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Volumn 97, Issue 5, 2004, Pages 506-511

Osteoprotegerin-Receptor Activator of Nuclear Factor-κB Ligand Ratio: A New Approach to Osteoporosis Treatment?

Author keywords

[No Author keywords available]

Indexed keywords

OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN;

EID: 2442492366     PISSN: 00384348     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007611-200405000-00018     Document Type: Review
Times cited : (37)

References (40)
  • 1
    • 0036724145 scopus 로고    scopus 로고
    • Osteoporosis: Trends and intervention
    • Inzerillo AM, Zaidi M. Osteoporosis: Trends and intervention. Mt Sinai J Med 2002;69:220-231.
    • (2002) Mt Sinai J Med , vol.69 , pp. 220-231
    • Inzerillo, A.M.1    Zaidi, M.2
  • 2
    • 0030704306 scopus 로고    scopus 로고
    • Prevalence of low femoral bone density in older U.S. adults from NHANES III
    • Looker AC, Orwoll ES, Johnston CC, et al. Prevalence of low femoral bone density in older U.S. adults from NHANES III. J Bone Miner Res 1997;12:1761-1768.
    • (1997) J Bone Miner Res , vol.12 , pp. 1761-1768
    • Looker, A.C.1    Orwoll, E.S.2    Johnston, C.C.3
  • 3
    • 0027926739 scopus 로고
    • Consensus Development Conference, Hong Kong, April 1-2, 1993
    • Consensus Development Conference, Hong Kong, April 1-2, 1993. Am J Med 1993;95:1S-78S.
    • (1993) Am J Med , vol.95
  • 4
    • 0032847386 scopus 로고    scopus 로고
    • Physiology and pathophysiology of bone remodeling
    • Raisz LG. Physiology and pathophysiology of bone remodeling. Clin Chem 1999;45:1353-1358.
    • (1999) Clin Chem , vol.45 , pp. 1353-1358
    • Raisz, L.G.1
  • 5
    • 0027716654 scopus 로고
    • Anabolic actions of parathyroid hormone on bone
    • Dempster DW, Cosman F, Parisien M, et al. Anabolic actions of parathyroid hormone on bone. Endocr Rev 1993;14:690-709.
    • (1993) Endocr Rev , vol.14 , pp. 690-709
    • Dempster, D.W.1    Cosman, F.2    Parisien, M.3
  • 7
    • 34347367005 scopus 로고    scopus 로고
    • Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact
    • Jimi E, Nakamura I, Amano H, et al. Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact. Endocrinology 1996;137:2187-2190.
    • (1996) Endocrinology , vol.137 , pp. 2187-2190
    • Jimi, E.1    Nakamura, I.2    Amano, H.3
  • 8
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda H, Shima N, Nakagawa N, et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 1998;95: 3597-3602.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3
  • 9
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
    • Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density. Cell 1997; 89:309-319.
    • (1997) Cell , vol.89 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3
  • 10
    • 0032544518 scopus 로고    scopus 로고
    • Osteoclastogenesis inhibitory factor suppresses osteoclast survival by interfering in the interaction of stromal cells with osteoclast
    • Akatsu T, Murakami T, Nishikawa M, et al. Osteoclastogenesis inhibitory factor suppresses osteoclast survival by interfering in the interaction of stromal cells with osteoclast. Biochem Biophys Res Commun 1998; 250:229-234.
    • (1998) Biochem Biophys Res Commun , vol.250 , pp. 229-234
    • Akatsu, T.1    Murakami, T.2    Nishikawa, M.3
  • 11
    • 7344233085 scopus 로고    scopus 로고
    • Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
    • Emery JG, McDonnell P, Burke MB, et al. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 1998;273:14363-14367.
    • (1998) J Biol Chem , vol.273 , pp. 14363-14367
    • Emery, J.G.1    McDonnell, P.2    Burke, M.B.3
  • 12
    • 0033679142 scopus 로고    scopus 로고
    • Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption
