Synthesis and Structure-Activity Relationships of Novel 7-Substituted 1,4-Dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic Acids as Antitumor Agents. Part 2

Journal of Medicinal Chemistry

Volumn 47, Issue 8, 2004, Pages 2097-2109

  Tsuzuki, Yasunori ^a   Tomita, Kyoji ^a   Shibamori, Koh Ichiro ^a   Sato, Yuji ^a   Kashimoto, Shigeki ^a   Chiba, Katsumi ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3 AMINO 1 PYRROLIDINYL) 2 FLUORO 4 OXO 4H QUINO[8,1A,1 B,C][1,4]BENZOXAZINE 5 CARBOXYLIC ACID; 1,4 DIHYDRO 4 OXO (2 THIAZOLYL) 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1,4 DIHYDRO 7 (3 METHOXY 4 METHYLAMINO 1 PYRROLIDINYL) 4 OXO 1 (2 THIAZOLYL) 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1,8 NAPHTHYRIDINE DERIVATIVE; 3 AMINO 1 (3 AMINO 1 PYRROLIDINYL) 2 FLUORO 4 OXO 4H QUINO[8,1A,1 B,C][1,4]BENZOXAZINE 5 CARBOXYLIC ACID; 3 METHOXY 4 METHYLAMINOPYRROLIDINYL DERIVATIVE; 6 FLUORO 1,4 DIHYDRO 4 OXO 1 (2 THIAZOLYL) 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 7 (3 AMINO 1 PYRROLIDINYL) 1,4 DIHYDRO 4 OXO 1 (2 THIAZOLYL) 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 7 (3 AMINOPYRROLIDINYL) DERIVATIVE; A 65282; AG 7352; ANTINEOPLASTIC AGENT; CISPLATIN; CP 115953; DOXORUBICIN; ETOPOSIDE; FLUORINE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG; WIN 57294;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; ISOMER; LEUKEMIA; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; NAPHTHYRIDINES; NEOPLASM TRANSPLANTATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TRANSPLANTATION, HETEROLOGOUS; TRIAZOLES;

EID: 1842607305     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0304966     Document Type: Article

References (28)

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