-
1
-
-
0025863072
-
Animal pharmacokinetics of selected imidazopyrimidine ligands for benzodiazepine receptors
-
Ager I.R., Doyle A.B., Hairsine P.W., McDonald K.P., Miller P., Parker F.L. Animal pharmacokinetics of selected imidazopyrimidine ligands for benzodiazepine receptors. Drug Dev. Res. 22:1991;349-361.
-
(1991)
Drug Dev. Res.
, vol.22
, pp. 349-361
-
-
Ager, I.R.1
Doyle, A.B.2
Hairsine, P.W.3
McDonald, K.P.4
Miller, P.5
Parker, F.L.6
-
2
-
-
0011760710
-
Studies of the efficacy of low affinity benzodiazepine receptor ligand on rat cerebellar activity
-
abstract
-
Bagust, J., Gardner, C.R., Walker, R.J., Ward, R.A., 1990. Studies of the efficacy of low affinity benzodiazepine receptor ligand on rat cerebellar activity. Br. J. Pharmacol., Suppl. 99, 251 (abstract).
-
(1990)
Br. J. Pharmacol.
, Issue.SUPPL. 99
, pp. 251
-
-
Bagust, J.1
Gardner, C.R.2
Walker, R.J.3
Ward, R.A.4
-
3
-
-
0029038196
-
GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain
-
Bockstaele E.V.J., Pickel V.M. GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain. Brain Res. 682:1995;215-221.
-
(1995)
Brain Res.
, vol.682
, pp. 215-221
-
-
Bockstaele, E.V.J.1
Pickel, V.M.2
-
4
-
-
4244152258
-
Effects of the selective, high affinity ligand ZG-63 for diazepam insensitive subtype of the benzodiazepine receptor on ethanol-reinforced responding
-
Abstract
-
Cason C.R., June H.L., Matecka D., Murphy J.M. Effects of the selective, high affinity ligand ZG-63 for diazepam insensitive subtype of the benzodiazepine receptor on ethanol-reinforced responding. Alcohol. Clin. Exp. Res. 20(12A):1996;51. (Abstract).
-
(1996)
Alcohol. Clin. Exp. Res.
, vol.20
, Issue.12 A
, pp. 51
-
-
Cason, C.R.1
June, H.L.2
Matecka, D.3
Murphy, J.M.4
-
5
-
-
0023937044
-
(Imidazo[1, 2-a]pyrimidin-2yl) phenylmethanones and related compounds as potential non-sedative anxiolytics
-
Clements-Jewery, Danswan S.G., Gardner C.R., Matharu S.S., Murdoch R., Tully W.R. (Imidazo[1, 2-a]pyrimidin-2yl) phenylmethanones and related compounds as potential non-sedative anxiolytics. J. Med. Chem. 31:1987;1220-1226.
-
(1987)
J. Med. Chem.
, vol.31
, pp. 1220-1226
-
-
Clements-Jewery1
Danswan, S.G.2
Gardner, C.R.3
Matharu, S.S.4
Murdoch, R.5
Tully, W.R.6
-
6
-
-
0028126555
-
Ethanol self-infusion into the ventral tegmental area by alcohol-preferring (P) rats
-
Gatto G.J., McBride W.J., Murphy J.M., Lumeng L., Li T.-K. Ethanol self-infusion into the ventral tegmental area by alcohol-preferring (P) rats. Alcohol. 11:1995;557-563.
-
(1995)
Alcohol
, vol.11
, pp. 557-563
-
-
Gatto, G.J.1
McBride, W.J.2
Murphy, J.M.3
Lumeng, L.4
Li, T.-K.5
-
7
-
-
0023779732
-
Functional in vivo correlates of the benzodiazepine agonist-inverse agonist continuum
-
Gardner C.R. Functional in vivo correlates of the benzodiazepine agonist-inverse agonist continuum. Prog. Neurobiol. 31:1988;425-476.
-
(1988)
Prog. Neurobiol.
, vol.31
, pp. 425-476
-
-
Gardner, C.R.1
-
8
-
-
0026722002
-
A review of recently-developed ligands for neuronal benzodiazepine receptors and their pharmacological activities
-
Gardner C.R. A review of recently-developed ligands for neuronal benzodiazepine receptors and their pharmacological activities. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 16:1992;755-781.
