-
1
-
-
0032962975
-
Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer
-
Lechardeur, D. et al.: Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer. Gene Ther., 6: 482-497 (1999).
-
(1999)
Gene Ther.
, vol.6
, pp. 482-497
-
-
Lechardeur, D.1
-
2
-
-
0027181381
-
Intracellular disposition and metabolism of fluorescen-tly-labeled unmodified and modified oligonucleotides microinjected into mammalian cells
-
Fisher, T. L., Terhorst, T., Cao, X. and Wagner, R. W.: Intracellular disposition and metabolism of fluorescen-tly-labeled unmodified and modified oligonucleotides microinjected into mammalian cells. Nucleic Acids Res., 21: 3857-3865 (1993).
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3857-3865
-
-
Fisher, T.L.1
Terhorst, T.2
Cao, X.3
Wagner, R.W.4
-
3
-
-
0033981544
-
Metabolism of antisense oligonucleotides in rat liver homogenates
-
Crooke, R. M. et al.: Metabolism of antisense oligonucleotides in rat liver homogenates. J. Pharmacol. Exp. Ther., 292: 140-149 (2000).
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 140-149
-
-
Crooke, R.M.1
-
4
-
-
0029859405
-
Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma
-
Caruso, M., Pham Nguyen K., Kwong, Y. L., Xu, B., Kosai, K. I., Finegold, M., Woo, S. L. and Chen, S. H.,: Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma. Proc. Natl. Acad. Sci. USA, 93: 11302-11306 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11302-11306
-
-
Caruso, M.1
Pham Nguyen, K.2
Kwong, Y.L.3
Xu, B.4
Kosai, K.I.5
Finegold, M.6
Woo, S.L.7
Chen, S.H.8
-
5
-
-
0029848051
-
Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12
-
Bramson, J. L., Hitt, M., Addison, C. L., Muller, W. J., Gauldie, J. and Graham, F. L.: Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12. Hum. Gene Ther., 7: 1995-2002 (1996).
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1995-2002
-
-
Bramson, J.L.1
Hitt, M.2
Addison, C.L.3
Muller, W.J.4
Gauldie, J.5
Graham, F.L.6
-
6
-
-
0031564326
-
In vivo therapy of hepatocellular carcinoma with a tumor-specific adenoviral vector expressing interleukin-2
-
Bui, L. A., Butterfield, L. H., Kim, J. Y., Ribas, A., Seu, P., Lau, R., Glaspy, J. A., McBride, W. H. and Economou, J. S.: In vivo therapy of hepatocellular carcinoma with a tumor-specific adenoviral vector expressing interleukin-2. Hum. Gene Ther., 8: 2173-2182 (1997).
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 2173-2182
-
-
Bui, L.A.1
Butterfield, L.H.2
Kim, J.Y.3
Ribas, A.4
Seu, P.5
Lau, R.6
Glaspy, J.A.7
McBride, W.H.8
Economou, J.S.9
-
7
-
-
0032549487
-
Combination therapy with interleukin-2 and wild-type p53 expressed by adenoviral vectors potentiates tumor regression in a murine model of breast cancer
-
Putzer, B. M., Bramson, J. L., Addison, C. L., Hitt, M., Siegel, P. M., Muller, W. J. and Graham, F. L.: Combination therapy with interleukin-2 and wild-type p53 expressed by adenoviral vectors potentiates tumor regression in a murine model of breast cancer. Hum. Gene Ther., 9: 707-718 (1998).
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 707-718
-
-
Putzer, B.M.1
Bramson, J.L.2
Addison, C.L.3
Hitt, M.4
Siegel, P.M.5
Muller, W.J.6
Graham, F.L.7
-
8
-
-
0028907313
-
RG-2 glioma growth attenuation and severe brain edema caused by local production of interleukin-2 and interferon-gamma
-
Tjuvajev, J., Gansbacher, B., Desai, R., Beattie, B., Kaplitt, M., Matei, C., Koutcher, J., Gilboa, E. and Blasberg, R.: RG-2 glioma growth attenuation and severe brain edema caused by local production of interleukin-2 and interferon-gamma. Cancer Res., 55: 1902-1910 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 1902-1910
-
-
Tjuvajev, J.1
Gansbacher, B.2
Desai, R.3
Beattie, B.4
Kaplitt, M.5
Matei, C.6
Koutcher, J.7
Gilboa, E.8
Blasberg, R.9
-
9
-
-
0030931602
-
Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression
-
Putzer, B. M., Hitt, M., Muller, W. J., Emtage, P., Gauldie, J. and Graham, F. L.: Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. Proc. Natl. Acad. Sci. USA, 94: 10889-10994 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10889-10994
-
-
Putzer, B.M.1
Hitt, M.2
Muller, W.J.3
Emtage, P.4
Gauldie, J.5
Graham, F.L.6
-
10
-
-
0030026213
-
Efficient gene transfer into mammalian cells using fusogenic liposome
-
Mizuguchi, H., et al.: Efficient gene transfer into mammalian cells using fusogenic liposome. Biochem. Biophs. Res. Commun., 218: 402-407 (1996).
