Alveolar Macrophages Autoregulate IL-1 and IL-6 Production by Endogenous Nitric Oxide

American Journal of Respiratory Cell and Molecular Biology

Volumn 14, Issue 3, 1996, Pages 272-278

  Persoons, Jek H A ^a   Schornagel, Karin ^b   Tilders, Fred F H ^b   De Vente, Jan ^b   Berkenbosch, Frank ^b   Kraal, Georg ^b  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; DRUG DERIVATIVE; ENZYME INHIBITOR; INTERLEUKIN 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; N ACETYL S NITROSOPENICILLAMINE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PENICILLAMINE; SODIUM NITRITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; DRUG ANTAGONISM; HOMEOSTASIS; IMMUNOLOGY; LUNG ALVEOLUS MACROPHAGE; MALE; PHYSIOLOGY; RAT; WISTAR RAT;

ANIMALS; ARGININE; CELLS, CULTURED; ENZYME INHIBITORS; HOMEOSTASIS; INTERLEUKIN-1; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OMEGA-N-METHYLARGININE; PENICILLAMINE; RATS; RATS, WISTAR; S-NITROSO-N-ACETYLPENICILLAMINE; SODIUM NITRITE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030096215     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.14.3.8845178     Document Type: Article

References (54)

1. Unanue, E. 1989. Macrophages, antigen presenting cells, and the phenomena of antigen handling and presentation. In Fundamental Immunology. W. E. Paul, editor. Raven Press, New York. 95-115.
2. Murray, H. W. 1991. Interferon-τ, cytokine-induced macrophage activation, and antimicrobial defense: in vitro, in animal models and in man. Diagn. Microbiol. Infect. Dis. 13:411-421.
3. Bogdan, C., and C. F. Nathan. 1993. Modulation of macrophage function by transforming growth factor β, interleukin-4 and interleukin-10. Ann. NY Acad. Sci. 685:713-739.
4. Nathan, C. F. 1987. Secretory products of macrophages. J. Clin. Invest. 79:319-326.
5. Nathan, C. F. 1994. Coordinate actions of growth factors in monocytes/macrophages. In Handbook of Experimental Pharmacology, Vol. 95/II. M. B. Sporn and A. B. Roberts, editors. Springer Verlag, Berlin/Heidelberg. 427-462.
6. Arend, W. P., M. F. Smith, R. W. Janson, and F. G. Joslin. 1991. IL-1 receptor antagonist and IL-1β production in human monocytes are regulated differently. J. Immunol. 147:1526-1530.
7. Ding, A. H., E. Sanchez, S. Srimal, and C. F. Nathan. 1989. Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharide. J. Biol. Chem. 264:3924-3929.
8. Engelmann, H. D., M. Aderka, M. Rubinstein, D. Rotman, and D. Wallach. 1989. A tumor necrosis factor binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity. J. Biol. Chem. 264:11974-11980.
9. Gatanaga, T., R. Lentz, I. Masunaka, J. Tomich, III, E. W. B. Jeffes, M. Baird, and G. A. Granger. 1990. Identification of TNF-LT blocking factor(s) in the serum and ultrafiltrates of human cancer patients. Lymphokine Res. 9:225-229.
10. Peleman, R., J. Wu, C. Fargeas, and G. Delespesse. 1989. Recombinant interleukin 4 suppresses the production of interferon τ by human mononuclear cells. J. Exp. Med. 170:1751-1756.
11. Fiorentino, D. F., M. W. Bond, and T. R. Mosmann. 1989. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 170:2081-2095.
12. Hsu, D.-H., K. W. Moore, and H. Spits. 1992. Differential effects of IL-4 and IL-10 on IL-2 induced IFN-τ synthesis and lymphokine-activated killer activity. Int. Immunol. 4:563-569.
13. 2. Am. Rev. Respir. Dis. 135:72-77.
14. 2 inhibits the release of tumor necrosis factor-α, rather than interleukin-1β from human macrophages. Immunol. Lett. 31:85-90.
15. Fiorentino, D. F., A. Zlotnik, T. R. Mosmann, M. Howard, and A. O'Garra. 1991. IL-10 inhibts cytokine production by activated macrophages. J. Immunol. 147:3815-3822.