-
(1992)
Prog. Neuro-Psychopharmacol. Biol. Psychiatry
, vol.16
, pp. 755-781
-
-
Gardner, C.R.1
-
9
-
-
0023588057
-
Agonist and antagonist activities at benzodiazepine receptors of novel series of quinoline derivatives
-
Gardner C.R., Deacon R., James V., Parker F., Budhram P. Agonist and antagonist activities at benzodiazepine receptors of novel series of quinoline derivatives. Eur. J. Pharmacol. 142:1987;285-295.
-
(1987)
Eur. J. Pharmacol.
, vol.142
, pp. 285-295
-
-
Gardner, C.R.1
Deacon, R.2
James, V.3
Parker, F.4
Budhram, P.5
-
10
-
-
0025904324
-
Relationship between structure and efficacy at central benzodiazepine receptors for a series of imidazopyrimidines and imidazoquinolines
-
Gardner C.R., Budhram P., Deacon R.M., Thomson T.A. Relationship between structure and efficacy at central benzodiazepine receptors for a series of imidazopyrimidines and imidazoquinolines. Drug Dev. Res. 22:1991;309-320.
-
(1991)
Drug Dev. Res.
, vol.22
, pp. 309-320
-
-
Gardner, C.R.1
Budhram, P.2
Deacon, R.M.3
Thomson, T.A.4
-
12
-
-
0344205291
-
New quinoline derivatives as non-benzodiazepine anxiolytics
-
Uppsala
-
Hunt, P.F., Humbert, D., Gasc, J.C., Clemence, F., Boaventura, A.M., 1984. New quinoline derivatives as non-benzodiazepine anxiolytics. Proc. VIIIth Int. Symp. Med. Chem., Uppsala, pp. 290-292.
-
(1984)
Proc. VIIIth Int. Symp. Med. Chem.
, pp. 290-292
-
-
Hunt, P.F.1
Humbert, D.2
Gasc, J.C.3
Clemence, F.4
Boaventura, A.M.5
-
14
-
-
0028981524
-
A receptor antagonism in the extended amygdala decreases ethanol self-administration in rats
-
A receptor antagonism in the extended amygdala decreases ethanol self-administration in rats. Eur. J. Pharmacol. 283:1995;151-159.
-
(1995)
Eur. J. Pharmacol.
, vol.283
, pp. 151-159
-
-
Hyytiä, P.1
Koob, G.F.2
-
15
-
-
0028360721
-
Ethanol self-administration in freely feeding rats: Effects of RO15-4513 alone and in combination with flumazenil (RO15-1788)
-
June H.L., Hughes R.W., Spurlock H.L., Lewis M.J. Ethanol self-administration in freely feeding rats: effects of RO15-4513 alone and in combination with flumazenil (RO15-1788). Psychopharmacology (Berlin). 115:1994;332-339.
-
(1994)
Psychopharmacology (Berlin)
, vol.115
, pp. 332-339
-
-
June, H.L.1
Hughes, R.W.2
Spurlock, H.L.3
Lewis, M.J.4
-
16
-
-
0001324144
-
RO19-4603 exerts prolonged and selective suppression of ethanol intake in the alcohol-preferring (P) rats
-
June H.L., Murphy J.M., Mellor-Burke J., Lumeng L., Li T.-K. RO19-4603 exerts prolonged and selective suppression of ethanol intake in the alcohol-preferring (P) rats. Psychopharmacol. (Berlin). 115:1994;332-339.
-
(1994)
Psychopharmacol. (Berlin)
, vol.115
, pp. 332-339
-
-
June, H.L.1
Murphy, J.M.2
Mellor-Burke, J.3
Lumeng, L.4
Li, T.-K.5
-
17
-
-
0029102245
-
Effects of negative modulators of GABAergic efficacy on ethanol intake: Correlation of biochemical changes with pharmacological effect using a behavioral paradigm
-
June H.L., Lin M., Greene T.L., Lewis M.J., Murphy J.M. Effects of negative modulators of GABAergic efficacy on ethanol intake: correlation of biochemical changes with pharmacological effect using a behavioral paradigm. J. Exp. Clin. Psychopharmacol. 3:1995;252-260.