    • The American Society for Bone and Mineral Research President's Committee on Nomenclature. Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption. Bone 2000;27:761-764.
    • (2000) Bone , vol.27 , pp. 761-764
  • 13
    • 0032577903 scopus 로고    scopus 로고
    • Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin
    • Mizuno A, Amizuka N, Irie K, et al. Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin. Biochem Biophys Res Commun 1998;247:610-615.
    • (1998) Biochem Biophys Res Commun , vol.247 , pp. 610-615
    • Mizuno, A.1    Amizuka, N.2    Irie, K.3
  • 14
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong YY, Yoshida H, Sarosi I, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999;397:315-323.
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1    Yoshida, H.2    Sarosi, I.3
  • 15
    • 12944262423 scopus 로고    scopus 로고
    • RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
    • Li J, Sarosi I, Yan XQ, et al. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc Natl Acad Sci U S A 2000;97:1566-1571.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1566-1571
    • Li, J.1    Sarosi, I.2    Yan, X.Q.3
  • 16
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T, Takahashi N, Udagawa N, et al. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 1999;20:345-357.
    • (1999) Endocr Rev , vol.20 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3
  • 17
    • 0032578611 scopus 로고    scopus 로고
    • Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenic protein-2, and cytokines
    • Hofbauer LC, Dunstan CR, Spelsberg TC, et al. Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenic protein-2, and cytokines. Biochem Biophys Res Commun 1998;250:776-781.
    • (1998) Biochem Biophys Res Commun , vol.250 , pp. 776-781
    • Hofbauer, L.C.1    Dunstan, C.R.2    Spelsberg, T.C.3
  • 18
    • 0033304632 scopus 로고    scopus 로고
    • Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells
    • Hofbauer LC, Khosla S, Dunstan CR, et al. Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology 1999;140:4367-4370.
    • (1999) Endocrinology , vol.140 , pp. 4367-4370
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3
  • 19
    • 85047681459 scopus 로고    scopus 로고
    • 17β-Estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-α
    • Saika M, Inoue D, Kido S, et al. 17β-Estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-α. Endocrinology 2001;142:2205-2212.
    • (2001) Endocrinology , vol.142 , pp. 2205-2212
    • Saika, M.1    Inoue, D.2    Kido, S.3
  • 20
    • 0033690895 scopus 로고    scopus 로고
    • The mechanisms of estrogen regulation of bone resorption
    • Riggs BL. The mechanisms of estrogen regulation of bone resorption. J Clin Invest 2000;106:1203-1204.
    • (2000) J Clin Invest , vol.106 , pp. 1203-1204
    • Riggs, B.L.1
  • 21
    • 0031735152 scopus 로고    scopus 로고
    • Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells
    • Horwood NJ, Elliott J, Martin TJ, et al. Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells. Endocrinology 1998;139:4743-4746.
    • (1998) Endocrinology , vol.139 , pp. 4743-4746
    • Horwood, N.J.1    Elliott, J.2    Martin, T.J.3
  • 22
    • 0033305046 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclast-like cell formation
    • Lee SK, Lorenzo JA. Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclast-like cell formation. Endocrinology 1999;140:3552-3561.
    • (1999) Endocrinology , vol.140 , pp. 3552-3561
    • Lee, S.K.1    Lorenzo, J.A.2
  • 23
    • 0034014375 scopus 로고    scopus 로고
    • In vivo demonstration that human parathyroid hormone 1-38 inhibits the expression of osteoprotegerin in bone with the kinetics of an immediate early gene
    • Onyia JE, Miles RR, Yang X, et al. In vivo demonstration that human parathyroid hormone 1-38 inhibits the expression of osteoprotegerin in bone with the kinetics of an immediate early gene. J Bone Miner Res 2000;15:863-871.
