-
1
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
2
-
-
0036518287
-
Mouse and human dendritic cell subtypes
-
Shortman, K., and Y. J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2: 151-161.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 151-161
-
-
Shortman, K.1
Liu, Y.J.2
-
3
-
-
0035838979
-
Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity
-
Liu, Y. J. 2001. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106: 259-262.
-
(2001)
Cell
, vol.106
, pp. 259-262
-
-
Liu, Y.J.1
-
5
-
-
2442494120
-
Autoimmunity through cytokine-induced dendritic cell activation
-
Banchereau, J., V. Pascual, and A. K. Palucka. 2004. Autoimmunity through cytokine-induced dendritic cell activation. Immunity 20: 539-550.
-
(2004)
Immunity
, vol.20
, pp. 539-550
-
-
Banchereau, J.1
Pascual, V.2
Palucka, A.K.3
-
6
-
-
0036906526
-
Langerhans cells renew in the skin throughout life under steady-state conditions
-
Merad, M., M. G. Manz, H. Karsunky, A. Wagers, W. Peters, I. Charo, I. L. Weissman, J. G. Cyster, and E. G. Engleman. 2002. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat. Immunol. 3: 1135-1141.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1135-1141
-
-
Merad, M.1
Manz, M.G.2
Karsunky, H.3
Wagers, A.4
Peters, W.5
Charo, I.6
Weissman, I.L.7
Cyster, J.G.8
Engleman, E.G.9
-
7
-
-
0038406789
-
Biology of hematopoietic stem cells and progenitors: Implications for clinical application
-
Kondo, M., A. J. Wagers, M. G. Manz, S. S. Prohaska, D. C. Scherer, G. F. Beilhack, J. A. Shizuru, and I. L. Weissman. 2003. Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu. Rev. Immunol. 21: 759-806.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 759-806
-
-
Kondo, M.1
Wagers, A.J.2
Manz, M.G.3
Prohaska, S.S.4
Scherer, D.C.5
Beilhack, G.F.6
Shizuru, J.A.7
Weissman, I.L.8
-
8
-
-
0032519768
-
c-kit ligand and Flt3 ligand: Stem/progenitor cell factors with overlapping yet distinct activities
-
Lyman, S. D., and S. E. Jacobsen. 1998. c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities. Blood 91: 1101-1134.
-
(1998)
Blood
, vol.91
, pp. 1101-1134
-
-
Lyman, S.D.1
Jacobsen, S.E.2
-
9
-
-
0034749999
-
+ stem cell compartment is accompanied by loss of self-renewal capacity
-
+ stem cell compartment is accompanied by loss of self-renewal capacity. Immunity 15: 659-669.
-
(2001)
Immunity
, vol.15
, pp. 659-669
-
-
Adolfsson, J.1
Borge, O.J.2
Bryder, D.3
Theilgaard-Monch, K.4
Astrand-Grundstrom, I.5
Sitnicka, E.6
Sasaki, Y.7
Jacobsen, S.E.8
-
10
-
-
0035807964
-
Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
-
Christensen, J. L., and I. L. Weissman. 2001. Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells. Proc. Natl. Acad. Sci. USA 98: 14541-14546.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14541-14546
-
-
Christensen, J.L.1
Weissman, I.L.2
-
11
-
-
0036797682
-
Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool
-
Sitnicka, E., D. Bryder, K. Theilgaard-Monch, N. Buza-Vidas, J. Adolfsson, and S. E. Jacobsen. 2002. Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool. Immunity 17: 463-472.
-
(2002)
Immunity
, vol.17
, pp. 463-472
-
-
Sitnicka, E.1
Bryder, D.2
Theilgaard-Monch, K.3
Buza-Vidas, N.4
Adolfsson, J.5
Jacobsen, S.E.6
-
13
-
-
0041660895
-
The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3
-
D'Amico, A., and L. Wu. 2003. The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3. J. Exp. Med. 198: 293-303.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 293-303
-
-
D'Amico, A.1
Wu, L.2
-
14
-
-
0034332450
-
Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures
-
Brasel, K., T. De Smedt, J. L. Smith, and C. R. Maliszewski. 2000. Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures. Blood 96: 3029-3039.
