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Volumn 2, Issue 1, 2005, Pages 5-9

Therapeutic HIV vaccines: An update

Author keywords

Human Immunodeficiency Virus; Human Immunodeficiency Virus Infection; Human Immunodeficiency Virus Type; Plasma Viral Load; Virologic Failure

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

EID: 25144471319     PISSN: 15483568     EISSN: 15483576     Source Type: Journal    
DOI: 10.1007/s11904-996-0002-5     Document Type: Article
Times cited : (7)

References (43)
  • 1
    • 0028041344 scopus 로고
    • Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • COI: 1:CAS:528:DyaK2cXlsFGmt7w%3D, PID: 8057491
    • Borrow P, Lewicki H, Hahn BH, et al.: Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994, 68:6103–6110.
    • (1994) J Virol , vol.68 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3
  • 2
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • COI: 1:STN:280:DyaK2c3msl2huw%3D%3D, PID: 8207839
    • Koup RA, Safrit JT, Cao Y, et al.: Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994, 68:4650–4655.
    • (1994) J Virol , vol.68 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3
  • 3
    • 0030665257 scopus 로고    scopus 로고
    • Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
    • COI: 1:CAS:528:DyaK2sXnsVGlsL0%3D, PID: 9367954
    • Rosenberg ES, Billingley JM, Caliendo AM, et al.: Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia. Science 1997, 278:1447–1450. DOI: 10.1126/science.278.5342.1447
    • (1997) Science , vol.278 , pp. 1447-1450
    • Rosenberg, E.S.1    Billingley, J.M.2    Caliendo, A.M.3
  • 4
    • 0028847578 scopus 로고
    • Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection
    • COI: 1:STN:280:DyaK2M7gslemug%3D%3D, PID: 7808485
    • Cao Y, Qin L, Zhang L, et al.: Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N Engl J Med 1995, 332:201–208. DOI: 10.1056/NEJM199501263320401
    • (1995) N Engl J Med , vol.332 , pp. 201-208
    • Cao, Y.1    Qin, L.2    Zhang, L.3
  • 5
    • 0035885920 scopus 로고    scopus 로고
    • Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection
    • COI: 1:CAS:528:DC%2BD3MXntFWgsLw%3D, PID: 11535496
    • Lieberman J, Shankar P, Manjunath N, Andersson J: Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection. Blood 2001, 98:1667–1677. DOI: 10.1182/blood.V98.6.1667
    • (2001) Blood , vol.98 , pp. 1667-1677
    • Lieberman, J.1    Shankar, P.2    Manjunath, N.3    Andersson, J.4
  • 6
    • 0034600786 scopus 로고    scopus 로고
    • HIV-specific CD8+ T cells produce antiviral cytokines but are impaired in cytolytic function
    • COI: 1:CAS:528:DC%2BD3cXkslaitLY%3D, PID: 10880527
    • Appay V, Nixon DF, Donahoe SM, et al.: HIV-specific CD8+ T cells produce antiviral cytokines but are impaired in cytolytic function. J Exp Med 2000, 192:63–75. DOI: 10.1084/jem.192.1.63
    • (2000) J Exp Med , vol.192 , pp. 63-75
    • Appay, V.1    Nixon, D.F.2    Donahoe, S.M.3
  • 7
    • 0033771293 scopus 로고    scopus 로고
    • A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon
    • COI: 1:CAS:528:DC%2BD3cXnsFOlurY%3D, PID: 11024158
    • Goepfert PA, Bansal A, Edwards BH, et al.: A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon. J Virol 2000, 74:10249–10255. DOI: 10.1128/JVI.74.21.10249-10255.2000
    • (2000) J Virol , vol.74 , pp. 10249-10255
    • Goepfert, P.A.1    Bansal, A.2    Edwards, B.H.3
  • 8
    • 0035282444 scopus 로고    scopus 로고
    • Skewed maturation of memory HIV-specific CD8 T lymphocytes
    • COI: 1:CAS:528:DC%2BD3MXhvVSlsLs%3D, PID: 11242051
    • Champagne P, Ogg GS, King AS, et al.: Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 2001, 410:106–111. DOI: 10.1038/35065118
    • (2001) Nature , vol.410 , pp. 106-111
    • Champagne, P.1    Ogg, G.S.2    King, A.S.3
