The Drosophila Polycomb group gene Sex combs extra encodes the ortholog of mammalian Ring1 proteins

Mechanisms of Development

Volumn 121, Issue 5, 2004, Pages 449-462

  Gorfinkiel, Nicole ^a   Fanti, Laura ^b   Melgar, Teresa ^c   García, Emiliano ^c   Pimpinelli, Sergio ^b   Guerrero, Isabel ^a   Vidal, Miguel ^c  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Drosophila Ring; Polycomb group; Ring1A; Ring1B; Sex combs extra

Indexed keywords

ARTICLE; CHROMOSOME; DROSOPHILA; GENE EXPRESSION; GENE REPRESSION; GENETIC CONSERVATION; HOMEOBOX; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; ANTENNAPEDIA HOMEODOMAIN PROTEIN; CHROMOSOMES; CLONING, MOLECULAR; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; EXPRESSED SEQUENCE TAGS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; IN SITU HYBRIDIZATION; LARVA; MAMMALS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PHENOTYPE; PHYSICAL CHROMOSOME MAPPING; PROTEIN BINDING; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TRANSCRIPTION FACTORS;

MAMMALIA; MURINAE;

EID: 2442564417     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mod.2004.03.019     Document Type: Article

References (70)

1. Bel S., Core N., Djabali M., Kieboom K., Van der Lugt N., Alkema M.J., Van Lohuizen M. Genetic interactions and dosage effects of Polycomb group genes in mice. Development. 125:1998;3543-3551
2. Beuchle D., Struhl G., Muller J. Polycomb group proteins and heritable silencing of Drosophila Hox genes. Development. 128:(6):2001;993-1004
3. Brand A.H., Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118:1993;401-415
4. Breen T.R., Duncan I.M. Maternal expression of genes that regulate the bithorax complex of developmental biology. Dev. Biol. 118:1986;442-456
5. Brown J.L., Mucci D., Whiteley M., Dirksen M.L., Kassis J.A. The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1. Mol. Cell. 1:1998;1057-1064
6. Busturia A., Bienz M. Silencers in abdominal-B, a homeotic Drosophila gene. Eur. Mol. Biol. Org. J. 12:1993;1415-1425
7. Busturia A., Morata G. Ectopic expression of homeotic genes caused by the elimination of the Polycomb gene in Drosophila imaginal epidermis. Development. 104:1988;713-720
8. Casso D., Ramirez-Weber F., Kornberg T.B. GFP-tagged balancer chromosomes for Drosophila melanogaster. Mech. Dev. 91:2000;451-454
9. Cheng N.S.N., Sinclair D.A.R., Campbell R.B., Brock H.W. Interactions of polyhomeotic with Polycomb group genes of Drosophila melanogaster. Genetics. 138:1994;1151-1162
10. Chiang A., Oconnor M.B., Paro R., Simon J., Bender W. Discrete Polycomb-binding sites in each parasegmental domain of the bithorax complex. Development. 121:1995;1681-1689
11. Czermin B., Melfi R., McCabe D., Seitz V., Imhof A., Pirrotta V. Drosophila Enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell. 111:2002;185-196
12. DeCamillis M., Cheng N.S., Pierre D., Brock H.W. The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb. Genes Dev. 6:1992;223-232
13. Francis N.J., Saurin A.J., Shao Z., Kingston R.E. Reconstitution of a functional core Polycomb repressive complex. Mol. Cell. 8:2001;545-556
14. Franke A., DeCamillis M., Zink D., Cheng N., Brock H.W., Paro R. Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster. Eur. Mol. Biol. Org. J. 11:1992;2941-2950
15. Fritsch C., Brown J.L., Kassis J.A., Muller J. The DNA-binding Polycomb group protein pleiohomeotic mediates silencing of a Drosophila homeotic gene. Development. 126:1999;3905-3913
16. Fritsch C., Beuchle D., Muller J. Molecular and genetic analysis of the Polycomb group gene Sex combs extra/Ring in Drosophila. Mech. Dev. 120:2003;949-954
17. Garcia E., Marcos-Gutierrez C., del Mar Lorente M., Moreno J.C., Vidal M. RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1. Eur. Mol. Biol. Org. J. 18:1999;3404-3418
18. Gindhart J.G., Kaufman T.C. Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced. Genetics. 139:1995;797-814
19. Gould A. Functions of mammalian Polycomb group and trithorax group related genes. Curr. Opin. Genet. Dev. 7:1997;488-494
