Spin pH and SH probes: Enhancing functionality of EPR-based techniques

Spectroscopy

Volumn 18, Issue 2, 2004, Pages 213-225

  Khramtsov, Valery V ^a,b   Grigor'ev, Igor A ^c   Lurie, David J ^d   Foster, Margaret A ^d   Zweier, Jay L ^a   Kuppusamy, Periannan ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b INSTITUTE OF CHEMICAL KINETICS AND COMBUSTION   (Russian Federation)

^c N N VOROZHTSOV NOVOSIBIRSK INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MATHEMATICAL MODELS; NITROGEN COMPOUNDS; PARAMAGNETIC RESONANCE; PH EFFECTS; POLARIZATION;

BIOLOGICAL SYSTEMS; PROTON ELECTRON DOUBLE-RESONANCE IMAGING (PEDRI); SPECTRAL-SPATIAL IMAGING; SPIN PROBES;

BIOMEDICAL ENGINEERING;

AMPLITUDE MODULATION; CHEMICAL REACTION; CONFERENCE PAPER; ELECTRON SPIN RESONANCE; EVALUATION; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; IN VIVO STUDY; MOLECULAR PROBE; PH MEASUREMENT; SENSITIVITY ANALYSIS; SPIN LABELING; TECHNIQUE;

EID: 2442700169     PISSN: 07124813     EISSN: None     Source Type: Journal    
DOI: 10.1155/2004/870630     Document Type: Conference Paper

References (45)