  • 9
    • 0034749278 scopus 로고    scopus 로고
    • Transient mobilization of human immunodeficiency virus (HIV)-specific CD4 T helper cells fails to control virus rebounds during intermittent antiretroviral therapy in chronic HIV type 1 infection
    • COI: 1:CAS:528:DC%2BD3cXovV2jtLo%3D, PID: 11119593
    • Carcelain G, Tubiana R, Samri A, et al.: Transient mobilization of human immunodeficiency virus (HIV)-specific CD4 T helper cells fails to control virus rebounds during intermittent antiretroviral therapy in chronic HIV type 1 infection. J Virol 2001, 75:234–241. DOI: 10.1128/JVI.75.1.234-241.2001
    • (2001) J Virol , vol.75 , pp. 234-241
    • Carcelain, G.1    Tubiana, R.2    Samri, A.3
  • 10
    • 3042807072 scopus 로고    scopus 로고
    • Therapeutic vaccines for chronic infections
    • COI: 1:CAS:528:DC%2BD2cXlsV2gtr0%3D, PID: 15247470
    • Autran B, Carcelain G, Combadiere B, Debre P: Therapeutic vaccines for chronic infections. Science 2004, 305:205–208. DOI: 10.1126/science.1100600
    • (2004) Science , vol.305 , pp. 205-208
    • Autran, B.1    Carcelain, G.2    Combadiere, B.3    Debre, P.4
  • 11
    • 0030896310 scopus 로고    scopus 로고
    • Vaccine therapy in early HIV-1 infection using a recombinant canarypox virus expressing gp160MN (ALVAC-HIV): a double-blind controlled randomized study of safety and immunogenicity
    • COI: 1:STN:280:DyaK2s3ovVKltw%3D%3D, PID: 9143616
    • Tubiana R, Gomard E, Fleury H, et al.: Vaccine therapy in early HIV-1 infection using a recombinant canarypox virus expressing gp160MN (ALVAC-HIV): a double-blind controlled randomized study of safety and immunogenicity. AIDS 1997, 11:819–820.
    • (1997) AIDS , vol.11 , pp. 819-820
    • Tubiana, R.1    Gomard, E.2    Fleury, H.3
  • 12
    • 0033594730 scopus 로고    scopus 로고
    • Therapeutic immunisation with recombinant gp160 in HIV-1 infection: a randomized double-blind placebo-controlled trial. Nordic VAC-04 study group
    • Sandrom E, Wahren B: Therapeutic immunisation with recombinant gp160 in HIV-1 infection: a randomized double-blind placebo-controlled trial. Nordic VAC-04 study group. Lancet 1999, 353:1735–1742. DOI: 10.1016/S0140-6736(98)06493-9
    • (1999) Lancet , vol.353 , pp. 1735-1742
    • Sandrom, E.1    Wahren, B.2
  • 13
    • 0033790862 scopus 로고    scopus 로고
    • Two double-blinded, randomized, comparative trial of four human immunodeficiency virus type 1 (HIV-1) envelope vaccines in HIV-1-infected individuals across a spectrum of disease severity: AIDS clinical trials groups 209 and 214
    • COI: 1:CAS:528:DC%2BD3cXotVOmsr8%3D, PID: 11023459
    • Schooley RT, Spino C, Kuritzkes D, et al.: Two double-blinded, randomized, comparative trial of four human immunodeficiency virus type 1 (HIV-1) envelope vaccines in HIV-1-infected individuals across a spectrum of disease severity: AIDS clinical trials groups 209 and 214. J Infect Dis 2000, 182:1357–1364. DOI: 10.1086/315860
    • (2000) J Infect Dis , vol.182 , pp. 1357-1364
    • Schooley, R.T.1    Spino, C.2    Kuritzkes, D.3
  • 14
    • 0034330601 scopus 로고    scopus 로고
    • Evaluation of HIV-1 immunogen, an immunologic modifier, administered to patients infected with HIV having 300 to 549 x 106/L CD4 cell counts: a randomized controlled trial
    • COI: 1:CAS:528:DC%2BD3cXot1Wru7w%3D, PID: 11056590
    • Kahn JO, Cherng DW, Mayer K, et al.: Evaluation of HIV-1 immunogen, an immunologic modifier, administered to patients infected with HIV having 300 to 549 x 106/L CD4 cell counts: a randomized controlled trial. JAMA 2000, 284:2193–2202. DOI: 10.1001/jama.284.17.2193
    • (2000) JAMA , vol.284 , pp. 2193-2202
    • Kahn, J.O.1    Cherng, D.W.2    Mayer, K.3
  • 15
    • 0036168676 scopus 로고    scopus 로고