    • (2000) J Bone Miner Res , vol.15 , pp. 863-871
    • Onyia, J.E.1    Miles, R.R.2    Yang, X.3
  • 24
    • 0028922164 scopus 로고
    • The role of prostaglandins in the regulation of bone metabolism
    • Kawaguchi H, Pilbeam CC, Harrison JR, et al. The role of prostaglandins in the regulation of bone metabolism. Clin Orthop 1995;313:36-46.
    • (1995) Clin Orthop , vol.313 , pp. 36-46
    • Kawaguchi, H.1    Pilbeam, C.C.2    Harrison, J.R.3
  • 25
    • 0024500787 scopus 로고
    • Prostaglandins promote osteoclastlike cell formation by a mechanism involving cyclic adenosine 3′, 5′-monophosphate in mouse bone marrow cell cultures
    • Akatsu T, Takahashi N, Debari K, et al. Prostaglandins promote osteoclastlike cell formation by a mechanism involving cyclic adenosine 3′, 5′-monophosphate in mouse bone marrow cell cultures. J Bone Miner Res 1989;4:29-35.
    • (1989) J Bone Miner Res , vol.4 , pp. 29-35
    • Akatsu, T.1    Takahashi, N.2    Debari, K.3
  • 26
    • 0034618580 scopus 로고    scopus 로고
    • Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-κB ligand: Modulation of the expression by osteotropic factors and cytokines
    • Nakashima T, Kobayashi Y, Yamasaki S, et al. Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-κB ligand: Modulation of the expression by osteotropic factors and cytokines. Biochem Biophys Res Commun 2000;275:768-775.
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 768-775
    • Nakashima, T.1    Kobayashi, Y.2    Yamasaki, S.3
  • 27
    • 0034813643 scopus 로고    scopus 로고
    • Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells
    • Brändström H, Björkman T, Ljunggren O. Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells. Biochem Biophys Res Commun 2001;280:831-835.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 831-835
    • Brändström, H.1    Björkman, T.2    Ljunggren, O.3
  • 28
    • 0028322893 scopus 로고
    • Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic
    • Masferrer JL, Zweifel BS, Manning PT, et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci US A 1994;91:3228-3232.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3228-3232
    • Masferrer, J.L.1    Zweifel, B.S.2    Manning, P.T.3
  • 29
    • 0029843742 scopus 로고    scopus 로고
    • Inhibition of prostaglandin synthesis leads to a change in adherence of mouse osteoclasts from bone to periosteum
    • Marshall MJ, Holt I, Davie MW. Inhibition of prostaglandin synthesis leads to a change in adherence of mouse osteoclasts from bone to periosteum. Calcif Tissue Int 1996;59:207-213.
    • (1996) Calcif Tissue Int , vol.59 , pp. 207-213
    • Marshall, M.J.1    Holt, I.2    Davie, M.W.3
  • 30
    • 0035137818 scopus 로고    scopus 로고
    • Osteoprotegerin is produced when prostaglandin synthesis is inhibited causing osteoclasts to detach from the surface of mouse parietal bone and attach to the endocranial membrane
    • O'Brien EA, Williams JH, Marshall MJ. Osteoprotegerin is produced when prostaglandin synthesis is inhibited causing osteoclasts to detach from the surface of mouse parietal bone and attach to the endocranial membrane. Bone 2001;28:208-214.
    • (2001) Bone , vol.28 , pp. 208-214
    • O'Brien, E.A.1    Williams, J.H.2    Marshall, M.J.3
  • 31
    • 0033304809 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
    • Hofbauer LC, Gori F, Riggs BL, et al. Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 1999;140:4382-4389.
    • (1999) Endocrinology , vol.140 , pp. 4382-4389
    • Hofbauer, L.C.1    Gori, F.2    Riggs, B.L.3
  • 32
    • 0031721590 scopus 로고    scopus 로고
    • Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: Down-regulation by glucocorticoids
