Determination of major carotenoids in human serum by liquid chromatography

Journal of Food and Drug Analysis

Volumn 12, Issue 1, 2004, Pages 79-83

  Tzeng, Min Su ^a   Yang, Feili Lo ^a   Wang Hsu, Guoo Shyng ^a   Chen, Bing Huei ^a  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Carotenoids; HPLC; Human serum

Indexed keywords

BETA CAROTENE; CAROTENOID; DICHLOROMETHANE; LYCOPENE; METHANOL; SOLVENT; XANTHOPHYLL;

ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG BLOOD LEVEL; ELDERLY CARE; FLOW RATE; FOOD COMPOSITION; FOOD INTAKE; HEALTH CENTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; SEPARATION TECHNIQUE; TOMATO;

LYCOPERSICON ESCULENTUM;

EID: 2542523717     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Helzlsouer, K. J., Comstock, G. W. and Morris, J. S. 1989. Selenium, lycopene, α-tocopherol, β-carotene, retinol and subsequent bladder cancer. Cancer Res. 49: 6144-6148.
2. Fuhrman, B., Elis, A. and Aviram, M. 1997. Hypocholesterolemic effect of lycopene and β-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. Biochem. Biophys Res. Commun. 233: 658-662.
3. Clinton, S. K. 1998. Lycopene: chemistry, biology and implications for human health and disease. Nutr. Rev. 56: 135-51.
4. Burton, G. W. and Ingold, K. U. 1984. β-carotene: an unusual type of lipid antioxidant. Science 224: 569-573.
5. Foote, C. S. and Denny, R. W. 1968. Chemistry of singlet oxygen. VII Quenching by β-carotene. J. Am. Chem. Soc. 90: 6233-6235.
6. Miller, N. J., Sampson, J., Candeias, L. P., Bramley, P. M. and Rice-Evans, C. A. 1996. Antioxidant activities of carotenes and xanthophylls. FEBS Lett. 384: 240-242.
7. Ramon, J. M., Serra, L., Cerdo, C. and Oromi, J. 1993. Dietary factors and gastric cancer risk. Cancer 71: 1731-1735.
8. Jarvinen, R., Knekt, P., Seppanen, R. and Teppo, L. 1997. Diet and breast cancer risk in a cohort of Finnish women. Cancer Lett. (Ireland) 114: 251-253.
9. Coodley, G. O., Coodley, M. K and Nelson, H. D. 1995. Micronutrients in HIV-infected women. J. Womens Health 4: 303-311.
10. Aust, O., Sies, H., Stahl, W. and Polidori, M. C. 2001. Analysis of lipophilic antioxidants in human serum and tissues: tocopherols and carotenoids. J. Chromatogr. A 936: 83-93.
11. Watzl, B., Bub, A., Brandstetter, B. R. and Rechkemmer, G. 1999. Modulation of human T-lymphocyte functions by the consumption of carotenoids-rich vegetables. Bitish J. Nutr. 82: 383-389.
12. Talwar, D., Ha, T. K., Cooney, J., Brownlee, C. and JO'Reilly, D. S. 1998. A routine method for the simultaneous measurement of retinol, α-tocopherol and five carotenoids in human plasma by reverse phase HPLC. Clinica. Chimica. Acta. 270: 85-100.
13. Chen, T. M. and Chen, B. H. 1994. Optimization of mobile phase for the HPLC of cis-trans carotene isomers. Chromatographia 39: 346-354.
14. Tai, C. Y. and Chen, B. H. 2000. Analysis and stability of carotenoids in the flowers of Daylily as affected by various treatments. J. Agric. Food Chem. 48: 5962-5968.
15. Milne, D. and Botnen, J. 1986. Retinol, α-tocopherol, lycopene, α- and β-carotene simultaneously determined in plasma by isocratic liguid chromatography. Clin. Chem. 32: 874-876.
16. Thurnham, D., Smith, E. and Flora, P. 1988. Concurrent liquid chromatographic assay of retinol, α-tocopherol, β-carotene, lycopene and β-cryptoxanthin with tocopherol acetate as internal standard. Clin. Chem. 34: 377-381.
17. Zaman, Z., Fielden, P. and Frost, P. 1993. Simultaneous determination of vitamins A and E and retinoids in plasma by reversed phase HPLC in elderly and young subjects. Chin. Chem. 39: 2229-2234.
18. Ferreira, A. L. A., Yeum, K. J., Liu, C., Smith, D., Krinsky, N. I., Wang, X. D. and Russell, R. M. 1993. Tissue distribution of lycopene in ferrets and rats after lycopene supplementation. J. Nutr. 130: 1256-1260.
19. Khachik F, Beecher G. R. and Cecil Smith, J. Jr. 1997. Identification, quantification and relative concentration of carotenoids and their metabolites in human milk and serum. Anal. Chem. 69:1873-1881.
20. Stahl, W., Schwartz, W., Sundquist, A. R. and Sies, H. 1992. Cis-trans isomers of lycopene and β-carotene in human serum and tissues. Arch. Biophy. 294: 173-177.
21. Shi, J. and Le Maguer, M. 2000. Lycopene in tomatoes: chemical and physical properties affected by food processing. Crit. Rev. Nutr. Food Sci. 40: 1-42.
22. Levy, J., Bosin, E., Feldman, B., Giat, Y, Miinster, A., Danilenko, M. and Sharoni, Y. 1995. Lycopene is a more potent inhibitor of human cancer cell proliferation than either α-carotene or β-carotene. Nutr. Cancer 24: 257-266.
23. Watzl, B., Bub, A., Blockhans, M., Herbert, B. M., Lubrmann, P. M., Neuhauser-Berthold, M. and Rechkemmer, G. 2000. Prolonged tomato juice consumption has no effect on cell-mediated immunity of well-nourished elderly men and women. J. Nutr. 130: 1719-1923.