    • Safety and immunogenicity of ALVAC vCP1452 and recombinant gp160 in newly human immunodeficiency virus type 1-infected patients treated with prolonged highly active antiretroviral therapy
    • COI: 1:CAS:528:DC%2BD38Xht1Kqtbo%3D, PID: 11836398
    • Jin X, Gao X, Ramanathan Jr M, et al.: Safety and immunogenicity of ALVAC vCP1452 and recombinant gp160 in newly human immunodeficiency virus type 1-infected patients treated with prolonged highly active antiretroviral therapy. J Virol 2002, 76:2206–2216. DOI: 10.1128/jvi.76.5.2206-2216.2002
    • (2002) J Virol , vol.76 , pp. 2206-2216
    • Jin, X.1    Gao, X.2    Ramanathan, M.3
  • 16
    • 0036720475 scopus 로고    scopus 로고
    • Discontinuation of antiretroviral therapy commenced early during the course of human immunodeficiency virus type 1 infection, with or without adjunctive vaccination
    • COI: 1:CAS:528:DC%2BD38XnsVSltbk%3D, PID: 12195350
    • Markowitz M, Jin X, Hurley A, et al.: Discontinuation of antiretroviral therapy commenced early during the course of human immunodeficiency virus type 1 infection, with or without adjunctive vaccination. J Infect Dis 2002, 186:634–643. DOI: 10.1086/342559
    • (2002) J Infect Dis , vol.186 , pp. 634-643
    • Markowitz, M.1    Jin, X.2    Hurley, A.3
  • 17
    • 0034727073 scopus 로고    scopus 로고
    • Immune control of HIV-1 after early treatment of acute infection
    • COI: 1:CAS:528:DC%2BD3cXntlSrsrk%3D, PID: 11029005
    • Rosenberg ES, Altfeld M, Poon SH, et al.: Immune control of HIV-1 after early treatment of acute infection. Nature 2000, 407:523–526. DOI: 10.1038/35035103
    • (2000) Nature , vol.407 , pp. 523-526
    • Rosenberg, E.S.1    Altfeld, M.2    Poon, S.H.3
  • 18
    • 0037183954 scopus 로고    scopus 로고
    • Limited immune restoration after 3 years’ suppression of HIV-1 replication in patients with moderately advanced disease
    • COI: 1:CAS:528:DC%2BD38XnsVWmt7o%3D, PID: 12351945
    • Valdez H, Connick E, Smith KY, et al.: Limited immune restoration after 3 years’ suppression of HIV-1 replication in patients with moderately advanced disease. AIDS 2002, 16:1859–1866. DOI: 10.1097/00002030-200209270-00002
    • (2002) AIDS , vol.16 , pp. 1859-1866
    • Valdez, H.1    Connick, E.2    Smith, K.Y.3
  • 19
    • 0037108925 scopus 로고    scopus 로고
    • Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection
    • COI: 1:CAS:528:DC%2BD38XotVKmt7c%3D, PID: 12370434
    • Oxenius A, Price DA, Gunthard HF, et al.: Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection. Proc Natl Acad Sci USA 2002, 99:13747–13752. DOI: 10.1073/pnas.202372199
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13747-13752
    • Oxenius, A.1    Price, D.A.2    Gunthard, H.F.3
  • 20
    • 0032719664 scopus 로고    scopus 로고
    • HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy
    • Ortiz GM, Nixon DF, Trkola A, et al.: HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy. J Clin Invest 1999, 104:13–18. DOI: 10.1172/JCI7371
    • (1999) J Clin Invest , vol.104 , pp. 13-18
    • Ortiz, G.M.1    Nixon, D.F.2    Trkola, A.3
  • 21
    • 85135183409 scopus 로고    scopus 로고
    • Analysis of Nef-specific T-cells, viral rebound and autologous viral sequences during structured treatment interruption after therapeutic vaccination with a MVABN-Nef vaccine in HIV-1-infected patients on HAART [abstract]
    • . Boston, MA, February 10–14, 2003
    • Harrer E, Bauerle M, Ferstl B, et al.: Analysis of Nef-specific T-cells, viral rebound and autologous viral sequences during structured treatment interruption after therapeutic vaccination with a MVABN-Nef vaccine in HIV-1-infected patients on HAART [abstract]. Paper presented at the 10th Conference on Retrovirus and Opportunistic Infections. Boston, MA, February 10–14, 2003.