-
(2000)
Blood
, vol.96
, pp. 3029-3039
-
-
Brasel, K.1
De Smedt, T.2
Smith, J.L.3
Maliszewski, C.R.4
-
15
-
-
0036534871
-
The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor
-
Gilliet, M., A. Boonstra, C. Paturel, S. Antonenko, X. L. Xu, G. Trinchieri, A. O'Garra, and Y. J. Liu. 2002. The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 195: 953-958.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 953-958
-
-
Gilliet, M.1
Boonstra, A.2
Paturel, C.3
Antonenko, S.4
Xu, X.L.5
Trinchieri, G.6
O'Garra, A.7
Liu, Y.J.8
-
16
-
-
0034210658
-
Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells
-
McKenna, H. J., K. L. Stocking, R. E. Miller, K. Brasel, T. De Smedt, E. Maraskovsky, C. R. Maliszewski, D. H. Lynch, J. Smith, B. Pulendran, et al. 2000. Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells. Blood 95: 3489-3497.
-
(2000)
Blood
, vol.95
, pp. 3489-3497
-
-
McKenna, H.J.1
Stocking, K.L.2
Miller, R.E.3
Brasel, K.4
De Smedt, T.5
Maraskovsky, E.6
Maliszewski, C.R.7
Lynch, D.H.8
Smith, J.9
Pulendran, B.10
-
17
-
-
0347480225
-
STAT3 is required for Flt3L-dependent dendritic cell differentiation
-
Laouar, Y., T. Welte, X. Y. Fu, and R. A. Flavell. 2003. STAT3 is required for Flt3L-dependent dendritic cell differentiation. Immunity 19: 903-912.
-
(2003)
Immunity
, vol.19
, pp. 903-912
-
-
Laouar, Y.1
Welte, T.2
Fu, X.Y.3
Flavell, R.A.4
-
18
-
-
0029661945
-
Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: Multiple dendritic cell subpopulations identified
-
Maraskovsky, E., K. Brasel, M. Teepe, E. R. Roux, S. D. Lyman, K. Shortman, and H. J. McKenna. 1996. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. J. Exp. Med. 184: 1953-1962.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1953-1962
-
-
Maraskovsky, E.1
Brasel, K.2
Teepe, M.3
Roux, E.R.4
Lyman, S.D.5
Shortman, K.6
McKenna, H.J.7
-
19
-
-
0031225999
-
Developmental pathways of dendritic cells in vivo: Distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice
-
Pulendran, B., J. Lingappa, M. K. Kennedy, J. Smith, M. Teepe, A. Rudensky, C. R. Maliszewski, and E. Maraskovsky. 1997. Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice. J. Immunol. 159: 2222-2231.
-
(1997)
J. Immunol.
, vol.159
, pp. 2222-2231
-
-
Pulendran, B.1
Lingappa, J.2
Kennedy, M.K.3
Smith, J.4
Teepe, M.5
Rudensky, A.6
Maliszewski, C.R.7
Maraskovsky, E.8
-
20
-
-
0037085754
-
Effects of administration of progenipoietin 1, Flt-3 ligand, granulocyte colony-stimulating factor, and pegylated granulocyte-macrophage colony-stimulating factor on dendritic cell subsets in mice
-
O'Keeffe, M., H. Hochrein, D. Vremec, J. Pooley, R. Evans, S. Woulfe, and K. Shortman. 2002. Effects of administration of progenipoietin 1, Flt-3 ligand, granulocyte colony-stimulating factor, and pegylated granulocyte-macrophage colony-stimulating factor on dendritic cell subsets in mice. Blood 99: 2122-2130.
-
(2002)
Blood
, vol.99
, pp. 2122-2130
-
-
O'Keeffe, M.1
Hochrein, H.2
Vremec, D.3
Pooley, J.4
Evans, R.5
Woulfe, S.6
Shortman, K.7
-
21
-
-
0035895048
-
Isolation and characterization of plasmacytoid dendritic cells from Flt3 ligand and granulocyte-macrophage colony-stimulating factor-treated mice
-
Bjorck, P. 2001. Isolation and characterization of plasmacytoid dendritic cells from Flt3 ligand and granulocyte-macrophage colony-stimulating factor-treated mice. Blood 98: 3520-3526.
