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Volumn 286, Issue 6 49-6, 2004, Pages

Regulation by glucose and calcium of the carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting INS-1 cells

Author keywords

Glucose metabolism; Insulin secreting cells

Indexed keywords

CALCIUM; CITRIC ACID; DIAZOXIDE; GLUCOSE; INSULIN; MANNOHEPTULOSE; PHOSPHOENOLPYRUVATE; PHOSPHOPROTEIN PHOSPHATASE 2A; POTASSIUM CHLORIDE;

EID: 2442648045     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00587.2003     Document Type: Article
Times cited : (22)

References (47)
  • 1
    • 0028205382 scopus 로고
    • Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells
    • Ammala C, Eliasson L, Bokvist K, Berggren PO, Honkanen RE, Sjoholm A, and Rorsman P. Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells. Proc Natl Acad Sci USA 91: 4343-4347, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4343-4347
    • Ammala, C.1    Eliasson, L.2    Bokvist, K.3    Berggren, P.O.4    Honkanen, R.E.5    Sjoholm, A.6    Rorsman, P.7
  • 2
    • 0029885298 scopus 로고    scopus 로고
    • Phosphatase inhibitor okadaic acid blocks KCl-depolarization induced rise of cytosolic calcium of rat insulinoma cells (Rin m5F)
    • Ammon HP, Heurich RO, Kolb HA, Lang F, Schaich R, Drews G, and Leiers T. Phosphatase inhibitor okadaic acid blocks KCl-depolarization induced rise of cytosolic calcium of rat insulinoma cells (Rin m5F). Naunyn-Schmiedeber's Arch Pharmacol 354: 95-101, 1996.
    • (1996) Naunyn-Schmiedeber's Arch Pharmacol , vol.354 , pp. 95-101
    • Ammon, H.P.1    Heurich, R.O.2    Kolb, H.A.3    Lang, F.4    Schaich, R.5    Drews, G.6    Leiers, T.7
  • 4
    • 0027941213 scopus 로고
    • Protein phosphorylation and beta-cell function
    • Ashcroft SJH. Protein phosphorylation and beta-cell function. Diabetologia 37, Suppl 2: S21-S29, 1994.
    • (1994) Diabetologia , vol.37 , Issue.SUPPL. 2
    • Ashcroft, S.J.H.1
  • 5
    • 0023299933 scopus 로고
    • NADP-linked dismutation and concentrations of citrate, cytosolic free calcium and phosphoenolpyruvate in islet B-cells stimulated with glucose
    • Boquist L. NADP-linked dismutation and concentrations of citrate, cytosolic free calcium and phosphoenolpyruvate in islet B-cells stimulated with glucose. Biochem Int 14: 531-538, 1987.
    • (1987) Biochem Int , vol.14 , pp. 531-538
    • Boquist, L.1
  • 6
    • 0033560729 scopus 로고    scopus 로고
    • Methylated C-terminal leucine residue of PP2A catalytic subunit is important for binding of regulatory B (α) subunit
    • Bryant JC, Westphal RS, and Wadzinski BE. Methylated C-terminal leucine residue of PP2A catalytic subunit is important for binding of regulatory B (α) subunit. Biochem J 339: 241-246, 1999.
    • (1999) Biochem J , vol.339 , pp. 241-246
    • Bryant, J.C.1    Westphal, R.S.2    Wadzinski, B.E.3
  • 7
    • 0026786471 scopus 로고
    • Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation
    • Chen J, Mortin BL, and Brautigan DL. Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation. Science 257: 1261-1264, 1992.
    • (1992) Science , vol.257 , pp. 1261-1264
    • Chen, J.1    Mortin, B.L.2    Brautigan, D.L.3
  • 8
    • 0024397415 scopus 로고
    • The structure and regulation of protein phosphatases
    • Cohen P. The structure and regulation of protein phosphatases. Annu Rev Biochem 58: 453-508, 1989.