    • Paper Presented at the 10Th Conference on Retrovirus and Opportunistic Infections
    • Harrer, E.1    Bauerle, M.2    Ferstl, B.3
  • 22
    • 0038205366 scopus 로고    scopus 로고
    • Augmentation of HIV-1-specific T helper cell responses in chronic HIV-1 infection by therapeutic immunization
    • COI: 1:CAS:528:DC%2BD3sXksVOmtr4%3D, PID: 12819512
    • Robbins GK, Addo MM, Troung H, et al.: Augmentation of HIV-1-specific T helper cell responses in chronic HIV-1 infection by therapeutic immunization. AIDS 2003, 17:1121–1126. DOI: 10.1097/00002030-200305230-00002
    • (2003) AIDS , vol.17 , pp. 1121-1126
    • Robbins, G.K.1    Addo, M.M.2    Troung, H.3
  • 23
    • 4744347790 scopus 로고    scopus 로고
    • HLA-and dose-dependent immunogenicity of a peptide-based HIV-1 immunotherapy candidate (Vacc-4x)
    • COI: 1:CAS:528:DC%2BD2cXnt12itro%3D, PID: 15353973
    • Kran AM, Sorensen B, Nyhus J, et al.: HLA-and dose-dependent immunogenicity of a peptide-based HIV-1 immunotherapy candidate (Vacc-4x). AIDS 2004, 18:1875–1883. DOI: 10.1097/00002030-200409240-00003
    • (2004) AIDS , vol.18 , pp. 1875-1883
    • Kran, A.M.1    Sorensen, B.2    Nyhus, J.3
  • 24
    • 2942627435 scopus 로고    scopus 로고
    • Safety and immunogenicity of a polyvalent peptide CA-V3 HIV vaccine in conjunction with IL-12
    • PID: 15166537
    • Sha BE, Onorato M, Bartlett JA, et al.: Safety and immunogenicity of a polyvalent peptide CA-V3 HIV vaccine in conjunction with IL-12. AIDS 2004, 18:1203–1216. DOI: 10.1097/00002030-200405210-00015
    • (2004) AIDS , vol.18 , pp. 1203-1216
    • Sha, B.E.1    Onorato, M.2    Bartlett, J.A.3
  • 25
    • 1842531844 scopus 로고    scopus 로고
    • Long-term persistence of vaccination and HAART to human immunodeficiency virus (HIV)
    • PID: 15068851
    • Boström AC, Hejdeman B, Matsuda R, et al.: Long-term persistence of vaccination and HAART to human immunodeficiency virus (HIV). Vaccine 2004, 22:1683–1691. DOI: 10.1016/j.vaccine.2003.09.049
    • (2004) Vaccine , vol.22 , pp. 1683-1691
    • Boström, A.C.1    Hejdeman, B.2    Matsuda, R.3
  • 26
    • 4344652155 scopus 로고    scopus 로고
    • DNA immunization with HIV early genes in HIV type 1-infected patients on highly active antiretroviral therapy
    • COI: 1:CAS:528:DC%2BD2cXmvVart7c%3D
    • Hejdeman B, Bostrom AC, Matsuda R, et al.: DNA immunization with HIV early genes in HIV type 1-infected patients on highly active antiretroviral therapy. AIDS Res Hum Retrovirus 2004, 20:860–870. DOI: 10.1089/0889222041725190
    • (2004) AIDS Res Hum Retrovirus , vol.20 , pp. 860-870
    • Hejdeman, B.1    Bostrom, A.C.2    Matsuda, R.3
  • 27
    • 85135177956 scopus 로고    scopus 로고
    • Therapeutic Vaccination with ALVAC-HIV vCP1433: A Recombinant Canarypox Vaccine in Chronically HIV-1 Infected Patients Treated with HAART: VACCITER (ANRS 094) [abstract]
