메뉴 건너뛰기




Volumn 7, Issue 6, 2004, Pages 605-612

The prepattern transcription factor Irx2, a target of the FGF8/MAP kinase cascade, is involved in cerebellum formation

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 8; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GBX2; TRANSCRIPTION FACTOR IRX2; TRANSCRIPTION FACTOR OTX2; UNCLASSIFIED DRUG;

EID: 2542477988     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1249     Document Type: Article
Times cited : (89)

References (50)
  • 1
    • 0032739531 scopus 로고    scopus 로고
    • The role of the rhombic lip in avian cerebellum development
    • Wingate, R.J. & Hatten, M.E. The role of the rhombic lip in avian cerebellum development. Development 126, 4395-4404 (1999).
    • (1999) Development , vol.126 , pp. 4395-4404
    • Wingate, R.J.1    Hatten, M.E.2
  • 2
    • 0034919848 scopus 로고    scopus 로고
    • Inductive signal and tissue responsiveness defining the tectum and the cerebellum
    • Sato, T., Araki, I. & Nakamura, H. Inductive signal and tissue responsiveness defining the tectum and the cerebellum. Development 128, 2461-2469 (2001).
    • (2001) Development , vol.128 , pp. 2461-2469
    • Sato, T.1    Araki, I.2    Nakamura, H.3
  • 3
    • 0344588770 scopus 로고    scopus 로고
    • Identification of the vertebrate Iroquois homeobox gene family with overlapping expression during early development of the nervous system
    • Bosse, A. et al. Identification of the vertebrate Iroquois homeobox gene family with overlapping expression during early development of the nervous system. Mech. Dev. 69, 169-181 (1997).
    • (1997) Mech. Dev. , vol.69 , pp. 169-181
    • Bosse, A.1
  • 4
    • 0342393088 scopus 로고    scopus 로고
    • Expression of two novel mouse iroquois homeobox genes during neurogenesis
    • Cohen, D.R., Cheng, C.W., Cheng, S.H. & Hui, C.C. Expression of two novel mouse iroquois homeobox genes during neurogenesis. Mech. Dev. 91, 317-321 (2000).
    • (2000) Mech. Dev. , vol.91 , pp. 317-321
    • Cohen, D.R.1    Cheng, C.W.2    Cheng, S.H.3    Hui, C.C.4
  • 5
    • 0032472413 scopus 로고    scopus 로고
    • Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification
    • Bellefroid, E.J. et al. Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification. EMBO J. 17, 191-203 (1998).
    • (1998) EMBO J. , vol.17 , pp. 191-203
    • Bellefroid, E.J.1
  • 6
    • 0345267408 scopus 로고    scopus 로고
    • Xiro, a Xenopus homolog of the Drosophila Iroquois complex genes, controls development at the neural plate
    • Gómez-Skarmeta, J.L., Glavic, A., de la Calle-Mustienes, E., Modolell, J. & Mayor, R. Xiro, a Xenopus homolog of the Drosophila Iroquois complex genes, controls development at the neural plate. EMBO J. 17, 181-190 (1998).
    • (1998) EMBO J. , vol.17 , pp. 181-190
    • Gómez-Skarmeta, J.L.1    Glavic, A.2    De La Calle-Mustienes, E.3    Modolell, J.4    Mayor, R.5
  • 7
    • 0036337074 scopus 로고    scopus 로고
    • A role for iro1 and iro7 in the establishment of an anteroposterior compartment of the ectoderm adjacent to the midbrain-hindbrain boundary
    • Itoh, M., Kudoh, T., Dedekian, M., Kim, C-H. & Chitnis, A.B. A role for iro1 and iro7 in the establishment of an anteroposterior compartment of the ectoderm adjacent to the midbrain-hindbrain boundary. Development 129, 2317-2327 (2002).
    • (2002) Development , vol.129 , pp. 2317-2327
    • Itoh, M.1    Kudoh, T.2    Dedekian, M.3    Kim, C.-H.4    Chitnis, A.B.5
  • 8
    • 0034766864 scopus 로고    scopus 로고
    • Xiro-1 controls mesoderm patterning by repressing Bmp-4 expression in the Spemann organizer
    • Glavic, A., Gómez-Skarmeta, J.L. & Mayor, R. Xiro-1 controls mesoderm patterning by repressing Bmp-4 expression in the Spemann organizer. Dev. Dyn. 222, 368-376 (2001).