    • (1989) Annu Rev Biochem , vol.58 , pp. 453-508
    • Cohen, P.1
  • 10
    • 0035853846 scopus 로고    scopus 로고
    • Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction
    • Cruz WS, Kwon G, Marshall CA, McDaniel ML, and Semenkovich CF. Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction. J Biol Chem 276: 12162-12168, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 12162-12168
    • Cruz, W.S.1    Kwon, G.2    Marshall, C.A.3    McDaniel, M.L.4    Semenkovich, C.F.5
  • 11
    • 0024998368 scopus 로고
    • Effects of insulin secretagogues on protein kinase C-catalyzed phosphorylation of an endogenous substrate in isolated pancreatic islets
    • Easom RA, Landt M, Colca JR, Hughes JH, Turk J, and McDaniel M. Effects of insulin secretagogues on protein kinase C-catalyzed phosphorylation of an endogenous substrate in isolated pancreatic islets. J Biol Chem 265: 14938-14946, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 14938-14946
    • Easom, R.A.1    Landt, M.2    Colca, J.R.3    Hughes, J.H.4    Turk, J.5    McDaniel, M.6
  • 12
    • 0028361380 scopus 로고
    • The catalytic subunit of protein phosphatase 2A is carboxy methylated in vivo
    • Favre B, Zolnierowicz S, Turowski P, and Hemmings BA. The catalytic subunit of protein phosphatase 2A is carboxy methylated in vivo. J Biol Chem 269: 16311-16317, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 16311-16317
    • Favre, B.1    Zolnierowicz, S.2    Turowski, P.3    Hemmings, B.A.4
  • 15
    • 0034006587 scopus 로고    scopus 로고
    • Isolation of INS-1 derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion
    • Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, and Newgard CB. Isolation of INS-1 derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion. Diabetes 49: 424-430, 2000.
    • (2000) Diabetes , vol.49 , pp. 424-430
    • Hohmeier, H.E.1    Mulder, H.2    Chen, G.3    Henkel-Rieger, R.4    Prentki, M.5    Newgard, C.B.6
  • 16
    • 0032459512 scopus 로고    scopus 로고
    • Protein kinases, protein phosphorylation and the regulation of insulin secretion from pancreatic beta-cells
    • Jones PM and Persaud SJ. Protein kinases, protein phosphorylation and the regulation of insulin secretion from pancreatic beta-cells. Endocr Rev 19: 429-461, 1998.
    • (1998) Endocr Rev , vol.19 , pp. 429-461
    • Jones, P.M.1    Persaud, S.J.2
  • 17
    • 0029793537 scopus 로고    scopus 로고
    • Glucose-induced tyrosine phosphorylation of p 125 in beta cells and pancreatic islets. A novel proximal signal in insulin secretion
    • Konrad RJ, Dean RM, Young RA, Billings PC, and Wolf BA. Glucose-induced tyrosine phosphorylation of p125 in beta cells and pancreatic islets. A novel proximal signal in insulin secretion. J Biol Chem 271: 24179-24186, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 24179-24186
    • Konrad, R.J.1    Dean, R.M.2    Young, R.A.3    Billings, P.C.4    Wolf, B.A.5
  • 18
    • 0035406952 scopus 로고    scopus 로고
    • Activation of acetyl-CoA carboxylase by a glutamate and magnesium-sensitive protein phosphatase in the islet β-cell
    • Kowluru A, Chen HQ, Modrick LM, and Stefanelli C. Activation of acetyl-CoA carboxylase by a glutamate and magnesium-sensitive protein phosphatase in the islet β-cell. Diabetes 50: 1580-1587, 2001.
    • (2001) Diabetes , vol.50 , pp. 1580-1587
    • Kowluru, A.1    Chen, H.Q.2    Modrick, L.M.3    Stefanelli, C.4
  • 19
    • 0030868819 scopus 로고    scopus 로고
    • Glucose activates the carboxyl methylation of γ-subunit of trimeric GTP binding proteins in pancreatic β-cells
    • Kowluru A, Li G, and Metz SA. Glucose activates the carboxyl methylation of γ-subunit of trimeric GTP binding proteins in pancreatic β-cells. J Clin Invest 100: 1596-1610, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 1596-1610
    • Kowluru, A.1    Li, G.2    Metz, S.A.3
  • 20
    • 0021250412 scopus 로고
    • Glucose-induced, calcium-mediated phosphorylation in intact pancreatic islets
    • Kowluru A and MacDonald MJ. Glucose-induced, calcium-mediated phosphorylation in intact pancreatic islets. Arch Biochem Biophys 231: 320-327, 1984.