-
(2001)
Blood
, vol.98
, pp. 3520-3526
-
-
Bjorck, P.1
-
22
-
-
0034254472
-
In vivo generation of human dendritic cell subsets by Flt3 ligand
-
Maraskovsky, E., E. Daro, E. Roux, M. Teepe, C. R. Maliszewski, J. Hoek, D. Caron, M. E. Lebsack, and H. J. McKenna. 2000. In vivo generation of human dendritic cell subsets by Flt3 ligand. Blood 96: 878-884.
-
(2000)
Blood
, vol.96
, pp. 878-884
-
-
Maraskovsky, E.1
Daro, E.2
Roux, E.3
Teepe, M.4
Maliszewski, C.R.5
Hoek, J.6
Caron, D.7
Lebsack, M.E.8
McKenna, H.J.9
-
23
-
-
0034235748
-
Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo
-
Pulendran, B., J. Banchereau, S. Burkeholder, E. Kraus, E. Guinet, C. Chalouni, D. Caron, C. Maliszewski, J. Davoust, J. Fay, and K. Palucka. 2000. Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo. J. Immunol. 165: 566-572.
-
(2000)
J. Immunol.
, vol.165
, pp. 566-572
-
-
Pulendran, B.1
Banchereau, J.2
Burkeholder, S.3
Kraus, E.4
Guinet, E.5
Chalouni, C.6
Caron, D.7
Maliszewski, C.8
Davoust, J.9
Fay, J.10
Palucka, K.11
-
24
-
-
2942516628
-
Modulating vaccine responses with dendritic cells and Toll-like receptors
-
Pulendran, B. 2004. Modulating vaccine responses with dendritic cells and Toll-like receptors. Immunol. Rev. 199: 227-250.
-
(2004)
Immunol. Rev.
, vol.199
, pp. 227-250
-
-
Pulendran, B.1
-
25
-
-
0037783433
-
A model of APL with FLT3 mutation is responsive to retinoic acid and a receptor tyrosine kinase inhibitor, SU11657
-
Sohal, J., V. T. Phan, P. V. Chan, E. M. Davis, B. Patel, L. M. Kelly, T. J. Abrams, A. M. O'Farrell, D. G. Gilliland, M. M. Le Beau, and S. C. Kogan. 2003. A model of APL with FLT3 mutation is responsive to retinoic acid and a receptor tyrosine kinase inhibitor, SU11657. Blood 101: 3188-3197.
-
(2003)
Blood
, vol.101
, pp. 3188-3197
-
-
Sohal, J.1
Phan, V.T.2
Chan, P.V.3
Davis, E.M.4
Patel, B.5
Kelly, L.M.6
Abrams, T.J.7
O'Farrell, A.M.8
Gilliland, D.G.9
Le Beau, M.M.10
Kogan, S.C.11
-
26
-
-
3142515944
-
Complete remission of TEL-PDGFRB-induced myeloproliferative disease in mice by receptor tyrosine kinase inhibitor SU11657
-
Cain, J. A., J. L. Grisolano, A. D. Laird, and M. H. Tomasson. 2004. Complete remission of TEL-PDGFRB-induced myeloproliferative disease in mice by receptor tyrosine kinase inhibitor SU11657. Blood 104: 561-564.
-
(2004)
Blood
, vol.104
, pp. 561-564
-
-
Cain, J.A.1
Grisolano, J.L.2
Laird, A.D.3
Tomasson, M.H.4
-
27
-
-
10744228170
-
Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/BxN model of rheumatoid arthritis
-
De Bandt, M., M. H. Ben Mahdi, V. Ollivier, M. Grossin, M. Dupuis, M. Gaudry, P. Bohlen, K. E. Lipson, A. Rice, Y. Wu, M. A. Gougerot-Pocidalo, and C. Pasquier. 2003. Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/BxN model of rheumatoid arthritis. J. Immunol. 171: 4853-4859.
-
(2003)
