Alternative mode of binding to phosphotyrosyl peptides by Src homology-2 domains

Biochemistry

Volumn 44, Issue 36, 2005, Pages 12196-12202

  Qin, Chuanguang ^a   Wavreille, Anne Sophie ^a   Pei, Dehua ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; PROTEINS;

HOMOLOGY; LIGANDS; PHOSPHATASES;

POLYPEPTIDES;

PEPTIDE; PHOSPHATASE; PHOSPHOTYROSINE; PROTEIN SH2; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; RESIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ASSAY; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONSENSUS SEQUENCE; DISSOCIATION CONSTANT; ENZYME ACTIVITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; ENZYME ACTIVATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PEPTIDE LIBRARY; PHOSPHOPEPTIDES; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEIN-TYROSINE-PHOSPHATASE; SHP1 PROTEIN TYROSINE PHOSPHATASE; SRC HOMOLOGY DOMAINS;

EID: 24644434907     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050669o     Document Type: Article

References (21)

1. Pawson, T., and Nash, P. (2003) Assembly of cell regulatory systems through protein interaction domains, Science 300, 445-452.
2. Venter, J. C., et al. (2001) The sequence of the human genome, Science 291, 1304-1351.
3. Songyang, Z., Shoelson, S. E., Chaudhuri, M., Gish, G., Pawson, T., Haser, W. G., King, F., Roberts, T., Ratnofsky, S., Lechleider, R., J., Neel, B., G., Birge, R., B., Fajardo, J., E., Chou, M., M., Hanafusa, H., Schaffhausen, B., and Cantley, L., C. (1993) SH2 domains recognize specific phosphopeptide sequences, Cell 72, 767-778.
4. Waksman, G., Kominos, D., Robertson, S. C., Pant, N., Baltimore, D., Birge, R. B., Cowburn, D., Hanafusa, H., Mayer, B. J., Overduin, M., Resh, M. D., Rios, C. B., Silverman, L., and Kuriyan, J. (1992) Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides, Nature 358, 646-653.
5. Eck, M. J., Atwell, S. K., Shoelson, S. E., and Harrison, S. C. (1994) Structure of the regulatory domains of the Src-family tyrosine kinase Lck, Nature 368, 764-769.
6. Lee, C.-H., Kominos, D., Jacques, S., Margolis, B., Schlessinger, J., Shoelson, S. E., and Kuriyan, J. (1994) Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase, Structure 2, 423-438.
7. Burshtyn, D. N., Yang, W., Yi, T., and Long, E. O. (1997) A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of tyrosine phosphatase SHP-1, J. Biol. Chem. 272, 13066-13072.
8. Beebe, K. D., Wang P., Arabaci G., and Pei D. (2000) Determination of binding specificity of the SH2 domains of protein tyrosine phosphatase SHP-1 through the screening of a combinatorial phosphotyrosyl peptide library, Biochemistry 39, 13251-13260.
9. Poy, F., Yaffe, M. B., Sayos, J., Saxena, K., Morra, M., Sumegi, J., Cantley, L. C., Terhorst, C., and Eck, M. J. (1999) Crystal-structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition, Mol. Cell 4, 555-561.
10. Yan, K. S., Kuti, M., and Zhou, M.-M. (2002) PTB or not PTB-that is the question, FEBS Lett. 513, 67-70.
11. Pei, D., Lorenz, U., Klingmuller, U., Neel, B. G., and Walsh, C. T. (1994) Intramolecular regulation of protein tyrosine phosphatase SH-PTP1: a new function for Src homology 2 domains, Biochemistry 33, 15483-15493.
12. Pei, D., Wang, J., and Walsh, C. T. (1996) Differential functions of the two Src homology 2 domains in protein tyrosine phosphatase SH-PTP1, Proc. Natl. Acad. Sci. U.S.A. 93, 1141-1145.
13. Sweeney, M. C., Park, J., and Pei, D. (2005) Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-2 and SHIP SH2 domains, Biochemistry, submitted for publication.
14. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem. 72, 248-254.
15. Houghten, R. A., Pinilla, C., Blondelle, S. E., Appel, J. R., Dooley, C. T., and Cuervo, J. H. (1991) Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery, Nature 354, 84-86.
16. Lam, K. S., Salmon, S. E., Hersh, E. M., Hruby, V. J., Kazmierski, W. M., and Knapp, R. J. (1991) A new type of synthetic peptide library for identifying ligand-binding activity, Nature 354, 82-84.
17. Furka, A., Sebestyen, F., Asgedom, M., and Dibo, G. (1991) General method for rapid synthesis of multicomponent peptide mixtures, Int. J. Pept. Protein Res. 37, 487-493.
18. Sweeney, M. C., and Pei, D. (2003) An improved method for rapid sequencing of support-bound peptides by partial Edman degradation and mass spectrometry, J. Comb. Chem. 5, 218-222.
19. Lanzetta, P. A., Alvarez, L. J., Reinach, P. S., and Candia, O. A. (1979) An improved assay for nanomole amounts of inorganic phosphate, Anal. Biochem. 100, 95-97.
20. Liao, H., Yuan, C., Su, M.-I., Yongkiettrakul, S., Qin, D., Li, H., Byeon, I.-J. L., Pei, D., and Tsai, M.-D. (2000) Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9, J. Mol. Biol. 304, 941-951.
21. Pluskey, S., Wandless, T. J., Walsh, C. T., and Shoelson, S. E. (1995) Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains, J. Biol. Chem. 270, 2897-2900.