    • (1984) Arch Biochem Biophys , vol.231 , pp. 320-327
    • Kowluru, A.1    MacDonald, M.J.2
  • 21
    • 0028023248 scopus 로고
    • Subcellular localization and kinetic characterization of guanine nucleotide binding proteins in normal rat and human islets and transformed beta-cells
    • Kowluru A, Rabaglia ME, Muse K, and Metz SA. Subcellular localization and kinetic characterization of guanine nucleotide binding proteins in normal rat and human islets and transformed beta-cells. Biochem Biophys Acta 1222: 348-359, 1994.
    • (1994) Biochem Biophys Acta , vol.1222 , pp. 348-359
    • Kowluru, A.1    Rabaglia, M.E.2    Muse, K.3    Metz, S.A.4
  • 22
    • 0028831942 scopus 로고
    • Non-specific stimulatory effects of mastoparan on pancreatic islet nucleoside diphosphokinase activity: Dissociation from insulin secretion
    • Kowluru A, Seavy SE, Rabaglia ME, and Metz SA. Non-specific stimulatory effects of mastoparan on pancreatic islet nucleoside diphosphokinase activity: dissociation from insulin secretion. Biochem Pharmacol 49: 263-266, 1995.
    • (1995) Biochem Pharmacol , vol.49 , pp. 263-266
    • Kowluru, A.1    Seavy, S.E.2    Rabaglia, M.E.3    Metz, S.A.4
  • 23
    • 0029887332 scopus 로고    scopus 로고
    • Carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting cells: Evidence for functional consequences on enzyme activity and insulin secretion
    • Kowluru A, Seavey SE, Rabaglia ME, Nesher R, and Metz SA. Carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting cells: evidence for functional consequences on enzyme activity and insulin secretion. Endocrinology 137: 2315-2323, 1996.
    • (1996) Endocrinology , vol.137 , pp. 2315-2323
    • Kowluru, A.1    Seavey, S.E.2    Rabaglia, M.E.3    Nesher, R.4    Metz, S.A.5
  • 24
    • 0030065070 scopus 로고    scopus 로고
    • A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells
    • Kowluru A, Seavey SE, Rhodes CJ, and Metz SA. A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells. Biochem J 313: 97-107, 1996.
    • (1996) Biochem J , vol.313 , pp. 97-107
    • Kowluru, A.1    Seavey, S.E.2    Rhodes, C.J.3    Metz, S.A.4
  • 26
    • 0027184102 scopus 로고
    • Protein phophatase 2A catalytic subunit is methyl esterified at its carboxyl terminus by a novel methyl transferase
    • Lee J and Stock J. Protein phophatase 2A catalytic subunit is methyl esterified at its carboxyl terminus by a novel methyl transferase, J Biol Chem 268: 19192-19195, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 19192-19195
    • Lee, J.1    Stock, J.2
  • 28
    • 0027364367 scopus 로고
    • Modulation of insulin secretion from normal rat islets by inhibitors of the post translational modifications of GTP-binding proteins
    • Metz SA, Rabaglia ME, Stock JB, and Kowluru A. Modulation of insulin secretion from normal rat islets by inhibitors of the post translational modifications of GTP-binding proteins. Biochem J 295: 31-40, 1993.
    • (1993) Biochem J , vol.295 , pp. 31-40
    • Metz, S.A.1    Rabaglia, M.E.2    Stock, J.B.3    Kowluru, A.4
  • 29
    • 0025332734 scopus 로고
    • Protein phosphorylation in pancreatic islets induced by 3-phosphoglycerate and 2-phosphoglycerate
    • Pek SB, Usami M, Bilir N, Fischer-Bovenkerk C, and Ueda T. Protein phosphorylation in pancreatic islets induced by 3-phosphoglycerate and 2-phosphoglycerate. Proc Natl Acad Sci USA 87: 4294-4298, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4294-4298
    • Pek, S.B.1    Usami, M.2    Bilir, N.3    Fischer-Bovenkerk, C.4    Ueda, T.5
  • 30
    • 0032956915 scopus 로고    scopus 로고
    • Tyrosine kinases play a permissive role in glucose-induced insulin secretion from adult rat islets
    • Persaud SJ, Harris TE, Burns CJ, and Jones PM. Tyrosine kinases play a permissive role in glucose-induced insulin secretion from adult rat islets. J Mol Endocrinol 22: 19-28, 1999.