-
(1996)
Biochem. Biophs. Res. Commun.
, vol.218
, pp. 402-407
-
-
Mizuguchi, H.1
-
11
-
-
85009562278
-
A novel gene transfer system using fusogenic liposomes
-
Mizuguchi, H., et al.: A novel gene transfer system using fusogenic liposomes. Progress in Drug Delivery System, V: 149-152 (1996).
-
(1996)
Progress in Drug Delivery System
, pp. 149-152
-
-
Mizuguchi, H.1
-
12
-
-
85024467306
-
Development of fusogenic liposomes and its application to gene therapy
-
(MRS-J)
-
Mizuguchi, H., et al.: Development of fusogenic liposomes and its application to gene therapy. Transaction of the Materials Research Society of Japan, (MRS-J) 20, 21-24, (1996).
-
(1996)
Transaction of the Materials Research Society of Japan
, vol.20
, pp. 21-24
-
-
Mizuguchi, H.1
-
13
-
-
0033546726
-
A novel vaccine delivery system using immunopotentiating fusogenic liposomes
-
Hayashi, A., et al.: A novel vaccine delivery system using immunopotentiating fusogenic liposomes. Biochem. Biophys. Res. Commun., 261: 824-828 (1999).
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.261
, pp. 824-828
-
-
Hayashi, A.1
-
14
-
-
0034037160
-
Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway
-
Nakanishi, T., et al.: Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway. Eur. J. Immunol., 30: 1740-1747 (2000).
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1740-1747
-
-
Nakanishi, T.1
-
15
-
-
0030047629
-
Application of fusogenic liposomes containing fragment A of diphtheria toxin to cancer therapy
-
Mizuguchi, H., et al.: Application of fusogenic liposomes containing fragment A of diphtheria toxin to cancer therapy. Br. J. Cancer, 73: 472-476 (1996).
-
(1996)
Br. J. Cancer
, vol.73
, pp. 472-476
-
-
Mizuguchi, H.1
-
16
-
-
0030045159
-
Intratumor administration of fusogenic liposomes containing fragment A of diphtheria toxin suppresses tumor growth
-
Mizuguchi, H., et al.: Intratumor administration of fusogenic liposomes containing fragment A of diphtheria toxin suppresses tumor growth. Cancer Lett., 100: 63-69 (1996).
-
(1996)
Cancer Lett.
, vol.100
, pp. 63-69
-
-
Mizuguchi, H.1
-
17
-
-
0033844079
-
Growth inhibition of human leukemia HL-60 cells by an antisense phosphodiester oligonucleotide encapsulated into fusogenic liposomes
-
Kondoh, M., et al.: Growth inhibition of human leukemia HL-60 cells by an antisense phosphodiester oligonucleotide encapsulated into fusogenic liposomes. Biol. Pharm. Bull., 23: 1011-1013 (2000).
-
(2000)
Biol. Pharm. Bull.
, vol.23
, pp. 1011-1013
-
-
Kondoh, M.1
-
18
-
-
0027496645
-
Stepwise dismantling of adenovirus 2 during entry into cells
-
Greber, U. F., et al.: Stepwise dismantling of adenovirus 2 during entry into cells. Cell, 75: 477-486 (1993).
-
(1993)
Cell
, vol.75
, pp. 477-486
-
-
Greber, U.F.1
-
19
-
-
0030956036
-
Cytoplasmic gene expression system enhances the efficiency of cationic liposome-mediated in vivo gene transfer into mouse brain
-
Mizuguchi, H., et al.: Cytoplasmic gene expression system enhances the efficiency of cationic liposome-mediated in vivo gene transfer into mouse brain. Biochem. Biophys. Res. Commun., 234: 15-18 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.234
, pp. 15-18
-
-
Mizuguchi, H.1
-
20
-
-
0037459047
-
A nobel T7 system utilizing mRNA coding for T7 RNA polymerase
-
Nakano, R., et al.: A nobel T7 system utilizing mRNA coding for T7 RNA polymerase. Biochem. Biophys. Res. Commun., 301: 974-978 (2003).
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.301
, pp. 974-978
-
-
Nakano, R.1
-
21
-
-
0004079360
-
-
ed. Nouer L. (CRC, Boca Raton, FL)
-
Nouer, L.: in Heat Shock Response, ed. Nouer, L. (CRC, Boca Raton, FL), pp. 167-220 (1991).
-
(1991)
Heat Shock Response
, pp. 167-220
-
-
Nouer, L.1
-
22
-
-
0019884568
-
Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids
-
Lee, F., Mulligan, R., Berg, P. and Ringold, G.: Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids. Nature, 294: 228-232 (1981).
-
(1981)
Nature
, vol.294
, pp. 228-232
-
-
Lee, F.1
Mulligan, R.2
Berg, P.3
Ringold, G.4
-
23
-
-
0019405375
-
Hormone-responsive expression of an endogenous proviral gene of mouse mammary tumor virus after molecular cloning and gene transfer into cultured cells
-
Hynes, N. E., Kennedy, N., Rahmsdorf, U. and Groner, B.: Hormone-responsive expression of an endogenous proviral gene of mouse mammary tumor virus after molecular cloning and gene transfer into cultured cells. Proc. Natl. Acad. Sci. USA, 78: 2038-2042 (1981).
