Synthesis and structure-activity relationships of 3-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridines as novel antitumor agents

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 12, 2004, Pages 3189-3193

  Tsuzuki, Yasunori ^a   Tomita, Kyoji ^a   Sato, Yuji ^a   Kashimoto, Shigeki ^a   Chiba, Katsumi ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 CARBOXYL 1,8 NAPHTHYRIDINE; 3 FORMYL 1,8 NAPHTHYRIDINE; ANTINEOPLASTIC AGENT; NAPHTHYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; LEUKEMIA P388; MICE; NAPHTHYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

MURINAE;

EID: 2442543159     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.04.011     Document Type: Article

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