    • (2001) Dev. Dyn. , vol.222 , pp. 368-376
    • Glavic, A.1    Gómez-Skarmeta, J.L.2    Mayor, R.3
  • 9
    • 0035090548 scopus 로고    scopus 로고
    • The Wnt-activated Xiro-1 gene encodes a repressor that is essential for neural development and downregulates Bmp-4
    • Gómez-Skarmeta, J.L., De la Calle-Mustienes, E. & Modolell, J. The Wnt-activated Xiro-1 gene encodes a repressor that is essential for neural development and downregulates Bmp-4. Development 128, 551-560 (2001).
    • (2001) Development , vol.128 , pp. 551-560
    • Gómez-Skarmeta, J.L.1    De La Calle-Mustienes, E.2    Modolell, J.3
  • 10
    • 0034640087 scopus 로고    scopus 로고
    • A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
    • Briscoe, J., Pierani, A., Jessell, T.M. & Ericson, J. A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 101, 435-445 (2000).
    • (2000) Cell , vol.101 , pp. 435-445
    • Briscoe, J.1    Pierani, A.2    Jessell, T.M.3    Ericson, J.4
  • 11
    • 0036337489 scopus 로고    scopus 로고
    • Early subdivisions in the neural plate define distinct competence for inductive signals
    • Kobayashi, D. et al. Early subdivisions in the neural plate define distinct competence for inductive signals. Development 129, 83-93 (2002).
    • (2002) Development , vol.129 , pp. 83-93
    • Kobayashi, D.1
  • 12
    • 0030970689 scopus 로고    scopus 로고
    • Mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye
    • McNeill, H., Yang, C.H., Brodsky, M., Ungos, J. & Simon, M.A. mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye. Genes Dev. 11, 1073-1082 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 1073-1082
    • McNeill, H.1    Yang, C.H.2    Brodsky, M.3    Ungos, J.4    Simon, M.A.5
  • 13
    • 0029809523 scopus 로고    scopus 로고
    • Araucan and caupolican provide a link between compartment subdivisions and patterning of sensory organs and veins in the Drosophila wing
    • Gómez-Skarmeta, J.L. & Modolell, J. araucan and caupolican provide a link between compartment subdivisions and patterning of sensory organs and veins in the Drosophila wing. Genes Dev. 10, 2935-2946 (1996).
    • (1996) Genes Dev. , vol.10 , pp. 2935-2946
    • Gómez-Skarmeta, J.L.1    Modolell, J.2
  • 14
    • 0033452313 scopus 로고    scopus 로고
    • Compartments and organising boundaries in the Drosophila eye: The role of the homeodomain Iroquois proteins
    • Cavodeassi, F., Diez Del Corral, R., Campuzano, S. & Dominguez, M. Compartments and organising boundaries in the Drosophila eye: the role of the homeodomain Iroquois proteins. Development 126, 4933-4942 (1999).
    • (1999) Development , vol.126 , pp. 4933-4942
    • Cavodeassi, F.1    Diez Del Corral, R.2    Campuzano, S.3    Dominguez, M.4
  • 15
    • 0029919934 scopus 로고    scopus 로고
    • Araucan and caupolican, two members of the novel iroquois complex, encode homeoproteins that control proneural and vein-forming genes
    • Gómez-Skarmeta, J.L., del Corral, R.D., de la Calle-Mustienes, E. & Ferre-Marco, D.J. Araucan and caupolican, two members of the novel iroquois complex, encode homeoproteins that control proneural and vein-forming genes. Cell 85, 95-105 (1996).
    • (1996) Cell , vol.85 , pp. 95-105
    • Gómez-Skarmeta, J.L.1    Del Corral, R.D.2    De La Calle-Mustienes, E.3    Ferre-Marco, D.J.4
  • 16
    • 0033782832 scopus 로고    scopus 로고
    • Organization of mouse iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development
    • Peters, T., Dildrop, R., Ausmeier, K. & Ruther, U. Organization of mouse iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development. Genome Res. 10, 1453-1462 (2000).
    • (2000) Genome Res. , vol.10 , pp. 1453-1462
    • Peters, T.1    Dildrop, R.2    Ausmeier, K.3    Ruther, U.4
  • 17
    • 0034944731 scopus 로고    scopus 로고
    • Cloning and chromosomal mapping of human and chicken Iroquois (Irx) genes
    • Ogura, K. et al. Cloning and chromosomal mapping of human and chicken Iroquois (Irx) genes. Cytogenet. Cell. Genet. 92, 320-325 (2001).
