Unmet medical needs and therapeutic opportunities in stable angina

European Heart Journal, Supplement

Volumn 7, Issue H, 2005, Pages

  Steg, Philippe Gabriel ^a   Himbert, Dominique ^a  

^a BICHAT HOSPITAL   (France)

Author keywords

Angina; Evidence based medicine; Revascularization

Indexed keywords

ACETYLSALICYLIC ACID; ANTIANGINA PECTORIS AGENT; ANTITHROMBOCYTIC AGENT; ATORVASTATIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CLOPIDOGREL; DIHYDROPYRIDINE DERIVATIVE; DILTIAZEM; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IVABRADINE; METOPROLOL; MOLSIDOMINE; NICORANDIL; NIFEDIPINE; NITRIC ACID DERIVATIVE; PERINDOPRIL; POTASSIUM CHANNEL BLOCKING AGENT; PROPRANOLOL DERIVATIVE; PYRIDINE DERIVATIVE; RAMIPRIL; RANOLAZINE; SIMVASTATIN; TRANDOLAPRIL; TRIMETAZIDINE;

ARTICLE; BRADYCARDIA; CLINICAL TRIAL; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DISEASE; HEADACHE; HEART FAILURE; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HEMODYNAMICS; HUMAN; HYPOTENSION; INOTROPISM; LEG EDEMA; META ANALYSIS; PATIENT COMPLIANCE; PRESCRIPTION; PRIORITY JOURNAL; QUALITY OF LIFE; STABLE ANGINA PECTORIS; SYMPTOMATOLOGY; TRAINING; TRANSLUMINAL CORONARY ANGIOPLASTY;

EID: 24744431675     PISSN: 1520765X     EISSN: None     Source Type: Journal    
DOI: 10.1093/eurheartj/sui049     Document Type: Article

References (48)

