Peptidyl transferase: Ancient and exiguous

Chemistry and Biology

Volumn 7, Issue 10, 2000, Pages

  Yarus, Michael ^a   Welch, Mark ^b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Maxygen   (United States)

Author keywords

Molecular evolution; Peptidyl transferase; Ribosome; RNA enzyme

Indexed keywords

PEPTIDYLTRANSFERASE; RIBOZYME; RNA;

BINDING SITE; CHEMISTRY; CONFORMATION; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; RIBOSOME; SHORT SURVEY;

BASE SEQUENCE; BINDING SITES; EVOLUTION, MOLECULAR; NUCLEIC ACID CONFORMATION; PEPTIDYL TRANSFERASES; RIBOSOMES; RNA; RNA, CATALYTIC;

EID: 0033781246     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(00)00027-2     Document Type: Short Survey

References (14)

1. The structural basis of ribosome activity in peptide bond synthesis
2. An inhibitor of ribosomal peptidyl transferase using transition state analogy
3. Analog approaches to the structure of the transition state in enzyme reactions
4. 23S rRNA similarity from selection for peptidyl transferase mimicry
5. Ribosome-catalyzed peptidyl transfer. Effects of cations and pH value
6. Studies on transfer ribonucleic acid-ribosome complexes. XX. Peptidyl-puromycin synthesis on mammalian polyribosomes
7. A single adenosine with a neutral pK(a) in the ribosomal transferase center
8. RNAs with dual specificity and dual RNAs with similar specificity
9. Expanding the scope of RNA catalysis
10. The modus operandi of a DNA enzyme: Enhancement of substrate basicity
11. Enrichment for RNA molecules that bind a Diels-Alder transition state analogue
12. A small catalytic RNA motif with Diels-Alderase activity