    • Boston, MA, February 10–14, 2003
    • Tubiana R: Therapeutic Vaccination with ALVAC-HIV vCP1433: A Recombinant Canarypox Vaccine in Chronically HIV-1 Infected Patients Treated with HAART: VACCITER (ANRS 094) [abstract]. Paper presented at the 10th Conference on Retrovirus and Opportunistic Infections. Boston, MA, February 10–14, 2003.
    • Paper Presented at the 10Th Conference on Retrovirus and Opportunistic Infections.
    • Tubiana, R.1
  • 28
    • 85135159946 scopus 로고    scopus 로고
    • Evaluation of two therapeutic HIV vaccination regimens in HAART-treated primary HIV infection subjects following analytical treatment interruption: QUEST PROB3005, a randomized, placebo-controlled study [abstract]
    • San Francisco, CA, February 8–11, 2004
    • Kinloch S, Perrin L, Hoen B, et al.: Evaluation of two therapeutic HIV vaccination regimens in HAART-treated primary HIV infection subjects following analytical treatment interruption: QUEST PROB3005, a randomized, placebo-controlled study [abstract]. Paper presented at the 11th Conference on Retrovirus and Opportunistic Infections. San Francisco, CA, February 8–11, 2004.
    • Paper Presented at the 11Th Conference on Retrovirus and Opportunistic Infections.
    • Kinloch, S.1    Perrin, L.2    Hoen, B.3
  • 29
    • 11244352217 scopus 로고    scopus 로고
    • Randomized, placebocontrolled, phase 1/2a evaluation of the safety, biological activity and antiretroviral properties of an avipox virus vaccine expressing HIV gag-pol and interferon-g in HIV-1 infected subjects [abstract]
    • San Francisco, CA, February 8–11
    • Cooper D, Workman C, Puls R, et al.: Randomized, placebocontrolled, phase 1/2a evaluation of the safety, biological activity and antiretroviral properties of an avipox virus vaccine expressing HIV gag-pol and interferon-g in HIV-1 infected subjects [abstract]. Paper presented at the 11th Conference on Retrovirus and Opportunistic Infections. San Francisco, CA, February 8–11, 2004.
    • (2004) Paper Presented at the 11Th Conference on Retrovirus and Opportunistic Infections
    • Cooper, D.1    Workman, C.2    Puls, R.3
  • 30
    • 2642567900 scopus 로고    scopus 로고
    • HIV immune and virological responses following the administration of IL-2 either alone or combined to ALVAC-HIV 1433 and HIV lipopeptides in patients treated early with HAART during primary infection: The ANRS 095 randomized study [abstract]
    • Goujard C, Marcellin F, Chavez H, et al.: HIV immune and virological responses following the administration of IL-2 either alone or combined to ALVAC-HIV 1433 and HIV lipopeptides in patients treated early with HAART during primary infection: the ANRS 095 randomized study [abstract]. Paper presented at the 11th Conference on Retrovirus and Opportunistic Infections. San Francisco, CA, February 8–11, 2004.