J. Immunol.
, vol.171
, pp. 4853-4859
-
-
De Bandt, M.1
Ben Mahdi, M.H.2
Ollivier, V.3
Grossin, M.4
Dupuis, M.5
Gaudry, M.6
Bohlen, P.7
Lipson, K.E.8
Rice, A.9
Wu, Y.10
Gougerot-Pocidalo, M.A.11
Pasquier, C.12
-
28
-
-
0029071688
-
Soluble mouse major histocompatibility complex class II molecules produced in Drosophila cells
-
Wallny, H. J., G. Sollami, and K. Karjalainen. 1995. Soluble mouse major histocompatibility complex class II molecules produced in Drosophila cells. Eur. J. Immunol. 25: 1262-1266.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 1262-1266
-
-
Wallny, H.J.1
Sollami, G.2
Karjalainen, K.3
-
29
-
-
0041932409
-
A selective and oral small molecule inhibitor of vascular epithelial growth factor receptor (VEGFR)-2 and VEGFR-1 inhibits neovascularization and vascular permeability
-
Patel, N., L. Sun, D. Moshinsky, H. Chen, K. M. Leahy, P. Le, K. G. Moss, X. Wang, A. Rice, D. Tarn, et al. 2003. A selective and oral small molecule inhibitor of vascular epithelial growth factor receptor (VEGFR)-2 and VEGFR-1 inhibits neovascularization and vascular permeability. J. Pharmacol. Exp. Ther. 306: 838-845.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, pp. 838-845
-
-
Patel, N.1
Sun, L.2
Moshinsky, D.3
Chen, H.4
Leahy, K.M.5
Le, P.6
Moss, K.G.7
Wang, X.8
Rice, A.9
Tarn, D.10
-
30
-
-
0036721329
-
Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
-
Kamath, A. T., S. Henri, F. Battye, D. F. Tough, and K. Shortman. 2002. Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs. Blood 100: 1734-1741.
-
(2002)
Blood
, vol.100
, pp. 1734-1741
-
-
Kamath, A.T.1
Henri, S.2
Battye, F.3
Tough, D.F.4
Shortman, K.5
-
31
-
-
0037131976
-
+ dendritic cells only after microbial stimulus
-
+ dendritic cells only after microbial stimulus. J. Exp. Med. 196: 1307-1319.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1307-1319
-
-
O'Keeffe, M.1
Hochrein, H.2
Vremec, D.3
Caminschi, I.4
Miller, J.L.5
Anders, E.M.6
Wu, L.7
Lahoud, M.H.8
Henri, S.9
Scott, B.10
-
32
-
-
0034670385
-
Development of CD8α-positive dendritic cells from a common myeloid progenitor
-
Traver, D., K. Akashi, M. Manz, M. Merad, T. Miyamoto, E. G. Engleman, and I. L. Weissman. 2000. Development of CD8α-positive dendritic cells from a common myeloid progenitor. Science 290: 2152-2154.
-
(2000)
Science
, vol.290
, pp. 2152-2154
-
-
Traver, D.1
Akashi, K.2
Manz, M.3
Merad, M.4
Miyamoto, T.5
Engleman, E.G.6
Weissman, I.L.7
-
33
-
-
0035383775
-
Dendritic cell potentials of early lymphoid and myeloid progenitors
-
Manz, M. G., D. Traver, T. Miyamoto, I. L. Weissman, and K. Akashi. 2001. Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood 97: 3333-3341.
-
(2001)
Blood
, vol.97
, pp. 3333-3341
-
-
Manz, M.G.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
Akashi, K.5
-
34
-
-
3142749595
-
Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin
-
Shigematsu, H., B. Reizis, H. Iwasaki, S. Mizuno, D. Hu, D. Traver, P. Leder, N. Sakaguchi, and K. Akashi. 2004. Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin. Immunity 21: 43-53.
-
(2004)
Immunity
, vol.21
, pp. 43-53
-
-
Shigematsu, H.1
Reizis, B.2
Iwasaki, H.3
Mizuno, S.4
Hu, D.5
Traver, D.6
Leder, P.7
Sakaguchi, N.8
Akashi, K.9
-
35
-
-
0029795529
-
Hematologic effects of flt3 ligand in vivo in mice
-
Brasel, K., H. J. McKenna, P. J. Morrissey, K. Charrier, A. E. Morris, C. C. Lee, D. E. Williams, and S. D. Lyman. 1996. Hematologic effects of flt3 ligand in vivo in mice. Blood 88: 2004-2012.
-
(1996)
Blood
, vol.88
, pp. 2004-2012
-
-
Brasel, K.1
McKenna, H.J.2
Morrissey, P.J.3
Charrier, K.4
Morris, A.E.5
Lee, C.C.6
Williams, D.E.7
Lyman, S.D.8
-
36
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo, M., I. L. Weissman, and K. Akashi. 1997. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91: 661-672.
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
37
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi, K., D. Traver, T. Miyamoto, and I. L. Weissman. 2000. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404: 193-197.
