquinolone resistance of mutants of Streptococcus pneumoniae obtained in vivo and in vitro
    • TANKOVIC J, PERICHON B, DUVAL J, COURVALIN P: Contribution of mutations in the gyrA and parC genes to fluoroquinolone resistance of mutants of Streptococcus pneumoniae obtained in vivo and in vitro. Antimicrob. Agents Chemother. (1996) 40:2502-2510.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 2502-2510
    • Tankovic, J.1    Perichon, B.2    Duval, J.3    Courvalin, P.4
  • 73
    • 0033979885 scopus 로고    scopus 로고
    • Engineering the specificity of antibacterial fluoroquinolones: Benzenesulfonamide modifications at C-7 of ciprofloxacin change its primary target in Streptococcus pneumoniae from topoisomerase IV to gyrase
    • ALOVERO FL, PAN X, MORRIS JE, MANZO RH, FISHER LM: Engineering the specificity of antibacterial fluoroquinolones: benzenesulfonamide modifications at C-7 of ciprofloxacin change its primary target in Streptococcus pneumoniae from topoisomerase IV to gyrase. Antimicrob. Agents Chemother. (2000) 44:320-325.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 320-325
    • Alovero, F.L.1    Pan, X.2    Morris, J.E.3    Manzo, R.H.4    Fisher, L.M.5
  • 75
    • 0017293334 scopus 로고
    • Concentrations of bacteria in cerebrospinal fluid of patients with bacterial meningitis
    • FELDMAN W: Concentrations of bacteria in cerebrospinal fluid of patients with bacterial meningitis. J. Pediatr. (1976) 88:549-552.
    • (1976) J. Pediatr. , vol.88 , pp. 549-552
    • Feldman, W.1
  • 76
    • 0021350213 scopus 로고
    • Drug resistance in mycobacteria
    • MITCHISON DA: Drug resistance in mycobacteria. Br. J. Bull. (1984) 50:84-90.
    • (1984) Br. J. Bull. , vol.50 , pp. 84-90
    • Mitchison, D.A.1
  • 79
    • 0036861678 scopus 로고    scopus 로고
    • Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalized with community-acquired pneumonia: A randomized, open-label, multicenter study of clinical efficacy and tolerability
    • the 185 Gemifloxacin Study Group
    • LODE H, FILE TM Jr, MANDELL LA, BALL P, PYPSTRA R, THOMAS M and the 185 GEMIFLOXACIN STUDY GROUP: Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalized with community-acquired pneumonia: a randomized, open-label, multicenter study of clinical efficacy and tolerability. Clin. Ther. (2002) 24:1915-1936.
    • (2002) Clin. Ther. , vol.24 , pp. 1915-1936
    • Lode, H.1    File Jr., T.M.2    Mandell, L.A.3    Ball, P.4    Pypstra, R.5    Thomas, M.6
  • 80
    • 0036255914 scopus 로고    scopus 로고
    • A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes
    • the 068 Study Group
    • WILSON R, SCHENTAG JJ, BALL P, MANDELL LA and the 068 STUDY GROUP: A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes. Clin. Ther. (2002) 24:639-652.
    • (2002) Clin. Ther. , vol.24 , pp. 639-652
    • Wilson, R.1    Schentag, J.J.2    Ball, P.3    Mandell, L.A.4
  • 81
    • 0034901332 scopus 로고    scopus 로고
    • Efficacy and safety of gemifloxacin 320 mg once-daily for 7 days in the treatment of adult lower respiratory tract infections
    • the 061 Study Group
    • BALL P, FILE TM Jr, TWYNHOLM M, HENKEL T and the 061 STUDY GROUP: Efficacy and safety of gemifloxacin 320 mg once-daily for 7 days in the treatment of adult lower respiratory tract infections. Int. J. Antimicrob. Agents (2001) 18:19-27.
    • (2001) Int. J. Antimicrob. Agents , vol.18 , pp. 19-27
    • Ball, P.1    File Jr., T.M.2    Twynholm, M.3    Henkel, T.4
  • 82
    • 0034916311 scopus 로고    scopus 로고
    • Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: A randomized, double-blind comparison with trovafloxacin
    • the 049 Clinical Study Group
    • FILE TM Jr, SCHLEMMER B, GARAU J, CUPO M, YOUNG C and the 049 CLINICAL STUDY GROUP: Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: a randomized, double-blind comparison with trovafloxacin. J. Antimicrob. Chemother. (2001) 48:67-74.
