Generation of Leishmania mutants lacking antibiotic resistance genes using a versatile hit-and-run targeting strategy

FEMS Microbiology Letters

Volumn 235, Issue 1, 2004, Pages 89-94

  Denise, Hubert ^a   Coombs, Graham H ^b   Mottram, Jeremy C ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Attentuation; Genetic manipulation; Leishmania; Mutants; Peptidase

Indexed keywords

DNA;

ALLELE; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; CYSTEINE PEPTIDASE GENE; GENE; GENE CASSETTE; GENE LOCUS; GENE TARGETING; GENETIC MARKER; HYGROMYCIN RESISTANCE GENE; LEISHMANIA; LEISHMANIA INFANTUM; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; THYMIDINE KINASE GENE;

ANIMALS; CINNAMATES; CYSTEINE ENDOPEPTIDASES; DRUG RESISTANCE; GENE DELETION; GENES, PROTOZOAN; GENETIC ENGINEERING; HYGROMYCIN B; LEISHMANIA; PLASMIDS; PROMOTER REGIONS (GENETICS); RNA, RIBOSOMAL, 18S; THYMIDINE KINASE;

LEISHMANIA INFANTUM;

EID: 2442673039     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsle.2004.04.015     Document Type: Article

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