-
1
-
-
0030898417
-
Mitogen-activated protein kinase pathways
-
Robinson MJ, Cobb MH. Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 1997: 9:180-6.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 180-186
-
-
Robinson, M.J.1
Cobb, M.H.2
-
2
-
-
0032935664
-
Mitogen-activated protein kinases: Specific messages from ubiquitous messengers
-
Schaeffer HJ, Weber MJ. Mitogen-activated protein kinases: Specific messages from ubiquitous messengers. Mol Cell Biol 1999; 19:2435-44.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2435-2444
-
-
Schaeffer, H.J.1
Weber, M.J.2
-
3
-
-
0042172963
-
Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice
-
Lozano J, Xing R, Cai Z, Jensen HJ, Trempus C, Mark W, Cannon R, Kolesnick R. Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice. Cancer Res 2003; 63:4232-8.
-
(2003)
Cancer Res
, vol.63
, pp. 4232-4238
-
-
Lozano, J.1
Xing, R.2
Cai, Z.3
Jensen, H.J.4
Trempus, C.5
Mark, W.6
Cannon, R.7
Kolesnick, R.8
-
4
-
-
0035105516
-
p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression
-
Westermarck J, Li SP, Kallunki T, Han J, Kahari VM. p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression. Mol Cell Biol 2001; 21:2373-83.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2373-2383
-
-
Westermarck, J.1
Li, S.P.2
Kallunki, T.3
Han, J.4
Kahari, V.M.5
-
5
-
-
0038476605
-
Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells
-
Shelton JG, Steelman LS, Lee JT, Knapp SL, Blalock WL, Moye PW, Franklin RA, Pohnert SC, Mirza AM, McMahon M, McCubrey JA. Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells. Oncogene 2003; 22:2478-92.
-
(2003)
Oncogene
, vol.22
, pp. 2478-2492
-
-
Shelton, J.G.1
Steelman, L.S.2
Lee, J.T.3
Knapp, S.L.4
Blalock, W.L.5
Moye, P.W.6
Franklin, R.A.7
Pohnert, S.C.8
Mirza, A.M.9
McMahon, M.10
McCubrey, J.A.11
-
6
-
-
0035890044
-
Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis
-
Subramanian RR, Masters SC, Zhang H, Fu H. Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis. Exp Cell Res 2001; 271:142-51.
-
(2001)
Exp Cell Res
, vol.271
, pp. 142-151
-
-
Subramanian, R.R.1
Masters, S.C.2
Zhang, H.3
Fu, H.4
-
7
-
-
0038724937
-
Role of Raf in vascular protection from distinct apoptotic stimuli
-
Alavi A, Hood JD, Frausto R, Stupack DG, Cheresh DA. Role of Raf in vascular protection from distinct apoptotic stimuli. Science 2003; 301:94-6.
-
(2003)
Science
, vol.301
, pp. 94-96
-
-
Alavi, A.1
Hood, J.D.2
Frausto, R.3
Stupack, D.G.4
Cheresh, D.A.5
-
8
-
-
0038476592
-
Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation
-
Kovalenko D, Yang X, Nadeau RJ, Harkins LK, Friesel R. Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation. J Biol Chem 2003; 278(16):14087-91.
-
(2003)
J Biol Chem
, vol.278
, Issue.16
, pp. 14087-14091
-
-
Kovalenko, D.1
Yang, X.2
Nadeau, R.J.3
Harkins, L.K.4
Friesel, R.5
-
9
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
-
Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS, Sukhatme VP. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 1995; 375:577-81.
-
(1995)
Nature
, vol.375
, pp. 577-581
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.M.3
Foster, D.4
Brugge, J.S.5
Sukhatme, V.P.6
-
10
-
-
0032100732
-
HIF-1 alpha is required for solid tumor formation and embryonic vascularization
-
Ryan HE, Lo J, Johnson RS. HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J 1998; 17:3005-15.
-
(1998)
EMBO J
, vol.17
, pp. 3005-3015
-
-
Ryan, H.E.1
Lo, J.2
Johnson, R.S.3
-
11
-
-
0032963472
-
Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression
-
Nor JE, Christensen J, Mooney DJ, Polverini PJ. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J Pathol 1999; 154:375-84.