16. Persoons, J. H. A., K. Schornagel, J. Brevé, F. Berkenbosch, and G. Kraal. 1995. Acute stress affects cytokines and NO production by alveolar macrophages differently. Am. J. Respir. Crit. Care Med. 152:619-624.
17. Derijk, R., N. van Rooijen, F. J. H. Tilders, H. O. Besedovsky, A. Del Rey, and F. Berkenbosch. 1991. Selective depletion of macrophages prevents pituitary-adrenal activation in response to subpyrogenic, but not to pyrogenic, doses of bacterial endotoxin in rats. Endocrinology 129:330-338.
18. Holt, P. G., J. E. Batty, and K. J. Turner. 1981. Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen. Immunol. 42: 409-417.
19. Flick, D. A. and G. E. Gifford. 1984. Comparison of in vitro cell cytotoxic assays for tumor necrosis factor. J. Immunol. Methods 68:167-175.
20. Ding, A. H., C. F. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. J. Immunol. 141:2407-2412.
21. Twentyman, P. R., and M. Luscombe. 1987. A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity. Br. J. Cancer 56:279-285.
22. Stadler, J., B. G. Harbrecht, M. Di Silvio, R. D. Curran, M. L. Jordan, R L. Simmons, and T. R. Billiar. 1993. Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells. J. Leukocyte Biol. 53:165-172.
23. Tilders, F. J. H., R. H. DeRijk, A.-M. Van Dam, V. A. M. Vincent, K. Schotanus, and J. H. A. Persoons. 1994. Activation of the hypothalamus-pituitary-adrenal axis by bacterial endotoxins: routes and intermediate signals. Psychoneuroendocrinology 19:209-232.
24. Eisenberg, S. P., R. J. Evans, W. P. Arend, E. Verderber, M. T. Brewer, C. H. Hannum, and R. C. Thompson. 1990. Primary structure and functional expression from complementary cDNA of a human IL-1 receptor antagonist. Nature 343:341-346.
25. Hannum, C. H., C. J. Wilcox, W. P. Arend, F. G. Joslin, D. J. Dripps, P. L. Heimdahl, L. G. Armes, A. Sommer, S. P. Eisenberg, and R. C. Thompson. 1990. IL-1 receptor antagonist activity of a human IL-1 inhibitor. Nature 343:336-340.
26. Marletta, M. A., P. S. Yoon, R. Iyengar, C. D. Leaf, and J. S. Wishnok. 1988. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. Biochemistry 27:8706-8711.
27. Hart, P. H., G. A. Whitty, D. S. Picolly, and J. A. Hamilton. 1988. Synergistic activation of human monocytes by granulocyte-macrophage colony stimulating factor and IFN-τ. Increased TNF-α but not IL-1 activity. J. Immunol. 141:1516.
28. Riesenfeld-Orn, I., S. Wolpe, J. F. Garcia-Bustos, M. K. Hoffman, and E. Tuomanen. 1989. Production of interleukin-1 but not tumor necrosis factor by human monocytes stimulated with pneumococcal cell surface components. Infect. Immun. 57:1890.
29. Zuckerman, S. H., G. F. Evans, and L. Guthrie. 1991. Transcriptional and post-transcriptional mechanisms involved in the differential expression of LPS-induced IL-1 and TNF mRNA. Immunology 73:460-465.
30. Tucker, S. D., M. R. Sivaramakrishnan, J. Klostergaard, and G. Lopez-Berestein. 1991. Independence of the pattern of early cytokine release from autoregulation by nitric oxide. J. Leukoc. Biol. 50:509-516.
31. Albina, J. E., C. D. Mills, W. L. Henry, Jr., and M. D. Caldwell. 1989. Regulation of macrophage physiology by L-arginine: role of the oxidative L-arginine deiminase pathway. J. Immunol. 143:3641-3646.
32. Stadler, J., T. R. Billiar, R. D. Curran, D. J. Stuehr, J. B. Ochoa, and R. L. Simmons. 1991. Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. Am. J. Physiol. 260:C910-C916.
33. Stuehr, D. J., and C. F. Nathan. 1989. Nitric oxide; a macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J. Exp. Med. 169:1543-1555.
