DNA double-strand breaks, recombination and synapsis: The timing of meiosis differs in grasshoppers and flies

EMBO Reports

Volumn 5, Issue 4, 2004, Pages 385-391

  Viera, Alberto ^a   Santos, Juan L ^b   Page, Jesús ^a   Parra, M Theresa ^a   Calvente, Adela ^a   Cifuentes, Marta ^a   Gómez, Rocío ^a   Lira, Renee ^a,c   Suja, José A ^a   Rufas, Julio S ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

H2AX; Grasshopper; Meiosis; Rad51; Recombination; SMC3; Synapsis

Indexed keywords

COHESIN; DOUBLE STRANDED DNA; HISTONE H2A; RAD51 PROTEIN; RECOMBINASE;

ANIMAL CELL; ARABIDOPSIS; ARTICLE; CHROMOSOME PAIRING; CONTROLLED STUDY; DNA RECOMBINATION; DNA STRAND BREAKAGE; DROSOPHILA MELANOGASTER; FLY; GENE LOCUS; GRASSHOPPER; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOLOCALIZATION; INSECT; MALE; MEIOSIS; MOUSE; NONHUMAN; PACHYTENE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SPERMATOGENESIS; SYNAPTONEMAL COMPLEX; X CHROMOSOME;

ANIMALS; CHROMOSOME PAIRING; DIPTERA; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; GRASSHOPPERS; HISTONES; IMMUNOBLOTTING; MALE; MEIOSIS; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; SPERMATOCYTES;

ARABIDOPSIS; DROSOPHILA MELANOGASTER; HEXAPODA; MELANOGASTER;

EID: 2442526791     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400112     Document Type: Article

References (25)

1. Barlow EL, Benson FE, West SC, Hultén MA (1997) Distribution of the Rad51 recombinase in human and mouse spermatocytes. EMBO J 16: 5207-5215
2. Celeste A, Fernández-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, Bonner RF, Bonner WM, Nussenzweig A (2003) Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol 5: 675-679
3. Downs JA, Lowndes NF, Jackson SP (2000) A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature 408: 1001-1004
4. Dernburg AF, McDonald K, Moulder G, Barstead G, Dresser M, Villeneuve AM (1998) Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis. Cell 94: 387-398
5. Fernández-Capetillo O, Mahadevaiah SK, Celeste A, Romanienko PJ, Camerini-Otero RD, Bonner WM, Manova K, Burgoyne PS, Nussenzweig A (2003) H2AX is required for chromatin remodelling and inactivation of sex chromosomes in male mouse meiosis. Dev Cell 4: 497-508
6. Grelon M, Vezon D, Gendrot G, Pelletier G (2001) AtSPO11-1 is necessary for meiotic recombination in plants. EMBO J 20: 589-600
7. Hamer G, Roepers-Gajadien LP, van Duyn-Goedhart A, Gademan IS, Kal HB, van Buul PPW, de Rooij DG (2003) DNA double-strand breaks and γ-H2AX signaling in the testis. Biol Reprod 68: 628-634
8. Hirano T (2002) The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair. Genes Dev 16: 399-414
9. Kleckner N (1996) Meiosis: how could it work? Proc Natl Acad Sci USA 93: 8167-8174
10. Jang JK, Sherizen DE, Bhagat R, Manheim EA, McKim KS (2003) Relationship of DNA double-strand breaks to synapsis in Drosophila. J Cell Sci 116: 3069-3077
11. Jones GH, Croft JA (1986) Surface spreading of synaptonemal complexes in locusts: zygotene pairing behaviour. Chromosoma 93: 489-495
12. Madigan JP, Chotkoswski HL, Glaser RL (2002) DNA double-strand break-induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation-induced apoptosis. Nucleic Acids Res 30: 3698-3705
13. Mahadevaiah SK, Turner JM, Baudat F, Rogakou EP, de Boer P, Blanco-Rodriguez J, Jasin M, Keeney S, Bonner WM, Burgoyne PS (2001) Recombinational DNA double strand breaks in mice precede synapsis. Nat Genet 21: 271-276
14. McKim KS, Hayasi-Hagihara A (1998) Mei-W68 in Drosophila melanogaster encodes a Spo11 homolog: evidence that the mechanism for initiating meiotic recombination is conserved. Genes Dev 12: 2932-2942
15. Page J, Suja JA, Santos JL, Rufas JS (1998) Squash procedure for protein immunolocalization in meiotic cells. Chromosome Res 6: 639-642
16. Page J, Berríos S, Rufas JS, Parra MT, Suja JA, Heyting C, Fernández-Donoso R (2003) The pairing of X and Y chromosomes during meiotic prophase in the marsupial species Thylamys elegans is maintained by a dense plate developed from their axial elements. J Cell Sci 116: 551-560
17. Parra MT, Page J, Yen TJ, He D, Valdeolmillos A, Rufas JS, Suja JA (2002) Expression and behaviour of CENP-E at kinetochores during mouse spermatogenesis. Chromosoma 111: 53-61
18. Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM (2000) A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 10: 886-895
19. Pelttari J et al (2001) A meiotic chromosome core consisting of cohesin complex proteins recruits DNA recombination proteins and promotes synapsis in the absence of an AE in mammalian meiotic cells. Mol Cell Biol 21: 5667-5677
20. Redon C, Pilch D, Rogakou EP, Sedelnikova O, Newrock K, Bonner WM (2002) Histone HA2 variants H2X and H2Z. Curr Opin Genet Dev 12: 162-169
21. Roeder GS (1997) Meiotic chromosomes: it takes two to tango. Genes Dev 11: 2600-2621
22. Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM (1998) DNA double-stranded breaks induce histone H2AX phosphorylation in serine 139. J Biol Chem 273: 5858-5868
23. Rogakou EP, Nieves-Neira W, Boon C, Pommier Y, Bonner WM (2000) Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139. J Biol Chem 275: 9390-9395
24. Shinohara A, Ogawa H, Ogawa T (1992) Rad51 protein involved in repair and recombination in Saccharomyces cerevisiae is a RecA-like protein. Cell 69: 457-470
25. Tarsounas M, Morita T, Pearlman RE, Moens PB (1999) RAD51 and DMC1 form mixed complexes associated with mouse meiotic chromosome cores and synaptonemal complexes. J Cell Biol 147: 207-219