    • (2001) J. Antimicrob. Chemother. , vol.48 , pp. 67-74
    • File Jr., T.M.1    Schlemmer, B.2    Garau, J.3    Cupo, M.4    Young, C.5
  • 83
    • 0033547373 scopus 로고    scopus 로고
    • Fluoroquinolone resistance in Streptococcus pneumonaie
    • LINARES J, DE LA CAMPA AG, PALLARES R: Fluoroquinolone resistance in Streptococcus pneumonaie. New Eng. J. Med. (1999) 341:1546-1547.
    • (1999) New Eng. J. Med. , vol.341 , pp. 1546-1547
    • Linares, J.1    De La Campa, A.G.2    Pallares, R.3
  • 84
    • 0032856370 scopus 로고    scopus 로고
    • Mechanism of fluoroquinolone action
    • DRLICA K: Mechanism of fluoroquinolone action. Curr. Opin. Microbiol. (1999) 2:504-508.
    • (1999) Curr. Opin. Microbiol. , vol.2 , pp. 504-508
    • Drlica, K.1
  • 87
    • 0032730502 scopus 로고    scopus 로고
    • Evaluation of phototoxic potential of gemifloxacin in healthy volunteers compared with ciprofloxacin
    • VOUSDEN M, FERGUSON J, RICHARDS JG et al.: Evaluation of phototoxic potential of gemifloxacin in healthy volunteers compared with ciprofloxacin. Chemotherapy Basel (1999) 45:512-520.
    • (1999) Chemotherapy Basel , vol.45 , pp. 512-520
    • Vousden, M.1    Ferguson, J.2    Richards, J.G.3
  • 88
    • 0242362709 scopus 로고    scopus 로고
    • A profile of gemifloxacin, a new respiratory fluoroquinolone
    • FILE TM Jr, IANNINI PB: A profile of gemifloxacin, a new respiratory fluoroquinolone. Today's Therapeutic Trends (2003) 21:415-435.
    • (2003) Today's Therapeutic Trends , vol.21 , pp. 415-435
    • File Jr., T.M.1    Iannini, P.B.2
  • 89
    • 0033869866 scopus 로고    scopus 로고
    • Gatifloxacin: A new fluoroquinolone
    • BLONDEAU JM: Gatifloxacin: a new fluoroquinolone. Expert Opin. Investig. Drugs (2000) 9:1877-1895.
    • (2000) Expert Opin. Investig. Drugs , vol.9 , pp. 1877-1895
    • Blondeau, J.M.1
  • 90
    • 0035002921 scopus 로고    scopus 로고
    • Moxifloxacin: A review of the microbiological, pharmacological, clinical and safety features
    • BLONDEAU JM, HANSEN G: Moxifloxacin: a review of the microbiological, pharmacological, clinical and safety features. Expert Opin. Pharmacother. (2001) 2:317-335.
    • (2001) Expert Opin. Pharmacother. , vol.2 , pp. 317-335
    • Blondeau, J.M.1    Hansen, G.2
  • 91
    • 0033910453 scopus 로고    scopus 로고
    • Gemifloxacin: Survival of the fittest
    • MANDELL LA: Gemifloxacin: survival of the fittest. J. Antimicrob. Chemother. (2000) 46:33-37.
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 33-37
    • Mandell, L.A.1
  • 92
    • 0038441385 scopus 로고    scopus 로고
    • Susceptibilities of levofloxacin in Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis clinical isolates from children: Results from 2000-2001 and 2001-2002 TRUST studies in the United States
    • KARLOWSKY JA THORNSBERRY C CRITCHLEY IA et al.: Susceptibilities of levofloxacin in Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis clinical isolates from children: results from 2000-2001 and 2001-2002 TRUST studies in the United States. Antimicrob. Agents Chemother. (2003) 47:1790-1797.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1790-1797
    • Karlowsky, J.A.1    Thornsberry, C.2    Critchley, I.A.3
  • 93
    • 0036499123 scopus 로고    scopus 로고
    • Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in the United States: Results from the TRUST surveillance program, 1999-2000
    • THORNSBERRY C, SAHM DF, KELLY LJ et al.: Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in the United States: results from the TRUST surveillance program, 1999-2000. Clin. Infect. Dis. (2002) 34:S4-S16.