    • (1999) J Mol Endocrinol , vol.22 , pp. 19-28
    • Persaud, S.J.1    Harris, T.E.2    Burns, C.J.3    Jones, P.M.4
  • 31
    • 0027441369 scopus 로고
    • Effects of okadaic acid on insulin secretion from rat islets of Langerhans
    • Ratcliff H and Jones PM. Effects of okadaic acid on insulin secretion from rat islets of Langerhans. Biochem Biophys Acta 1175: 188-191, 1993.
    • (1993) Biochem Biophys Acta , vol.1175 , pp. 188-191
    • Ratcliff, H.1    Jones, P.M.2
  • 32
    • 0031718037 scopus 로고    scopus 로고
    • Interference of d-mannoheptulose with d-glucose phosphorylation, metabolism and functional effects: Comparison between liver, parotid cells and pancreatic islets
    • Scruel O, vanhoutte C, Sener A, and Malaisse WJ. Interference of d-mannoheptulose with d-glucose phosphorylation, metabolism and functional effects: comparison between liver, parotid cells and pancreatic islets. Mol Cell Biochem 187: 113-120, 1998.
    • (1998) Mol Cell Biochem , vol.187 , pp. 113-120
    • Scruel, O.1    Vanhoutte, C.2    Sener, A.3    Malaisse, W.J.4
  • 33
    • 0031751897 scopus 로고    scopus 로고
    • Aspects of novel sites of regulation of the insulin stimulus-secretion coupling in normal and diabetic pancreatic islets
    • Sjoholm A. Aspects of novel sites of regulation of the insulin stimulus-secretion coupling in normal and diabetic pancreatic islets. Endocrine 9: 1-13, 1998.
    • (1998) Endocrine , vol.9 , pp. 1-13
    • Sjoholm, A.1
  • 34
    • 0034810151 scopus 로고    scopus 로고
    • Effects of second messengers on serine-threonine protein phosphatases in insulin-secreting cells
    • Sjoholm A, Berggren PO, and Honkanen RE. Effects of second messengers on serine-threonine protein phosphatases in insulin-secreting cells. Biochem Biophys Res Commun 283: 364-368, 2001.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 364-368
    • Sjoholm, A.1    Berggren, P.O.2    Honkanen, R.E.3
  • 35
    • 0343986297 scopus 로고    scopus 로고
    • Polyamines regulate serine/threonine protein phosphatases in insulin secreting cells
    • Sjoholm A and Honkanen RE. Polyamines regulate serine/threonine protein phosphatases in insulin secreting cells. Pancreas 20: 32-37, 2000.
    • (2000) Pancreas , vol.20 , pp. 32-37
    • Sjoholm, A.1    Honkanen, R.E.2
  • 36
    • 0027787952 scopus 로고
    • Characterization of serine/threonine protein phosphatases in RINm 5F insulinoma cells
    • Sjoholm A, Honkanen RE, and Berggren PO. Characterization of serine/threonine protein phosphatases in RINm5F insulinoma cells. Biosci Rep 13: 349-358. 1993.
    • (1993) Biosci Rep , vol.13 , pp. 349-358
    • Sjoholm, A.1    Honkanen, R.E.2    Berggren, P.O.3
  • 37
    • 0029164488 scopus 로고
    • Inhibition of serine-threonine protein phosphatases by secretagogues in insulin secreting cells
    • Sjoholm A, Honkanen RE, Berggren PO. Inhibition of serine-threonine protein phosphatases by secretagogues in insulin secreting cells. Endocrinology 136: 3391-3397, 1995.
    • (1995) Endocrinology , vol.136 , pp. 3391-3397
    • Sjoholm, A.1    Honkanen, R.E.2    Berggren, P.O.3
  • 38
    • 0036892130 scopus 로고    scopus 로고
    • Glucose metabolites inhibit protein phosphatases and directly promote insulin exocytosis in pancreatic beta-cells
    • Sjoholm A, Lehtihet M, Efanov AM, Zaitsev SV, Berggren PO, and Honkanen RE. Glucose metabolites inhibit protein phosphatases and directly promote insulin exocytosis in pancreatic beta-cells. Endocrinology 143: 4592-4598, 2002.
    • (2002) Endocrinology , vol.143 , pp. 4592-4598
    • Sjoholm, A.1    Lehtihet, M.2    Efanov, A.M.3    Zaitsev, S.V.4    Berggren, P.O.5    Honkanen, R.E.6
  • 39
    • 0017739643 scopus 로고
    • Phosphoenolpyruvate in rat pancreatic islets: A possible intracellulat trigger of insulin release
    • Sugden MC and Ashcroft SJH. Phosphoenolpyruvate in rat pancreatic islets: a possible intracellulat trigger of insulin release. Diabetologia 13: 481-486, 1977.
