JAB1 enhances HAND2 transcriptional activity by regulating HAND2 DNA binding

Journal of Neuroscience Research

Volumn 76, Issue 5, 2004, Pages 613-622

  Dai, Yan Shan ^a   Hao, Jianming ^a   Bonin, Christopher ^a   Morikawa, Yuka ^b   Cserjesi, Peter ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Development; HAND2; JAB1; PNS; Transcription

Indexed keywords

CELL PROTEIN; DNA; HELIX LOOP HELIX PROTEIN; JUN ACTIVATION DOMAIN BINDING PROTEIN 1; PROTEIN HAND2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADRENERGIC SYSTEM; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; EMBRYO; GENE EXPRESSION; HEART DEVELOPMENT; HUMAN; HUMAN CELL; LIMB DEVELOPMENT; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TWO HYBRID SYSTEM;

ANIMALS; AUTONOMIC NERVOUS SYSTEM; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CONSERVED SEQUENCE; DNA; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EMBRYO; ENTERIC NERVOUS SYSTEM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PRECIPITIN TESTS; PREGNANCY; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES; YEASTS; ZEBRAFISH PROTEINS;

EID: 2542456590     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20105     Document Type: Article

References (47)

1. Bae M-K, Ahn M-Y, Jeong J-W, Bae M-H, Lee YM, Bae S-K, Park J-W, Kim K-R, Kim K-W. 2001. Jab1 Interacts Directly with HIF-1alpha and Regulates Its Stability. J Biol Chem 277:9-12.
2. Bianchi E, Denti S, Granata A, Bossi G, Geginat J, Villa A, Rogge L, Pardi R. 2000. Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity. Nature 404:617-621.
3. Blaugrund E, Pham TD, Tennyson VM, Lo L, Sommer L, Anderson DJ, Gershon MD. 1996. Distinct subpopulations of enteric neuronal progenitors defined by time of development, sympathoadrenal lineage markers and Mash-1-dependence. Development 122:309-320.
4. Caballero OL, Resto V, Patturajan M, Meerzaman D, Guo MZ, Engles J, Yochem R, Ratovitski E, Sidransky D, Jen J. 2002. Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1). Oncogene 21:3003-3010.
5. Charite J, McFadden DG, Olson EN. 2000. The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development. Development 127:2461-2470.
6. Chauchereau A, Georgiakaki M, Perrin-Wolff M, Milgrom E, Loosfelt H. 2000. JAB1 interacts with both the progesterone receptor and SRC-1. J Biol Chem 275:8540-8548.
7. Claret FX, Hibi M, Dhut S, Toda T, Karin M. 1996. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature 383:453-457.
8. Cope GA, Suh GS, Aravind L, Schwarz SE, Zipursky SL, Koonin EV, Deshaies RJ. 2002. Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cull. Science 298:608-611.
9. Cserjesi P, Brown D, Lyons GE, Olson EN. 1995. Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development. Dev Biol 170:664-678.
10. Dai YS, Cserjesi P. 2002. The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer. J Biol Chem 277:12604-12612.
11. Dai YS, Cserjesi P, Markham BE, Molkentin JD. 2002. The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism. J Biol Chem 277:24390-24398.
12. Dechend R, Hirano F, Lehmann K, Heissmeyer V, Ansieau S, Wulczyn FG, Scheidereit C, Leutz A. 1999. The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators. Oncogene 18:3316-3323.
13. Deng XW, Dubiel W, Wei N, Hofmann K, Mundt K. 2000. Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development. Trends Genet 16:289.
14. Doronkin S, Djagaeva I, Beckendorf SK. 2002. CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint. Development 129:5053-5064.
15. Fernandez-Teran M, Piedra ME, Kathiriya IS, Srivastava D, Rodriguez-Rey JC, Ros MA. 2000. Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway. Development 127:2133-2142.
16. Firulli AB. 2003. A HANDful of questions: the molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors. Gene 312:27-40.
17. Firulli BA, Hadzic DB, McDaid JR, Firulli AB. 2000. The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function. J Biol Chem 275:33567-33573.
18. Firulli BA, Howard MJ, McDaid JR, McIlreavey L, Dionne KM, Centonze VE, Cserjesi P, Virshup DM, Firulli AB. 2003b. PKA, PKC and the protein phosphatase 2A Influence HAND factor function: a mechanisms for tissue specific transcriptional regulation. Mol Cell 12:1225-1237.
19. Gershon MD. 1997. Genes and lineages in the fonnation of the enteric nervous system. Curr Opin Neurobiol 7:101-109.
20. Gestblom C, Grynfeld A, Ora I, Ortoft E, Larsson C, Axelson H, Sandstedt B, Cserjesi P, Olson EN, Pahlman S. 1999. The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas. Lab Invest 79:67-79.