    • (2002) Clin. Infect. Dis. , vol.34
    • Thornsberry, C.1    Sahm, D.F.2    Kelly, L.J.3
  • 94
    • 0036242204 scopus 로고    scopus 로고
    • Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in Canada during 2000
    • LOW DE, DE AZAVEDO J, WEISS K et al.: Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in Canada during 2000. Antimicrob. Agents Chemother. (2002) 46:1295-1301.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 1295-1301
    • Low, D.E.1    De Azavedo, J.2    Weiss, K.3
  • 95
    • 0038441345 scopus 로고    scopus 로고
    • Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: Results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002
    • ZHANEL GG, PALATNICK L, NICHOL KA, BELLYOU T, LOW DE, HOBAN DJ: Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002. Antimicrob. Agents Chemother. (2003) 47:1867-1874.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1867-1874
    • Zhanel, G.G.1    Palatnick, L.2    Nichol, K.A.3    Bellyou, T.4    Low, D.E.5    Hoban, D.J.6
  • 96
    • 0037764675 scopus 로고    scopus 로고
    • Antimicrobial resistance in Haemophilus influenzae and Moraxella catarrhalis respiratory tract isolates: Results of the Canadian respiratory organism susceptibility study, 1997 to 2002
    • The Cross Study Group
    • ZHANEL GG, PALATNICK L, NICHOL KA, LOW DE, THE CROSS STUDY GROUP, HOBAN DJ: Antimicrobial resistance in Haemophilus influenzae and Moraxella catarrhalis respiratory tract isolates: results of the Canadian respiratory organism susceptibility study, 1997 to 2002. Antimicrob. Agents Chemother. (2003) 47:1875-1881.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1875-1881
    • Zhanel, G.G.1    Palatnick, L.2    Nichol, K.A.3    Low, D.E.4    Hoban, D.J.5
  • 97
    • 0034989717 scopus 로고    scopus 로고
    • Susceptibility of Canadian isolates of Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae to oral antimicrobial agents
    • BLONDEAU JM, VAUGHAN D, LASKOWSKI R, BORSOS S, GROUP TCAS: Susceptibility of Canadian isolates of Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae to oral antimicrobial agents. Int. J. Antimicrob. Agents (2001) 17:457-464.
    • (2001) Int. J. Antimicrob. Agents , vol.17 , pp. 457-464
    • Blondeau, J.M.1    Vaughan, D.2    Laskowski, R.3    Borsos, S.4    Group, T.C.A.S.5
  • 98
    • 0036499123 scopus 로고    scopus 로고
    • Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in the United States: Results from the TRUST surveillance program, 1999-2000
    • THORNSBERRY C, SAHM DF, KELLY LJ et al.: Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in the United States: results from the TRUST surveillance program, 1999-2000. Clin. Infect. Dis. (2002) 34:S4-16.
    • (2002) Clin. Infect. Dis. , vol.34
    • Thornsberry, C.1    Sahm, D.F.2    Kelly, L.J.3
  • 99
    • 0030066102 scopus 로고    scopus 로고
    • In vitro and in vivo evaluations of LB20304, a new fluoronaphthyridone
    • OH J-I, PAEK K-S, AHN M-J: In vitro and in vivo evaluations of LB20304, a new fluoronaphthyridone. Antimicrob. Agents Chemother. (1996) 40:1564-1568.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 1564-1568
    • Oh, J.-I.1    Paek, K.-S.2    Ahn, M.-J.3
  • 100
    • 0033999687 scopus 로고    scopus 로고
    • Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci
    • HARDY D, AMSTERDAM D, MANDELL LA, ROTSTEIN C: Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci. Antimicrob. Agents Chemother. (2000) 44(3):802-805.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , Issue.3 , pp. 802-805
    • Hardy, D.1    Amsterdam, D.2    Mandell, L.A.3    Rotstein, C.4
  • 101
    • 0033910452 scopus 로고    scopus 로고
    • Comparative in vitro potency of gemifloxacin against European respiratory tract pathogens isolated in the Alexander Project
    • MARCHESE A, DEBBIA EA, SCHITO GC: Comparative in vitro potency of gemifloxacin against European respiratory tract pathogens isolated in the Alexander Project. J. Antimicrob. Chemother. (2000) 46(Suppl. T1):11-15.
