Synthesis of thiol-reactive lipopeptide adjuvants. Incorporation into liposomes and study of their mitogenic effect on mouse splenocytes

Bioconjugate Chemistry

Volumn 15, Issue 3, 2004, Pages 541-553

  Roth, Audrey ^a   Espuelas, Socorro ^a,b   Thumann, Christine ^c   Frisch, Benoît ^a   Schuber, Francis ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY OF NAVARRA   (Spain)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHAINS; CHEMICAL ACTIVATION; EMULSIFICATION; EPITOPES; LIPOSOMES; MAMMALS; PEPTIDES; T-CELLS;

AMPHIPATHIC; IMMUNOADJUVANTS; LIPOPEPTIDES; LYMPHOCYTE ACTIVATION; MITOGENIC EFFECTS; N-TERMINAL DOMAINS; PEPTIDE EPITOPES; PROTEIN ANTIGENS; SPLENOCYTES; SYNTHETIC ANALOGUES;

VACCINES;

ANTIGEN; EPITOPE; IMMUNOLOGICAL ADJUVANT; LIPOPEPTIDE; LIPOSOME; S [2,3 BIS(PALMITOYLOXY)PROPYL] N PALMITOYLCYSTEINYLALANYLGLYCINE; THIOL; THYMIDINE; TRITIUM; UNCLASSIFIED DRUG; VACCINE; [2,3 BIS(PALMITOYLOXY)PROPYL]CYSTEINYLALANYLGLYCINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; DNA SYNTHESIS; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; EMULSION; FEMALE; LYMPHOCYTE ACTIVATION; MITOGENESIS; MOUSE; MOUSE STRAIN; NONHUMAN; PROTEIN DOMAIN; SPLEEN CELL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VACCINATION;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 2442714271     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc034184t     Document Type: Article

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