Expression of milk fat globule epidermal growth factor 8 in immature dendritic cells for engulfment of apoptotic cells

European Journal of Immunology

Volumn 34, Issue 5, 2004, Pages 1414-1422

  Miyasaka, Kay ^a   Hanayama, Rikinari ^b   Tanaka, Masato ^b,c   Nagata, Shigekazu ^a,b,d  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c RIKEN   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Apoptosis; Dentritic cells; Engulfment; Langerhans cells; MFG E8

Indexed keywords

COLONY STIMULATING FACTOR 1; EPIDERMAL GROWTH FACTOR 8; EPIDERMAL GROWTH FACTOR DERIVATIVE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LIPOPOLYSACCHARIDE; MILK FAT; UNCLASSIFIED DRUG; EPIDERMAL GROWTH FACTOR; GLYCOLIPID; GLYCOPROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CULTURE; CELL MATURATION; CONTROLLED STUDY; CORRELATION FUNCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LANGERHANS CELL; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN SECRETION; SKIN CELL; STEM CELL; ANIMAL; METABOLISM; MILK FAT GLOBULE; PHYSIOLOGY; SECRETION;

ANIMALS; APOPTOSIS; DENDRITIC CELLS; EPIDERMAL GROWTH FACTOR; GLYCOLIPIDS; GLYCOPROTEINS; LANGERHANS CELLS; MICE; PHAGOCYTOSIS;

EID: 2442637158     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200424930     Document Type: Article

References (42)

