The Drosophila polycomb group protein Psc contacts ph and Pc through specific conserved domains

Molecular and Cellular Biology

Volumn 18, Issue 5, 1998, Pages 2712-2720

  Kyba, Michael ^a   Brock, Hugh W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COMPLEX FORMATION; DROSOPHILA MELANOGASTER; GENETIC CONSERVATION; HOMEOBOX; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

DROSOPHILA;

EID: 0031918895     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.5.2712     Document Type: Article

References (52)

1. Adler, P. N., J. Charlton, and B. Brunk. 1989. Genetic interactions of the Suppressor 2 of zeste region genes. Dev. Genet. 10:249-260.
2. Akasaka, T., M. Kanno, R. Balling, M. A. Mieza, M. Taniguchi, and H. Koseki. 1996. A role for mel-18, a Polycomh group-related vertebrate gene, during the anteroposterior specification of the axial skeleton. Development 122:1513-1522.
3. Alkema, M. J., M. Bronk, E. Verhoeven, A. Otte, L. J. van't Veer, A. Berns, and M. van Lohuizen. 1997. Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian Polycomb complex. Genes Dev. 11:226-240.
4. Alkema, M. J., N. M. T. van der Lugt, R. C. Bobeldijk, A. Berns, and M. van Lohuizen. 1995. Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice. Nature 374:724-727.
5. Bornemann, D., E. Miller, and J. Simon. 1996. The Drosophila Polycomb group gene Sex comb on midleg (Scm) encodes a zinc finger protein with similarity to polyhomeotic protein. Development 122:1621-1630.
6. Brunk, B. P., E. C. Martin, and P. N. Adler. 1991. Drosophila genes Posterior sex combs and Suppressor two of zeste encode proteins with homology to the murine bmi-1 oncogene. Nature 353:351-353.
7. Campbell, R. B., D. A. R. Sinclair, M. Couling, and H. W. Brock. 1995. Genetic interactions and dosage effects of Polycomb group genes of Drosophila. Mol. Gen. Genet. 246:291-300.
8. Carrington, E. A., and R. S. Jones. 1996. The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution. Development 122:4073-4083.
9. Cheng, N. N., D. A. R. Sinclair, R. B. Campbell, and H. W. Brock. 1994. Interactions of polyhomeotic with Polycomb group genes at Drosophila melanogaster. Genetics 138:1151-1162.
10. Coré, N., S. Bel, S. J. Gaunt, M. Aurrand-Lions, J. Pearce, A. Fisher, and M. Djabali. 1997. Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice. Development 124:721-729.
11. DeCamillis, M. A., N. Cheng, D. Pierre, and H. W. Brock. 1992. The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome binding sites with Polycomb. Genes Dev. 6:223-232.
12. Estojak, J., R. Brent, and E. A. Golemis. 1995. Correlation of two-hybrid affinity data with in vitro measurements. Mol. Cell. Biol. 15:5820-5829.
13. Franke, A., M. A. DeCamillis, D. Zink, N. Cheng, H. W. Brock, and R. Paro. 1992. Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster. EMBO J. 11:2941-2950.
14. Golemis, E. A., J. Gyuris, and R. Brent. 1993. Two hybrid systems/interaction traps, p. 13.14.1-13.14.17. In F. M. Ausubel, R. Brent, R. Kingston, D. Moore, J. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology. John Wiley & Sons, New York, N.Y.
15. Gunster, M. J., D. P. E. Satijn, K. M. Hamer, J. L. den Blaauwen, D. de Bruijn, M. J. Alkema, M. van Lohuizen, R. van Driel, and A. P. Otte. 1997. Identification and characterization of interactions between the vertebrate Polycomb-group protein BMI1 and human homologs of Polyhomeotic. Mol. Cell. Biol. 17:2326-2335.
16. Gyuris, J., E. Golemis, H. Chertkov, and R. Brent. 1993. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75:791-803.
17. Harding, K., and M. Levine. 1988. Gap genes define the limits of Antenna-pedia and bithorax gene expression during early development in Drosophila. EMBO J. 7:205-214.
18. Hashimoto, N., H. W. Brock, M. Nomura, M. Kyba, J. Hodgson, Y. Fujita, Y. Takihara, K. Shimada, and T. Higashinakagawa. Submitted for publication
19. Heberlein, U., B. England, and R. Tjian. 1985. Characterization of Drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene. Cell 41:965-977.
20. Hodgson, J. W., N. N. Cheng, D. A. R. Sinclair, M. Kyba, N. B. Randsholt, and H. W. Brock. 1997. The polyhomeotic locus of Drosophila melanogaster is transcriptionally and post-transcriptionally regulated during embryogenesis. Mech. Dev. 66:69-81.
21. Irminger-Finger, I., and R. Nothiger. 1995. The Drosophila melanogaster gene lethel(3)Ah encodes a ring finger protein homologous to the oncoproteins MEL-18 and BMI-1. Gene 163:203-208.
22. Jones, R. S., and W. M. Gelbart. 1990. Genetic analysis of the Enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster. Genetics 126:185-199.
23. Jurgens, G. 1985. A group of genes controlling the spatial expression of the bithorax complex in Drosophila. Nature 316:153-155.
