Nucleotide modification at the γ-phosphate leads to the improved fidelity of HIV-1 reverse transcriptase

Nucleic Acids Research

Volumn 33, Issue 15, 2005, Pages 4865-4873

  Mulder, Brent A ^a,c   Anaya, Steve ^a   Yu, Peilin ^a   Lee, Keun Woo ^a   Nguyen, Anvy ^a,c   Murphy, Jason ^b   Willson, Richard ^a,b,c   Briggs, James M ^a,c   Gao, Xiaolian ^a   Hardin, Susan H ^a,c  

^a University of Houston   (United States)

^b University of Houston   (United States)

^c VisiGen Biotechnologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; NAPHTHALENE DERIVATIVE; NUCLEOTIDE; PHOSPHATE; RNA DIRECTED DNA POLYMERASE; SULFONIC ACID DERIVATIVE; 1-NAPHTHYLAMINE-5-SULFONIC ACID; 5 AMINO 1 NAPHTHALENESULFONIC ACID; DEOXYRIBONUCLEOTIDE; NAPHTHALENESULFONIC ACID DERIVATIVE;

ANALYTICAL ERROR; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME SPECIFICITY; FREQUENCY ANALYSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MUTATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

BINDING SITES; DEOXYRIBONUCLEOTIDES; HIV-1 REVERSE TRANSCRIPTASE; MODELS, MOLECULAR; MUTATION; NAPHTHALENESULFONATES; PHOSPHATES;

EID: 24744446263     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gki779     Document Type: Article

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