1. Banchereau, J. and Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998. 392: 245-252.
2. Shortman, K. and Liu, Y. J., Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2002. 2: 151-161.
3. Ardavin, C., Origin, precursors and differentiation of mouse dendritic cells. Nat. Rev. Immunol. 2003. 3: 582-590.
4. Inaba, K., Turley, S., Yamaide, F., Iyoda, T., Mahnke, K., Inaba, M., Pack, M., Subklewe, M., Sauter, B., Sheff, D., Albert, M., Bhardwaj, N., Mellman, I. and Steinman, R. M., Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. J. Exp. Med. 1998. 188: 2163-2173.
5. Winzler, C., Rovere, P., Rescigno, M., Granucci, F., Penna, G., Adorini, L., Zimmermann, V. S., Davoust, J. and Ricciardi- Castagnoli, P., Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J. Exp. Med. 1997. 185: 317-328.
6. Rubartelli, A., Poggi, A. and Zocchi, M. R., The selective engulfment of apoptotic bodies by dendritic cells is mediated by the alpha(v)beta3 integrin and requires intracellular and extracellular calcium. Eur. J. Immunol. 1997. 27: 1893-1900.
7. Savill, J., Dransfield, I., Gregory, C. and Haslett, C., A blast from the past: clearance of apoptotic cells regulates immune responses. Nat. Rev. Immunol. 2002. 2: 965-975.
8. Savill, J. and Fadok, V., Corpse clearance defines the meaning of cell death. Nature 2000. 407: 784-788.
9. Fadok, V. A., Bratton, D. L., Frasch, S. C., Warner, M. L. and Henson, P. M., The role of phosphatidylserine in recognition of apoptotic cells by phagocytes. Cell Death Differ. 1998. 5: 551-562.
10. Fadok, V. A., Voelker, D. R., Campbell, P. A., Cohen, J. J., Bratton, D. L. and Henson, P. M., Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 1992. 148: 2207-2216.
11. Stubbs, J. D., Lekutis, C., Singer, K. L., Bui, A., Yuzuki, D., Srinivasan, U. and Parry, G., cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences. Proc. Natl. Acad. Sci. USA 1990. 87: 8417-8421.
12. Aoki, N., Kishi, M., Taniguchi, Y., Adachi, T., Nakamura, R. and Matsuda, T., Molecular cloning of glycoprotein antigens MGP57/53 recognized by monoclonal antibodies raised against bovine milk fat globule membrane. Biochim. Biophys. Acta 1995. 1245: 385-391.
13. Kanai, Y., Kanai-Azuma, M., Tajima, Y., Birk, O. S., Hayashi, Y. and Sanai, Y., Identification of a stromal cell type characterized by the secretion of a soluble integrin-binding protein, MFG-E8, in mouse early gonadogenesis. Mech. Dev. 2000. 96: 223-227.
14. Hanayama, R., Tanaka, M., Miwa, K., Shinohara, A., Iwamatsu, A. and Nagata, S., Identification of a factor that links apoptotic cells to phagocytes. Nature 2002. 417: 182-187.
15. Oshima, K., Aoki, N., Negi, M., Kishi, M., Kitajima, K. and Matsuda, T., Lactation-dependent expression of an mRNA splice variant with an exon for a multiply O-glycosylated domain of mouse milk fat globule glycoprotein MFG-E8. Biochem. Biophys. Res. Commun. 1999. 254: 522-528.
16. Gao, Y. S., Alvarez, C., Nelson, D. S. and Sztul, E., Molecular cloning, characterization, and dynamics of rat formiminotransferase cyclodeaminase, a Golgi-associated 58-kDa protein. J. Biol. Chem. 1998. 273: 33825-33834.
17. Albert, M. L., Sauter, B. and Bhardwaj, N., Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 1998. 392: 86-89.
18. Rescigno, M. and Borrow, P., The host-pathogen interaction: new themes from dendritic cell biology. Cell 2001. 106: 267-270.
19. Moser, M., Dendritic cells in immunity and tolerance - do they display opposite functions? Immunity 2003. 19: 5-8.
20. Urban, B. C., Willcox, N. and Roberts, D. J., A role for CD36 in the regulation of dendritic cell function. Proc. Natl. Acad. Sci. USA 2001. 98: 8750-8755.
21. Grolleau, A., Misek, D. E., Kuick, R., Hanash, S. and Mule, J. J., Inducible expression of macrophage receptor Marco by dendritic cells following phagocytic uptake of dead cells uncovered by oligonucleotide arrays. J. Immunol. 2003. 171: 2879-2888.
22. Fadok, V. A., Bratton, D. L., Rose, D. M., Pearson, A., Ezekewitz, R. A. and Henson, P. M., A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 2000. 405: 85-90.
23. Behrens, E. M., Gadue, P., Gong, S. Y., Garrett, S., Stein, P. L. and Cohen, P. L., The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity. Eur. J. Immunol. 2003. 33: 2160-2167.
24. Albert, M. L., Kim, J. I. and Birge, R. B., αvβ5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nat. Cell Biol. 2000. 2: 899-905.
25. Thery, C., Zitvogel, L. and Amigorena, S., Exosomes: composition, biogenesis and function. Nat. Rev. Immunol. 2002. 2: 569-579.
26. Denzer, K., Kleijmeer, M. J., Heijnen, H. F., Stoorvogel, W. and Geuze, H. J., Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. J. Cell Sci. 2000. 113: 3365-3374.
27. Oshima, K., Aoki, N., Kato, T., Kitajima, K. and Matsuda, T., Secretion of a peripheral membrane protein, MFG-E8, as a complex with membrane vesicles. Eur. J. Biochem. 2002. 269: 1209-1218.
28. Thery, C., Regnault, A., Garin, J., Wolfers, J., Zitvogel, L., Ricciardi-Castagnoli, P., Raposo, G. and Amigorena, S., Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. J. Cell. Biol. 1999. 147: 599-610.
29. Thery, C., Boussac, M., Veron, P., Ricciardi-Castagnoli, P., Raposo, G., Garin, J. and Amigorena, S., Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. J. Immunol. 2001. 166: 7309-7318.
30. Pan, B. T. and Johnstone, R. M., Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Cell 1983. 33: 967-978.
31. Zitvogel, L., Regnault, A., Lozier, A., Wolfers, J., Flament, C., Tenza, D., Ricciardi-Castagnoli, P., Raposo, G. and Amigorena, S., Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nat. Med. 1998. 4: 594-600.
32. Wu, L., D'Amico, A., Hochrein, H., O'Keeffe, M., Shortman, K. and Lucas, K., Development of thymic and splenic dendritic cell populations from different hemopoietic precursors. Blood 2001. 98: 3376-3382.
33. Manz, M. G., Traver, D., Miyamoto, T., Weissman, I. L. and Akashi, K., Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood 2001. 97: 3333-3341.
34. Geissmann, F., Jung, S. and Littman, D. R., Blood monocytes consist of two different principal subsets with distinct migratory properties. Immunity 2003. 19: 71-82.
35. Huang, F. P., Platt, N., Wykes, M., Major, J. R., Powell, T. J., Jenkins, C. D. and MacPherson, G. G., A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med. 2000. 191: 435-444.
36. Morelli, A. E., Larregina, A. T., Shufesky, W. J., Zahorchak, A. F., Logar, A. J., Papworth, G. D., Wang, Z., Watkins, S. C., Falo, L. D., Jr. and Thomson, A. W., Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production. Blood 2003. 101: 611-620.
37. Parr, M. B., Kepple, L. and Parr, E. L., Langerhans cells phagocytose vaginal epithelial cells undergoing apoptosis during the murine estrous cycle. Biol. Reprod. 1991. 45: 252-260.
38. Miyatake, S., Otsuka, T., Yokota, T., Lee, F. and Arai, K., Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes. EMBO J. 1985. 4: 2561-2568.
39. Takeshita, S., Kaji, K. and Kudo, A., Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts. J. Bone Miner. Res. 2000. 15: 1477-1488.
40. Inaba, K., Inaba, M., Romani, N., Aya, H., Deguchi, M., Ikehara, S., Muramatsu, S. and Steinman, R. M., Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 1992. 176: 1693-1702.
41. Bernateck, M., Jonas, L. and Diezel, W., Histochemical, immunohistochemical and ultrastructural studies on the action of glucocorticoids on epidermal Langerhans cells (ELC) of murine skin. Acta Histochem. 1996. 98: 101-106.
42. Kawane, K., Fukuyama, H., Yoshida, H., Nagase, H., Ohsawa, Y., Uchiyama, Y., Iida, T., Okada, K. and Negate, S., Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation. Nat. Immunol. 2003. 4: 138-144.