    • Vidal NO, Brändström H, Jonsson KB, et al. Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: Down-regulation by glucocorticoids. J Endocrinol 1998;159:191-195.
    • (1998) J Endocrinol , vol.159 , pp. 191-195
    • Vidal, N.O.1    Brändström, H.2    Jonsson, K.B.3
  • 33
    • 0033984313 scopus 로고    scopus 로고
    • The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption
    • Hofbauer LC, Khosla S, Dunstan CR, et al. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res 2000;15:2-12.
    • (2000) J Bone Miner Res , vol.15 , pp. 2-12
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3
  • 34
    • 0033026628 scopus 로고    scopus 로고
    • Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: Increased serum concentrations in postmenopausal women with osteoporosis
    • Yano K, Tsuda E, Washida N, et al. Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: Increased serum concentrations in postmenopausal women with osteoporosis. J Bone Miner Res 1999;14:518-527.
    • (1999) J Bone Miner Res , vol.14 , pp. 518-527
    • Yano, K.1    Tsuda, E.2    Washida, N.3
  • 35
    • 0035094860 scopus 로고    scopus 로고
    • Associations of serum osteoprotegerin levels with diabetes, stroke, bone density, fractures, and mortality in elderly women
    • Browner WS, Lui LY, Cummings SR. Associations of serum osteoprotegerin levels with diabetes, stroke, bone density, fractures, and mortality in elderly women. J Clin Endocrinol Metab 2001;86:631-637.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 631-637
    • Browner, W.S.1    Lui, L.Y.2    Cummings, S.R.3
  • 36
    • 0034996687 scopus 로고    scopus 로고
    • The ratio of messenger RNA levels of receptor activator of nuclear factor κB ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis
    • Fazzalari NL, Kuliwaba JS, Atkins GJ, et al. The ratio of messenger RNA levels of receptor activator of nuclear factor κB ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis. J Bone Miner Res 2001;16: 1015-1027.
    • (2001) J Bone Miner Res , vol.16 , pp. 1015-1027
    • Fazzalari, N.L.1    Kuliwaba, J.S.2    Atkins, G.J.3
  • 37
    • 0034899609 scopus 로고    scopus 로고
    • Serum parathyroid hormone, but not menopausal status, is associated with the expression of osteoprotegerin and RANKL mRNA in human bone samples
    • Seck T, Diel I, Bismar H, et al. Serum parathyroid hormone, but not menopausal status, is associated with the expression of osteoprotegerin and RANKL mRNA in human bone samples. Eur J Endocrinol 2001; 145:199-205.
    • (2001) Eur J Endocrinol , vol.145 , pp. 199-205
    • Seck, T.1    Diel, I.2    Bismar, H.3
  • 38
    • 0034816809 scopus 로고    scopus 로고
    • OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats
    • Kostenuik PJ, Capparelli C, Morony S, et al. OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats. Endocrinology 2001;142:4295-4304.
    • (2001) Endocrinology , vol.142 , pp. 4295-4304
    • Kostenuik, P.J.1    Capparelli, C.2    Morony, S.3
  • 39
    • 0031762476 scopus 로고    scopus 로고
    • Hypocalcemic effect of osteoclastogenesis inhibitory factor/osteoprotegerin in the thyroparathyroidectomized rat
    • Yamamoto M, Murakami T, Nishikawa M, et al. Hypocalcemic effect of osteoclastogenesis inhibitory factor/osteoprotegerin in the thyroparathyroidectomized rat. Endocrinology 1998;139:4012-4015.
    • (1998) Endocrinology , vol.139 , pp. 4012-4015
    • Yamamoto, M.1    Murakami, T.2    Nishikawa, M.3
  • 40
    • 0035139584 scopus 로고    scopus 로고
    • The effect of a single dose of osteoprotegerin in postmenopausal women
    • Bekker PJ, Holloway D, Nakanishi A, et al. The effect of a single dose of osteoprotegerin in postmenopausal women. J Bone Miner Res 2001; 16:348-360.
    • (2001) J Bone Miner Res , vol.16 , pp. 348-360
    • Bekker, P.J.1    Holloway, D.2    Nakanishi, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.