The promiscuous primase

Trends in Genetics

Volumn 21, Issue 10, 2005, Pages 568-572

  Lao Sirieix, Si Houy ^a   Pellegrini, Luca ^a   Bell, Stephen D ^a  

^a HUTCHISON MRC RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE; DNA POLYMERASE; DNA PRIMASE; LIGASE;

AMINO TERMINAL SEQUENCE; BACILLUS CEREUS; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; DNA REPAIR; DNA REPLICATION; DNA STRAND; DNA STRAND BREAKAGE; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME STRUCTURE; EUKARYOTE; MOLECULAR MECHANICS; NONHUMAN; OPEN READING FRAME; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN MOTIF; PYROCOCCUS; REVIEW; RNA SYNTHESIS; SULFOLOBUS;

CATALYTIC DOMAIN; DNA PRIMASE; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; EVOLUTION, MOLECULAR; INTERSPERSED REPETITIVE SEQUENCES; MODELS, MOLECULAR;

ARCHAEA; EUKARYOTA;

EID: 24644454684     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2005.07.010     Document Type: Review

References (31)

1. D.N. Frick, and C.C. Richardson DNA primases Annu. Rev. Biochem. 70 2001 39 80
2. L.D. Liu The archaeal DNA primase - biochemical characterization of the p41-p46 complex from Pyrococcus furiosus J. Biol. Chem. 276 2001 45484 45490
3. A.A. Bocquier Archaeal primase: bridging the gap between RNA and DNA polymerases Curr. Biol. 11 2001 452 456
4. S.H. Lao-Sirieix, and S.D. Bell The heterodimeric primase of the hyperthermophilic archaeon Sulfolobus solfataricus possesses DNA and RNA primase, polymerase and 3′-terminal nucleotidyl transferase activities J. Mol. Biol. 344 2004 1251 1263
5. F. Matsunaga Identification of short 'eukaryotic' Okazaki fragments synthesized from a prokaryotic replication origin EMBO Rep. 4 2003 154 158
6. M. De Falco The DNA primase of Sulfolobus solfataricus is activated by substrates containing a thymine-rich bubble and has a 3′-terminal nucleotidyl-transferase activity Nucleic Acids Res. 32 2004 5223 5230
7. M.A. Augustin Crystal structure of a DNA-dependent RNA polymerase (DNA primase) Nat. Struct. Biol. 8 2001 57 61
8. N. Ito Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis Genes Cells 8 2003 913 923
9. H. Pan, and D.B. Wigley Structure of the zinc-binding domain of Bacillus stearothermophilus DNA primase Structure 8 2000 231 239
10. T.A. Steitz A unified polymerase mechanism for nonhomologous DNA and RNA polymerases Science 266 1994 2022 2025
11. M.R. Sawaya Crystal-structure of rat DNA-polymerase-beta - evidence for a common polymerase mechanism Science 264 1994 1930 1935
12. G. Lipps A novel type of replicative enzyme harbouring ATPase, primase and DNA polymerase activity EMBO J. 22 2003 2516 2525
13. G. Lipps Structure of a bifunctional DNA primase-polymerase Nat. Struct. Mol. Biol. 11 2004 157 162
14. A.T. McGeoch, and S.D. Bell Eukaryotic/archaeal primase and MCM proteins encoded in a bacteriophage genome Cell 120 2005 167 168
15. B.W. Kirk, and R.D. Kuchta Arg304 of human DNA primase is a key contributor to catalysis and NTP binding: primase and the family X polymerases share significant sequence homology Biochemistry 38 1999 7727 7736
16. U. Hubscher Eukaryotic DNA polymerases Annu. Rev. Biochem. 71 2002 133 163
17. K. Ramadan De novo DNA synthesis by human DNA polymerase lambda, DNA polymerase mu and terminal deoxyribonucleotidyl transferase J. Mol. Biol. 339 2004 395 404
18. K.N. Mahajan Association of terminal deoxynucleotidyl transferase with Ku Proc. Natl. Acad. Sci. U. S. A. 96 1999 13926 13931
19. M. Garcia-Diaz DNA polymerase lambda, a novel DNA repair enzyme in human cells J. Biol. Chem. 277 2002 13184 13191
20. M. Garcia-Diaz DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis J. Mol. Biol. 301 2000 851 867
21. O. Dominguez DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells EMBO J. 19 2000 1731 1742
22. J.F. Ruiz Lack of sugar discrimination by human Pol mu requires a single glycine residue Nucleic Acids Res. 31 2003 4441 4449
23. K. Ramadan Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions J. Mol. Biol. 328 2003 63 72
24. K. Bebenek The frameshift infidelity of human DNA polymerase lambda. Implications for function J. Biol. Chem. 278 2003 34685 34690
25. M. Garcia-Diaz Identification of an intrinsic 5′-deoxyribose-5- phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair J. Biol. Chem. 276 2001 34659 34663
26. L. Aravind, and E.V. Koonin Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system Genome Res. 11 2001 1365 1374
27. A.J. Doherty Identification of bacterial homologues of the Ku DNA repair proteins FEBS Lett. 500 2001 186 188
28. M. Della Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine Science 306 2004 683 685
29. G.R. Weller Identification of a DNA nonhomologous end-joining complex in bacteria Science 297 2002 1686 1689
30. H. Zhu, and S. Shuman A primer-dependent polymerase function of Pseudomonas aeruginosa ATP-dependent DNA ligase (LigD) J. Biol. Chem. 280 2005 418 427
31. C. Gong Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C Nat. Struct. Mol. Biol. 12 2005 304 312