20. Hashimoto N., Brock H.W., Nomura M., Kyba M., Hodgson J., Fujita Y., et al. RAE28, BMI1, and M33 are members of heterogeneous multimeric mammalian Polycomb group complexes. Biochem. Biophys. Res. Commun. 245:1998;356-365
21. Hemenway C.S., Halligan B.W., Levy L.S. The Bmi-1 oncoprotein interacts with dinG and MPh2: the role of RING finger domains. Oncogene. 16:1998;2541-2547
22. Hur M.W., Laney J.D., Jeon S.H., Ali J., Biggin M.D. Zeste maintains repression of Ubx transgenes: support for a new model of Polycomb repression. Development. 129:2002;1339-1343
23. James T.C., Eissenberg J.C., Craig C., Dietrich V., Hobson A., Elgin S.C.R. Distribution patterns of HP1, a heterochromatin-associated non-histone chromosomal protein of Drosophila. Eur. J. Cell. Biol. 50:1989;170-180
24. Jürgens G. A group of genes controlling the spatial expression of the bithorax complex in Drosophila. Nature. 316:1985;153-155
25. Kennison J.A. The Polycomb and trithorax group proteins of Drosophila: trans-regulators of homeotic gene function. Annu. Rev. Genet. 29:1995;289-303
26. Kyba M., Brock H.W. The SAM domain of polyhomeotic, RAE28, and scm mediates specific interactions through conserved residues. Dev. Genet. 22:1998;74-84
27. Kyba M., Brock H.W. The Drosophila Polycomb group protein Psc contacts ph and Pc through specific conserved domains. Mol. Cell. Biol. 18:1998;2712-2720
28. Levine S.S., Weiss A., Erdjument-Bromage H., Shao Z., Tempst P., Kingston R.E. The core of the Polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol. Cell. Biol. 22:2002;6070-6078
29. Lewis E.B. A gene complex controlling segmentation in Drosophila. Nature. 276:1978;565-570
30. Lonie A., D'Andrea R., Paro R., Saint R. Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression. Development. 120:1994;2629-2636
31. del Mar Lorente M., Marcos-Gutierrez C., Perez C., Schoorlemmer J., Ramirez A., Magin T., Vidal M. Loss- and gain-of-function mutations show a Polycomb group function for Ring1A in mice. Development. 127:2000;5093-5100
32. Martin E.C., Adler P.N. The Polycomb group gene Posterior Sex combs encodes a chromosomal protein. Development. 117:1993;641-655
33. Maurange C., Paro R. A cellular memory module conveys epigenetic inheritance of hedgehog expression during Drosophila wing imaginal disc development. Genes Dev. 16:2002;2672-2683
34. Moazed D., O'Farrell P.H. Maintenance of the engrailed expression pattern by Polycomb group genes in Drosophila. Development. 116:1992;805-810
35. Muller J., Gaunt S., Lawrence P.A. Function of the Polycomb protein is conserved in mice and flies. Development. 121:1995;2847-2852
36. Muller J., Hart C.M., Francis N.J., Vargas M.L., Sengupta A., Wild B., et al. Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell. 111:2002;197-208
37. Ng J., Hart C.M., Morgan K., Simon J.A. A Drosophila ESC-E(Z) protein complex is distinct from other Polycomb group complexes and contains covalently modified ESC. Mol. Cell. Biol. 20:2000;3069-3078
38. Ogawa H., Ishiguro K., Gaubatz S., Livingston D.M., Nakatani Y. A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. Science. 296:2002;1132-1136
39. Orlando V. Polycomb, epigenomes, and control of cell identity. Cell. 112:2003;599-606
40. Orlando V., Jane E.P., Chinwalla V., Harte P.J., Paro R. Binding of trithorax and Polycomb proteins to the bithorax complex: dynamic changes during early Drosophila embryogenesis. Eur. Mol. Biol. Org. J. 17:1998;5141-5150
41. Paro R., Hogness D.S. The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl Acad. Sci. USA. 88:1991;263-267
42. Pelegri F., Lehmann R. A role of Polycomb group genes in the regulation of gap gene expression in Drosophila. Genetics. 136:1994;1341-1353
43. Peterson A.J., Kyba M., Bornemann D., Morgan K., Brock H.W., Simon J. A domain shared by the Polycomb group proteins Scm and Ph mediates heterotypic and homotypic interactions. Mol. Cell. Biol. 17:1997;6683-6692
44. Pimpinelli S., Bonaccorsi S., Fanti L., Gatti M. Sullivan W., Ashburner M., Hawley S. Drosophila: A Laboratory Manual. 2000;1-24 Cold Spring Harbor Laboratory, Plainview, NY
