-
4
-
-
0038446777
-
Sixteen novel mutations in the Cu/Zn superoxide dismutase gene in amyotrophic lateral sclerosis: a decade of discoveries, defects and disputes
-
Andersen P.M., Sims K.B., Xin W.W., Kiely R., O'Neill G., Ravits J., Pioro E., Harati Y., Brower R.D., Levine J.S., Heinicke H.U., Seltzer W., Boss M., and Brown Jr. R.H. Sixteen novel mutations in the Cu/Zn superoxide dismutase gene in amyotrophic lateral sclerosis: a decade of discoveries, defects and disputes. Amyotroph. Lateral Scler. Other Motor Neuron. Disord. 4 (2003) 62-73
-
(2003)
Amyotroph. Lateral Scler. Other Motor Neuron. Disord.
, vol.4
, pp. 62-73
-
-
Andersen, P.M.1
Sims, K.B.2
Xin, W.W.3
Kiely, R.4
O'Neill, G.5
Ravits, J.6
Pioro, E.7
Harati, Y.8
Brower, R.D.9
Levine, J.S.10
Heinicke, H.U.11
Seltzer, W.12
Boss, M.13
Brown Jr., R.H.14
-
5
-
-
0344490328
-
Therapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis
-
Angelov D.N., Waibel S., Guntinas-Lichius O., Lenzen M., Neiss W.F., Tomov T.L., Yoles E., Kipnis J., Schori H., Reuter A., Ludolph A., and Schwartz M. Therapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 100 (2003) 4790-4795
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4790-4795
-
-
Angelov, D.N.1
Waibel, S.2
Guntinas-Lichius, O.3
Lenzen, M.4
Neiss, W.F.5
Tomov, T.L.6
Yoles, E.7
Kipnis, J.8
Schori, H.9
Reuter, A.10
Ludolph, A.11
Schwartz, M.12
-
6
-
-
0038689039
-
Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration
-
Berke S.J., and Paulson H.L. Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration. Curr. Opin. Genet. Dev. 13 (2003) 253-261
-
(2003)
Curr. Opin. Genet. Dev.
, vol.13
, pp. 253-261
-
-
Berke, S.J.1
Paulson, H.L.2
-
7
-
-
0042166179
-
A new piece of the ALS puzzle
-
Cleveland J.L. A new piece of the ALS puzzle. Nat. Genet. 34 (2003) 357-358
-
(2003)
Nat. Genet.
, vol.34
, pp. 357-358
-
-
Cleveland, J.L.1
-
8
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase
-
Deng H.X., Hentati A., Tainer J.A., Iqbal Z., Cayabyab A., Hung W.Y., Getzoff E.D., Hu P., Herzfeldt B., and Roos R.P. Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 261 (1993) 1047-1051
-
(1993)
Science
, vol.261
, pp. 1047-1051
-
-
Deng, H.X.1
Hentati, A.2
Tainer, J.A.3
Iqbal, Z.4
Cayabyab, A.5
Hung, W.Y.6
Getzoff, E.D.7
Hu, P.8
Herzfeldt, B.9
Roos, R.P.10
-
9
-
-
0036895241
-
Cycloox-ygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS
-
Drachman D.B., Frank K., Dykes-Hoberg M., Teismann P., Almer G., Przedborski S., and Rothstein J.D. Cycloox-ygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS. Ann. Neurol. 52 (2002) 771-778
-
(2002)
Ann. Neurol.
, vol.52
, pp. 771-778
-
-
Drachman, D.B.1
Frank, K.2
Dykes-Hoberg, M.3
Teismann, P.4
Almer, G.5
Przedborski, S.6
Rothstein, J.D.7
-
11
-
-
0032125587
-
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
-
Hall E.D., Oostveen J.A., and Gurney M.E. Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 23 (1998) 249-256
-
(1998)
Glia
, vol.23
, pp. 249-256
-
-
Hall, E.D.1
Oostveen, J.A.2
Gurney, M.E.3
-
12
-
-
0038155130
-
Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins
-
Hyun D.H., Lee M., Halliwell B., and Jenner P. Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins. J. Neurochem. 86 (2003) 363-373
-
(2003)
J. Neurochem.
, vol.86
, pp. 363-373
-
-
Hyun, D.H.1
Lee, M.2
Halliwell, B.3
Jenner, P.4
-
13
-
-
0141816705
-
Expression and localization of cyclooxygenase-1 and -2 in human sporadic amyotrophic lateral sclerosis
-
Maihofner C., Probst-Cousin S., Bergmann M., Neuhuber W., Neundorfer B., and Heuss D. Expression and localization of cyclooxygenase-1 and -2 in human sporadic amyotrophic lateral sclerosis. Eur. J. Neurosci. 18 (2003) 1527-1534
-
(2003)
Eur. J. Neurosci.