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
38
-
-
0029998037
-
FLT3 receptor expression on the surface of normal and malignant human hematopoietic cells
-
Turner, A. M., N. L. Lin, S. Issarachai, S. D. Lyman, and V. C. Broudy. 1996. FLT3 receptor expression on the surface of normal and malignant human hematopoietic cells. Blood 88: 3383-3390.
-
(1996)
Blood
, vol.88
, pp. 3383-3390
-
-
Turner, A.M.1
Lin, N.L.2
Issarachai, S.3
Lyman, S.D.4
Broudy, V.C.5
-
39
-
-
1642372843
-
Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors
-
Chen, W., S. Antonenko, J. M. Sederstrom, X. Liang, A. S. Chan, H. Kanzler, B. Blom, B. R. Blazar, and Y. J. Liu. 2004. Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors. Blood 103: 2547-2553.
-
(2004)
Blood
, vol.103
, pp. 2547-2553
-
-
Chen, W.1
Antonenko, S.2
Sederstrom, J.M.3
Liang, X.4
Chan, A.S.5
Kanzler, H.6
Blom, B.7
Blazar, B.R.8
Liu, Y.J.9
-
40
-
-
10644270729
-
Clonal type I interferon-producing and dendritic cell precursors are contained in both human lymphoid and myeloid progenitor populations
-
Chicha, L., D. Jarrossay, and M. G. Manz. 2004. Clonal type I interferon-producing and dendritic cell precursors are contained in both human lymphoid and myeloid progenitor populations. J. Exp. Med. 200: 1519-1524.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1519-1524
-
-
Chicha, L.1
Jarrossay, D.2
Manz, M.G.3
-
41
-
-
0036595322
-
Finding the next Gleevec: FLT3 targeted kinase inhibitor therapy for acute myeloid leukemia
-
Sawyers, C. L. 2002. Finding the next Gleevec: FLT3 targeted kinase inhibitor therapy for acute myeloid leukemia. Cancer Cell 1: 413-415.
-
(2002)
Cancer Cell
, vol.1
, pp. 413-415
-
-
Sawyers, C.L.1
-
42
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
O'Farrell, A. M., T. J. Abrams, H. A. Yuen, T. J. Ngai, S. G. Louie, K. W. Yee, L. M. Wong, W. Hong, L. B. Lee, A. Town, et al. 2003. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 101: 3597-3605.
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.6
Wong, L.M.7
Hong, W.8
Lee, L.B.9
Town, A.10
-
43
-
-
0037441745
-
The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3
-
Spiekermann, K., R. J. Dirschinger, R. Schwab, K. Bagrintseva, F. Faber, C. Buske, S. Schnittger, L. M. Kelly, D. G. Gilliland, and W. Hiddemann. 2003. The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3. Blood 101: 1494-1504.
-
(2003)
Blood
, vol.101
, pp. 1494-1504
-
-
Spiekermann, K.1
Dirschinger, R.J.2
Schwab, R.3
Bagrintseva, K.4
Faber, F.5
Buske, C.6
Schnittger, S.7
Kelly, L.M.8
Gilliland, D.G.9
Hiddemann, W.10
-
44
-
-
0035437140
-
A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations
-
Levis, M., K. F. Tse, B. D. Smith, E. Garrett, and D. Small. 2001. A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations. Blood 98: 885-887.
-
(2001)
Blood
, vol.98
, pp. 885-887
-
-
Levis, M.1
Tse, K.F.2
Smith, B.D.3
Garrett, E.4
Small, D.5
-
45
-
-
2442695516
-
Cotreatment with 17-allylamino-demethoxygeldanamycin and FLT-3 kinase inhibitor PKC412 is highly effective against human acute myelogenous leukemia cells with mutant FLT-3
-
George, P., P. Bali, P. Cohen, J. Tao, F. Guo, C. Sigua, A. Vishvanath, W. Fiskus, A. Scuto, S. Annavarapu, L. Moscinski, and K. Bhalla. 2004. Cotreatment with 17-allylamino-demethoxygeldanamycin and FLT-3 kinase inhibitor PKC412 is highly effective against human acute myelogenous leukemia cells with mutant FLT-3. Cancer Res. 64: 3645-3652.
-
(2004)
Cancer Res.