    • (2000) J. Antimicrob. Chemother. , vol.46 , Issue.SUPPL. T1 , pp. 11-15
    • Marchese, A.1    Debbia, E.A.2    Schito, G.C.3
  • 102
    • 0034035192 scopus 로고    scopus 로고
    • Activity of gemifloxacin, a new broad-spectrum quinolone, against 200 pneumococci by four different susceptibility testing methods
    • EDNIE LM, JACOBS MR, APPELBAUM PC: Activity of gemifloxacin, a new broad-spectrum quinolone, against 200 pneumococci by four different susceptibility testing methods. J. Antimicrob. Chemother. (2000) 45(4):525-528.
    • (2000) J. Antimicrob. Chemother. , vol.45 , Issue.4 , pp. 525-528
    • Ednie, L.M.1    Jacobs, M.R.2    Appelbaum, P.C.3
  • 103
    • 0033734978 scopus 로고    scopus 로고
    • Activities of clinafloxacin, gatifloxacin, gemifloxacin and trovafloxacin against recent clinical isolates of levofloxacin-resistant Streptococcus pneumoniae
    • JORGENSEN JH, WEIGEL LM, SWENSON JM, WHITNEY CG, FERRARO MJ, TENOVER FC: Activities of clinafloxacin, gatifloxacin, gemifloxacin and trovafloxacin against recent clinical isolates of levofloxacin-resistant Streptococcus pneumoniae. Antimicrob. Agents Chemother. (2000) 44:2962-2968.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 2962-2968
    • Jorgensen, J.H.1    Weigel, L.M.2    Swenson, J.M.3    Whitney, C.G.4    Ferraro, M.J.5    Tenover, F.C.6
  • 104
    • 0033751574 scopus 로고    scopus 로고
    • A comparative in vitro surveillance study of gemifloxacin activities against 2,632 recent Streptococcus pneumoniae isolates from across Europe, North America, and South America
    • The Gemifloxacin Surveillance Study Research Group
    • HOBAN DJ, BOUCHILLON SK, KARLOWSKY JA et al.: A comparative in vitro surveillance study of gemifloxacin activities against 2,632 recent Streptococcus pneumoniae isolates from across Europe, North America, and South America. The Gemifloxacin Surveillance Study Research Group. Antimicrob. Agents Chemother. (2000) 44(11):3008-3011.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , Issue.11 , pp. 3008-3011
    • Hoban, D.J.1    Bouchillon, S.K.2    Karlowsky, J.A.3
  • 105
    • 0033846399 scopus 로고    scopus 로고
    • Evaluation of gemifloxacin (SB-265805, LB20304a): In vitro activity against over 6000 gram-positive pathogens from diverse geographic areas
    • JONES RN, PFALLER MA, ERWIN ME: Evaluation of gemifloxacin (SB-265805, LB20304a): in vitro activity against over 6000 gram-positive pathogens from diverse geographic areas. Int. J. Antimicrob. Agents Chemother. (2000) 15:227-230.
    • (2000) Int. J. Antimicrob. Agents Chemother. , vol.15 , pp. 227-230
    • Jones, R.N.1    Pfaller, M.A.2    Erwin, M.E.3
  • 106
    • 0036158946 scopus 로고    scopus 로고
    • Comparative in vitro activity of gemifloxacin to other fluoroquinolones and non-quinolone agents against Streptococcus pneumoniae, Haemophilus influenzae and Moraxrella catarrhalis in the United States in 1999-2000
    • KOETH LM, JACOBS MR, BAJAKSOUZIAN S, ZILLES A, LIN G, APPELBAUM PC: Comparative in vitro activity of gemifloxacin to other fluoroquinolones and non-quinolone agents against Streptococcus pneumoniae, Haemophilus influenzae and Moraxrella catarrhalis in the United States in 1999-2000. Int. J. Antimicrob. Agents Chemother. (2002) 19:33-37.
