-
1
-
-
0035487579
-
The Daily Pattern of Heart Rate, Body Temperature, and Locomotor Activity in Guinea Pigs
-
Akita, M., Ishii, K., Kuwahara, M. and Tsubone, H. (2001): The Daily Pattern of Heart Rate, Body Temperature, and Locomotor Activity in Guinea Pigs. Exp. Anim., 50, 409-415.
-
(2001)
Exp. Anim.
, vol.50
, pp. 409-415
-
-
Akita, M.1
Ishii, K.2
Kuwahara, M.3
Tsubone, H.4
-
2
-
-
0001127258
-
An analysis of the time-relations of electrocardiograms
-
Bazett, H.C. (1920): An analysis of the time-relations of electrocardiograms. Heart, 7, 353-370.
-
(1920)
Heart
, vol.7
, pp. 353-370
-
-
Bazett, H.C.1
-
3
-
-
0036067677
-
Effects of sildenafil on cardiac repolarization
-
Chiang, C.E., Luk, H.N., Wang, T.M. and Ding, P.Y. (2002): Effects of sildenafil on cardiac repolarization. Cardiovasc. Res., 55, 290-299.
-
(2002)
Cardiovasc. Res.
, vol.55
, pp. 290-299
-
-
Chiang, C.E.1
Luk, H.N.2
Wang, T.M.3
Ding, P.Y.4
-
4
-
-
0033061972
-
Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs
-
De Abajo, F.J. and Rodriguez, L.A. (1999): Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs. Br. J. Clin. Pharmacol., 47, 307-313.
-
(1999)
Br. J. Clin. Pharmacol.
, vol.47
, pp. 307-313
-
-
De Abajo, F.J.1
Rodriguez, L.A.2
-
5
-
-
0035985179
-
In vivo measurement of QT prolongation, dispersion and arrhythmogenesis: Application to the preclinical cardiovascular safety pharmacology of a new chemical entity
-
De Clerck, F., van de Water, A., D'Aubioul, J., Lu, H.R., van Rossem, K., Hermans, A. and van Ammel, K. (2002): In vivo measurement of QT prolongation, dispersion and arrhythmogenesis: Application to the preclinical cardiovascular safety pharmacology of a new chemical entity. Fundam. Clin. Pharmacol., 16, 125-140.
-
(2002)
Fundam. Clin. Pharmacol.
, vol.16
, pp. 125-140
-
-
De Clerck, F.1
Van De Water, A.2
D'Aubioul, J.3
Lu, H.R.4
Van Rossem, K.5
Hermans, A.6
Van Ammel, K.7
-
6
-
-
0033935925
-
Corrected QT interval prolongation associated with intravenous haloperidol in acute coronary syndromes
-
Douglas, P.H. and Block, P.C. (2000): Corrected QT interval prolongation associated with intravenous haloperidol in acute coronary syndromes. Catheter. Cardiovasc. Interv., 50, 352-355.
-
(2000)
Catheter. Cardiovasc. Interv.
, vol.50
, pp. 352-355
-
-
Douglas, P.H.1
Block, P.C.2
-
7
-
-
0036150473
-
Proarrhythmic effects of intravenous quinidine, amiodarone, d-sotalol, and almokalant in the anesthetized rabbit model of Torsade de Pointes
-
Farkas, A., Lepran, I. and Papp, J.G. (2002): Proarrhythmic effects of intravenous quinidine, amiodarone, d-sotalol, and almokalant in the anesthetized rabbit model of Torsade de Pointes. J. Cardiovasc. Pharmacol., 39, 287-297.
-
(2002)
J. Cardiovasc. Pharmacol.
, vol.39
, pp. 287-297
-
-
Farkas, A.1
Lepran, I.2
Papp, J.G.3
-
8
-
-
84980098899
-
Die Systolendauer im Elektrokardiogramm bei normaln Menschen und bei Herzkranken
-
Fridericia, L.S. (1920): Die Systolendauer im Elektrokardiogramm bei normaln Menschen und bei Herzkranken. Acta. Med. Scan., 53, 469.
-
(1920)
Acta Med. Scan.
, vol.53
, pp. 469
-
-
Fridericia, L.S.1
-
10
-
-
0346399929
-
QT and RR Intervals in Conscious and Anesthetized Guinea Pigs with Highly Varying RR Intervals and Given QTc-Lengthening Test Articles
-
Hamlin, R.L., Kijtawornrat, A., Keene, B.W. and Hamlin, D.M. (2003): QT and RR Intervals in Conscious and Anesthetized Guinea Pigs with Highly Varying RR Intervals and Given QTc-Lengthening Test Articles. Toxicol. Sci., 76, 437-442.