, vol.64
, pp. 3645-3652
-
-
George, P.1
Bali, P.2
Cohen, P.3
Tao, J.4
Guo, F.5
Sigua, C.6
Vishvanath, A.7
Fiskus, W.8
Scuto, A.9
Annavarapu, S.10
Moscinski, L.11
Bhalla, K.12
-
46
-
-
2342519992
-
Reconstitution of dendritic and natural killer-cell subsets after allogeneic stem cell transplantation: Effects of endogenous flt3 ligand
-
Chklovskaia, E., P. Nowbakht, C. Nissen, A. Gratwohl, M. Bargetzi, and A. Wodnar-Filipowicz. 2004. Reconstitution of dendritic and natural killer-cell subsets after allogeneic stem cell transplantation: effects of endogenous flt3 ligand. Blood 103: 3860-3868.
-
(2004)
Blood
, vol.103
, pp. 3860-3868
-
-
Chklovskaia, E.1
Nowbakht, P.2
Nissen, C.3
Gratwohl, A.4
Bargetzi, M.5
Wodnar-Filipowicz, A.6
-
47
-
-
0035761466
-
Development of thymic and splenic dendritic cell populations from different hemopoietic precursors
-
Wu, L., A. D'Amico, H. Hochrein, M. O'Keeffe, K. Shortman, and K. Lucas. 2001. Development of thymic and splenic dendritic cell populations from different hemopoietic precursors. Blood 98: 3376-3382.
-
(2001)
Blood
, vol.98
, pp. 3376-3382
-
-
Wu, L.1
D'Amico, A.2
Hochrein, H.3
O'Keeffe, M.4
Shortman, K.5
Lucas, K.6
-
48
-
-
0033987746
-
Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
-
Druker, B. J., and N. B. Lydon. 2000. Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia. J. Clin. Invest. 105: 3-7.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
-
49
-
-
0033816156
-
Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors
-
Buchdunger, E., C. L. Cioffi, N. Law, D. Stover, S. Ohno-Jones, B. J. Druker, and N. B. Lydon. 2000. Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors. J. Pharmacol. Exp. Ther. 295: 139-145.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 139-145
-
-
Buchdunger, E.1
Cioffi, C.L.2
Law, N.3
Stover, D.4
Ohno-Jones, S.5
Druker, B.J.6
Lydon, N.B.7
-
50
-
-
0034254249
-
Inhibition of c-kit receptor tyrosine kinase activity by STI571, a selective tyrosine kinase inhibitor
-
Heinrich, M. C., D. J. Griffith, B. J. Druker, C. L. Wait, K. A. Ott, and A. J. Zigler. 2000. Inhibition of c-kit receptor tyrosine kinase activity by STI571, a selective tyrosine kinase inhibitor. Blood 96: 925-932.
-
(2000)
Blood
, vol.96
, pp. 925-932
-
-
Heinrich, M.C.1
Griffith, D.J.2
Druker, B.J.3
Wait, C.L.4
Ott, K.A.5
Zigler, A.J.6
-
51
-
-
0035871874
-
ARG tyrosine kinase activity is inhibited by STI571
-
Okuda, K., E. Weisberg, D. G. Gilliland, and J. D. Griffin. 2001. ARG tyrosine kinase activity is inhibited by STI571. Blood 97: 2440-2448.
-
(2001)
Blood
, vol.97
, pp. 2440-2448
-
-
Okuda, K.1
Weisberg, E.2
Gilliland, D.G.3
Griffin, J.D.4
-
52
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker, B. J., M. Talpaz, D. J. Resta, B. Peng, E. Buchdunger, J. M. Ford, N. B. Lydon, H. Kantarjian, R. Capdeville, S. Ohno-Jones, and C. L. Sawyers. 2001. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. 344: 1031-1037.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
53
-
-
0037186915
-
Hematologic and cytogenetic responses to Imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian, H., C. Sawyers, A. Hochhaus, F. Guilhot, C. Schiffer, C. Gambacorti-Passerini, D. Niederwieser, D. Resta, R. Capdeville, U. Zoellner, et al. 2002. Hematologic and cytogenetic responses to Imatinib mesylate in chronic myelogenous leukemia. N. Engl. J. Med. 346: 645-652.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
Guilhot, F.4
Schiffer, C.5
Gambacorti-Passerini, C.6
Niederwieser, D.7
Resta, D.8
Capdeville, R.9
Zoellner, U.10
-
54
-
-
3042802079
-
+ peripheral blood progenitor cells
-
+ peripheral blood progenitor cells. Blood 103: 538-544.