21. Guillemot F. 1999. Vertebrate bHLH genes and the determination of neuronal fates. Exp Cell Res 253:357-364.
22. Guillemot F, Lo LC, Johnson JE, Auerbach A, Anderson DJ, Joyner AL. 1993. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell 75:463-476.
23. Howard M, Foster DN, Cserjesi P. 1999. Expression of HAND gene products may be sufficient for the differentiation of avian neural crest-derived cells into catecholaminergic neurons in culture. Dev Biol 215:62-77.
24. Howard MJ, Stanke M, Schneider C, Wu X, Rohrer H. 2000. The transcription factor dHAND is a downstream effector of BMPs in sympathetic neuron specification. Development 127:4073-4081.
25. Kleemann R, Hausser A, Geiger G, Mischke R, Burger-Kentischer A, Flieger O, Johannes FJ, Roger T, Calandra T, Kapurniotu A, Grell M, Finkelmeier D, Brunner H, Bernhagen J. 2000. Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature 408:211-216.
26. Kwok SF, Solano R, Tsuge T, Chamovitz DA, Ecker JR, Matsui M, Deng XW. 1998. Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus mutations. Plant Cell 10:1779-1790.
27. Lee JE. 1997. Basic helix-loop-helix genes in neural development. Curr Opin Neurobiol 7:13-20.
28. Li S, Liu X, Ascoli M. 2000. p38JAB1 binds to the intracellular precursor of the lutropin/choriogonadotropin receptor and promotes its degradation. J Biol Chem 275:13386-13393.
29. Lu C, Li Y, Zhao Y, Xing G, Tang F, Wang Q, Sun Y, Wei H, Yang X, Wu C, Chen J, Guan KI K, Zhang C, Chen H, He F. 2001. Intracrine hepatopoietin potentiates AP-1 activity through JAB1 independent of MAPK pathway. FASEB J 14:14.
30. McFadden DG, McAnally J, Richardson JA, Charite J, Olson EN. 2002. Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding. Development 129:3077-3088.
31. Molkentin JD, Olson EN. 1996. Defining the regulatory networks for muscle development. Curr Opin Genet Dev 6:445-453.
32. Muller F, Rohrer H. 2002. Molecular control of ciliary neuron development: BMPs and downstream transcriptional control in the parasympathetic lineage. Development 129:5707-5717.
33. Murphy M, Bernard O, Reid K, Bartlett PF. 1991. Cell lines derived from mouse neural crest are representative of cells at various stages of differentiation. J Neurobiol 22:522-535.
34. Naumann M, Bech-Otschir D, Huang X, Ferrell K, Dubiel W. 1999. COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK. J Biol Chem 274:35297-35300.
35. O'Rourke MP, Tam PP. 2002. Twist functions in mouse development. Int J Dev Biol 46:401-413.
36. Parras CM, Schuurmans C, Scardigli R, Kim J, Anderson DJ, Guillemot F. 2002. Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity. Genes Dev 16:324-338.
37. Riddle RD, Johnson RL, Laufer E, Tabin C. 1993. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75:1401-1416.
38. Schofield JN, Day IN, Thompson RJ, Edwards YH. 1995. PGP9.5, a ubiquitin C-terminal hydrolase; pattern of mRNA and protein expression during neural development in the mouse. Brain Res Dev Brain Res 85:229-238.
39. Srivastava D, Cserjesi P, Olson EN. 1995a. A subclass of bHLH proteins required for cardiac morphogenesis. Science 270:1995-1999.
40. Srivastava D, Cserjesi P, Olson EN. 1995b. A subclass of bHLH proteins required for cardiac morphogenesis. Science 270:1995-1999.
41. Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, Olson EN. 1997. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet 16:154-160.
42. Suh GS, Poeck B, Chouard T, Oron E, Segal D, Chamovitz DA, Zipursky SL. 2002. Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells. Neuron 33:35-46.
43. Thomas T, Kurihara H, Yamagishi H, Kurihara Y, Yazaki Y, Olson EN, Srivastava D. 1998. A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme. Development 125:3005-3014.
44. Tomoda K, Kubota Y, Kato J. 1999. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 398:160-165.
45. Tomoda K, Kubota Y, Arata Y, Mori S, Maeda M, Tanaka T, Yoshida M, Yoneda-Kato N, Kato Jy J. 2001. The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. J Biol Chem 9:9.
46. Yamagishi H, Olson EN, Srivastava D. 2000. The basic helix-loop-helix transcription factor, dHAND, is required for vascular development. J Clin Invest 105:261-270.
47. Yang X, Menon S, Lykke-Andersen K, Tsuge T, Di X, Wang X, Rodriguez-Suarez RJ, Zhang H, Wei N. 2002. The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cull. Curr Biol 12:667-672.