    • (2001) Cytogenet. Cell. Genet. , vol.92 , pp. 320-325
    • Ogura, K.1
  • 18
    • 0032819495 scopus 로고    scopus 로고
    • c-Irx2 expression reveals an early subdivision of the neural plate in the chick embryo
    • Goriely, A., Diez del Corral, R. & Storey, K.G. c-Irx2 expression reveals an early subdivision of the neural plate in the chick embryo. Mech. Dev, 87, 203-206 (1999).
    • (1999) Mech. Dev. , vol.87 , pp. 203-206
    • Goriely, A.1    Diez Del Corral, R.2    Storey, K.G.3
  • 19
    • 0035114788 scopus 로고    scopus 로고
    • Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer
    • Garda, A., Echevarria, D. & Martinez, S. Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer. Mech. Dev. 101, 111-118 (2001).
    • (2001) Mech. Dev. , vol.101 , pp. 111-118
    • Garda, A.1    Echevarria, D.2    Martinez, S.3
  • 20
    • 0029960330 scopus 로고    scopus 로고
    • Midbrain development induced by FGF8 in the chick embryo
    • Crossley, P.H., Martinez, S. & Martin, G.R. Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68 (1996).
    • (1996) Nature , vol.380 , pp. 66-68
    • Crossley, P.H.1    Martinez, S.2    Martin, G.R.3
  • 21
    • 0032908043 scopus 로고    scopus 로고
    • FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression
    • Martinez, S., Crossley, P.H., Cobos, I., Rubenstein, J.L. & Martin, G.R. FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development 126, 1189-1200 (1999).
    • (1999) Development , vol.126 , pp. 1189-1200
    • Martinez, S.1    Crossley, P.H.2    Cobos, I.3    Rubenstein, J.L.4    Martin, G.R.5
  • 22
    • 0032708854 scopus 로고    scopus 로고
    • FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate
    • Liu, A., Losos, K. & Joyner, A.L. FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development 126, 4827-4838 (1999).
    • (1999) Development , vol.126 , pp. 4827-4838
    • Liu, A.1    Losos, K.2    Joyner, A.L.3
  • 23
    • 17744421146 scopus 로고    scopus 로고
    • Fgf8 and Gbx2 induction concomitant with Otx2 repression is correlated with midbrain-hindbrain fate of caudal prosencephalon
    • Hidalgo-Sanchez, M., Simeone, A. & Alvarado-Mallart, R.M. Fgf8 and Gbx2 induction concomitant with Otx2 repression is correlated with midbrain-hindbrain fate of caudal prosencephalon. Development 126, 3191-3203 (1999).
    • (1999) Development , vol.126 , pp. 3191-3203
    • Hidalgo-Sanchez, M.1    Simeone, A.2    Alvarado-Mallart, R.M.3
  • 24
    • 0032143609 scopus 로고    scopus 로고
    • Expression of Gbx-2during early development of the chick embryo
    • Shamim, H. & Mason, I. Expression of Gbx-2during early development of the chick embryo. Mech. Dev. 76, 157-159 (1998).
    • (1998) Mech. Dev. , vol.76 , pp. 157-159
    • Shamim, H.1    Mason, I.2
  • 25
    • 0033539094 scopus 로고    scopus 로고
    • The caudal limit of Otx2 expression positions the isthmic organizer
    • Broccoli, V., Boncinelli, E. & Wurst, W. The caudal limit of Otx2 expression positions the isthmic organizer. Nature 401, 164-168 (1999).
    • (1999) Nature , vol.401 , pp. 164-168
    • Broccoli, V.1    Boncinelli, E.2    Wurst, W.3
  • 26
    • 0033539146 scopus 로고    scopus 로고
    • A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer
    • Millet, S. et al. A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer. Nature 401, 161-164 (1999).
    • (1999) Nature , vol.401 , pp. 161-164
    • Millet, S.1
  • 27
    • 0036597736 scopus 로고    scopus 로고
    • In vivo electroporation: A new frontier for gene delivery and embryology
    • Ogura, T. In vivo electroporation: a new frontier for gene delivery and embryology. Differentiation 70, 163-171 (2002).
    • (2002) Differentiation , vol.70 , pp. 163-171
    • Ogura, T.1
  • 28
    • 0033042805 scopus 로고    scopus 로고
    • Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain
    • Shamim, H. et al. Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain. Development 126, 945-959 (1999).
    • (1999) Development , vol.126 , pp. 945-959
    • Shamim, H.1
  • 29
    • 0030933498 scopus 로고    scopus 로고
    • Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain
    • Lee, S.M., Danielian, P.S., Fritzsch, B. & McMahon, A.P. Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development 124, 959-969 (1997).