-
(2003)
Toxicol. Sci.
, vol.76
, pp. 437-442
-
-
Hamlin, R.L.1
Kijtawornrat, A.2
Keene, B.W.3
Hamlin, D.M.4
-
11
-
-
24944482778
-
Long-term Observation of Electrocardiographic Changes in Thyroidectomized Male Rats
-
Harada, T., Hassimoto, M., Mitsui, T., Kaga, N., Obata, M. and Mochizuki, H. (2002): Long-term Observation of Electrocardiographic Changes in Thyroidectomized Male Rats. Adv. Anim. Cardiol., 35, 13-24.
-
(2002)
Adv. Anim. Cardiol.
, vol.35
, pp. 13-24
-
-
Harada, T.1
Hassimoto, M.2
Mitsui, T.3
Kaga, N.4
Obata, M.5
Mochizuki, H.6
-
12
-
-
2142695682
-
Torsade de pointes associated with the administration of intravenous haloperidol: A review of the literature and practical guidelines for use
-
Hassaballa, H.A. and Balk, R.A. (2003): Torsade de pointes associated with the administration of intravenous haloperidol: A review of the literature and practical guidelines for use. Expert. Opin. Drug. Saf., 2, 543-547.
-
(2003)
Expert. Opin. Drug. Saf.
, vol.2
, pp. 543-547
-
-
Hassaballa, H.A.1
Balk, R.A.2
-
13
-
-
0035012236
-
The association between intravenous haloperidol and prolonged QT interval
-
Hatta, K., Takahashi, T., Nakamura, H., Yamashiro, H., Asukai, N., Matsuzaki, I. and Yonezawa, Y. (2001): The association between intravenous haloperidol and prolonged QT interval. J. Clin. Psychopharmacol., 21, 257-261.
-
(2001)
J. Clin. Psychopharmacol.
, vol.21
, pp. 257-261
-
-
Hatta, K.1
Takahashi, T.2
Nakamura, H.3
Yamashiro, H.4
Asukai, N.5
Matsuzaki, I.6
Yonezawa, Y.7
-
14
-
-
0028578687
-
Relationship between QaT and RR intervals in rats, guinea pigs, rabbits, and primates
-
Hayes, E., Pugsley, K.M., Penz, P.W., Adaikan, G. and Walker, J.M. (1994): Relationship between QaT and RR intervals in rats, guinea pigs, rabbits, and primates. J. Pharmacol. Toxicol. Methods, 32, 201-207.
-
(1994)
J. Pharmacol. Toxicol. Methods
, vol.32
, pp. 201-207
-
-
Hayes, E.1
Pugsley, K.M.2
Penz, P.W.3
Adaikan, G.4
Walker, J.M.5
-
15
-
-
0031811044
-
Proarrhythmia associated with cisapride in children
-
Hill, S.L., Evangelista, J.K., Pizzi, A.M., Mobassaleh, M., Fulton, D.R. and Berul, C.I. (1998): Proarrhythmia associated with cisapride in children. Pediatrics, 101, 1053-1056.
-
(1998)
Pediatrics
, vol.101
, pp. 1053-1056
-
-
Hill, S.L.1
Evangelista, J.K.2
Pizzi, A.M.3
Mobassaleh, M.4
Fulton, D.R.5
Berul, C.I.6
-
16
-
-
0036015373
-
Development of telemetry system in the common marmoset -Cardiovascular effects of astemizole and nicardipine
-
Horii, I., Kito, G., Hamada, T., Jikuzono, T., Kobayashi, K. and Hashimoto, K. (2002): Development of telemetry system in the common marmoset -Cardiovascular effects of astemizole and nicardipine. J. Toxicol. Sci., 27, 123-130.
-
(2002)
J. Toxicol. Sci.
, vol.27
, pp. 123-130
-
-
Horii, I.1
Kito, G.2
Hamada, T.3
Jikuzono, T.4
Kobayashi, K.5
Hashimoto, K.6
-
17
-
-
0028803399
-
The association between intravenous haloperidol and Torsades de Pointes. Three cases and a literature review
-
Hunt, N. and Stern, T.A. (1995): The association between intravenous haloperidol and Torsades de Pointes. Three cases and a literature review. Psychosomatics, 36, 541-549.
