Therapeutic promises of leukocyte elastase and macrophage metalloelastase inhibitors for the treatment of pulmonary emphysema

Expert Opinion on Therapeutic Patents

Volumn 9, Issue 7, 1999, Pages 869-895

  Skiles, J W ^a   Jeng, A Y ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

1 proteinase inhibitor; Emphysema; Inflammation; Leukocyte elastase; Macrophage metalloelastase; Matrix metalloproteinase (MMP); MMP 12; Tissue inhibitors of metalloproteinases

Indexed keywords

ASPARTIC ACID; CGS 27023A; ELASTIN; HISTIDINE; KETONE; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; MATRIX METALLOPROTEINASE; PANCREATIC ELASTASE; PROTEINASE INHIBITOR; SERINE; SERINE PROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE; UNINDEXED DRUG;

ACYLATION; CHRONIC INFLAMMATION; DRUG DESIGN; DRUG SYNTHESIS; EMPHYSEMA; ENZYME ACTIVE SITE; HUMAN; NONHUMAN; PATENT; PATHOGENESIS; REVIEW;

EID: 0032767857     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.9.7.869     Document Type: Review

References (69)