-
(1995)
J. Exp. Clin. Psychopharmacol.
, vol.3
, pp. 252-260
-
-
June, H.L.1
Lin, M.2
Greene, T.L.3
Lewis, M.J.4
Murphy, J.M.5
-
18
-
-
0030023609
-
Benzodiazepine receptor ligands with different intrinsic efficacies alter ethanol intake in alcohol-nonpreferring (NP) rats
-
June H.L., Murphy J.M., Hewitt R.L., Greene T.L., Hite M.L., Mellor-Burke J., Lumeng L., Li T.-K. Benzodiazepine receptor ligands with different intrinsic efficacies alter ethanol intake in alcohol-nonpreferring (NP) rats. Neuropsychopharmacology. 14:1996;55-66.
-
(1996)
Neuropsychopharmacology.
, vol.14
, pp. 55-66
-
-
June, H.L.1
Murphy, J.M.2
Hewitt, R.L.3
Greene, T.L.4
Hite, M.L.5
Mellor-Burke, J.6
Lumeng, L.7
Li, T.-K.8
-
19
-
-
0030599140
-
Effects of the benzodiazepine inverse agonist RO19-4603 alone and in combination with the benzodiazepine receptor antagonists flumazenil, ZK 93426, and CGS 8216, on ethanol intake in alcohol-preferring (P) rats
-
June H.L., Green T.L., Murphy J.M., Hite M.L., Williams J.A., Cason C.R., Mellor-Burke J., Cox R., Duemler S.E., Torres L., Lumeng L., Li T.-K. Effects of the benzodiazepine inverse agonist RO19-4603 alone and in combination with the benzodiazepine receptor antagonists flumazenil, ZK 93426, and CGS 8216, on ethanol intake in alcohol-preferring (P) rats. Brain Res. 734:1996;19-34.
-
(1996)
Brain Res.
, vol.734
, pp. 19-34
-
-
June, H.L.1
Green, T.L.2
Murphy, J.M.3
Hite, M.L.4
Williams, J.A.5
Cason, C.R.6
Mellor-Burke, J.7
Cox, R.8
Duemler, S.E.9
Torres, L.10
Lumeng, L.11
Li, T.-K.12
-
20
-
-
0010572186
-
GABAergic transmission in the mesoaccumbens is involved in alcohol reinforcement
-
Paper presented at the 6th Congress of the European Society for Biomedical Research on Alcoholism, in the Symposium entitled, Neurobiology of Alcohol Reinforcement, Stockholm, Sweden. (Abstract # SY115)
-
June, H.L., Hwang, B.W., Murphy, J.M., 1997. GABAergic transmission in the mesoaccumbens is involved in alcohol reinforcement. Paper presented at the 6th Congress of the European Society for Biomedical Research on Alcoholism, in the Symposium entitled, Neurobiology of Alcohol Reinforcement, Stockholm, Sweden. Alcohol and Alcoholism. 32, 337 (Abstract # SY115).
-
(1997)
Alcohol and Alcoholism
, vol.32
, pp. 337
-
-
June, H.L.1
Hwang, B.W.2
Murphy, J.M.3
-
21
-
-
0032536399
-
The novel benzodiazepine inverse agonist RO19-4603 antagonizes ethanol motivated behaviors: Neuropharmacological studies
-
June H.L., Torres L., Cason C.R., Braun M.R., Hwang B.W., Murphy J.M. The novel benzodiazepine inverse agonist RO19-4603 antagonizes ethanol motivated behaviors: neuropharmacological studies. Brain Res. 784:1998;256-275.
-
(1998)
Brain Res.