-
(2004)
Blood
, vol.103
, pp. 538-544
-
-
Appel, S.1
Boehmler, A.M.2
Grunebach, F.3
Muller, M.R.4
Rupf, A.5
Weck, M.M.6
Hartmann, U.7
Reichardt, V.L.8
Kanz, L.9
Brummendorf, T.H.10
Brossart, P.11
-
55
-
-
1442331705
-
Imatinib mesylate impairs Flt3L-mediated dendritic cell expansion and antitumor effects in vivo
-
au
-
Taieb, J., K. Maruyama, C. Borg, M. Terme, and L. Zitvogel. 2004. Imatinib mesylate impairs Flt3L-mediated dendritic cell expansion and antitumor effects in vivo. Blood 103: 1966-7; au.
-
(2004)
Blood
, vol.103
, pp. 1966-1967
-
-
Taieb, J.1
Maruyama, K.2
Borg, C.3
Terme, M.4
Zitvogel, L.5
-
56
-
-
2942625414
-
Imatinib and plasmacytoid dendritic cell function in patients with chronic myeloid leukemia
-
Mohty, M., E. Jourdan, N. B. Mami, N. Vey, G. Damaj, D. Blaise, D. Isnardon, D. Olive, and B. Gaugler. 2004. Imatinib and plasmacytoid dendritic cell function in patients with chronic myeloid leukemia. Blood 103: 4666-4668.
-
(2004)
Blood
, vol.103
, pp. 4666-4668
-
-
Mohty, M.1
Jourdan, E.2
Mami, N.B.3
Vey, N.4
Damaj, G.5
Blaise, D.6
Isnardon, D.7
Olive, D.8
Gaugler, B.9
-
57
-
-
0033575383
-
Prevention of graft versus host disease by inactivation of host antigen-presenting cells
-
Shlomchik, W. D., M. S. Couzens, C. B. Tang, J. McNiff, M. E. Robert, J. Liu, M. J. Shlomchik, and S. G. Emerson. 1999. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 285: 412-415.
-
(1999)
Science
, vol.285
, pp. 412-415
-
-
Shlomchik, W.D.1
Couzens, M.S.2
Tang, C.B.3
McNiff, J.4
Robert, M.E.5
Liu, J.6
Shlomchik, M.J.7
Emerson, S.G.8
-
58
-
-
0037114157
-
+ T cells to elicit hepatic graft-versus-host disease
-
+ T cells to elicit hepatic graft-versus-host disease. J. Immunol. 169: 7111-7118.
-
(2002)
J. Immunol.
, vol.169
, pp. 7111-7118
-
-
Zhang, Y.1
Shlomchik, W.D.2
Joe, G.3
Louboutin, J.P.4
Zhu, J.5
Rivera, A.6
Giannola, D.7
Emerson, S.G.8
-
60
-
-
2942627451
-
Host dendritic cells alone are sufficient to initiate acute graft-versus-host disease
-
Duffner, U. A., Y. Maeda, K. R. Cooke, P. Reddy, R. Ordemann, C. Liu, J. L. Ferrara, and T. Teshima. 2004. Host dendritic cells alone are sufficient to initiate acute graft-versus-host disease. J. Immunol. 172: 7393-7398.
-
(2004)
J. Immunol.
, vol.172
, pp. 7393-7398
-
-
Duffner, U.A.1
Maeda, Y.2
Cooke, K.R.3
Reddy, P.4
Ordemann, R.5
Liu, C.6
Ferrara, J.L.7
Teshima, T.8
-
61
-
-
2442658900
-
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease
-
Merad, M., P. Hoffmann, E. Ranheim, S. Slaymaker, M. G. Manz, S. A. Lira, I. Charo, D. N. Cook, I. L. Weissman, S. Strober, and E. G. Engleman. 2004. Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat. Med. 10: 510-517.
-
(2004)
Nat. Med.
, vol.10
, pp. 510-517
-
-
Merad, M.1
Hoffmann, P.2
Ranheim, E.3
Slaymaker, S.4
Manz, M.G.5
Lira, S.A.6
Charo, I.7
Cook, D.N.8
Weissman, I.L.9
Strober, S.10
Engleman, E.G.11
|