    • (1977) Diabetologia , vol.13 , pp. 481-486
    • Sugden, M.C.1    Ashcroft, S.J.H.2
  • 40
    • 0026732757 scopus 로고
    • Effects of protein phosphatase inhibitors okadaic acid and calyculin A on insulin release from rat pancreatic islets
    • Tamagawa T, Iguchi A, Uemura K, Miura H, and Nonogaki K. Effects of protein phosphatase inhibitors okadaic acid and calyculin A on insulin release from rat pancreatic islets. Endocrinol Jpn 39: 325-339, 1992.
    • (1992) Endocrinol Jpn , vol.39 , pp. 325-339
    • Tamagawa, T.1    Iguchi, A.2    Uemura, K.3    Miura, H.4    Nonogaki, K.5
  • 41
    • 0034331359 scopus 로고    scopus 로고
    • Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits
    • Tolstykh T, Lee J, Vafai S, and Stock JB. Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits. EMBO J 19: 5682-5691, 2000.
    • (2000) EMBO J , vol.19 , pp. 5682-5691
    • Tolstykh, T.1    Lee, J.2    Vafai, S.3    Stock, J.B.4
  • 42
    • 0029129557 scopus 로고
    • Serine/threonine protein phosphatases
    • Wera S and Hemmings BA. Serine/threonine protein phosphatases. Biochem J 311: 17-29, 1995.
    • (1995) Biochem J , vol.311 , pp. 17-29
    • Wera, S.1    Hemmings, B.A.2
  • 43
    • 0018696224 scopus 로고
    • Regulation of hepatic acetyl CoA carboxylase by insulin and glucagon
    • Witters LA, Moriarity D, and Martin DB. Regulation of hepatic acetyl CoA carboxylase by insulin and glucagon. J Biol Chem 254: 6644-6649, 1979.
    • (1979) J Biol Chem , vol.254 , pp. 6644-6649
    • Witters, L.A.1    Moriarity, D.2    Martin, D.B.3
  • 44
    • 0034331296 scopus 로고    scopus 로고
    • Carboxyl methylation of the phosphoprotein phophatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo
    • Wu J, Tolstykh T, Lee J, Boyd K, Stock JB, and Broach JR. Carboxyl methylation of the phosphoprotein phophatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo. EMBO J 19: 5672-5681, 2000.
    • (2000) EMBO J , vol.19 , pp. 5672-5681
    • Wu, J.1    Tolstykh, T.2    Lee, J.3    Boyd, K.4    Stock, J.B.5    Broach, J.R.6
  • 45
    • 0027959477 scopus 로고
    • An enzymatic activity in bovine brain that catalyses the reversal of the C-terminal methyl esterification of protein phosphatase 2A
    • Xie H and Clarke S. An enzymatic activity in bovine brain that catalyses the reversal of the C-terminal methyl esterification of protein phosphatase 2A. Biochem Biophys Res Commun 203: 1710-1715, 1994.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 1710-1715
    • Xie, H.1    Clarke, S.2
  • 46
    • 0028154020 scopus 로고
    • Protein phosphatase 2A is reversibly modified by methyl esterification at its c-terminal leucine residue in bovine brain
    • Xie H and Clarke S. Protein phosphatase 2A is reversibly modified by methyl esterification at its c-terminal leucine residue in bovine brain. J Biol Chem 269: 1981-1984, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 1981-1984
    • Xie, H.1    Clarke, S.2
  • 47
    • 0141989958 scopus 로고    scopus 로고
    • New aspects of neurotransmitter release and exocytosis: Involvement of Ca(2+)/calmodulin-dependent phosphorylation of synapsin I in insulin exocytosis
    • Yamamoto H, Matsumoto K, Araki E, and Miyamoto E. New aspects of neurotransmitter release and exocytosis: involvement of Ca(2+)/calmodulin-dependent phosphorylation of synapsin I in insulin exocytosis. J Pharmacol Sci 93: 30-34, 2003.
    • (2003) J Pharmacol Sci , vol.93 , pp. 30-34
    • Yamamoto, H.1    Matsumoto, K.2    Araki, E.3    Miyamoto, E.4


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