, vol.784
, pp. 256-275
-
-
June, H.L.1
Torres, L.2
Cason, C.R.3
Braun, M.R.4
Hwang, B.W.5
Murphy, J.M.6
-
22
-
-
0031888652
-
High affinity benzodiazepine antagonists reduce responding maintained by ethanol presentation in ethanol-preferring rats
-
June H.L., Zuccarelli D., Torres L., Cason C.R., Murphy J.M. High affinity benzodiazepine antagonists reduce responding maintained by ethanol presentation in ethanol-preferring rats. J. Pharmacol. Exp. Ther. 284:1998;1006-1014.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.284
, pp. 1006-1014
-
-
June, H.L.1
Zuccarelli, D.2
Torres, L.3
Cason, C.R.4
Murphy, J.M.5
-
23
-
-
0032567801
-
A-benzodiazepine receptor antagonists CGS 8216, and ZK 93426 modulate the behavioral actions of ethanol in alcohol-preferring (P) and nonpreferring (NP) rats
-
A-benzodiazepine receptor antagonists CGS 8216, and ZK 93426 modulate the behavioral actions of ethanol in alcohol-preferring (P) and nonpreferring (NP) rats. Eur. J. Pharmacol. 342:1998;139-151.
-
(1998)
Eur. J. Pharmacol.
, vol.342
, pp. 139-151
-
-
June, H.L.1
Devaraju, S.L.2
Eggers, M.W.3
Williams, J.A.4
Cason, C.R.5
Greene, T.L.6
Leveige, T.7
Braun, M.R.8
Torres, L.9
Murphy, J.M.10
-
24
-
-
0026759536
-
Neural mechanism of drug reinforcement
-
Kalivas, P.W., Samson, H.H. (Eds.), Neurobiology of Drug and Alcohol Addiction
-
Koob, G.F., 1992. Neural mechanism of drug reinforcement. In: Kalivas, P.W., Samson, H.H. (Eds.), Neurobiology of Drug and Alcohol Addiction. Ann. NY Acad. Sci. 654, 171-192.
-
(1992)
Ann. NY Acad. Sci.
, vol.654
, pp. 171-192
-
-
Koob, G.F.1
-
25
-
-
0026507628
-
Drug abuse: Anatomy, pharmacology and function of reward pathways
-
Koob G.F. Drug abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol. Sci. 13:1992;177-184.
-
(1992)
Trends Pharmacol. Sci.
, vol.13
, pp. 177-184
-
-
Koob, G.F.1
-
26
-
-
0023763088
-
Cellular and molecular mechanism of drug dependence
-
Koob G.F., Bloom F.E. Cellular and molecular mechanism of drug dependence. Science. 242:1988;715-723.
-
(1988)
Science
, vol.242
, pp. 715-723
-
-
Koob, G.F.1
Bloom, F.E.2
-
28
-
-
0345499011
-
Antagonism of the anxiolytic activity of diazepam by a new quinoline carboxamide compound Ru 40410
-
Florence (Abstract)
-
Laurent, J., 1984. Antagonism of the anxiolytic activity of diazepam by a new quinoline carboxamide compound Ru 40410. Proc. 13th CINP Congress, Florence (Abstract).
-
(1984)
Proc. 13th CINP Congress
-
-
Laurent, J.1
-
29
-
-
0001471990
-
Molecular and genetic approaches to understanding alcohol-seeking behavior
-
Meyer, R.E., Koob, G.F., Lewis, M.J., Paul, S.L. (Eds.). Birhauser, Boston
-
Li, T.-K., D.W. Crabb, L. Lumeng, 1991. Molecular and genetic approaches to understanding alcohol-seeking behavior. In: Meyer, R.E., Koob, G.F., Lewis, M.J., Paul, S.L. (Eds.), Neuropharmacology of Ethanol. Birhauser, Boston, pp. 107-124.
-
(1991)
Neuropharmacology of Ethanol
, pp. 107-124
-
-
Li, T.-K.1
Crabb, D.W.2
Lumeng, L.3
-
30
-
-
0020064180
-
Different sensitivities to ethanol in alcohol-preferring (P) and nonpreferring (NP) rats. Genetic influences on alcohol preference in animals
-
Lumeng L., Waller M.B., McBride W.J., Li T.-K. Different sensitivities to ethanol in alcohol-preferring (P) and nonpreferring (NP) rats. Genetic influences on alcohol preference in animals. Pharmacol. Biochem. Behav. 16:1982;125-130.
-
(1982)
Pharmacol. Biochem. Behav.