1. Management of stable angina pectoris. Recommendations of the Task Force of the European Society of Cardiology. Eur Heart J 1997;18:394-413.
2. Royal College of General Practitioners, the Office of Population Censuses and Surveys, and the Department of Health. Morbidity Statistics from General Practice, Fourth National Study, 1991-1992. London: Her Majesty's Stationery Office; 1995.
3. Pocock S, Henderson R, Seed P et al. Quality of life, employment status, and anginal symptoms after coronary angioplasty or bypass surgery. 3-year follow-up in the Randomized Intervention Treatment of Angina (RITA) Trial. Circulation 1996;94:135-142.
4. Henderson RA, Pocock SJ, Clayton TC et al. Second Randomized Intervention Treatment of Angina (RITA-2) Trial Participants. Seven-year outcome in the RITA-2 trial: coronary angioplasty versus medical therapy. J Am Coll Cardiol 2003;42:1161-1170.
5. The TIME investigators. Trial of Invasive versus Medical therapy in Elderly patients with chronic symptomatic coronary-artery disease (TIME): a randomised trial. Lancet 2001;358:951-957.
6. Pfisterer M, Buser P, Osswald S et al. Trial of Invasive versus Medical Therapy in Elderly patients (TIME) Investigators. Outcome of elderly patients with chronic symptomatic coronary artery disease with an invasive vs optimized medical treatment strategy: one-year results of the randomized TIME trial. JAMA 2003;289:1117-1123.
7. Pfisterer M. Trial of Invasive versus Medical therapy in Elderly patients Investigators. Long-term outcome in elderly patients with chronic angina managed invasively versus by optimized medical therapy: four-year follow-up of the randomized Trial of Invasive versus Medical therapy in Elderly patients (TIME). Circulation 2004;110:1213-1218.
8. Mannheimer C, Camici P, Chester MR et al. The problem of chronic refractory angina; report from the ESC Joint Study Group on the Treatment of Refractory Angina. Eur Heart J 2002;23:355-370.
9. Zellweger MJ, Weinbacher M, Zutter AW et al. Long-term outcome of patients with silent versus symptomatic ischemia six months after percutaneous coronary intervention and stenting. J Am Coll Cardiol 2003;42:33-40.
10. Holubkov R, Laskey WK, Haviland A et al. Angina 1 year after percutaneous coronary intervention: a report from the NHLBI Dynamic Registry. Am Heart J 2002;144:826-833.
11. Steg PG, Dabbous OH, Feldman LJ et al. Determinants and prognostic impact of heart failure complicating acute coronary syndromes: observations from the Global Registry of Acute Coronary Events (GRACE). Circulation 2004;109:494-499.
12. Hjemdahl P, Eriksson SV, Held C et al. Prognosis of patients with stable angina pectoris on antianginal drug therapy. Am J Cardiol 1996;77:6D-15D.
13. Mukherjee D, Fang J, Chetcuti S et al. Impact of combination evidence-based medical therapy on mortality in patients with acute coronary syndromes. Circulation 2004;109:745-749.
14. Mehta RH, Montoye CK, Gallogly M et al. Improving quality of care for acute myocardial infarction. The Guidelines Applied in Practice (GAP) Initiative. JAMA 2002;287:1269-1276.
15. Daly CA, Clemens D, Lopez-Sendon JL et al. on behalf of the Euro Heart Survey investigators. The initial management of stable angina in Europe, from the Euro Heart Survey: a description of pharmacological management and revascularization strategies initiated within the first month of presentation to a cardiologist in the Euro Heart Survey of Stable Angina. Eur Heart J 2005;26:1011-1022.
16. Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002;324:71-86.
17. Gibbons RJ, Abrams J, Chatterjee K et al.; American College of Cardiology; American Heart Association Task Force on Practice Guidelines.Committee on the Management of Patients With Chronic Stable Angina. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina-summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina). Circulation 2002;107:149-158.
18. Yusuf S, Peto R, Lewis J et al. Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis 1985;27:335-371.
19. Silberman S, Neukirch-Stoop C, Steg PG. A rapid desensitization procedure for patients with aspirin hypersensitivity undergoing coronary stenting. Am J Cardiol 2005;95:509-510.
20. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet 1996;348:1329-1339.
21. Bhatt DL, Topol EJ; Clopidogrel for High Atherothrombotic Risk Ischemic Stabilization, Management, and Avoidance Executive Committee. Clopidogrel added to aspirin versus aspirin alone in secondary prevention and high-risk primary prevention: rationale and design of the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial. Am Heart J 2004;148:263-268.
22. LaRosa JC, Grundy SM, Waters DD et al.; Treating to New Targets (TNT) investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 2005;352:1425-1435.
23. Grundy SM, Cleeman JI, Merz CN et al.; National Heart, Lung, and Blood Institute American College of Cardiology Foundation American Heart Association. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 2004;110:227-239.
24. Yusuf S, Sleight P, Pogue J et al. Effects of an angiotensin-converting- enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000;342:145-153.
25. Fox KM. Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003;362:782-788.
26. Braunwald E, Domanski MJ, Fowler SE et al.; PEACE Trial Investigators. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004;351:2058-2068.
27. Yusuf S, Pogue J. ACE inhibition in stable coronary artery disease. N Engl J Med 2005;352:937-939.
28. Psaty BM, Heckbert SR, Koepsell TD et al. The risk of myocardial infarction associated with antihypertensive drug therapies. JAMA 1995;274:620-625.
29. Poole-Wilson PA, Lubsen J, Kirwan BA et al. Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial. Lancet 2004;364:849-857.
30. IONA Study Group. Effect of nicorandil on coronary events in patients with stable angina: the Impact Of Nicorandil in Angina (IONA) randomised trial. Lancet 2002;359:1269-1275.
31. Sellier P, Harpey C, Corona P et al. Acute effects of trimetazidine on ergometric parameters in effort angina. Cardiovasc Drugs Ther 1990;4(Suppl. 4):820-821.
32. Sellier P. Chronic effects of trimetazidine on ergometric parameters in effort angina. Cardiovasc Drugs Ther 1990;4(Suppl. 4):822-823.
33. Passeron J. Effectiveness of trimetazidine in stable effort angina due to chronic coronary insufficiency. A double-blind versus placebo study [in French]. Presse Med 1986;15:1775-1778.
34. Gallet M. Clinical effectiveness of trimetazidine in stable effort angina. A double-blind versus placebo controlled study [in French]. Presse Med 1986;15:1779-1782.
35. Detry JM, Leclercq PJ. Trimetazidine European Multicenter Study versus propranolol in stable angina pectoris: contribution of Holter electrocardiographic ambulatory monitoring. Am J Cardiol 1995;76:8B-11B.
36. Dalla-Volta S, Maraglino G, Della-Valentina P et al. Comparison of trimetazidine with nifedipine in effort angina: a double-blind, crossover study. Cardiovasc Drugs Ther 1990;4(Suppl. 4):853-859.
37. Manchanda SC, Krishnaswami S. Combination treatment with trimetazidine and diltiazem in stable angina pectoris. Heart 1997;78:353-357.
38. Szwed H, Sadowski Z, Elikowski W et al. Combination treatment in stable effort angina using trimetazidine and metoprolol: results of a randomized, double-blind, multicentre study (TRIMPOL II). TRI-Metazidine in POLand. Eur Heart J 2001;22:2267-2274.
39. Chaitman BR, Skettino SL, Parker JO et al. Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina. J Am Coll Cardiol 2004;43:1375-1382.
40. Chaitman BR, Pepine CJ, Parker JO et al. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. JAMA 2004;291:309-316.
41. Hambrecht R, Wolf A, Gielen S et al. Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med 2000;342:454-460.
42. Adams V, Lenk K, Linke A. et al. Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Arterioscler Thromb Vasc Biol 2004;24:684-690.
43. Hambrecht R, Walther C, Mobius-Winkler S et al. Percutaneous coronary angioplasty compared with exercise training in patients with stable coronary artery disease: a randomized trial. Circulation 2004;109:1371-1378.
44. Morrow DA, Gersh BJ, Braunwald E. Chronic coronary artery disease. In: Braunwald's Heart disease. A Textbook of Cardiovascular Medicine.7th ed. Philadelphia: Saunders; 2004. p1281-1354.
45. De Backer G, Ambrosioni E, Borch-Johnsen K et al. European Society of Cardiology Committee for Practice Guidelines. European guidelines on cardiovascular disease prevention in clinical practice: third joint task force of European and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of eight societies and by invited experts). Eur J Cardiovasc Prev Rehabil 2003;10:S1-S10.
46. Bartnik M, Ryden L, Ferrari R et al. on behalf of the Euro Heart Survey investigators. The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe. The Euro Heart Survey on diabetes and the heart. Eur Heart J 2004;25:1880-1890.
47. Granger CB, Steg PG, Peterson E et al. for the GRACE Investigators. Performance measures of use of evidence-based medicine and mortality in an international, prospective, observational study. Am J Med, in press.
48. Eagle KA, Kline-Rogers E, Goodman SG et al. Adherence to evidence-based therapies after discharge for acute coronary syndromes: an ongoing, prospective, observational study. Am J Med 2004;117:73-81.