Nonnucleoside HIV-1 reverse-transcriptase inhibitors, part 5.1) synthesis and anti-HIV-1 activity of novel 6-naphthylthio HEPT analogues

Chemical and Pharmaceutical Bulletin

Volumn 53, Issue 8, 2005, Pages 886-892

  Sun, Guang Fu ^a   Chen, Xu Xiang ^b   Chen, Fen Er ^a   Wang, Yue Ping ^a   De Clercq, Erik ^c   Balzarini, Jan ^c   Pannecouque, Christophe ^c  

^a FUDAN UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

1 (2 hydroxyethoxy)methyl 6 (phenylthio) thymine (HEPT) analogue; HIV 1; Mutation; Nonnucleoside reverse transcriptase inhibitor

Indexed keywords

RNA DIRECTED DNA POLYMERASE INHIBITOR; THYMINE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

HIV-1 REVERSE TRANSCRIPTASE; MAGNETIC RESONANCE SPECTROSCOPY; REVERSE TRANSCRIPTASE INHIBITORS; SPECTROPHOTOMETRY, INFRARED; THYMINE;

EID: 24944539873     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.53.886     Document Type: Article

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