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 2038-2042
-
-
Hynes, N.E.1
Kennedy, N.2
Rahmsdorf, U.3
Groner, B.4
-
24
-
-
0023640459
-
Oestrogen and glucocorticoid responsive elements are closely related but distinct
-
Klock, G., Strahle, U. and Schutz, G.: Oestrogen and glucocorticoid responsive elements are closely related but distinct. Nature, 329: 734-736 (1987).
-
(1987)
Nature
, vol.329
, pp. 734-736
-
-
Klock, G.1
Strahle, U.2
Schutz, G.3
-
25
-
-
0024332387
-
Highly inducible expression from vectors containing multiple GRE's in CHO cells overexpressing the glucocorticoid receptor
-
Israel-D. I., Kaufman-R. J.: Highly inducible expression from vectors containing multiple GRE's in CHO cells overexpressing the glucocorticoid receptor. Nucleic-Acids-Res., 17: 4589-4604 (1989).
-
(1989)
Nucleic-Acids-Res.
, vol.17
, pp. 4589-4604
-
-
Israel-D., I.1
Kaufman-R., J.2
-
26
-
-
0020328232
-
The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells
-
Mayo, K. E., Warren, R. and Palmiter, R. D.: The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells. Cell, 29: 99-108 (1982).
-
(1982)
Cell
, vol.29
, pp. 99-108
-
-
Mayo, K.E.1
Warren, R.2
Palmiter, R.D.3
-
27
-
-
0020083107
-
Regulation of metallothionein-thymidine kinase fusion plasmids injected into mouse eggs
-
Brinster, R. L., Chen, H. Y., Warren, R., Sarthy, A. and Palmiter, R. D.: Regulation of metallothionein-thymidine kinase fusion plasmids injected into mouse eggs. Nature, 296: 39-42 (1982).
-
(1982)
Nature
, vol.296
, pp. 39-42
-
-
Brinster, R.L.1
Chen, H.Y.2
Warren, R.3
Sarthy, A.4
Palmiter, R.D.5
-
28
-
-
0021986710
-
Building a metal-responsive promoter with synthetic regulatory elements
-
Searle, P. F., Stuart, G. W. and Palmiter, R. D.: Building a metal-responsive promoter with synthetic regulatory elements. Mol. Cell. Biol., 5: 1480-1489 (1985).
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 1480-1489
-
-
Searle, P.F.1
Stuart, G.W.2
Palmiter, R.D.3
-
29
-
-
0029043548
-
Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression
-
Anton, M. and Graham, F. L.: Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression. J. Virol., 69: 4600-4606 (1995).
-
(1995)
J. Virol.
, vol.69
, pp. 4600-4606
-
-
Anton, M.1
Graham, F.L.2
-
30
-
-
0028799961
-
Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase
-
Kanegae, Y., Lee, G., Sato, Y., Tanaka, M., Nakai, M., Sakaki, T., Sugano, S. and Saito, I.: Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase. Nucleic. Acids. Res., 23, 3816-3821 (1995).
-
(1995)
Nucleic. Acids. Res.
, vol.23
, pp. 3816-3821
-
-
Kanegae, Y.1
Lee, G.2
Sato, Y.3
Tanaka, M.4
Nakai, M.5
Sakaki, T.6
Sugano, S.7
Saito, I.8
-
31
-
-
0026756197
-
Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells
-
Fukushige, S. and Sauer, B.: Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA, 89: 7905-7909 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7905-7909
-
-
Fukushige, S.1
Sauer, B.2
-
32
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen, M. and Bujard, H.: Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA, 89, 5547-5551 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
33
-
-
0012954146
-
in Protein-Nucleic Acid Interaction, Topics in Molecular and Structural Biology
-
eds. Saenger, W. Heinemann, U. Macmillan, London
-
Hillen, W. and Wissmann, A.: in Protein-Nucleic Acid Interaction, Topics in Molecular and Structural Biology, eds. Saenger, W. and Heinemann, U., Macmillan, London, Vol. 10, pp. 143-162 (1989).
-
(1989)
, vol.10
, pp. 143-162
-
-
Hillen, W.1
Wissmann, A.2
-
34
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
Gossen, M., et al.: Transcriptional activation by tetracyclines in mammalian cells. Science, 268: 1766-1769 (1995).
-
(1995)
Science
, vol.268
, pp. 1766-1769
-
-
Gossen, M.1
-
35
-
-
0035061224
-
Tetracycline-regulatable adenovirus vectors: pharmacologic properties and clinical potential
-
Nakagawa, S., et al.: Tetracycline-regulatable adenovirus vectors: pharmacologic properties and clinical potential. European J. Pharmaceutical Sciences, 13: 53-60 (2002).
-
(2002)
European J. Pharmaceutical Sciences
, vol.13
, pp. 53-60
-
-
Nakagawa, S.1
|