    • (2002) Int. J. Antimicrob. Agents Chemother. , vol.19 , pp. 33-37
    • Koeth, L.M.1    Jacobs, M.R.2    Bajaksouzian, S.3    Zilles, A.4    Lin, G.5    Appelbaum, P.C.6
  • 107
    • 0031026256 scopus 로고    scopus 로고
    • Antimicrobial activity and spectrum of LB20304, a novel fluoronaphthyridone
    • CORMICAN MG, JONES RN: Antimicrobial activity and spectrum of LB20304, a novel fluoronaphthyridone. Antimicrob. Agents Chemother. (1997) 41:204-211.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 204-211
    • Cormican, M.G.1    Jones, R.N.2
  • 108
    • 0035991984 scopus 로고    scopus 로고
    • Activities of six different quinolones against clinical respiratory isolates of Streptococcus pneumoniae with reduced susceptibility to ciprofloxacin in Spain
    • Spanish Surveillance Group for Respiratory Pathogens S:
    • PEREZ-TRALLERO E, GARCIA-REY C, MARTIN-SANCHEZ AM, AGUILAR L, GARCIA-DE-LOMAS J, RUIZ J, Spanish Surveillance Group for Respiratory Pathogens S: Activities of six different quinolones against clinical respiratory isolates of Streptococcus pneumoniae with reduced susceptibility to ciprofloxacin in Spain. Antimicrob. Agents Chemother. (2002) 46:2665-2667.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 2665-2667
    • Perez-Trallero, E.1    Garcia-Rey, C.2    Martin-Sanchez, A.M.3    Aguilar, L.4    Garcia-de-Lomas, J.5    Ruiz, J.6
  • 109
    • 0034110572 scopus 로고    scopus 로고
    • In vitro activity of gemifloxacin and other antimicrobial agents against isolates of Bordetella pertussis and Bordetella parapertussis
    • MORTENSEN JE, RODGERS GL: In vitro activity of gemifloxacin and other antimicrobial agents against isolates of Bordetella pertussis and Bordetella parapertussis. J. Antimicrob. Chemother. (2000) 45:47-49.
    • (2000) J. Antimicrob. Chemother. , vol.45 , pp. 47-49
    • Mortensen, J.E.1    Rodgers, G.L.2
  • 110
    • 0033708083 scopus 로고    scopus 로고
    • In vitro activity of gatifloxacin compared with gemifloxacin, moxifloxacin, trovafloxacin, ciprofloxacin and ofloxacin against uropathogens cultured from patients with complicated urinary tract infections
    • NABER KG, HOLLAUER K, KIRCHBAUER D, WITTE W. In vitro activity of gatifloxacin compared with gemifloxacin, moxifloxacin, trovafloxacin, ciprofloxacin and ofloxacin against uropathogens cultured from patients with complicated urinary tract infections. Int. J. Antimicrob. Agents Chemother. (2000) 16:239-243.
    • (2000) Int. J. Antimicrob. Agents Chemother. , vol.16 , pp. 239-243
    • Naber, K.G.1    Hollauer, K.2    Kirchbauer, D.3    Witte, W.4
  • 111
    • 0032735444 scopus 로고    scopus 로고
    • In vitro activities of gemifloxacin (SB 265805, LB20304) against recent clinical isolates of Chlamydia pneumoniae
    • ROBLIN PM, REZNIK T, KUTLIN A, HAMMERSCHLAG MR: In vitro activities of gemifloxacin (SB 265805, LB20304) against recent clinical isolates of Chlamydia pneumoniae. Antimicrob. Agents Chemother. (1999) 43:2806-2807.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 2806-2807
    • Roblin, P.M.1    Reznik, T.2    Kutlin, A.3    Hammerschlag, M.R.4
  • 112
    • 0034128548 scopus 로고    scopus 로고
    • In vitro activity of gemifloxacin compared with other antimicrobial agents against recent clinical isolates of streptococci
    • IEVEN M, GOOSSENS W, DE WIT S, GOOSSENS H: In vitro activity of gemifloxacin compared with other antimicrobial agents against recent clinical isolates of streptococci. J. Antimicrob. Chemother. (2000) 45(Suppl 1):51-53.