1. L.J. Berliner and H. Fujii, Magnetic resonance imaging of biological specimens by electron paramagnetic resonance of nitroxide spin labels, Science 227 (1985), 517-519.
2. P. Kuppusamy, H. Li, G. Ilangovan, A.J. Cardounel, J.L. Zweier, K. Yamada, M.C. Krishna and J.B. Mitchell, Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels, Cancer Res. 62 (2002), 307-312.
3. H. Fujii and L.J. Berliner, In vivo EPR evidence for free radical adducts of nifedipine, Magn. Reson. Med. 42 (1999), 691-694.
4. N. Khan and H. Swartz, Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy, Mol. Cell Biochem. 234-235 (2002), 341-357.
5. A. Sotgiu, K. Mäder, G. Placidi, S. Colacicchi, C.L. Ursini and M. Alecci, pH-sensitive imaging by low-frequency EPR: a model study for biological applications, Phys. Med. Biol. 43 (1998), 1921-1930.
6. P. Gallo, S. Colacicchi, M. Ferrari, G. Gualtieri and A. Sotgiu, Electron paramagnetic resonance spectroscopy on isolated rat heart: a technical note, Cardioscience 2 (1991), 221-224.
7. D.J. Lurie, Free radical imaging, Br. J. Radiol. 74 (2001), 782-784.
8. V.V. Khramtsov, I.A. Grigor'ev, M.A. Foster, D.J. Lurie and I. Nicholson, Biological applications of spin pH probes, Cell. Mol. Biol. 46 (2000), 1361-1374.
9. I. Nicholson, F.J. Robb, S.J. McCallum, A. Koptioug and D.J. Lurie, Recent developments in combining LODESR imaging with proton NMR imaging, Phys. Med. Biol. 43 (1998), 1851-1855.
10. D.J. Lurie, H. Li, S. Petryakov and J.L. Zweier, Development of a PEDRI free-radical imager using a 0.38 T clinical MRI system, Magn. Reson. Med. 47 (2002), 181-186.
11. D.J. Lurie, M.A. Foster, D. Yeung and J.M. Hutchison, Design, construction and use of a large-sample field-cycled PEDRI imager, Phys. Med. Biol. 43 (1998), 1877-1886.
12. V.V. Khramtsov, New approaches in spin labeling and spin trapping. Part one: ESR studies of local chemical environment, in: Supramolecular Structure and Function 7, G. Pifat-Mrzljak, ed., Kluwer Academic/Plenum Publishers, New York, Boston, Dordrecht, London, Moscow, 2001, pp. 89-105.
13. J.I. Vandenberg, J.C. Metcalfe and A. Grace, Mechanisms of pHi recovery after global ischemia in the perfused heart, Circ. Res. 72 (1993), 993-1003.
14. G. Helmlinger, F. Yuan, M. Dellian and R.K. Jain, Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation, Nat. Med. 3 (1997), 177-182.
15. M. Thangaraju, K. Sharma, B. Leber, D.W. Andrews, S.H. Shen and C.B. Srikant, Regulation of acidification and apoptosis by SHP-1 and Bcl-2, J. Biol. Chem. 274 (1999), 29549-29557.
16. G. Ilangovan, H. Li, J.L. Zweier and P. Kuppusamy, In vivo measurement of tumor redox environment using EPR spectroscopy, Mol. Cell. Biochem. 234-235 (2002), 393-398.
17. U. Issberner, P.W. Reeh and K.H. Steen, Pain due to tissue acidosis: a mechanism for inflammatory and ischemic myalgia?, Neurosci. Lett. 208 (1996), 191-194.
18. S. Pietri, S. Martel, M. Culcasi, M.-C. Delmas-Beauvieux, P. Canioni and J.-L. Gallis, Use of diethyl(2-methylpyrrolidin-2-yl)phosphonate as a highly sensitive extra- and intracellular 31P NMR pH indicators in isolated organs, J. Biol. Chem. 276 (2001), 1750-1758.
19. R.J. Gillies, J.R. Alger, J.A. den Holander and R.G. Shulman, Intracellular pH measured by NMR: methods and results, in: Intracellular pH: Its Measurement, Regulation and Utilization in Cellular Functions, R. Nuccitelli and D.W. Deamer, eds, Alan R. Liss, New York, 1982, pp. 79-104.
20. B.S. Szwergold, NMR spectroscopy of cells, Annu. Rev. Physiol. 54 (1992), 775-798.
21. P. Lundberg, E. Harmsen, C. Ho and H.J. Vogel, Nuclear magnetic resonance studies of cellular metabolism, Anal. Biochem. 191 (1990), 193-222.
22. N with pH, J. Am. Chem. Soc. 104 (1982), 827-830.
23. V.V. Khramtsov, L.M. Weiner, I.A. Grigor'ev and L.B. Volodarsky, Proton exchange in stable nitroxyl radicals. EPR study of the pH of aqueous solutions, Chem. Phys. Lett. 91 (1982), 69-72.
24. V.V. Khramtsov, V.I. Yelinova, L.M. Weiner, T.A. Berezina, V.V. Martin and L.B. Volodarsky, Quantitative determination of SH groups in low- and high-molecular weight compounds by an ESR method, Anal. Biochem. 182 (1989), 58-63.
25. V.V. Khramtsov, V.I. Yelinova, Yu.I. Glazachev, V.A. Reznikov and G. Zimmer, Quantitative determination and reversible modification of thiols using imidazolidine biradical disulfide label, J. Biochem. Biophys. Methods 35 (1997), 115-128.
