Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates

International Journal of Antimicrobial Agents

Volumn 12, Issue 1, 1999, Pages 53-61

  Smeijsters, L J J W ^a   Franssen, F F J ^a   Naesens, L ^b   De Vries, E ^a   Holy A ^c   Balzarini, J ^b   De Clercq, E ^b   Overdulve, J P ^a  

^a Department of Infectious Diseases and Immunology   (Netherlands)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Acyclic nucleoside phosphonates; Antimalarials; DNA polymerase; Plasmodium falciparum

Indexed keywords

9 (3 HYDROXY 2 PHOSPHONOMETHOXYPROPYL)ADENINE; ACYCLIC NUCLEOSIDE; ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVE; ADEFOVIR; DNA POLYMERASE; PHOSPHONIC ACID DERIVATIVE; SR 3722; SR 3772; SR 3773; SR 3775; SR 3782; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; ERYTHROCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROBIAL GROWTH; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

ADENINE; ANIMALS; ANTIMALARIALS; CYTOSINE; DNA-DIRECTED DNA POLYMERASE; ERYTHROCYTES; GANCICLOVIR; HUMANS; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHONIC ACIDS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033043155     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(99)00003-5     Document Type: Article

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