    • (2000) J. Antimicrob. Chemother. , vol.45 , Issue.SUPPL. 1 , pp. 51-53
    • Ieven, M.1    Goossens, W.2    De Wit, S.3    Goossens, H.4
  • 113
    • 0036233721 scopus 로고    scopus 로고
    • Network. TCBS: Activities of new fluoroquinolones, ketolides and other antimicrobials against blood culture isolates of viridans group streptococci from across Canada, 2000
    • GERSHON AS, DE AZAVEDO J, MCGEER A et al.: Network. TCBS: Activities of new fluoroquinolones, ketolides and other antimicrobials against blood culture isolates of viridans group streptococci from across Canada, 2000. Antimicrob. Agents Chemother. (2002) 46:1553-1556.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 1553-1556
    • Gershon, A.S.1    De Azavedo, J.2    McGeer, A.3
  • 114
    • 0033913345 scopus 로고    scopus 로고
    • Comparative activities of ciprofloxacin, clinafloxacin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin and trovafloxacin against epidemiologically defined Acinetobacter baumannii strains
    • HEINEMANN B, WISPLINGHOFF H, EDMOND MB, SEIFERT H: Comparative activities of ciprofloxacin, clinafloxacin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin and trovafloxacin against epidemiologically defined Acinetobacter baumannii strains. Antimicrob. Agents Chemother. (2000) 44:2211-2213.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 2211-2213
    • Heinemann, B.1    Wisplinghoff, H.2    Edmond, M.B.3    Seifert, H.4
  • 115
    • 0032708658 scopus 로고    scopus 로고
    • Activities of gemifloxacin (SB 265805, LB 20304) compared to those of other oral antimicrobial agents against unusual anaerobes
    • GOLDSTEIN EJ, CITRON DM, VRENI-MERRIAM C, TYRRELL K, WARREN Y: Activities of gemifloxacin (SB 265805, LB 20304) compared to those of other oral antimicrobial agents against unusual anaerobes. Antimicrob. Agents Chemother. (1999) 43:2726-2730.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 2726-2730
    • Goldstein, E.J.1    Citron, D.M.2    Vreni-Merriam, C.3    Tyrrell, K.4    Warren, Y.5
  • 116
    • 0034085333 scopus 로고    scopus 로고
    • Review of the in vitro activity of gemifloxacin against gram-positive and gram-negative anaerobic pathogens
    • GOLDSTEIN EJ: Review of the in vitro activity of gemifloxacin against gram-positive and gram-negative anaerobic pathogens. J. Antimicrob. Chemother. (2000) 45(Suppl. 1):55-65.
    • (2000) J. Antimicrob. Chemother. , vol.45 , Issue.SUPPL. 1 , pp. 55-65
    • Goldstein, E.J.1
  • 118
    • 0034923007 scopus 로고    scopus 로고
    • Activities of gemifloxacin and five other antimicrobial agents against Listeria monocytogenes and Coryneform bacteria isolated from clinical samples
    • MARTINEZ-MARTINEZ L, JOYANES P, SUAREZ AI, PEREA EJ: Activities of gemifloxacin and five other antimicrobial agents against Listeria monocytogenes and Coryneform bacteria isolated from clinical samples. Antimicrob. Agents Chemother. (2001) 45:2390-2392.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 2390-2392
    • Martinez-Martinez, L.1    Joyanes, P.2    Suarez, A.I.3    Perea, E.J.4
  • 119
    • 2542535815 scopus 로고    scopus 로고
    • Gemifloxacin once daily for 7 days compared to amoxicillin/clavulanic acid thrice daily for 10 days for the treatment of community-acquired pneumonia of suspected pneumococcal origin
    • (In Press)
    • LEOPHONTE P, FILE JR. TM, FELDMAN C: Gemifloxacin once daily for 7 days compared to amoxicillin/clavulanic acid thrice daily for 10 days for the treatment of community-acquired pneumonia of suspected pneumococcal origin. Resp. Med. (In Press).
    • Resp. Med.
    • Leophonte, P.1    File Jr., T.M.2    Feldman, C.3
  • 120
    • 2542558715 scopus 로고    scopus 로고
    • A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis
    • (In Press)
    • SETHI S, FOGARTY C, FULAMBARKER A: A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis. Resp. Med. (In Press).
    • Resp. Med.
    • Sethi, S.1    Fogarty, C.2    Fulambarker, A.3


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