    • (2004) Paper Presented at the 11Th Conference on Retrovirus and Opportunistic Infections. San Francisco, CA, February 8–11
    • Goujard, C.1    Marcellin, F.2    Chavez, H.3
  • 32
    • 3843119977 scopus 로고    scopus 로고
    • Therapeutic immunization with an inactivated HIV-1 immunogen plus antiretrovirals versus therapy alone in asymptomatic HIV-infected subjects
    • COI: 1:CAS:528:DC%2BD2cXmsVCqsbk%3D, PID: 15297045
    • Fernandez-Cruz E, Moreno S, Navarro J, et al.: Therapeutic immunization with an inactivated HIV-1 immunogen plus antiretrovirals versus therapy alone in asymptomatic HIV-infected subjects. Vaccine 2004, 22:2966–2973. DOI: 10.1016/j.vaccine.2004.03.040
    • (2004) Vaccine , vol.22 , pp. 2966-2973
    • Fernandez-Cruz, E.1    Moreno, S.2    Navarro, J.3
  • 33
    • 4644372686 scopus 로고    scopus 로고
    • Delayed progression to AIDS in volunteers treated with long-term HIV-1 Immunogen (REMUNE) therapy in Thailand
    • COI: 1:CAS:528:DC%2BD2cXpslCrtb8%3D, PID: 15369506
    • Chantratita W, Sukeepaisarncharoen W, Chandeying V, et al.: Delayed progression to AIDS in volunteers treated with long-term HIV-1 Immunogen (REMUNE) therapy in Thailand. HIV Med 2004, 5:317–325. DOI: 10.1111/j.1468-1293.2004.00230.x
    • (2004) HIV Med , vol.5 , pp. 317-325
    • Chantratita, W.1    Sukeepaisarncharoen, W.2    Chandeying, V.3
  • 34
    • 11144283687 scopus 로고    scopus 로고
    • Therapeutic dendritic-cell vaccine for chronic HIV-1 infection
    • Epub ahead of print
    • Lu W, Arraes LC, Ferreira WT, Andrieu JM: Therapeutic dendritic-cell vaccine for chronic HIV-1 infection. Nat Med 2004. Epub ahead of print.
    • (2004) Nat Med
    • Lu, W.1    Arraes, L.C.2    Ferreira, W.T.3    Andrieu, J.M.4
  • 35
    • 0032862292 scopus 로고    scopus 로고
    • Characterization of a multilipopeptides mixture used as an HIV-1 vaccine candidate
    • COI: 1:CAS:528:DyaK1MXnsVegtbs%3D, PID: 10506650
    • Klinguer C, David D, Kouach M, et al.: Characterization of a multilipopeptides mixture used as an HIV-1 vaccine candidate. Vaccine 1999, 18:259–267. DOI: 10.1016/S0264-410X(99)00196-6
    • (1999) Vaccine , vol.18 , pp. 259-267
    • Klinguer, C.1    David, D.2    Kouach, M.3
  • 36
  • 37
    • 0035199494 scopus 로고    scopus 로고
    • The effects of an HIV-1 immunogen (Remune) on viral load, CD4 cells counts and HIV-specific immunity in a double-blind, randomized, adjuvant-controlled subset study in HIV infected subjects regardless of concomitant antiviral drugs
    • Turner JL, Kostman JR, Aquino A, et al.: The effects of an HIV-1 immunogen (Remune) on viral load, CD4 cells counts and HIV-specific immunity in a double-blind, randomized, adjuvant-controlled subset study in HIV infected subjects regardless of concomitant antiviral drugs. HIV Med 2001, 2:65–67. DOI: 10.1046/j.1468-1293.2001.00051.x
    • (2001) HIV Med , vol.2 , pp. 65-67
    • Turner, J.L.1    Kostman, J.R.2    Aquino, A.3
  • 38
    • 0028358922 scopus 로고
    • Effect of immunization with inactivated gp120-depleted human immunodeficiency virus type 1 (HIV-1) immunogen on HIV-1 immunity, viral DNA, and percentage of CD4 cells
    • COI: 1:STN:280:DyaK2c3ltlGrsQ%3D%3D, PID: 7910836
    • Trauger RJ, Ferre F, Daigle AE, et al.: Effect of immunization with inactivated gp120-depleted human immunodeficiency virus type 1 (HIV-1) immunogen on HIV-1 immunity, viral DNA, and percentage of CD4 cells. J Infect Dis 1994, 169:1256–1264.
