Expression of vascular endothelial growth factor and its receptors Flk-1 and Flt-1 during the regeneration of autotransplanted adrenal cortex in the adrenalectomized rat

Journal of Urology

Volumn 171, Issue 6 I, 2004, Pages 2445-2449

  Taniguchi, Akihisa ^a   Tajima, Toshihiro ^a   Nonomura, Katsuya ^a   Shinohara, Nobuo ^a   Mikami, Atsushi ^b   Koyanagi, Tomohiko ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Sapporo City Institute of Public Health   (Japan)

Author keywords

Adrenal cortex; Rats, Wistar; Regeneration; Transplants; Vascular endothelial growth factor A

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ADRENAL CORTEX; ADRENAL CORTEX CELL; ADRENALECTOMY; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOTRANSPLANTATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REVASCULARIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE REGENERATION;

EID: 2442502763     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000127755.87490.37     Document Type: Article

References (20)

1. Popnikolov, N. K. and Hornsby, P. J.: Subcutaneous transplantation of bovine and human adrenocortical cells in collagen gel in scid mice. Cell Transplant, 8: 617, 1999
2. Teebken, O. E. and Scheumann, G. F.: Differentiated corticosteroid production and regeneration after selective transplantation of cultured and noncultured adrenocortical cells in the adrenalectomized rat. Transplantation, 70: 836, 2000
3. Belloni, A. S., Neri, G., Musajo, F. G., Andreis, P. G., Boscaro, M., D'Agostino, D. et al: Investigations on the morphology and function of adrenocortical tissue regenerated from gland capsular fragments autotransplanted in the musclus gracilis of the rat. Endocrinology, 126: 3251, 1990
4. Waltenberger, J., Claesson-Welsh, L., Siegbahn, A., Shibuya, M. and Heldin, C.-H.: Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem, 269: 26988, 1994
5. Keyt, B. A., Nguyen, H. V., Berleau, L. T., Duarte, C. M., Park, J., Chen, H. et al: Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis. J Biol Chem, 271: 5638, 1996
6. Gille, H., Kowalski, J., Li, B., LeCouter, J., Moffat, B., Zioncheck, T. F. et al: Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants. J Biol Chem, 276: 3222, 2001
7. Vittet, D., Ciais, D., Keramidas, M., De Fraipont, F. and Feige, J. J.: Paracrine control of the adult adrenal cortex vasculature by vascular endothelial growth factor. Endocr Res, 26: 843, 2000
8. Shifren, J. L., Mesiano, S., Taylor, R. N., Ferrara, N. and Jaffe, R. B.: Corticotropin regulates vascular endothelial growth factor expression in human fetal adrenal cortical cells. J Clin Endocrinol Metab, 83: 1342, 1998
9. Ross, M. A., Sander, C. M., Kleeb, T. B., Watkins, S. C. and Stolz, D. B.: Spatiotemporal expression of angiogenesis growth factor receptors during the revascularization of regenerating rat liver. Hepatology, 34: 1135, 2001
10. Vasir, B., Jonas, J. C., Steil, G. M., Hollister-Lock, J., Hasenkamp, W., Sharma, A. et al: Gene expression of VEGF and its receptors Flk-1/KDR and Flt-1 in cultured and transplanted rat islets. Transplantation, 71: 924, 2001
11. Jozkowicz, A., Cooke, J. P., Guevara, I., Huk, I., Funovics, P., Pachinger, O. et al: Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF. Cardiovasc Res, 51: 773, 2001
12. Boerma, M., Bart, C. I. and Wondergem, J.: Effects of ionizing radiation on gene expression in cultured rat heart cells. Int J Radiat Biol, 78: 219, 2002
13. Grunstein, J., Masbad, J. J., Hickey, R., Giordano, F. and Johnson, R. S.: Isoforms of vascular endothelial growth factor act in a coordinate fashion to recruit and expand tumor vasculature. Mol Cell Biol, 20: 7282, 2000
14. Kanellis, J., Fraser, S., Katerelos, M. and Power, D. A.: Vascular endothelial growth factor is a survival factor renal tubular epithelial cells. Am J Physiol Renal Physiol, 278: F905, 2000
15. Sato, T., El-Asaal, O. N., Ono, T., Tamanoi, A., Dhar, D. K. and Nagasue, N.: Sinusoidal endothelial cell proliferation and expression of angiopoietine/Tie family in regenerating rat liver. J Hepatol, 34: 690, 2001
16. Vendeira, P., Magalhaes, M. M. and Magalhaes, M. C.: Autotransplantation of the adrenal cortex: a morphological and autoradiographic study. Anat Rec, 232: 262, 1992
17. Corpechot, C., Barbu, V., Wendum, D., Kinnman, N., Rey, C., Poupon, R. et al: Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. Hepatology, 35: 1010, 2002
18. Mallet, C., Feraud, O., Ouengue-Mbele, G., Gaillard, I., Sappay, N., Vittet, D. et al: Differential expression of VEGF receptors in adrenal atrophy induced by dexamethasone: a protective role of ACTH. Am J Physiol Endocrinol Metab, 284: E156, 2003
19. Kumazaki, K., Nakayama, M., Suehara, N. and Wada, Y.: Expression of vascular endothelial growth factor, placental growth factor, and their receptors Flt-1 and KDR in human placenta under pathologic conditions. Hum Pathol, 33: 1069, 2002
20. Helske, S., Vuorela, P., Carpen, O., Hornig, C., Weich, H. and Halmesmaki, E.: Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies. Mol Hum Reprod, 7: 205, 2001