-
(1999)
Am J Pathol
, vol.154
, pp. 375-384
-
-
Nor, J.E.1
Christensen, J.2
Mooney, D.J.3
Polverini, P.J.4
-
12
-
-
0034699326
-
Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis
-
Baek JH, Jang JE, Kang CM, Chung HY, Kim ND, K.W. Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis. Oncogene 2000; 19:4621-31.
-
(2000)
Oncogene
, vol.19
, pp. 4621-4631
-
-
Baek, J.H.1
Jang, J.E.2
Kang, C.M.3
Chung, H.Y.4
Kim, N.D.5
K, W.6
-
13
-
-
0028834638
-
Both v-Ha-ras and v-raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells
-
Grugel S, Finkenzeller G, Weindel K, Barleon B, Marme D. Both v-Ha-ras and v-raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells. J Biol Chem 1995; 43:25915-9.
-
(1995)
J Biol Chem
, vol.43
, pp. 25915-25919
-
-
Grugel, S.1
Finkenzeller, G.2
Weindel, K.3
Barleon, B.4
Marme, D.5
-
14
-
-
0028822834
-
Mutant ras oncogenes upregulate VEGF/VPF expression; implications for induction and inhibition of tumor angiogenesis
-
Rak J, Mitsuhashi Y, Bayko L, Filmus J, Shirasawa S, Sasazuki T, Kerbel RS. Mutant ras oncogenes upregulate VEGF/VPF expression; implications for induction and inhibition of tumor angiogenesis. Cancer Res 1995; 55:4575-80.
-
(1995)
Cancer Res
, vol.55
, pp. 4575-4580
-
-
Rak, J.1
Mitsuhashi, Y.2
Bayko, L.3
Filmus, J.4
Shirasawa, S.5
Sasazuki, T.6
Kerbel, R.S.7
-
15
-
-
0035860246
-
MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF
-
Sodhi A, Montaner S, Miyazaki H, Gutkind JS. MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF. Biochem Biophys Res Commun 2001; 287:292-300.
-
(2001)
Biochem Biophys Res Commun
, vol.287
, pp. 292-300
-
-
Sodhi, A.1
Montaner, S.2
Miyazaki, H.3
Gutkind, J.S.4
-
16
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nat Rev Genet 2002; 3:737-47.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
Sharp, P.A.2
-
17
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 2002; 26:199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
18
-
-
0037062951
-
RNA interference
-
Hannon GJ. RNA interference. Nature 2002; 418:244-51.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
19
-
-
0037213559
-
Mammalian RNAi for the masses
-
Shi Y. Mammalian RNAi for the masses. Trends Genet 2003; 19:9-12.
-
(2003)
Trends Genet
, vol.19
, pp. 9-12
-
-
Shi, Y.1
-
20
-
-
0036066508
-
SiRNA-directed inhibition of HIV-1 infection
-
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman RG, Lieberman J, Shankar P, Sharp PA. SiRNA-directed inhibition of HIV-1 infection. Nat Med 2002; 8:681-6.
-
(2002)
Nat Med
, vol.8
, pp. 681-686
-
-
Novina, C.D.1
Murray, M.F.2
Dykxhoorn, D.M.3
Beresford, P.J.4
Riess, J.5
Lee, S.K.6
Collman, R.G.7
Lieberman, J.8
Shankar, P.9
Sharp, P.A.10
-
21
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2002; 2:243-7.