    • (1994) J Infect Dis , vol.169 , pp. 1256-1264
    • Trauger, R.J.1    Ferre, F.2    Daigle, A.E.3
  • 39
    • 0031986269 scopus 로고    scopus 로고
    • Safety and immunogenicity of REMUNE in HIV-infected Thai subjects
    • COI: 1:CAS:528:DyaK1cXltVCjsg%3D%3D, PID: 9607022
    • Limsuwan A, Churdboonchart V, Moss RB, et al.: Safety and immunogenicity of REMUNE in HIV-infected Thai subjects. Vaccine 1998, 16:142–149. DOI: 10.1016/S0264-410X(97)88327-2
    • (1998) Vaccine , vol.16 , pp. 142-149
    • Limsuwan, A.1    Churdboonchart, V.2    Moss, R.B.3
  • 40
    • 0037529289 scopus 로고    scopus 로고
    • Sometimes help may not be enough
    • PID: 12819528
    • Lederman MM, Douek DC: Sometimes help may not be enough. AIDS 2003, 17:1249–1251. DOI: 10.1097/00002030-200305230-00018
    • (2003) AIDS , vol.17 , pp. 1249-1251
    • Lederman, M.M.1    Douek, D.C.2
  • 41
    • 4644249757 scopus 로고    scopus 로고
    • Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells
    • COI: 1:CAS:528:DC%2BD2cXnvFeisro%3D, PID: 15381726, This study shows that HIV-specific IL-2 secreting CD4 T cells elicited by therapeutic immunization may correct vitro the functional defect of cytotoxic T lymphocytes from chronically HIV infected patients
    • Lichterfeld M, Kaufmann DE, Yu XG, et al.: Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells. J Exp Med 2004, 200:701–712. This study shows that HIV-specific IL-2 secreting CD4 T cells elicited by therapeutic immunization may correct in vitro the functional defect of cytotoxic T lymphocytes from chronically HIV infected patients. DOI: 10.1084/jem.20041270
    • (2004) J Exp Med , vol.200 , pp. 701-712
    • Lichterfeld, M.1    Kaufmann, D.E.2    Yu, X.G.3
  • 42
    • 0034794620 scopus 로고    scopus 로고
    • Study protocol for the evaluation of the potential for durable viral suppression after quadruple HAART with or without HIV vaccination: The QUEST study
    • COI: 1:STN:280:DC%2BD3MrmslWquw%3D%3D, PID: 11673819
    • Goh LE, Perrin L, Hoen B, et al.: Study protocol for the evaluation of the potential for durable viral suppression after quadruple HAART with or without HIV vaccination: The QUEST study. HIV Clin Trials 2001, 2:438–444. DOI: 10.1310/7V45-PHYR-8BU6-DLUN
    • (2001) HIV Clin Trials , vol.2 , pp. 438-444
    • Goh, L.E.1    Perrin, L.2    Hoen, B.3
  • 43
    • 85135177841 scopus 로고    scopus 로고
    • Extended follow-up of the ANRS 093 randomized study: Evaluation of of ALVAC-VIH 1433 and HIV lipopeptides (Lipo-6T) combined with SC IL-2 in chronically HIV-infected patients [abstract]
    • Paris, France, July 13–17, 2003
    • Levy Y, Durier C, Lascaux AS, et al.: Extended follow-up of the ANRS 093 randomized study: evaluation of of ALVAC-VIH 1433 and HIV lipopeptides (Lipo-6T) combined with SC IL-2 in chronically HIV-infected patients [abstract]. Paper presented at the 2nd IAS Conference on HIV pathogenesis and treatment. Paris, France, July 13–17, 2003.
    • Paper Presented at the 2Nd IAS Conference on HIV Pathogenesis and Treatment.
    • Levy, Y.1    Durier, C.2    Lascaux, A.S.3


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