34. Granger, D. L., and A. L. Lehninger. 1982. Sites of inhibition of mitochondrial electron transport in macrophage-injured neoplastic cells. J. Cell Biol. 95:527-535.
35. Curran, R. D., F. K. Ferrari, P. H. Kispert, J. Stadler, D. J. Stuehr, R. L. Simmons, and T. R. Billiar. 1991. Nitric oxide and nitric oxide-generating compounds inhibit hepatocyte protein synthesis. FASEB J. 5:2085-2092.
36. Billiar, T. R., R. D. Curran, D. J. Stuehr, M. A. West, B. G. Bentz, and R. L. Simmons. 1989. An l-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. J. Exp. Med. 169:1467-1472.
37. Waldman, S. A., and F. Murad. 1987. Cyclic GMP synthesis and function. Pharmacol. Rev. 39:163-196.
38. 2 and cyclic CMP. Immunobiology 182:44-55.
39. Holt, P. G., J. Oliver, N. Bilyk, C. McMenamin, P. G. McMenamin, G. Kraal, and T. Thepen. 1993. Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. J. Exp. Med. 177:397-407.
40. Dinarello, C. A. Cytokine therapy: 1993. Modalities for reducing interleukin-1 activity in disease. Trends Pharmacol. Sci. 14:155-159.
41. Plebanski, M., C. J. Elson, and W. D. Billington. 1992. Dependency on interleukin-1 of primary human in vitro T cell responses to soluble antigens. Eur. J. Immunol. 22:2353-2358.
42. Rotteveel, F. T. M., M. H. A. M. Verhouf, R. Derijk, H. Van Den Bergh, D. A. W. Wolvers, and F. Berkenbosch. 1991. Both interleukin-α and interleukin-β are involved as accessory signals in primary antigen (tetanus toxoid) induced human T-cell activation. Cell. Immunol. 138:245-250.
43. Oppenheim, J. J., E. J. Kovacs, K. Matsushima, and S. K. Durum. 1986. There is more than one interleukin-1. Immunol. Today 7:45-46.
44. Thepen, T., N. Van Rooijen, and G. Kraal. 1989. Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice. J. Exp. Med. 170:499-509.
45. Thepen, T., C. McMenamin, B. Girn, G. Kraal, and P. G. Holt. 1992. Regulation of IgE production in pre-sensitized animals: in vivo elimination of alveolar macrophages preferentially increases IgE responses to inhaled allergen. Clin. Exp. Allergy 22:1107-1114.
46. Strickland, D. H., T. Thepen, U. R. Kees, G. Kraal, and P. G. Holt. 1993. Regulation of T-cell function in lung tissue by pulmonary alveolar macrophages. Immunology 80:266-272.
47. Gustafsson, L. E., A. M. Leone, M. G. Persson, N. P. Wiklund, and S. Moncada. 1991. Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans. Biochem. Biophys. Res. Commun. 181: 852-857.
48. Lee, T. H., R. Poston, P. Godard, and J. Bousquet. 1991. Macrophages and allergic asthma. Clin. Exp. Allergy 21(Suppl. 1):22-23.
49. Kay, A. B. 1991. Asthma and inflammation. J. Allergy Clin. Immunol. 87: 893-910.
50. Borish, L., J. J. Mascali, J. Dishuck, W. R. Beam, R. J. Martin, and L. J. Rosenwasser. 1992. Detection of alveolar macrophage-derived IL-1β in asthma. J. Immunol. 149:3078-3082.
51. Hogaboam, C. M., A. D. Befus, and J. L. Wallace. 1993. Modulation of rat mast cell reactivity by IL-1β. J. Immunol. 151:3767-3774.
52. Bluthe, R. M., S. Sparber, and R. Dantzer. 1992. Modulation of the behavioural effects of interleukin-1 in mice by nitric oxide. Neuroreport 3: 207-209.
53. Lee, S. C., W. Liu, D. W. Dickson, C. F. Brosnan, and J. W. Berman. 1993. Cytokine production by human fetal microglia and astrocytes. J. Immunol. 150:2659-2667.
54. Bauer, J., F. Berkenbosch, A.-M. Van Dam, and C. D. Dijkstra. 1993. Demonstration of interleukin-1β in Lewis rat brain during experimental allergic encephalomyelitis by immunocytochemistry at the light and ultrastructural level. J. Neuroimmunol. 48:13-22.