, vol.18
, pp. 1527-1534
-
-
Maihofner, C.1
Probst-Cousin, S.2
Bergmann, M.3
Neuhuber, W.4
Neundorfer, B.5
Heuss, D.6
-
14
-
-
0036787810
-
Inflammatory processes in amyotrophic lateral sclerosis
-
McGeer P.L., and McGeer E.G. Inflammatory processes in amyotrophic lateral sclerosis. Muscle Nerve 26 (2002) 459-470
-
(2002)
Muscle Nerve
, vol.26
, pp. 459-470
-
-
McGeer, P.L.1
McGeer, E.G.2
-
15
-
-
0041664055
-
Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q
-
Ruddy D.M., Parton M.J., Al Chalabi A., Lewis C.M., Vance C., Smith B.N., Leigh P.N., Powell J.F., Siddique T., Meyjes E.P., Baas J.V.F., and De Shaw C.E. Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q. Am. J. Hum. Genet. 73 (2003) 390-396
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 390-396
-
-
Ruddy, D.M.1
Parton, M.J.2
Al Chalabi, A.3
Lewis, C.M.4
Vance, C.5
Smith, B.N.6
Leigh, P.N.7
Powell, J.F.8
Siddique, T.9
Meyjes, E.P.10
Baas, J.V.F.11
De Shaw, C.E.12
-
16
-
-
0041664059
-
Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis
-
Sapp P.C., Hosler B.A., McKenna-Yasek D., Chin W., Gann A., Genise H., Gorenstein J., Huang M., Sailer W., Scheffler M., Valesky M., Haines J.L., Pericak-Vance M., Siddique T., Horvitz H.R., and Brown Jr. R.H. Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis. Am. J. Hum. Genet. 73 (2003) 397-403
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 397-403
-
-
Sapp, P.C.1
Hosler, B.A.2
McKenna-Yasek, D.3
Chin, W.4
Gann, A.5
Genise, H.6
Gorenstein, J.7
Huang, M.8
Sailer, W.9
Scheffler, M.10
Valesky, M.11
Haines, J.L.12
Pericak-Vance, M.13
Siddique, T.14
Horvitz, H.R.15
Brown Jr., R.H.16
-
17
-
-
0036949006
-
Autoimmunity as the body's defense mechanism against the enemy within: Development of therapeutic vaccines for neurodegenerative disorders
-
Schwartz M. Autoimmunity as the body's defense mechanism against the enemy within: Development of therapeutic vaccines for neurodegenerative disorders. J. Neurovirol. 8 (2002) 480-485
-
(2002)
J. Neurovirol.
, vol.8
, pp. 480-485
-
-
Schwartz, M.1
-
18
-
-
0037871603
-
Protective autoimmunity against the enemy within: fighting glutamate toxicity
-
Schwartz M., Shaked I., Fisher J., Mizrahi T., and Schori H. Protective autoimmunity against the enemy within: fighting glutamate toxicity. Trends Neurosci. 26 (2003) 297-302
-
(2003)
Trends Neurosci.
, vol.26
, pp. 297-302
-
-
Schwartz, M.1
Shaked, I.2
Fisher, J.3
Mizrahi, T.4
Schori, H.5
-
19
-
-
0037411555
-
Neurodegenerative disorders of protein aggregation
-
Shastry B.S. Neurodegenerative disorders of protein aggregation. Neurochem. Int. 43 (2003) 1-7
-
(2003)
Neurochem. Int.
, vol.43
, pp. 1-7
-
-
Shastry, B.S.1
-
20
-
-
0742321930
-
Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis
-
Simpson E.P., Yen A.A., and Appel S.H. Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis. Curr. Opin. Rheumatol. 15 (2003) 730-736
-
(2003)
Curr. Opin. Rheumatol.
, vol.15
, pp. 730-736
-
-
Simpson, E.P.1
Yen, A.A.2
Appel, S.H.3
-
22
-
-
0037077040
-
Toxic proteins in neurodegenerative disease
-
Taylor J.P., Hardy J., and Fischbeck K.H. Toxic proteins in neurodegenerative disease. Science 296 (2002) 1991-1995
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
23
-
-
0036892683
-
Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis
-
Urushitani M., Kurisu J., Tsukita K., and Takahashi R. Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis. J. Neurochem. 83 (2002) 1030-1042
-
(2002)
J. Neurochem.
, vol.83
, pp. 1030-1042
-
-
Urushitani, M.1
Kurisu, J.2
Tsukita, K.3
Takahashi, R.4
-
24
-
-
0037388067
-
Misfolded CuZnSOD and amyotrophic lateral sclerosis
-
Valentine J.S., and Hart P.J. Misfolded CuZnSOD and amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 100 (2003) 3617-3622
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3617-3622
-
-
Valentine, J.S.1
Hart, P.J.2
|