-
(1995)
Psychosomatics
, vol.36
, pp. 541-549
-
-
Hunt, N.1
Stern, T.A.2
-
18
-
-
48849109399
-
The t-test with F-test for homogeneity of variance. Significance test of difference between the two population means (standard deviations unknown, two-sided)
-
JIS (1965): The t-test with F-test for homogeneity of variance. Significance test of difference between the two population means (standard deviations unknown, two-sided). Japanese Industry Standard Z9049.
-
(1965)
Japanese Industry Standard Z9049
-
-
-
19
-
-
0034845983
-
4 Receptor Agonists, Cisapride and Mosapride Citrate on Electrocardiogram in Anaesthetized Rats and Guinea-Pigs and Conscious Cats
-
4 Receptor Agonists, Cisapride and Mosapride Citrate on Electrocardiogram in Anaesthetized Rats and Guinea-Pigs and Conscious Cats. Pharmacol. Toxicol., 89, 96-103.
-
(2001)
Pharmacol. Toxicol.
, vol.89
, pp. 96-103
-
-
Kii, Y.1
Nakatsuji, K.2
Nose, I.3
Yabuuchi, M.4
Mizuki, Y.5
Ito, T.6
-
20
-
-
0031432750
-
QT Corrected for Heart Rate and Relation between QT and RR Intervals in Beagle Dogs
-
Matsunaga, T., Mitsui, T., Harada, T., Inokuma, M., Murano, H. and Shibutani, Y. (1997): QT Corrected for Heart Rate and Relation Between QT and RR Intervals in Beagle Dogs. J. Pharmacol. Toxicol. Methods., 38, 201-209.
-
(1997)
J. Pharmacol. Toxicol. Methods
, vol.38
, pp. 201-209
-
-
Matsunaga, T.1
Mitsui, T.2
Harada, T.3
Inokuma, M.4
Murano, H.5
Shibutani, Y.6
-
21
-
-
0027457330
-
Prolongation of the corrected QT and torsades de pointes cardiac arrhythmia associated with intravenous haloperidol in the medically ill
-
Metzger, E. and Friedman, R. (1993): Prolongation of the corrected QT and torsades de pointes cardiac arrhythmia associated with intravenous haloperidol in the medically ill. J. Clin. Psychopharmacol., 13, 128-132.
-
(1993)
J. Clin. Psychopharmacol.
, vol.13
, pp. 128-132
-
-
Metzger, E.1
Friedman, R.2
-
22
-
-
0035732087
-
Quantitative relationship between myocardial concentration of tacrolimus and QT prolongation in guinea pigs: Pharmacokinetic/pharmacodynamic model incorporating a site of adverse effect
-
Minematsu, T., Ohtani, H., Yamada, Y., Sawada, Y., Sato, H. and Iga, T. (2001): Quantitative relationship between myocardial concentration of tacrolimus and QT prolongation in guinea pigs: Pharmacokinetic/pharmacodynamic model incorporating a site of adverse effect. J. Pharmacokinet. Pharmacodyn., 28, 533-554.
-
(2001)
J. Pharmacokinet. Pharmacodyn.
, vol.28
, pp. 533-554
-
-
Minematsu, T.1
Ohtani, H.2
Yamada, Y.3
Sawada, Y.4
Sato, H.5
Iga, T.6
-
23
-
-
0034213745
-
+ channel diversity in the mammalian myocardium
-
+ channel diversity in the mammalian myocardium. J. Physiol., 525, 285-298.
-
(2000)
J. Physiol.
, vol.525
, pp. 285-298
-
-
Nerbonne, J.M.1
-
24
-
-
0032788779
-
Effects of terfenadine, astemizole and epinastine on electrocardiogram in conscious cynomolgus monkeys
-
Ohmura, T., Chachin, M., Tarui, S., Nagakura, A., Igarashi, T., Ikeda, H., Ikegami, K., Kitagawa, H. and Uchida, S. (1999): Effects of terfenadine, astemizole and epinastine on electrocardiogram in conscious cynomolgus monkeys. Eur. J. Pharmacol., 378, 169-175.
-
(1999)
Eur. J. Pharmacol.