, vol.16
, pp. 125-130
-
-
Lumeng, L.1
Waller, M.B.2
McBride, W.J.3
Li, T.-K.4
-
31
-
-
0001046495
-
Genetic influences on alcohol preference in animals
-
Begleiter, H., Kissin, B. (Eds.), Oxford Univ. Press, New York
-
Lumeng, L., Murphy, J.M., McBride, W.J., Li, T.-K., 1995. Genetic influences on alcohol preference in animals. In: Begleiter, H., Kissin, B. (Eds.), The Genetics of Alcoholism, Oxford Univ. Press, New York, pp. 161-173.
-
(1995)
The Genetics of Alcoholism
, pp. 161-173
-
-
Lumeng, L.1
Murphy, J.M.2
McBride, W.J.3
Li, T.-K.4
-
32
-
-
0003717437
-
-
Academic Press, Orlando, FL
-
Paxinos, G., Watson, C., 1986. The Rat Brain in Stereotaxic Coordinates. Academic Press, Orlando, FL.
-
(1986)
The Rat Brain in Stereotaxic Coordinates
-
-
Paxinos, G.1
Watson, C.2
-
33
-
-
0022497706
-
Initiation of ethanol reinforcement using a sucrose-substitution procedure in food-and-water-sated rats
-
Samson H.H. Initiation of ethanol reinforcement using a sucrose-substitution procedure in food-and-water-sated rats. Alcohol. Clin. Exp. Res. 10:1986;436-442.
-
(1986)
Alcohol. Clin. Exp. Res.
, vol.10
, pp. 436-442
-
-
Samson, H.H.1
-
34
-
-
0001353578
-
Initiation of ethanol maintained behavior: A comparison of animal models and their implication to human drinking
-
Samson H.H. Initiation of ethanol maintained behavior: a comparison of animal models and their implication to human drinking. Adv. Behav. Pharmacol. 6:1987;221-248.
-
(1987)
Adv. Behav. Pharmacol.
, vol.6
, pp. 221-248
-
-
Samson, H.H.1
-
35
-
-
0023042881
-
A selective imidazobenzodiazepine antagonist of ethanol in the rat
-
Sudzak P.D., Glowa J.R., Crawley J.N., Schwartz R.D., Skolnick P., Paul S.M. A selective imidazobenzodiazepine antagonist of ethanol in the rat. Science. 243:1986;1243-1247.
-
(1986)
Science
, vol.243
, pp. 1243-1247
-
-
Sudzak, P.D.1
Glowa, J.R.2
Crawley, J.N.3
Schwartz, R.D.4
Skolnick, P.5
Paul, S.M.6
-
36
-
-
0001486897
-
Neuropharmacology of ethanol
-
Meyer, R.E., Koob, G.F., Lewis, M.J., Paul, S.L. (Eds.). Birkhauser, Boston
-
Weiss, F., Koob, G.F., 1991. Neuropharmacology of ethanol. In: Meyer, R.E., Koob, G.F., Lewis, M.J., Paul, S.L. (Eds.), Neuropharmacology of Ethanol. Birkhauser, Boston, pp. 125-162.
-
(1991)
Neuropharmacology of Ethanol
, pp. 125-162
-
-
Weiss, F.1
Koob, G.F.2
-
37
-
-
0026585373
-
High affinity ligands for diazepam-insensitive benzodiazepine receptors
-
Wong G., Skolnick P. High affinity ligands for diazepam-insensitive benzodiazepine receptors. Eur. J. Pharmacol. 225:1992;63-68.
-
(1992)
Eur. J. Pharmacol.
, vol.225
, pp. 63-68
-
-
Wong, G.1
Skolnick, P.2
-
39
-
-
0028912677
-
Development of a comprehensive pharmacophore model for the benzodiazepine receptor
-
Zhang W., Koehler K.F., Zhang P., Cook J.M. Development of a comprehensive pharmacophore model for the benzodiazepine receptor. Drug Des. Discov. 12:1995;193-248.
-
(1995)
Drug Des. Discov.
, vol.12
, pp. 193-248
-
-
Zhang, W.1
Koehler, K.F.2
Zhang, P.3
Cook, J.M.4
|