Cardiac-specific Nkx2.5 homeodomain: Conformational stability and specific DNA binding of Nkx2.5(C56S)

Biochemistry

Volumn 44, Issue 37, 2005, Pages 12480-12490

  Fodor, Elfrieda ^a   Mack, James W ^a,b   Maeng, Jin Soo ^a,b   Ju, Jeong Ho ^a   Lee, Hyun Sook ^a   Gruschus, James M ^a   Ferretti, James A ^a   Ginsburg, Ann ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b HOWARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; CARDIOLOGY; CONFORMATIONS; DIFFERENTIAL SCANNING CALORIMETRY; STOICHIOMETRY; THERMOANALYSIS; THERMODYNAMICS;

BINDING REACTION; CIRCULAR DICHROISM; CONFORMATIONAL STABILITY; THERMAL UNFOLDING;

DNA;

DNA; HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR NKX2.5; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DNA BINDING; DROSOPHILA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STABILITY; THERMAL ANALYSIS; THERMODYNAMICS; TISSUE SPECIFICITY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CALORIMETRY; DNA; DROSOPHILA; DROSOPHILA PROTEINS; HOMEODOMAIN PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYOCARDIUM; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; RESTRICTION MAPPING; THERMODYNAMICS; TRANSCRIPTION FACTORS;

EID: 24944574310     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050835s     Document Type: Article

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