24. Kaufman, T. C., R. A. Lewis, and B. T. Wakimoto. 1980. Cytogenetic analysis of chromosome 3 in Drosophila melanogaster: the homeotic gene complex in polytene chromosome interval 84A-B. Genetics 94:115-133.
25. Kennison, J. A., and M. A. Russell. 1987. Dosage-dependent modifiers of homeotic mutations in Drosophila melanogaster. Genetics 116:75-86.
26. Kyba, M., and H. Brock. 1998. The SAM domain of Polyhomeotic, RAE28, and Scm mediates specific interactions through conserved residues. Dev. Genet. 22:74-78.
27. Kyba, M. Unpublished data.
28. Lewis, E. B. 1978. A gene complex controlling segmentation in Drosophila. Nature 276:565-570.
29. Locke, J., M. A. Kotarski, and K. D. Tartof. 1988. Dosage-dependent modifiers of position-effect variegation in Drosophila and a mass action model that explains their effect. Genetics 120:181-198.
30. Lonie, A., R. D'Andrea, R. Paro, and R. Saint. 1994. Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression. Development 120:2629-2636.
31. Martin, E. C., and P. N. Adler. 1993. The Polycomb group gene Posterior sex combs encodes a chromosomal protein. Development 117:641-655.
32. McKeon, J., and H. W. Brock. 1991. Interactions of the Polycomb group of genes with homeotic loci of Drosophila. Arch. Dev. Biol. 199:387-396.
33. Muller, J., S. Gaunt, and P. A. Lawrence. 1995. Function of the Polycomb protein is conserved in mice and flies. Development 121:2847-2852.
34. Nomura, M., Y. Takihara, and K. Shimada. 1994. Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: one of the early inducible clones encodes a novel protein sharing several highly homologous regions with a Drosophila polyhomeotic protein. Differentiation 57:39-50.
35. Parker, C., and J. Topol. 1984. A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity. Cell 36:357-369.
36. Paro, R., and D. S. Hogness. 1991. The Polycomb protein shares a homologous domain with a heterochromatin-associated protein in Drosophila. Proc. Natl. Acad. Sci. USA 88:263-267.
37. Pearce, J. H. H., P. B. Singh, and S. J. Gaunt. 1992. The mouse has a Polycomb-like chromobox gene. Development 114:921-929.
38. Peterson, A., M. Kyba, D. Borneman, K. Morgan, H. Brock, and J. Simon. 1997. A domain shared by the Polycomb group proteins Scm and ph mediates heterotypic and homotypic interactions. Mol. Cell Biol. 17:6683-6692.
39. Phillips, M. D., and A. Shearn. 1990. Mutations in polycombeotic, a Drosophila Polycomb group gene, cause a wide range of maternal and zygotic phenotypes. Genetics 125:91-101.
40. Ponting, C. P. 1995. SAM: a novel motif in yeast sterile and Drosophila polyhomeotic proteins. Protein Sci. 4:1928-1930.
41. Rastelli, L., C. S. Chan, and V. Pirrotta. 1993. Related chromosome binding sites for zeste, suppressor of zeste and Polycomb group protein and their dependence on Enhancer of zeste function. EMBO J. 12:1513-1522.
42. Reijnen M. J., K. M. Hamer, J. L. den Blaauwen, C. Lambrechts, I. Schoneveld, R. van Driel, and A. P. Otte. 1995. Polycomb and bmi-1 homologs are expressed in overlapping patterns in Xenopus embryos and are able to interact with each other. Mech. Dev. 53:35-46.
43. Simon, J., A. Chiang, and W. Bender. 1992. Ten different Polycomb group genes are required for spatial control of the abd-A and Abd-B homeotic products. Development 114:493-505.
44. Soto, M. C., T.-B. Chou, and W. Bender. 1995. Comparison of germ-line mosaics of genes in the Polycomb group of Drosophila melanogaster. Genetics 140:231-243.
45. Struhl, G., and M. E. Akam. 1985. Altered distribution of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila. EMBO J. 4:3259-3264.
46. + gene product in the determination of segments in Drosophila. Cell 31:285-292.
47. Strutt, H., and R. Paro. 1997. The polycomb group protein complex of Drosophila melanogaster has different compositions at different target genes. Mol. Cell. Biol. 17:6773-6783.
48. Tagawa, M., T. Sakamoto, K. Shigemoto, H. Matsubara, Y. Tamura, T. Ito, I. Nakamura, A. Okitsu, K. Imai, and M. Taniguchi. 1990. Expression of novel DNA-binding protein with zinc finger structure in various tumor cells. J. Biol. Chem. 265:20021-20026.
49. van der Lugt, N. M. T., M. J. Alkema, A. Berns, and J. Deschamps. 1996. The Polycomb-group homologue Bmi-1 is a regulator of murine Hox expression. Mech. Dev. 58:153-164.
50. van Lohuizen, M., M. Frasch, E. Wientjens, and A. Berns. 1991. Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2. Nature 353:353-355.
51. Wismar, J., T. Loffler, N. Habtermichael, O. Vef, M. Geissen, R. Zirwes, W. Altmeyer, H. Sass, and E. Gateff. 1995. The Drosophila melanogaster tumor suppressor gene lethal(3)malignant brain tumor encodes a proline-rich protein with a novel zinc finger. Mech. Dev. 53:141-154.
52. Yu, H., J. K. Chen, S. Feng, D. C. Dalgarno, A. W. Brauer, and S. L. Schreiber. 1994. Structural basis for the binding of proline-rich peptides to SH3 domains. Cell 76:933-945.