    • (1997) Development , vol.124 , pp. 959-969
    • Lee, S.M.1    Danielian, P.S.2    Fritzsch, B.3    McMahon, A.P.4
  • 30
    • 0030249695 scopus 로고    scopus 로고
    • Iroquois: A prepattern gene that controls the formation of bristles on the thorax of Drosophila
    • Leyns, L., Gómez-Skarmeta, J.L. & Dambly-Chaudière, C. Iroquois: a prepattern gene that controls the formation of bristles on the thorax of Drosophila. Mech. Dev. 59, 63-72 (1996).
    • (1996) Mech. Dev. , vol.59 , pp. 63-72
    • Leyns, L.1    Gómez-Skarmeta, J.L.2    Dambly-Chaudière, C.3
  • 31
    • 0033452313 scopus 로고    scopus 로고
    • Compartments and organising boundaries in the Drosophila eye: The role of the homeodomain Iroquois proteins
    • Cavodeassi, F., Diez Del Corral, R., Campuzano, S. & Dominguez, M. Compartments and organising boundaries in the Drosophila eye: the role of the homeodomain Iroquois proteins. Development 126, 4933-4942 (1999).
    • (1999) Development , vol.126 , pp. 4933-4942
    • Cavodeassi, F.1    Diez Del Corral, R.2    Campuzano, S.3    Dominguez, M.4
  • 32
    • 0032533322 scopus 로고    scopus 로고
    • Granule cell raphes and parasagittal domains of Purkinje cells: Complementary patterns in the developing chick cerebellum
    • Lin, J.C. & Cepko, C.L. Granule cell raphes and parasagittal domains of Purkinje cells: complementary patterns in the developing chick cerebellum. J. Neurosci. 18, 9342-9353 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 9342-9353
    • Lin, J.C.1    Cepko, C.L.2
  • 33
    • 0032796826 scopus 로고    scopus 로고
    • Sonic hedgehog regulates the growth and patterning of the cerebellum
    • Dahmane, N. & Ruiz-i-Altaba, A. Sonic hedgehog regulates the growth and patterning of the cerebellum. Development 126, 3089-3100 (1999).
    • (1999) Development , vol.126 , pp. 3089-3100
    • Dahmane, N.1    Ruiz-I-Altaba, A.2
  • 34
    • 0032908043 scopus 로고    scopus 로고
    • FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression
    • Martinez, S., Crossley, P.H., Cobos, I., Rubenstein, J.L. & Martin, G.R. FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development 126, 1189-1200 (1999).
    • (1999) Development , vol.126 , pp. 1189-1200
    • Martinez, S.1    Crossley, P.H.2    Cobos, I.3    Rubenstein, J.L.4    Martin, G.R.5
  • 35
    • 0035203941 scopus 로고    scopus 로고
    • Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8
    • Ye, W., Bouchard, M., Stone, D., Liu, X. & Rosenthal, A. Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8. Nat. Neurosci. 4, 1175-1181 (2001).
    • (2001) Nat. Neurosci. , vol.4 , pp. 1175-1181
    • Ye, W.1    Bouchard, M.2    Stone, D.3    Liu, X.4    Rosenthal, A.5
  • 36
    • 0031916557 scopus 로고    scopus 로고
    • An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination
    • Meyers, E.N., Lewandoski, M. & Martin, G.R. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat. Genet. 18, 136-141 (1998).
    • (1998) Nat. Genet. , vol.18 , pp. 136-141
    • Meyers, E.N.1    Lewandoski, M.2    Martin, G.R.3
  • 37
    • 0034925298 scopus 로고    scopus 로고
    • Early anterior/posterior patterning of the midbrain and cerebellum
    • Liu, A. & Joyner, A.L. Early anterior/posterior patterning of the midbrain and cerebellum. Annu. Rev. Neurosci. 24, 869-896 (2001).
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 869-896
    • Liu, A.1    Joyner, A.L.2
  • 38
    • 0037179758 scopus 로고    scopus 로고
    • Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer
    • Li, J.Y., Lao, Z. & Joyner, A.L. Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron 36, 31-43 (2002).
    • (2002) Neuron , vol.36 , pp. 31-43
    • Li, J.Y.1    Lao, Z.2    Joyner, A.L.3
  • 39
    • 0344395648 scopus 로고    scopus 로고
    • The isthmic neuroepithelium is essential for cerebellar midline fusion
    • Louvi, A., Alexandre, P., Métin, C., Wurst, W. & Wassef, M. The isthmic neuroepithelium is essential for cerebellar midline fusion. Development 130, 5319-5330 (2003).
