Intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 11, 2000, Pages 3193-3195

  Garcia, I ^a   Pascual, A ^a   Ballesta, S ^a   Joyanes, P ^a   Perea, E J ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CIPROFLOXACIN; GEMIFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TROVAFLOXACIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; DRUG PENETRATION; DRUG UPTAKE; HUMAN; HUMAN CELL; LEUKOCYTE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ANTI-INFECTIVE AGENTS; BIOLOGICAL TRANSPORT; CELL SURVIVAL; FLUOROQUINOLONES; HUMANS; NAPHTHYRIDINES; NEUTROPHILS; STAPHYLOCOCCUS AUREUS; TEMPERATURE;

EID: 0033753211     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.11.3193-3195.2000     Document Type: Article

References (20)

1. Studies to establish quality control ranges for SB-265805 (LB20304) when using National Committee for Clinical Laboratory Standards antimicrobial susceptibility test methods
2. Uptake and intracellular activity of sparfloxacin in human polymorphonuclear leukocytes and tissue culture cells
3. Intracellular penetration and activity of BAY Y 3118 in human polymorphonuclear leukocytes
4. Contrast between phagocyte antibiotic uptake and subsequent intracellular bactericidal activity
5. Activity of gemifloxacin against penicillin- and ciprofloxacin-resistant Streptococcus pneumoniae displaying topoisomerase- and efflux-mediated resistance mechanisms
6. Clindamycin uptake by human neutrophils
7. Antimicrobial activity of LB20304, a fluoronaphthyridone, tested against anaerobic bacteria
8. Identification of distinct activation pathways of the human neutrophil NADPH-oxidase
9. Carrier-mediated system for pefloxacin uptake in human monocytes
10. In vitro and in vivo evaluations of LB20304, a new fluoronaphthyridone
11. Uptake and activity of rifapentine in human peritoneal macrophages and polymorphonuclear leukocytes
12. Fluorometric measurement of ofloxacin uptake by human polymorphonuclear leukocytes
13. Uptake and intracellular activity of an optically active ofloxacin isomer in human neutrophils and tissue culture cells
14. Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils
15. Entry of lomefloxacin and temafloxacin into human neutrophils, peritoneal macrophages, and tissue culture cells
16. Uptake and intracellular activity of antimicrobial agents in phagocytic cells
17. Uptake and intracellular activity of trovafloxacin in human phagocytes and tissue-cultured epithelial cells
18. Uptake and intracellular activity of moxifloxacin in human neutrophils and tissue-cultured epithelial cells
19. In vitro activities of gemifloxacin against recent clinical isolates of Chlamydia pneumoniae
20. Mechanisms of fluoroquinolone transport by human neutrophils