2,4,5-Triphenylisothiazol-3(2H)-one 1,1-dioxides as inhibitors of human leukocyte elastase

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 20, Issue 4, 2005, Pages 341-347

  Gütschow, Michael ^a   Pietsch, Markus ^a   Themann, Andrea ^a   Fahrig, Janine ^b   Schulze, Bärbel ^b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

1,1 dioxides; 2,4,5 triphenylisothiazol 3(2H) one; Human leukocyte elastase; Inhibition; Sultams

Indexed keywords

2 (2 CHLORO 4 NITROPHENYL) 4,5 DIPHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 2 (2 CHLORO 4 NITROPHENYL) 5 (4 METHOXYPHENYL) 4 PHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 2 (2 TRIFLUOROMETHYL 4 NITROPHENYL) 4,5 DIPHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 2 (2,5 DICHLORO 4 ISOPROPYLOXYPHENYL) 5 (4 METHOXYPHENYL) 4 PHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 2 (3 NITROPHENYL) 4,5 DIPHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 2 (4 TRIFLUOROMETHYLPHENYL) 4,5 DIPHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 2 (4 TRIFLUOROMETHYLPHENYL) 5 (4 METHOXYPHENYL) 4 PHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 2,4,5 TRIPHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE DERIVATIVE; 5 (4 METHOXYPHENYL) 2 (2,4 DINITROPHENYL) 4 PHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 5 (4 METHOXYPHENYL) 2 (3 NITROPHENYL) 4 PHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; 5 (4 METHOXYPHENYL) 2 (4 NITROPHENYL) 4 PHENYLISOTHIAZOL 3(2H) ONE 1,1 DIOXIDE; ELASTASE INHIBITOR; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TIME;

ENZYME INHIBITORS; HUMANS; KINETICS; LEUKOCYTE ELASTASE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THIAZOLES;

KOBUS;

EID: 24644471969     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360500148783     Document Type: Article

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