Effects of cytokines and heat shock on defensin levels of cultured keratinocytes

Burns

Volumn 30, Issue 4, 2004, Pages 329-333

  Bick, Roger J ^a   Poindexter, Brian J ^a   Bhat, Satyanarayan ^b   Gulati, Salil ^b   Buja, Maximilian ^a   Milner, Stephen M ^b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokines; Defensin; Fluorescent imaging; Heat shock; Keratinocytes

Indexed keywords

ANTIINFECTIVE AGENT; BETA DEFENSIN 2; CYTOKINE; DEFENSIN; GAMMA INTERFERON; INTERLEUKIN 1BETA; PEPTIDE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL FUNCTION; CONTROLLED STUDY; HEAT SHOCK; HYPERTROPHY; INFLAMMATION; KERATINOCYTE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SYNTHESIS; STRESS; TEMPERATURE; VERTICAL STRABISMUS;

BETA-DEFENSINS; CELL SIZE; CELLS, CULTURED; CYTOKINES; HEAT-SHOCK RESPONSE; HUMANS; KERATINOCYTES;

EID: 2442484929     PISSN: 03054179     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.burns.2003.12.009     Document Type: Article

References (18)

1. Fitzwater J., Purdue G.F., Hunt J.L., O'Keefe G.E. The risk factors and time course of sepsis and organ dysfunction after burn trauma. J. Trauma. 54:2003;959-966
2. Lehrer R.I., Ganz T. Defensins of vertebrate animals. Curr. Opin. Immunol. 14:2002;96-102
3. Milner S.M., Ortega M.R. Reduced antimicrobial peptide expression in human burn wounds. Burns. 25:1999;411-413
4. Ortega M.R., Ganz T., Milner S.M. Human beta defensin is absent in burn blister fluid. Burns. 26:2000;724-726
5. Milner S.M., Cole A., Ortega M.R., Bakir M.H., Gulati S., Bhat S., et al. Inducibility of HBD-2 in acute burns and chronic conditions of the lung. Burns. 29:2003;553-555
6. Milner S.M., Poindexter B.J., Buja L.M., Smith C.E., Bick R.J. Localization of human beta-defensin in normal and burned skin by fluorescence deconvolution microscopy. J. Burns Surg. Wound Care [serial online]. 1(1):2002;1. Available from: URL: http://www.journalofburns.com
7. Wray C.J., Mammen J.M., Hasselgran P.O. Catabolic response to stress and potential benefits of nutrition support. Nutrition. 18:2002;971-977
8. Salzman N.H., Ghosh D., Huttner K.M., Paterson Y., Bevins C.L. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. Nature. 422:2003;522-526
9. Akibo Y., Jinbu Y., Noguchi T., Nishimura M., Kusano K., Amaratunga P., et al. Upregulation of human beta-defensin 2 peptide in oral lichen planus, leukoplakia and candidiasis. An immunohistochemical study. Pathol. Res. Pract. 198:2002;537-542
10. Mineshiba F., Takashiba S., Mineshiba J., Matsuura K., Kokeguchi S., Murayama Y. Antibacterial activity of synthetic human B defensin-2 peridonta bacteria. J. Int. Acad. Peridontol. 5:2003;35-40
11. Fahlgren A., Hammarstrom S., Danielsson A., Hammarstrom M.L. Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis. Clin. Exp. Immunol. 131:2003;90-101
12. McDermott A.M., Redfern R.L., Zhang B., Pei Y., Huang L., Proske R.J. Defensin expression by the cornea: multiple signaling pathways mediate IL-1beta stimulation of HBD-2 expression by human corneal epithelial cells. Invest. Opthalmol. Vis. Sci. 44:2003;1859-1865
13. Liu L., Roberts A.A., Ganz T. By IL-1 signaling, monocytes-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. J. Immunol. 170:2003;575-580
14. Wang D., McMillin J.B., Bick R.J., Buja L.M. Response of the neonatal rat cardiomyocyte in culture to energy depletion: effects of cytokines, nitric oxide and heat shock proteins. Lab. Invest. 75:1996;809-818
15. Chang H.R., Bistrian B. The role of cytokines in the catabolic consequences of infection and injury. J. Parenter. Enteral. Nutr. 23:1999;156-166
16. Turnage R.H., Nwariaku F., Murphy J., Schulman C., Wright K., Yin H. Mechanisms of pulmonary microvascular dysfunction during severe burn injury. World J. Surg. 26:2002;848-853
17. Sheng Z. Prevention of multiple organ dysfunction syndromes in patients with extensive deep burns. Chin. J. Traumatol. 5:2002;195-199
18. Plackett T.P., Schilling E.M., Faunce D.E., Chudhry M.A., Witte P.L., Kovacs E.J. Aging enhances lymphocyte cytokine defects after injury. FASEB J. 17:2003;688-689