Interleukin-6 derived from hypoxic myocytes promotes neutrophil-mediated reperfusion injury in myocardium

Journal of Thoracic and Cardiovascular Surgery

Volumn 116, Issue 3, 1998, Pages 511-517

  Sawa, Y ^a   Ichikawa, H ^a   Kagisaki, K ^a   Ohata, T ^a   Matsuda, H ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; NAFAMSTAT MESILATE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CYTOKINE RELEASE; DRUG EFFECT; DRUG MECHANISM; HEART MUSCLE REPERFUSION; HEART MUSCLE REVASCULARIZATION; HUMAN; HYPOXIA; INFLAMMATION; LEUKOCYTE ACTIVATION; PATHOGENESIS; PRIORITY JOURNAL; REPERFUSION INJURY;

EID: 0031692829     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(98)70018-2     Document Type: Article

References (19)

1. RT Engler GW Schmid-Schoenbein RS. Pavelec Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog Am J Pathol 111 1983 98 111
2. ML Entman K Youker SB Shappel C Siegel R Rothlein WJ Dreyer Neutrophil adherence to isolated adult canine myocytes: evidence for a CD18-dependent mechanism J Clin Invest 88 1991 1216 1223
3. ML Entman LH Michael RD Rossen WJ Dreyer DC Anderson AA Taylor Inflammation in the course of early myocardial ischemia FASEB J 5 1991 2529 2537
4. Y Sawa S Nakano Y Shimazaki M Nishimura T Kuratani H. Matsuda Myocardial protective effect and its mechanism of leukocyte-depleted reperfusion in neonatal rabbit hearts Ann Thorac Surg 58 1994 1386 1391
5. Y Sawa H Matsuda Y Shimazaki M Kaneko M Nishimura A Amemiya Evaluation of leukocyte-depleted terminal blood cardioplegic solution in patients undergoing elective and emergency coronary artery bypass grafting J Thorac Cardiovasc Surg 108 1994 1125 1131
6. Y Sawa K Taniguchi K Kadoba M Nishimura H Ichikawa A Amemiya Leukocyte depletion attenuates reperfusion injury in patients with left ventricular hypertrophy Circulation 93 1996 1640 1646
7. CC Chen H Matsuda Y. Sawa Effect of acyclic adenosine monophosphate phosphodiesterase inhibitor, DN-9693, on myocardial reperfusion injury Ann Thorac Surg 52 1991 495 499
8. FC Faes Y Sawa H Ichikawa Y Shimazaki T Ohashi H Fukuda Inhibition of Na/H exchanger attenuates neutrophil-mediated reperfusion injury Ann Thorac Surg 60 1995 377 381
9. Y Sawa S Bernotat-Danieloski M Stoll J. Schaper CD18-ICAM-1 dependent neutrophil-endothelial cell and neutrophil-myocyte adherence is promoted by hypoxic myocyte: evidence for hypoxic myocyte derived activating factors Circulation 84 Suppl 1991 II85
10. U Ikeda F Ohkawa Y Seino K Yamamoto Y Hidaka T Kasahara Serum interleukin-6 levels become elevated in acute myocardial infarction J Mol Cell Cardiol 24 1992 579 584
11. Y Miyao H Yasue H Ogawa I Misumi T Masuda T Sakamoto Elevated plasma interleukin-6 levels in patients with acute myocardial infarction Am Heart J 126 1993 1299 1304
12. A Herskowitz S Choi AA Ansari S. Wesseling Cytokine mRNA expression in post ischemic/reperfused myocardium Am J Pathol 146 1995 419 428
13. K Yamauchi-Takihara Y Ihara A Ogata K Yoshizaki J Azuma T. Kishimoto Hypoxic stress induces cardiac myocyte–derived interleukin-6 Circulation 91 1995 1520 1524
14. Y Sawa Y Shimazaki K Kadoba T Masai H Fukuda T Ohata Attenuation of cardiopulmonary bypass–derived inflammatory reactions reduces myocardial reperfusion injury in cardiac operations J Thorac Cardiovasc Surg 111 1996 29 35
15. HS Rugo P O'Hanley AG Bishop MK Pearce JS Abrams M Howard Local cytokine production in a murine model of Escherichia coli pyelonephritis J Clin Invest 89 1992 1032 1039
16. 1 J Immunol 142 1989 4295 4300
17. K Youker CW Smith DC Anderson D Miller LH Michael RD Rossen Neutrophil adherence to isolated adult cardiac myocytes: induction by cardiac lymph collected during ischemia and reperfusion J Clin Invest 89 1992 602 609
18. GL Kukielka CW Smith GJ LaRosa AM Manning LH Mendoza TJ Daly Interleukin-8 gene induction in the myocardium after ischemia and reperfusion in vivo J Clin Invest 95 1995 89 103
19. MS Finkel CV Oddis TD Jacob SC Watkins BG Hattler RL. Simmons Negative inotropic effects of cytokines on the heart mediated by nitric oxide Science 257 1992 387 389