Predicting the evolution of antibiotic resistance genes

Nature Reviews Microbiology

Volumn 2, Issue 5, 2004, Pages 430-435

  Hall, Barry G ^a,b  

^a UNIVERSITY OF ROCHESTER   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMPICILLIN; ANTIBIOTIC AGENT; BACTERIAL DNA; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEFEPIME; DNA; GENTAMICIN; IMIPENEM; KANAMYCIN; LINEZOLID; METICILLIN; PENICILLIN G; TOBRAMYCIN; VANCOMYCIN; ANTIINFECTIVE AGENT;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL GENETICS; BACTERIAL INFECTION; CITROBACTER FREUNDII; COMPUTER PROGRAM; COMPUTER SIMULATION; DNA REPLICATION; DRUG MARKETING; DRUG MISUSE; DRUG USE; ENTEROCOCCUS FAECIUM; EVOLUTION; GENE LIBRARY; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC SCREENING; HEALTH CARE POLICY; HUMAN; IN VITRO STUDY; MEDICAL ASSESSMENT; MEDICAL DECISION MAKING; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR MECHANICS; MULTIDRUG RESISTANCE; NONHUMAN; PHYLOGENY; PREDICTION; PRIORITY JOURNAL; PROTEIN ENGINEERING; SALMONELLA ENTERICA; SHIGELLA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; ANIMAL; DIRECTED MOLECULAR EVOLUTION; GENETIC SELECTION; GENETICS; METHODOLOGY; REVIEW;

BACTERIA (MICROORGANISMS); CITROBACTER; CITROBACTER FREUNDII; ENTEROCOCCUS; ENTEROCOCCUS FAECIUM; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; SALMONELLA; SALMONELLA ENTERICA; SHIGELLA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; DIRECTED MOLECULAR EVOLUTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; SELECTION (GENETICS);

EID: 2442549622     PISSN: 17401526     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrmicro888     Document Type: Article

References (23)

1. Palumbi, S. R. Humans as the world's greatest evolutionary force. Science 293, 1786-1790 (2001).
2. Harrison, P. F. & Lederberg, J. (eds) Antimicrobial Resistance: Issues and Options (National Academy Press, Washington DC, 1998).
3. Interagency Task Force on Antimicrobial Resistance. A public health action plan to combat antimicrobial resistance, [online], (1999).
4. National Antimicrobial Resistance Monitoring System Annual Report 2000 [online], (2000).
5. Walsh, C. Where will new antibiotics come from? Nature Rev. Microbiol. 1, 65-70 (2003).
6. Hall, R. M. & Stokes, H. W. Integrons: novel DNA elements which capture genes by site-specific recombination. Genetica 90 115-132 (1993).
7. Livermore, D. Can better prescribing turn the tide of resistance? Nature Rev. Microbiol. 2, 73-78 (2004).
8. CDC Interagency Public Health Action Plan 2001 Annual Report [online], (2001).
9. Galewitz, P. Pharmacia and Upjohn readies new antibiotic. [onlinel, (1999).
10. Stemmer, W. P. C. Rapid evolution of a protein in vitro by DNA shuffling. Nature 370, 389-390 (1994).
11. Barlow, M. & Hall, B. G. Predicting evolutionary potential: in vitro evolution accurately reproduces natural evolution of the TEM β-lactamase. Genetics 160, 823-832 (2002).
12. Barlow, M. & Hall, B. G. Experimental prediction of the natural evolution of antibiotic resistance. Genetics 163, 1237-1241 (2003).
13. Barlow, M. & Hall, B. G. Experimental prediction of the evolution of cefepime resistance from the CMY-2 AmpC β-lactamase. Genetics 164, 23-29 (2003).
14. Salipante, S. J. & Hall, B. G. Determining the limits of the evolutionary potential of an antibiotic resistance gene. Mol. Biol. Evol. 20, 653-659 (2003).
15. Hall, B. G. In vitro evolution predicts that the IMP-1 metallo-β-lactamase does not have the potential to evolve increased activity toward imipenem. Antimicrob. Agents Chemother. 48, 1032-1033 (2004).
16. Barlow, M. & Hall, B. G. Origin and evolution of the AmpC β-lactamases of Citrobacter freundii. Antimicrob. Agents Chemother. 46, 1190-1198 (2002).
17. Barlow, M. & Hall, B. G. Phylogenetic analysis shows that the OXA β-lactamase genes have been on plasmids for millions of years. J. Mol. Evol. 55, 314-321 (2002).
18. Hall, B. G., Salipante, S. J. & Barlow, M. The metallo-β-lactamases fall into two distinct phylogenetic groups. J. Mol. Evol. 57, 249-254 (2003).
19. Hall, B. G. & Barlow, M. Structure-based phylogenies of the serine β-lactamases. J. Mol. Evol. 57, 255-260 (2003).
20. Hall, B. G., Salipante, S. J. & Barlow, M. Independent origins of the subgroup (B1 + B2) and the subgroup B3 metallo-β-lactamases. J. Mol. Evol. (in the press).
21. Magnet, S., Courvalin, P. & Lambert, T. Activation of the cryptic aac(6′)-ly aminoglycoside resistance gene of Salmonella by a chromosomal deletion generating a transcriptional fusion. J. Bacteriol. 181, 6650-6655 (1999).
22. Podglajen, I., Breuil, J., Bordon, F., Gutmann, L. & Collatz, E. A silent carbapenemase gene in strains of Bacteroides fragilis can be expressed after a one-step mutation. FEMS Microbiol. Lett. 70, 21-29 (1992).
23. Salipante, S. J., Barlow, M. & Hall, B. G. GeneHunter: a transposon tool for the identification and isolation of cryptic antibiotic resistance genes. Antimicrob. Agents. Chemother. 47 3840-3845 (2004).