45. Pirrotta V. Polycombing the genome: PcG, trxG, and chromatin silencing. Cell. 93:1998;333-336
46. Poux S., Melfi R., Pirrotta V. Establishment of Polycomb silencing requires a transient interaction between PC and ESC. Genes Dev. 15:2001;2509-2514
47. Preuss D. Chromatin silencing and Arabidopsis development: a role for Polycomb proteins. Plant Cell. 11:1999;765-768
48. Rastelli L., Chan C.S., Pirrotta V. Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function. Eur. Mol. Biol. Org. J. 12:1993;1513-1522
49. Ringrose L., Rehmsmeier M., Dura J.-M., Paro R. Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Mol. Cell. 5:2003;759-771
50. Satijn D.P., Otte A.P. RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activity. Mol. Cell. Biol. 19:1999;57-68
51. Satijn D.P., Gunster M.J., van der Vlag J., Hamer K.M., Schul W., Alkema M.J., et al. RING1 is associated with the Polycomb group protein complex and acts as a transcriptional repressor. Mol. Cell. Biol. 17:1997;4105-4113
52. Saurin A.J., Shao Z., Erdjument-Bromage H., Tempst P., Kingston R.E. A Drosophila Polycomb group complex includes Zeste and dTAFII proteins. Nature. 412:2001;655-660
53. Schoorlemmer J., Marcos-Gutierrez C., Were F., Martinez R., Garcia E., Satijn D.P., et al. Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain. Eur. Mol. Biol. Org. J. 16:1997;5930-5942
54. Schumacher A., Magnuson T. Murine Polycomb- and trithorax-group genes regulate homeotic pathways and beyond. Trends Genet. 13:1997;167-170
55. Shao Z., Raible F., Mollaaghababa R., Guyon J.R., Wu C.T., Bender W., Kingston R.E. Stabilization of chromatin structure by PRC1, a Polycomb complex. Cell. 98:1999;37-46
56. Shelton C.A., Wasserman S.A. Pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo. Cell. 72:1993;515-525
57. Shimell M.J., Peterson A.J., Burr J., Simon J.A., O'Connor M.B. Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene. Dev. Biol. 218:2000;38-52
58. Simon J., Chiang A., Bender W. Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products. Development. 114:1992;493-505
59. Simon J., Chiang A., Bender W., Shimell M.J., O'Connor M. Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products. Dev. Biol. 158:1993;131-144
60. Sinclair D., Milne T., Hodgson J., Shellard J., Salinas C., Kyba M., et al. The additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes. Development. 125:1998;1207-1216
61. Soto M.C., Chou T.B., Bender W. Comparison of germ-line mosaics of genes in the Polycomb group of Drosophila melanogaster. Genetics. 140:1995;231-243
62. Struhl K., Akam M.E. Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila. Eur. Mol. Biol. Org. J. 4:1985;3259-3264
63. Strutt H., Paro R. The Polycomb group protein complex of Drosophila melanogaster has different compositions at different target genes. Mol. Cell. Biol. 17:1997;6773-6783
64. Strutt H., Cavalli G., Paro R. Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression. Eur. Mol. Biol. Org. J. 16:1997;3621-3632
65. Suzuki M., Mizutani-Koseki Y., Fujimura Y.I., Miyagishima H., Kaneko T., Takada Y. Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice. Development. 129:2002;4171-4183
66. Tautz D., Pfeifle C. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma. 98:1989;81-85
67. Tillib S., Petruk S., Sedkov Y., Kuzin A., Fujioka M., Goto T., Mazo A. Trithorax- and Polycomb-group response elements within an Ultrabithorax transcription maintenance unit consist of closely situated but separable sequences. Mol. Cell. Biol. 19:1999;5189-5202
68. Wang J., Mager J., Schnedier E., Magnuson T. The mouse PcG gene eed is required for Hox gene repression and extraembryonic development. Mamm. Genome. 13:2002;493-503
69. Yoffe, K.B., Manoukian, A.S., Wilder, E.L., Brand, A.H., Perrimon, N., 1995. Evidence for engrailed-independent wingless autoregulation in Drosophila. Dev. Biol. 170, 636-650.
70. Zink B., Paro R. In vivo binding pattern of a trans-regulator of homeotic genes in Drosophila melanogaster. Nature. 337:1989;468-471