, vol.378
, pp. 169-175
-
-
Ohmura, T.1
Chachin, M.2
Tarui, S.3
Nagakura, A.4
Igarashi, T.5
Ikeda, H.6
Ikegami, K.7
Kitagawa, H.8
Uchida, S.9
-
25
-
-
0034989198
-
A comparative pharmacodynamic study of the arrhythmogenicity of antidepressants, fluvoxamine and imipramine, in guinea pigs
-
Ohtani, H., Odagiri, Y., Sato, H., Sawada, Y. and Iga, T. (2001): A comparative pharmacodynamic study of the arrhythmogenicity of antidepressants, fluvoxamine and imipramine, in guinea pigs. Biol. Pharm. Bull., 24, 550-554.
-
(2001)
Biol. Pharm. Bull.
, vol.24
, pp. 550-554
-
-
Ohtani, H.1
Odagiri, Y.2
Sato, H.3
Sawada, Y.4
Iga, T.5
-
26
-
-
0037625909
-
QT interval prolongation and cardiac risk assessment for novel drugs
-
Picard, S. and Lacroix, P. (2003): QT interval prolongation and cardiac risk assessment for novel drugs. Curr. Opin. Investig. Drugs., 4, 303-308.
-
(2003)
Curr. Opin. Investig. Drugs
, vol.4
, pp. 303-308
-
-
Picard, S.1
Lacroix, P.2
-
27
-
-
0036039326
-
The significance of QT interval in drug development
-
Shah, R.R. (2002): The significance of QT interval in drug development. Br. J. Clin. Pharmacol., 54, 188-202.
-
(2002)
Br. J. Clin. Pharmacol.
, vol.54
, pp. 188-202
-
-
Shah, R.R.1
-
28
-
-
24944447230
-
QT Interval Prolongation: Project for Database Construction, 4) Overview of anesthetized dog studies
-
Tashibu, H. (2004): QT Interval Prolongation: Project for Database Construction, 4) Overview of anesthetized dog studies. J. Toxicol. Sci., 29, 365.
-
(2004)
J. Toxicol. Sci.
, vol.29
, pp. 365
-
-
Tashibu, H.1
-
29
-
-
0035200703
-
The effect of intravenous haloperidol on QT interval dispersion in critically ill patients: Comparison with QT interval prolongation for assessment of risk of Torsades de Pointes
-
Tisdale, J.E., Rasty, S., Padhi, I.D., Sharma, N.D. and Rosman, H. (2001): The effect of intravenous haloperidol on QT interval dispersion in critically ill patients: Comparison with QT interval prolongation for assessment of risk of Torsades de Pointes. J. Clin. Pharmacol., 41, 1310-1318.
-
(2001)
J. Clin. Pharmacol.
, vol.41
, pp. 1310-1318
-
-
Tisdale, J.E.1
Rasty, S.2
Padhi, I.D.3
Sharma, N.D.4
Rosman, H.5
-
30
-
-
24944522058
-
QT interval prolongation: Project for database construction, 2) Overview of dog telemetry studies
-
Toyoshima, S. (2004): QT interval prolongation: Project for database construction, 2) Overview of dog telemetry studies. J. Toxicol. Sci., 29, 363.
-
(2004)
J. Toxicol. Sci.
, vol.29
, pp. 363
-
-
Toyoshima, S.1
-
31
-
-
0000576729
-
The significance of the difference between two means when the population variances are unequal
-
Welch, B.L. (1938): The significance of the difference between two means when the population variances are unequal. Biometrika, 29, 350-362.
-
(1938)
Biometrika
, vol.29
, pp. 350-362
-
-
Welch, B.L.1
-
32
-
-
0027474601
-
Mechanism of the cardiotoxic actions of terfenadine
-
Woosley, R.L., Chen, Y., Freiman, J.P. and Gillis, R.A. (1993): Mechanism of the cardiotoxic actions of terfenadine. JAMA, 269, 1532-1536.
-
(1993)
JAMA
, vol.269
, pp. 1532-1536
-
-
Woosley, R.L.1
Chen, Y.2
Freiman, J.P.3
Gillis, R.A.4
-
33
-
-
0036023350
-
Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model
-
Yoshida, H., Sugiyama, A., Satoh, Y., Ishida, Y., Yoneyama, M., Kugiyama, K. and Hashimoto, K. (2002): Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model. Circ. J., 66, 758-762.
-
(2002)
Circ. J.
, vol.66
, pp. 758-762
-
-
Yoshida, H.1
Sugiyama, A.2
Satoh, Y.3
Ishida, Y.4
Yoneyama, M.5
Kugiyama, K.6
Hashimoto, K.7
|