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
22
-
-
0037197914
-
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
-
USA
-
Yu JY, DeRuiter SL, Turner DL. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002; 99:6047-52.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 6047-6052
-
-
Yu, J.Y.1
DeRuiter, S.L.2
Turner, D.L.3
-
23
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
USA
-
Sui G, Soohoo C, Affarel B, Gay F, Shi Y, Forrester WC. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002; 99:5515-20.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
Soohoo, C.2
Affarel, B.3
Gay, F.4
Shi, Y.5
Forrester, W.C.6
-
24
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002; 296:550-3.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
25
-
-
0037197914
-
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
-
USA
-
Yu JY, DeRuiter SL, Turner DL. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002; 99:6047-52.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 6047-6052
-
-
Yu, J.Y.1
DeRuiter, S.L.2
Turner, D.L.3
-
26
-
-
0034667370
-
RhoC GTPase. A novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype
-
Van Golen KL, Wu ZF, Qiao XT, Bao LW, Merajver SD. RhoC GTPase. A novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype. Cancer Res 2000; 60:5832-8
-
(2000)
Cancer Res
, vol.60
, pp. 5832-5838
-
-
Van Golen, K.L.1
Wu, Z.F.2
Qiao, X.T.3
Bao, L.W.4
Merajver, S.D.5
-
27
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nat Rev Genet 2002; 3:737-47
-
(2002)
Nat Rev Genet
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
Sharp, P.A.2
-
28
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411:494-8.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
29
-
-
0036245743
-
Expanding small RNA interference
-
Tuschl T. Expanding small RNA interference. Nat Biotechnol 2002; 20:446-8.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 446-448
-
-
Tuschl, T.1
-
30
-
-
0032498640
-
Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
-
Eliceiri BP, Klemke R, Stromblad S, Cheresh DA. Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J Cell Biol 1998; 140:1255.
-
(1998)
J Cell Biol
, vol.140
, pp. 1255
-
-
Eliceiri, B.P.1
Klemke, R.2
Stromblad, S.3
Cheresh, D.A.4
-
31
-
-
0025277489
-
Mutational activation of c-raf-1 and definition of the minimal transforming sequence
-
Heidecker G, Huleihel M, Cleveland JL, et al. Mutational activation of c-raf-1 and definition of the minimal transforming sequence. Mol Cell Biol 1990; 10:2503.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 2503
-
-
Heidecker, G.1
Huleihel, M.2
Cleveland, J.L.3
-
32
-
-
0024384470
-
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
-
Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 1989; 161:851-8.
-
(1989)
Biochem Biophys Res Commun
, vol.161
, pp. 851-858
-
-
Ferrara, N.1
Henzel, W.J.2
-
33
-
-
0025933145
-
The vascular endothelial growth factor family of polypeptides
-
Ferrara N, Houck KA, Jakeman LB, Winer J, Leung WJD. The vascular endothelial growth factor family of polypeptides. Cell Biochem 1991; 47:211-8.
-
(1991)
Cell Biochem
, vol.47
, pp. 211-218
-
-
Ferrara, N.1
Houck, K.A.2
Jakeman, L.B.3
Winer, J.4
Leung, W.J.D.5
-
34
-
-
0025935279
-
Vascular permeability factor: A unique regulator of blood vessel function
-
Connolly DT. Vascular permeability factor: A unique regulator of blood vessel function. J Cell Biochem 1991; 47:219-23.
-
(1991)
J Cell Biochem
, vol.47
, pp. 219-223
-
-
Connolly, D.T.1
-
35
-
-
0032568150
-
Stabilization of wild-type p53 by hypoxia-inducible factor 1a
-
An WG, Kanekal M, Simon MC, Maltepe E, Blagosklonny MV, Neckers LM. Stabilization of wild-type p53 by hypoxia-inducible factor 1a. Nature 1998; 392:405-8.
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.V.5
Neckers, L.M.6
-
36
-
-
0029051439
-
Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
USA
-
Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92:5510-4.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
37
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 2002; 26:199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
38
-
-
0036066508
-
siRNA-directed inhibition of HIV-1 infection
-
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman RG, Lieberman J, Shankar P, Sharp PA. siRNA-directed inhibition of HIV-1 infection. Nat Med 2002; 8:681-6.
-
(2002)
Nat Med
, vol.8
, pp. 681-686
-
-
Novina, C.D.1
Murray, M.F.2
Dykxhoorn, D.M.3
Beresford, P.J.4
Riess, J.5
Lee, S.K.6
Collman, R.G.7
Lieberman, J.8
Shankar, P.9
Sharp, P.A.10
-
39
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2002; 2:243-7.
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
40
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
USA
-
Sui G, Soohoo C, Affarel B, Gay F, Shi Y, Forrester WC. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002; 99:5515-20.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
Soohoo, C.2
Affarel, B.3
Gay, F.4
Shi, Y.5
Forrester, W.C.6
|