Variation in IL-1β gene expression is a major determinant of genetic differences in arthritis aggressivity in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 35, 2005, Pages 12489-12494

  Ohmura, Koichiro ^a   Johnsen, Alyssa ^a   Ortiz Lopez, Adriana ^a   Desany, Paul ^a   Roy, Matt ^a   Besse, Whitney ^a   Rogus, John ^a,b,c   Bogue, Molly ^d   Puech, Anne ^e   Lathrop, Mark ^e   Mathis, Diane ^a   Benoist, Christophe ^a  

^a JOSLIN DIABETES CENTER   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d JACKSON LABORATORY   (United States)

^e CENTRE NATIONAL DE GÉNOTYPAGE   (France)

Author keywords

Autoimmunity; Genetics; Inflammation; Mouse Phenome Project

Indexed keywords

IMMUNOGLOBULIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; INTERLEUKIN 1;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; AUTOIMMUNITY; BREEDING; CHR2 GENE; DISEASE PREDISPOSITION; DISEASE SEVERITY; FEMALE; GENE; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOME ANALYSIS; HAPLOTYPE; INFLAMMATION; MALE; MOUSE; MOUSE STRAIN; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPLEEN CELL; ANIMAL; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; BIOSYNTHESIS; CHROMOSOME MAP; COMPARATIVE STUDY; COMPUTER SIMULATION; GENETICS; HUMAN; IMMUNOLOGY; NONOBESE DIABETIC MOUSE; SPECIES DIFFERENCE;

ANIMALIA;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CHROMOSOME MAPPING; COMPUTER SIMULATION; GENE EXPRESSION; HUMANS; INTERLEUKIN-1; MICE; MICE, INBRED BALB C; MICE, INBRED NOD; MODELS, GENETIC; RNA, MESSENGER; SPECIES SPECIFICITY;

EID: 24644504780     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0504325102     Document Type: Article

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