Solid phase synthesis and binding affinity of peptidyl transferase transition state mimics containing 2′-OH at P-site position A76

Nucleic Acids Research

Volumn 32, Issue 4, 2004, Pages 1502-1511

  Weinger, Joshua S ^a   Kitchen, David ^b   Scaringe, Stephen A ^b   Strobel, Scott A ^a   Muth, Gregory W ^c  

^a YALE UNIVERSITY   (United States)

^b Dharmacon Inc   (United States)

^c ST OLAF COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DERIVATIVE; ALANINE; AMINO ACID; DEOXYADENOSINE; HYDROXYL GROUP; OXYGEN; PEPTIDYLTRANSFERASE; PHENYLALANINE; PHOSPHATE; PUROMYCIN; RIBOADENOSINE; TRANSFER RNA; UNCLASSIFIED DRUG; DEOXYADENOSINE DERIVATIVE; ENZYME INHIBITOR;

3' UNTRANSLATED REGION; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SYNTHESIS; GEOMETRY; PHASE TRANSITION; PRIORITY JOURNAL; RIBOSOME; SOLID STATE; BINDING SITE; CHEMISTRY; METABOLISM; SYNTHESIS;

BINDING SITES; DEOXYADENOSINES; ENZYME INHIBITORS; PEPTIDYL TRANSFERASES; PHOSPHATES;

EID: 2542526957     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh311     Document Type: Article

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