Tyrosine phosphorylation of p62dok by p210bcr-abl inhibits RasGAP activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 5, 2000, Pages 2093-2098

  Kashige, Nobuhiro ^a,c   Carpino, Nick ^a,b,d   Kobayashi, Ryuji ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c FUKUOKA UNIVERSITY   (Japan)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Chronic myelogenous leukemia; Ras

Indexed keywords

BCR ABL PROTEIN; DNA BINDING PROTEIN; DOK1 PROTEIN, HUMAN; GAP ASSOCIATED PROTEIN P62; GAP-ASSOCIATED PROTEIN P62; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PEPTIDE; PHOSPHOPROTEIN; RNA BINDING PROTEIN; TYROSINE; CELL PROTEIN; GUANOSINE TRIPHOSPHATASE; PROTEIN DOK 1; PROTEIN TYROSINE KINASE; RAS PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING COMPETITION; CELL LINE; CELL STRAIN COS1; DRUG ANTAGONISM; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; PHOSPHORYLATION; POINT MUTATION; CHROMOSOME 22; CHROMOSOME 9; CHROMOSOME TRANSLOCATION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN CELL; IN VITRO STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CELL LINE; COS CELLS; DNA-BINDING PROTEINS; FUSION PROTEINS, BCR-ABL; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; POINT MUTATION; RAS GTPASE-ACTIVATING PROTEINS; RNA-BINDING PROTEINS; TYROSINE;

EID: 0033622043     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.040547997     Document Type: Article

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