    • (2003) Development , vol.130 , pp. 5319-5330
    • Louvi, A.1    Alexandre, P.2    Métin, C.3    Wurst, W.4    Wassef, M.5
  • 40
    • 0034880203 scopus 로고    scopus 로고
    • Tight transcriptional control of the ETS domain factors Erm and Pea3 by Fgf signaling during early zebrafish development
    • Raible, F. & Brand, M. Tight transcriptional control of the ETS domain factors Erm and Pea3 by Fgf signaling during early zebrafish development. Mech. Dev. 107, 105-117 (2001).
    • (2001) Mech. Dev. , vol.107 , pp. 105-117
    • Raible, F.1    Brand, M.2
  • 41
    • 0034931142 scopus 로고    scopus 로고
    • Sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish
    • Furthauer, M., Reifers, F., Brand, M., Thisse, B. & Thisse, C. Sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish. Development 128, 2175-2186 (2001).
    • (2001) Development , vol.128 , pp. 2175-2186
    • Furthauer, M.1    Reifers, F.2    Brand, M.3    Thisse, B.4    Thisse, C.5
  • 42
    • 0036170142 scopus 로고    scopus 로고
    • Identification of Sef, a novel modulator of FGF signalling
    • Tsang, M., Friesel, R., Kudoh, T. & Dawid, I.B. Identification of Sef, a novel modulator of FGF signalling. Nat. Cell Biol. 4, 165-169 (2002).
    • (2002) Nat. Cell Biol. , vol.4 , pp. 165-169
    • Tsang, M.1    Friesel, R.2    Kudoh, T.3    Dawid, I.B.4
  • 43
    • 0036173032 scopus 로고    scopus 로고
    • Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling
    • Furthauer, M., Lin, W., Ang, S.L., Thisse, B. & Thisse, C. Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling. Nat. Cell Biol. 4, 170-174 (2002).
    • (2002) Nat. Cell Biol. , vol.4 , pp. 170-174
    • Furthauer, M.1    Lin, W.2    Ang, S.L.3    Thisse, B.4    Thisse, C.5
  • 44
    • 0035170549 scopus 로고    scopus 로고
    • Fgf signalling through MAPK cascade is required for development of the subpallial telencephalon in zebrafish embryos
    • Shinya, M., Koshida, S., Sawada, A. & Takeda, H. Fgf signalling through MAPK cascade is required for development of the subpallial telencephalon in zebrafish embryos. Development 128, 4153-4164 (2001).
    • (2001) Development , vol.128 , pp. 4153-4164
    • Shinya, M.1    Koshida, S.2    Sawada, A.3    Takeda, H.4
  • 45
    • 0036023310 scopus 로고    scopus 로고
    • The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation
    • Glavic, A., Gómez-Skarmeta, J.L. & Mayor, R. The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation. Development 129, 1609-1621 (2002).
    • (2002) Development , vol.129 , pp. 1609-1621
    • Glavic, A.1    Gómez-Skarmeta, J.L.2    Mayor, R.3
  • 46
    • 0242412288 scopus 로고    scopus 로고
    • The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice
    • Lebel, M. et al. The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice. Mol. Cell. Biol. 23, 8216-8225 (2003).
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8216-8225
    • Lebel, M.1
  • 47
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa, H., Yamamura, K. & Miyazaki, J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108, 193-199 (1991).
    • (1991) Gene , vol.108 , pp. 193-199
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 48
    • 0028141496 scopus 로고
    • Transformation of mammalian cells by constitutively active MAP kinase kinase
    • Mansour, S.J. et al. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265, 966-970 (1994).
    • (1994) Science , vol.265 , pp. 966-970
    • Mansour, S.J.1
  • 49
    • 0011886368 scopus 로고
    • Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library
    • Pasquale, E.B. & Singer, S.J. Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library. Proc. Natl. Acad. Sci. USA 86, 5449-5453 (1989).
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5449-5453
    • Pasquale, E.B.1    Singer, S.J.2
  • 50
    • 0031882123 scopus 로고    scopus 로고
    • The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif
    • Yang, S.H., Yates, P.R., Whitmarsh, A.J., Davis, R.J. & Sharrocks, A.D. The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif. Mol. Cell. Biol. 18, 710-720 (1998).
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 710-720
    • Yang, S.H.1    Yates, P.R.2    Whitmarsh, A.J.3    Davis, R.J.4    Sharrocks, A.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.