A bovine papillomavirus-1 based vector restores the function of the low-density lipoprotein receptor in the receptor-deficient CHO-ldlA7 cell line

BMC Molecular Biology

Volumn 3, Issue , 2002, Pages

  Tammur, Jaana ^a   Sibul, Hiljar ^a,b   Ustav, Ene ^a   Ustav, Mart ^a   Metspalu, Andres ^a,b  

^a UNIVERSITY OF TARTU   (Estonia)

^b TARTU UNIVERSITY CLINICS   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA FRAGMENT; LOW DENSITY LIPOPROTEIN RECEPTOR; PLASMID VECTOR; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CELL TRANSPORT; CHO CELL; CONTROLLED STUDY; EXPRESSION VECTOR; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE; INTERNALIZATION; NONHUMAN; PAPILLOMA VIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; VIRAL GENE DELIVERY SYSTEM;

BOVINAE; BOVINE PAPILLOMAVIRUS; BOVINE PAPILLOMAVIRUS TYPE 1; BOVINE PARVOVIRUS; PAPILLOMAVIRUS;

EID: 2542450198     PISSN: 14712199     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2199-3-5     Document Type: Article

References (24)

1. Goldstein JL, Brown MS: Familial hypercholesterolemia. In: Metabolic Basis of Inherited Disease. 1989, 1215-1250
2. Bilheimer DW, Goldstein JL, Grundy SM, Starzl TE, Brown MS: Liver transplantation to provide low-density lipoprotein receptors and lower plasma cholesterol in a child with homozygous familial hypercholesterolemia. New Engl J Med 1984, 311:1658-1664
3. Zwiener RJ, Uauy R, Petruska ML, Huet BA: Low-density lipoprotein apheresis as long-term treatment for children with homozygous familial hypercholesterolemia. J Pediatr 1995, 126:728-735
4. Thompson GR, Lowenthal R, Myant NB: Plasma exchange in the management of homozygous familial hypercholesterolemia. Lancet 1975, 1:1208-1211
5. Grossman M, Raper SE, Kozarsky K, Stein EA, Engelhardt JF, Muller D, Lupien PJ, Wilson JM: Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia. Nat Genet 1994, 6(4):335-341
6. Pakkanen TM, Laitinen M, Hippelainen M, Kallionpaa H, Lehtolainen P, Leppanen P, Luoma JS, Tarvainen R, Alhava E, Yla-Herttuala S: Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of hepatocyte proliferation by combined partial liver resection and thymidine kinase-ganciclovir treatment. Gene Therapy 1999, 6:34-41
7. Castell JV, Hernandez D, Gomez-Foix AM, Guillen I, Donato T, Gomez-Lechon MJ: Adenovirus-mediated gene transfer into human hepatocytes: analysis of the biochemical functionality of transduced cells. Gene Therapy 1997, 4(5):455-464
8. Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, Herz J: Hypercholesterolemia in low-density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin Invest 1993, 92(2):83-893
9. Herz J, Gerard RD: Adenovirus-mediated transfer of low-density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc Natl Acad Sci USA 1993, 90:2812-2816
10. Xiao W, Berta SC, Lu MM, Moscioni AD, Tazelaar J, Wilson JM: Adeno-associated virus as a vector for liver-directed gene therapy. J Virol 1998, 72(12):10222-10226
11. Kalpana GV: Retroviral vectors for liver-directed gene therapy. Semin Liver Dis 1999, 19(1):27-37
12. Ilan Y, Saito H, Thummala NR, Chowdhury NR: Adenovirus-mediated gene therapy of liver diseases. Semin Liver Dis 1999, 19(1):49-59
13. Morgan RA: Genetic strategies to inhibit HIV. Mol Med Today 1999, 5(10):454-458
14. Ustav M, Stenlund A: Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. EMBO J 1991, 10(2):449-457
15. Ohe Y, Zhao D, Saijo N, Podack ER: Construction of a novel bovine papillomavirus vector without detectable transforming activity suitable for gene transfer. Hum Gene Ther 1995, 6(3):325-333
16. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual Cold Spring Harbor: Cold Spring Harbor Lab, 1989
17. Krieger M, Brown MS, Goldstein JL: Isolation of Chinese hamster cell mutants defective in the receptor-mediated endocytosis of low-density lipoprotein. Mol Biol 1981, 150(2):167-184
18. Ilves I, Kivi S, Ustav M: Long-term episomal maintenance of bovine papillomavirus type 1 plasmids is determined by attachment to host chromosomes, which is mediated by the viral E2 protein and its binding sites. J Virol 1999, 73(5):4404-4412
19. Li J, Fang B, Eisensmith RC, Li XH, Nasonkin I, Lin-Lee YC, Mims MP, Hughes A, Montgomery CD, Roberts JD, Jeremy D, Parker TS, Levine DM, Woo SLC: In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene. J Clin Invest 1995, 95(2):768-773
20. Spady DK, Cuthbert JA, Willard MN, Meidell RS: Overexpression of cholesterol 7alpha-hydroxylase (CYP7A) in mice lacking the low-density lipoprotein (LDL) receptor gene. LDL transport and plasma LDL concentrations are reduced. J Biol Chem 1998; 273(1):126-132
21. Kozarsky KF, Jooss K, Donahee M, Strauss JF 3rd, Wilson JM: Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene. Nat Genet 1996, 13(1):54-62
22. Lin YL, Borenstein LA, Selvakumar R, Ahmed R, Wettstein FO: Progression from papilloma to carcinoma is accompanied by changes in antibody response to papillomavirus proteins. J Virol 1993, 67(1):382-389
23. Wilson JM, Grossman M, Cabrera JA, Wu CH, Wu GY: A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes. J Biol Chem. 1992, 267(16):11483-9
24. Piirsoo M, Ustav E, Mandel T, Stenlund A, Ustav M: Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator. EMBO J. 1996, 15(1):1-11