26. L.B. Volodarsky, V.A. Reznikov and I.A. Grigor'ev, Chemical properties of heterocyclic nitroxides, in: Imidazoline Nitroxides, L.B. Volodarsky, ed., Boca Raton, 1988, pp. 29-76.
27. Yu.I. Glazachev, I.A. Grigor'ev, E.J. Reijerse and V.V. Khramtsov, EPR studies of 15N- and 2H-substituted pH-sensitive spin probes of imidazoline and imidazolidine types, Appl. Magn. Reson. 20 (2001), 489-505.
28. J.L. Zweier and P. Kuppusamy, Electron paramagnetic resonance measurements of free radicals in the intact beating heart: a technique for detection and characterization of free radicals in whole biological tissues, Proc. Natl. Acad. Sci. USA 85 (1988), 5703-5707.
29. P. Kuppusamy, M. Chzhan, A. Samouilov, P. Wang and J.L. Zweier, Mapping the spin-density and lineshape distribution of free radicals using 4D spectral-spatial EPR imaging, J. Magn. Reson. B 107 (1995), 116-125.
30. P. Kuppusamy, M. Chzhan and J.L. Zweier, Development and optimization of three-dimensional spatial EPR imaging for biological organs and tissues, J. Magn. Reson. B 106 (1995), 122-130.
31. P. Kuppusamy, M. Chzhan, K. Vij, M. Shteynbuk, D.J. Lefer, E. Giannella and J.L. Zweier, Three-dimensional spectral-spatial EPR imaging of free radicals in the heart: a technique for imaging tissue metabolism and oxygenation, Proc. Natl. Acad. Sci. USA 91 (1994), 3388-3392.
32. R.K. Woods, W.B. Hyslop, M.R.B. and P.C. Lauterbur, Image reconstruction, in: EPR Imaging and in vivo EPR, G.R. Eaton, S.S. Eaton and K. Ohno, eds, CRC Press, Boca Raton, 1991, pp. 91-117.
33. V.V. Khramtsov, L.M. Weiner, S.I. Eremenko, O.I. Belchenko, P.V. Schastnev, I.A. Grigor'ev and V.A. Rezníkov, Proton exchange in stable nitroxyl radicals of imidazoline and imidazolidine series, J. Magn. Reson. 61 (1985), 397-408.
34. M.A. Foster, I.A. Grigor'ev, D.J. Lurie, V.V. Khramtsov, S. McCallum, I. Panagiotelis, J.M.S. Hutchison, A. Koptioug and I. Nicholson, In vivo detection of a pH-sensitive nitroxide in the rat stomach by low-field ESR-based techniques, Magn. Reson. Med. 49 (2003), 558-567.
35. K. Mäder, B. Gallez, K.J. Liu and H.M. Swartz, Non-invasive in vivo characterization of release processes in biodegradable polymers by low-frequency electron paramagnetic resonance spectroscopy, Biomaterials 17 (1996), 457-461.
36. B. Gallez, K. Mäder and H.M. Swartz, Noninvasive measurement of the pH inside the gut by using pH-sensitive nitroxides: An in vivo EPR study, Magn. Reson. Med. 36 (1996), 694-697.
37. C. Kroll, W. Hermann, R. Stosser, H.H. Borchert and K. Mäder, Influence of drug treatment on the microacidity in rat and human skin - an in vitro electron spin resonance imaging study, Pharm. Res. 18 (2001), 525-530.
38. A. Brunner, K. Mäder and A. Gopferich, pH and osmotic pressure inside biodegradable microspheres during erosion, Pharm. Res. 16 (1999), 847-853.
39. K. Mäder, B. Bittner, Y. Li, W. Wohlauf and T. Kissel, Monitoring microviscosity and microacidity of the albumin microenvironment inside degrading microparticles from poly(lactide-co-glycolide) (PLG) or ABA-triblock polymers containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly(ethyleneoxide) B blocks, Pharm. Res. 15 (1998), 787-793.
40. C. Kroll, K. Mäder, R. Stosser and H.H. Borchert, Direct and continuous determination of pH values in nontransparent w/o systems by means of EPR spectroscopy, Eur. J. Pharmaceut. Sci. 3 (1995), 21-26.
41. K. Mäder, S. Nitschke, R. Stosser and H.-H. Borchert, Non destructive and localized assessment of acidic microenvironments inside biodegradable polyanhydrides by specral spatial electron paramagnetic resonance imaging, Polymer 38 (1997), 4785-4794.
42. V.V. Khramtsov and L.B. Volodarsky, Use of imidazoline nitroxides in studies of chemical reactions: ESR measurements of concentration and reactivity of protons, thiols and nitric oxide, in: Biological Magnetic Resonance, Vol. 14: Spin Labeling: The Next Millennium, L.J. Berliner, ed., Plenum Press, New York and London, 1998, pp. 109-180.
43. M. Voinov and I.A. Grigor'ev, in: 3rd International Conference on Nitroxide Radicals, Kaiserslautern, Germany, 2001, p.110.
44. L. Hagenfeldt, A. Arvidsson and A. Larsson, Glutathione and -glutamylcysteine in whole blood, plasma and erythrocytes, Clin. Chim. Acta 85 (1978), 167-173.
45. A.F. Boyne and G.L. Ellman, A methodology for analysis of tissue sulfhydryl components, Anal. Biochem. 46 (1972), 639-653.